03 Three-templates molecularly imprinted solid-phase microextraction coatings for parabens analysis in river water samples
ConclusionThe three-templates molecularly imprinted solid-phase microextraction coatings can selectively extract three parabens in real water samples.AcknowledgementsSupported by a project grant from the National Natural Science Foundation of China (Grant No. 21565018). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - December 5, 2017 Category: Research Authors: Ma, X., Liu, Z., Xu, Z. Tags: Abstracts Source Type: research
02 Brain cancer prediction using machine learning methods and high-throughput molecular data
ConclusionOur study developed machine learning based models to predict GBM survival. The combination of molecular data and clinical variables can improve prediction accuracy. Moreover, it also brings us new insights into the molecular mechanisms underlying GBM cancer.AcknowledgementsSupported by the National Natural Science Foundation of China (61471078, 31270903), the Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry, the Program for Liaoning Excellent Talents in University (LJQ2015011) and the Fundamental Research Funds for the Central Universities (3132016330, 3132014306...
Source: Journal of Investigative Medicine - December 5, 2017 Category: Research Authors: Ma, B., Chang, Q., Geng, Y., Liu, G., Dong, H., Sun, Y. Tags: Abstracts Source Type: research
01 Adsorption and wetting of protein affected by bionic surface texture desig nfor artificial organs application
ConclusionBionic surface texture has obvious influence on the adsorption and wetting of protein. Proper parameters of bionic surface texture may be of importance for the surface design in the real specific application.AcknowledgmentSupported by a project grant from the Science and Technology Innovation Fund (Grand No. 2014kct-03). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - December 5, 2017 Category: Research Authors: W, W., BX, F., GM, C. Tags: Abstracts Source Type: research
25 Culture environmental management innovation optimisation of enrichment factor lactobacillus acidophilus
Conclusions
The best ratio of enrichment medium was: glutamate, lysine, vitamin C. Culture temperature was 37°C, initial fermentation pH was 6.5, 4% inoculation, harvest time was 20 hours after fermentation.
Acknowledgements
Supported by a project grant from Longdong University doctoral research (Grant No. XYBE1605). Central finance forestry science and technology extension demonstration project [2015] ZYTG8 Qingyang science and technology support program (NK2011-41). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Li, X., Wang, D., Zhang, Z., Zhu, Y., Jia, H. Tags: Abstracts Source Type: research
24 Danggui shaoyao powder improves diabetic nephropathy without altering blood glucose in streptozotocin-induced diabetic rats
Conclusion
This study suggests that DSS could improve renal function in streptozotocin-induced DN model rats. The mechanism may be related to regulating the Th1/Th2 cell balance and improved lipid metabolism in DN rats.
Acknowledgment
Supported by a project grant from The National Natural Science Foundation of China (Grant No. 81603527), Science and technology project of Henan Province (Grant No. 162102310466), Key scientific research projects of Henan Province Colleges and Universities (Grant No. 16A360010), Henan University of Traditional Chinese Medicine Scientific and technological innovation talent support program (G...
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Li, X., Li, Z., Zhang, L., Zhang, Y., Liu, X., Zhao, X., Liu, W., Gao, A. Tags: Abstracts Source Type: research
23 Study on mirnas prediction and co-expression patterns of the human intronic mirnas with their host genes
Conclusions
This study not only provides some effective means for research on miRNAs prediction and co-expression prediction of intronic miRNAs with their host genes, but also gives some solid foundation for future research in this field.
Acknowledgements
Supported by the National Natural Science Foundation of China (Grant No. 61402099). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, H., Li, B., Wu, M. Tags: Abstracts Source Type: research
22 In vivo evaluation of ethanol extract of forsythia suspensa (thunb.) vahl (fruit) in anti-inflammatory and analgesic activities
Conclusions
These findings indicate that FSTV-ET can produce anti-inflammatory and analgesic activities in vivo, and the mechanism is likely to be related to inhibiting lipid peroxidation and inflammation.
Acknowledgements
Supported by project grants from the National Natural Science Foundation of China (Grant No. 81503269), the Funding Scheme for Young Key Teachers of Colleges and Universities in Henan Province (Grant No. 2014GGJS-072), and the Science and Technology Project of Zhengzhou (Grant No. 20150309). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, J., Cui, Y., Chen, S., XB, L., Feng, W., Cai, H., Chen, R. Tags: Abstracts Source Type: research
21 Effect of jinjiang granules on intestinal mucosal immunity in mice model
Conclusions
Jinjiang granules can improve the immune function of the mice models of hypoimmunity. It also improves intestinal immune function. It prevents colds when given as the initial medicine.
