Real-time ultrasound-guided external intracerebral hemorrhage drain placement
We report a new minimally invasive technique utilizing interventional ultrasound for precise external intracerebral hemorrhage drain (EICHD) placement in pigs. (Source: Military Medical Research)
Source: Military Medical Research - July 1, 2020 Category: International Medicine & Public Health Source Type: research

Neuroregeneration and plasticity: a review of the physiological mechanisms for achieving functional recovery postinjury
AbstractNeuronal networks, especially those in the central nervous system (CNS), evolved to support extensive functional capabilities while ensuring stability. Several physiological “brakes” that maintain the stability of the neuronal networks in a healthy state quickly become a hinderance postinjury. These “brakes” include inhibition from the extracellular environment, intrinsic factors of neurons and the control of neuronal plasticity. There are distinct differences b etween the neuronal networks in the peripheral nervous system (PNS) and the CNS. Underpinning these differences is the trade-off between reduced fu...
Source: Military Medical Research - June 11, 2020 Category: International Medicine & Public Health Source Type: research

Incidence, casualties and risk characteristics of civilian explosion blast injury in China: 2000 —2017 data from the state Administration of Work Safety
ConclusionsThe incidence and civilian casualties due to explosions remain unacceptabe in developing China. Measures that mitigate the risk factors are of urgently required. (Source: Military Medical Research)
Source: Military Medical Research - June 10, 2020 Category: International Medicine & Public Health Source Type: research

Incidence and risk factors associated with injuries during static line parachute training in Royal Thai Army
ConclusionsTo prevent military static line parachute injuries, the following factors should be taken into consideration: type of aircraft, aircraft exit, time of the day, equipment, motion sickness and wind speed.Trial registrationThe project was certified by the Research Ethics Committee, Faculty of Medicine, Chulalongkorn University (IRB No. 697/60). (Source: Military Medical Research)
Source: Military Medical Research - June 6, 2020 Category: International Medicine & Public Health Source Type: research

Pattern of liver injury in adult patients with COVID-19: a retrospective analysis of 105 patients
ConclusionsElevated liver function index is very common in patients with COVID-19 infection, and the level were less than 3  × ULN, but most are reversible. The abnormality of 2 or more indexes is low in the patients with COVID-19, but it is more likely to occur in the severe group. (Source: Military Medical Research)
Source: Military Medical Research - June 6, 2020 Category: International Medicine & Public Health Source Type: research

Models to predict injury, physical fitness failure and attrition in recruit training: a retrospective cohort study
ConclusionAttrition rate was similar between 28-day and 80-day courses. In comparison to the 80-day full course, the 28-day course had a lower rate of injury but a higher number of injuries per person-year and of fitness test failure. These findings suggest fitness level at the commencement of training is a critically important factor to consider when designing the course curriculum, particularly short courses. (Source: Military Medical Research)
Source: Military Medical Research - June 2, 2020 Category: International Medicine & Public Health Source Type: research

Effects of Mycobacterium vaccae vaccine in a mouse model of tuberculosis: protective action and differentially expressed genes
ConclusionsM. vaccae vaccine provided good protection in mice againstM. tuberculosis infection, via a highly complex set of molecular changes. Our findings may provide clue to guide development of more effective vaccine against tuberculosis. (Source: Military Medical Research)
Source: Military Medical Research - June 2, 2020 Category: International Medicine & Public Health Source Type: research

Practice parameters for the use of actigraphy in the military operational context: the Walter Reed Army Institute of Research Operational Research Kit-Actigraphy (WORK-A)
ConclusionsDefault actigraphy methods are not the most accurate methods for characterizing soldier sleep, but reliable methods for characterizing operational sleep patterns is a necessary first step in developing strategies to improve soldier readiness. The WORK-A addresses this knowledge gap by providing practice parameters and a robust variety of measures with which to profile sleep behavior in service members. (Source: Military Medical Research)
Source: Military Medical Research - May 30, 2020 Category: International Medicine & Public Health Source Type: research

Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey
ConclusionThe main perceived mode of transmission was not maintaining protection when working at a close distance and having intimate contact with infected cases. Positive psychological intervention is necessary. (Source: Military Medical Research)
Source: Military Medical Research - May 10, 2020 Category: International Medicine & Public Health Source Type: research

Sequential intraventricular injection of tigecycline and polymyxin B in the treatment of intracranial Acinetobacter baumannii infection after trauma: a case report and review of the literature
ConclusionsThe polymyxin B IV  + IVT pathway is an ideal treatment strategy for XDRA. baumannii. The tigecycline IVT pathway is also a safe treatment option. (Source: Military Medical Research)
Source: Military Medical Research - May 9, 2020 Category: International Medicine & Public Health Source Type: research

Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines
AbstractThe coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support or eventually succumb to the illness. The outbreak is managed by a combination of disease containment via public health measures and supportive care for those who are affected. To date, there is no specific anti-COVID-19 treatment. However, the urgency to identify treatments that could turn the tide has led to the emergence of several investigational drugs as potential candidates to improve outcome, especially in the severe to critically ill. While ...
Source: Military Medical Research - May 4, 2020 Category: International Medicine & Public Health Source Type: research

Ex vivo limb perfusion for traumatic amputation in military medicine
AbstractBackgroundLimb loss has a drastic impact on a patient ’s life. Severe trauma to the extremities is common in current military conflicts. Among other aspects, “life before limb” damage control surgery hinders immediate replantation within the short post-traumatic timeframe, which is limited in part by the ischemic time for successful replantation. Ex vivo limb perfusion is currently being researched in animal models and shows promising results for its application in human limb replantation and allotransplantation.Presentation of the hypothesisThe current lack of replantation possibilities in military operation...
Source: Military Medical Research - April 25, 2020 Category: International Medicine & Public Health Source Type: research

Chitosan hydrogel encapsulated with LL-37 peptide promotes deep tissue injury healing in a mouse model
ConclusionChitosan hydrogel encapsulated with LL-37 is biocompatible and could promote the healing of pressure ulcers. (Source: Military Medical Research)
Source: Military Medical Research - April 21, 2020 Category: International Medicine & Public Health Source Type: research

Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19
AbstractSince December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44%. Studies have shown that coagulation dysfunction is a major cause of death in patients with severe COVID-19. Therefore, the People ’s Liberation Army Professional Committee of Critical Care Medicine and Chinese Society on Thrombosis and Hemostasis grouped experts from the frontline of the Wuhan epidemic to come together and develop an expert consensus on diagnosis and...
Source: Military Medical Research - April 19, 2020 Category: International Medicine & Public Health Source Type: research

Fit to fight – from military hygiene to wellbeing in the British Army
AbstractThis paper reviews the historical evolution of the language and organization surrounding the health of personnel in the British Army from ‘hygiene’ through  to ‘wellbeing’. It starts by considering the health of the army in the mid-nineteenth century and the emergence of military hygiene as a professional subject. It continues by looking at advances in military hygiene in the two world wars. Hygiene was replaced by the term ‘ health’ in the 1950s as the collective noun used by professionals working in this field. This unity split when the professions of occupational medicine and public health establish...
Source: Military Medical Research - April 6, 2020 Category: International Medicine & Public Health Source Type: research