13 Atp-sensitive potassium channels mediate the cardioprotection of panax notoginseng saponins against myocardial ischemia reperfusion injury and inflammatory reaction
Conclusion
PNS preconditioning may reduce inflammation to due to MIRI via KATP channels.
Acknowledgements
Supported by a project grant from National Natural Science Foundation (NSFC) of China (Grant No. 81303256). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Ning, K., Jiang, L., Yang, Z., Zheng, Q., Bao, Y. Tags: Abstracts Source Type: research
12 The igca staging system compared with ajcc7 system in stratifying survival of patients with cancer
Conclusions
The IGCA staging system can stratify stage III gastric cancer patients more correctly than the AJCC7 system.
Acknowledgement
Supported by the National Natural Science Foundation of China (Grant No. 14B520013) and the Scientific Research Project from the open fund of Henan Key laboratory (Grant No. 172400410344). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, F. Tags: Abstracts Source Type: research
11 Meta-analysis of prognostic value of transforming growth factor-beta (tgf-{beta}) in patients
Conclusions
This meta-analysis demonstrates that TGF-β can be used as a prognostic biomarker for CRC patients undergoing surgery, especially for CRC patients from Western countries. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, F. Tags: Abstracts Source Type: research
10 Knockdown of transforming growth factor beta regulator 4 (tbrg4) promotes apoptosis in human lung cancer cell line h1299 via regulating ddit3, cav1 and rrm2
Abstract
Transforming growth factor beta regulator 4 (TBRG4) gene is located on 7 p14-p13, a region correlated with many cancer types, such as hematologic malignancies, head and neck squamous cell carcinoma, and multiple myeloma. However, the role of TBRG4 in human lung cancer is largely unknown. Thus, in the present study, the TBRG4 mRNA level was evaluated in the lung cancer cell line H1299 by quantitative PCR (qPCR) after knocking down TBRG4 using lentivirus-mediated small interfering RNA (siRNA). The result showed that TBRG4 was significantly inhibited in H1299 by RNAi. Microarray analysis revealed 586 differentially-e...
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, A., Liu, X., Su, W., Duan, G., Xie, Z., Chu, S. Tags: Abstracts Source Type: research
09 Exploring the genotype-phenotype associations of colorectal cancer using vector space model
Conclusion
Our study provides a biomedical literature mining method for cancer translational research such as construction of a precision medicine knowledge base, biomarker prediction/evaluation, and knowledge discovery in texts.
Acknowledgements
Supported by the National key research and development program of China (No. 2016YFC0901703), and the Public Projects of Zhejiang Province, China (No. 2017C33064). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Deng, N., NK, D., Feng, Y., Wang, Z., Duan, H., Liu, F. Tags: Abstracts Source Type: research
