Journal of Clinical Neurophysiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Utility of Quantitative EEG for Seizure Detection in Adults
Summary: Traditional review of EEG for seizure detection requires time and the expertise of a trained neurophysiologist; therefore, it is time- and resource-intensive. Quantitative EEG (qEEG) encompasses a variety of methods to make EEG review more efficient and allows for nonexpert review. Literature supports that qEEG is commonly used by neurophysiologists and nonexperts in clinical practice. In this review, the different types of qEEG trends and spectrograms used for seizure detection in adults, from basic concepts to clinical applications, are discussed. The merits and drawbacks of the most common qEEG trends are d...
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

A Primer on EEG Spectrograms
This article provides an approachable set of first principles to help clinicians understand how spectrograms encode information about the raw EEG and how to interpret spectrograms to efficiently infer underlying EEG patterns. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Decoding the Spectrogram Rainbow
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Guest Editorial Source Type: research

Welcome to the Journal of Clinical Neurophysiology
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: EDITORIAL Source Type: research

Combined VNS-RNS Neuromodulation for Epilepsy
Summary: The vagus nerve stimulator (VNS) and responsive nerve stimulator (RNS) are nonpharmacological devices approved for drug-resistant epilepsy. Vagus nerve stimulator was removed before placing an RNS in clinical trials. Two cases of bilateral mesial temporal epilepsy treated concurrently with VNS and bilateral mesial temporal RNS devices were reported. In each case, the VNS device was turned off temporarily, which allowed for a direct comparison of RNS recordings and efficacy with and without simultaneous VNS stimulation. Temporary VNS cessation lead to increased clinical and electrocorticographic seizures despit...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Case Report Source Type: research

EEG Beta-Band Spectral Entropy Can Predict the Effect of Drug Treatment on Pain in Patients With Herpes Zoster
Conclusions: EEG beta-band power spectral entropy in the central–parietal region is predictive of the effectiveness of drug treatment on herpes zoster patients, and it could potentially be used for early pain management and therapeutic prognosis. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Original Research Source Type: research

EEG Findings in Coronavirus Disease
Conclusions: Our findings underscore previous observations that neurologic manifestations are common in severe cases. COVID-19 patients with epilepsy may have an increased risk of neurological manifestations and abnormal EEG. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Nonepileptic Electroencephalographic Correlates of Episodic Increases in Intracranial Pressure
Conclusions: Cyclic patterns and varying degrees of slowing and attenuation often preceded clinical deterioration associated with intracranial hypertension. Future systematic studies of EEG changes in this setting will facilitate early and noninvasive detection of elevated ICP. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Biomarkers Obtained by Transcranial Magnetic Stimulation in Neurodevelopmental Disorders
Summary: Transcranial magnetic stimulation (TMS) is a method for focal brain stimulation that is based on the principle of electromagnetic induction where small intracranial electric currents are generated by a powerful fluctuating magnetic field. Over the past three decades, TMS has shown promise in the diagnosis, monitoring, and treatment of neurological and psychiatric disorders in adults. However, the use of TMS in children has been more limited. We provide a brief introduction to the TMS technique; common TMS protocols including single-pulse TMS, paired-pulse TMS, paired associative stimulation, and repetitive TMS...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Neurobehavioral Biomarkers: An EEG Family Reunion
Summary: The field of clinical EEG has had an uneasy relationship with the use of this technology for clinical cognitive applications and often for good reason. However, apart from its clinical use, EEG has had a tradition as a major tool in cognitive psychology and cognitive neuroscience dating back at least to the 1960s. Based on accumulated knowledge from its research application, EEG-based biomarkers are beginning to see applications in clinical trials and may eventually enter clinical care. We address concerns surrounding quality control, the treatment of artifact, and normal variants and how developments in engin...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Cognitive Biomarkers in the Clinic: Lessons From Presurgical fMRI
Summary: Cognitive biomarkers are vital and uniquely challenging clinical tools. There has been marked growth in neuroimaging-based cognitive biomarkers across the past 40 years with more in development (e.g., clinical cognitive EEG). The challenges involved in developing cognitive biomarkers and key milestones in their development are reviewed here using clinical functional MRI's evolution as a case study. It is argued that indexing cognition is uniquely challenging because it requires patients to consistently use specific cognitive processes, and it is difficult or impossible to independently verify this occurred. Th...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Searching for a “Brain Signature” of Neurodevelopmental Disorders: Event-Related Potentials and the Quest for Biomarkers of Cognition
Summary: This review summarizes main applications of event-related potentials (ERPs) to the study of cognitive processes in persons with neurodevelopmental disorders, for whom traditional behavioral assessments may not be suitable. A brief introduction to the ERPs is followed by a review of empirical studies using passive ERP paradigms to address three main questions: characterizing individual differences, predicting risk for poor developmental outcomes, and documenting treatment effects in persons with neurodevelopmental disorders. Evidence across studies reveals feasibility of ERP methodology in a wide range of clini...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Interictal Spikes as an EEG Biomarker of Cognitive Impairment
Summary: Although interictal spikes (IISs) are a well-established EEG biomarker for epilepsy, whether they are also a biomarker of cognitive deficits is unclear. Interictal spikes are dynamic events consisting of a synchronous discharge of neurons producing high frequency oscillations and a succession of action potentials which disrupt the ongoing neural activity. There are robust data showing that IISs result in transitory cognitive impairment with the type of deficit specific to the cognitive task and anatomic location of the IIS. Interictal spike, particularly if frequent and widespread, can impair cognitive abiliti...
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Bridges Through the Cloud: Towards Clinical Biomarkers of Cognitive Neurophysiology
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - February 1, 2022 Category: Neurology Tags: Guest Editorial Source Type: research

JCN Book Review: Atlas of Intensive Care Quantitative EEG
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - January 1, 2022 Category: Neurology Tags: Book Review Source Type: research