RIG-I, a novel DAMPs sensor for myoglobin activates NF- κB/caspase-3 signaling in CS-AKI model

ConclusionRIG-I is a novel damage-associated molecular patterns (DAMPs) sensor for myoglobin and participates in the NF- κB/caspase-3 signaling pathway in CS-AKI. In the development of CS-AKI, specific intervention in the RIG-I pathway might be a potential therapeutic strategy for CS-AKI.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research