Acknowledgements
The Central Plains scholars (162101510003), the team of outstanding scientific and technological innovation in Henan province (TCJ2014-391), Henan University of Traditional Chinese Medicine and deep processing of geoherbs Collaborative Innovation Centre (2012)188–2. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Miao, M., Cao, L., Qiao, J., Zhang, R. Tags: Abstracts Source Type: research
20 Gut microbiota in human adults with irritable bowel syndrome differs from healthy controls
Conclusion
There were differences in faecal microbiota between IBS patients and healthy controls. The faecal microbiota of patients with IBS is associated with significant increases in detrimental and decreases in beneficial bacterial groups.
Acknowledgment
Supported by grants from National Program on Key Basic Research Project (973 Program, 2013CB531405), and the National Natural Science Foundation of China (NSFC, No. 81641029 and 81370113). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Liu, Y., Wang, Y., Wen, S., Zhang, T., Tang, L. Tags: Abstracts Source Type: research
19 Experimental study on postoperative adhesions between tendon and different tissues
Conclusion
Postoperative adhesions between the tendon and different tissues differ. More tissue adhesion formed between the tendon and the subcutaneous tissue than between the tendon and the remnant sheath. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Su, Y., Wang, W., Meng, X., Gu, G., Yu, M., Yan, Z., Ma, Y., Dong, X., Sun, Q., Zhao, D. Tags: Abstracts Source Type: research
18 Intermittent hypoxia improves atherosclerosis associated with upregulation of hif-1{alpha} and nf-{kappa}b in aortic arch and serum of rabbits
Conclusions
IH may, through increased HIF-1α and NF-B in rabbits, lead to lipid deposition, which leads to the formation of atherosclerosis and the occurrence of cardiovascular and cerebrovascular diseases. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Pang, J., Wang, B., Li, Y., Zhang, H., Xiang, W., Hao, X., Xue, H. Tags: Abstracts Source Type: research
17 Effect of salvia miltiorrhiza on tmmrna expression in coronary artery tissue of rats with high salt induced blood stasis
Conclusion
Salvia miltiorrhiza can reduce the expression of TMmRNA in the tissue of blood stasis caused by high salt, promote the repair of blood vessel endothelium and blood movement, and can effectively improve the damaged coronary artery.
Acknowledgements
Supported by a project grant from Natural Science Foundation of China (Grant No. 81503476). (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Xia, L., Zhou, X., Tian, X., Zhao, Y., Fu, D., Xu, H. Tags: Abstracts Source Type: research
16 The intervention effect of total flavonoids of mao dongqing on cerebral ischaemic tolerance model in mice
Conclusion
Ischaemic preconditioning can induce cerebral ischaemic tolerance. The total flavonoids of Mao Dongqing and ischaemic preconditioning have a synergistic effect by inhibition of the overexpression of immediate early gene c-fos, COX-2 and improved platelet function. It can reduce brain injury and promote the formation of cerebral ischaemic tolerance. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Lou, X., Bai, M., Qiao, J., Fang, X., Miao, M. Tags: Abstracts Source Type: research
15 Comparison of biomechanical characteristics on barefoot running and shod running
Background
Compared with the rearfoot strike pattern of shod running, barefoot running with a forefoot strike pattern will change the kinematics and kinetic parameters. This paper analyses the biomechanical differences between barefoot running and shod running and aims to provide a reference for barefoot training and the prevention of sports injury.
Methods
Three-dimensional force plate test and three-dimensional video analysis.
Results
Kinetic characteristics: The F-t curve by the force plate test shows that barefoot running has a smooth curve with a single peak while the F-t curve of shod running has a double peak on t...
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Wang, S., Zhou, J. Tags: Abstracts Source Type: research
14 The mechanism of pkcB-p66shc-nadph oxidase pathway in high glucose induced-oxidative stress in renal tubular epithelial cells
Conclusion
The study clarified a novel mechanism of oxidative stress damaging HK-2 cells via the modulation of the PKCβ-P66Shc-NADPH oxidase pathway. Understanding the molecular pathway of oxidative stress could translate into the development of therapeutic strategies for diabetic nephropathy.
Acknowledgements
This work was supported by the National Natural Science Foundation of China [No. 81400300] and Natural Science Foundation of Jiangsu Province [No. BK20130642]. (Source: Journal of Investigative Medicine)
Source: Journal of Investigative Medicine - November 24, 2017 Category: Research Authors: Cheng, Y., Chao, J., Zhu, D., Liu, B. Tags: Abstracts Source Type: research
