Cortical Spreading Depression Phenomena Are Frequent in Ischemic and Traumatic Penumbra: A Prospective Study in Patients With Traumatic Brain Injury and Large Hemispheric Ischemic Stroke
Purpose: Spreading depolarization (SD) phenomena are waves of neuronal depolarization, which propagate slowly at a velocity of 1 to 5 mm/minute and can occur in patients with ischemic or hemorrhagic stroke, traumatic brain injury, and migraine with aura. They form part of secondary injury, occurring after spreading ischemia. The purposes of this study were to describe the frequency and characteristics of SD phenomena and to define whether a correlation existed between SD and outcome in a group of patients with TBI and large hemispheric ischemic stroke. Methods: This was a prospective observational study of 39 ad...
Source: Journal of Clinical Neurophysiology - January 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Consistency of Visual Evoked Potential in Extraocular Manifestations of Behcet Disease and Impact of Corticosteroid Treatment
This study included 18 patients (36 eyes) with BD without recent ocular manifestations and 20 healthy controls (40 eyes). Clinical history was taken, and clinical examinations were done. Visual evoked potential recordings were performed by an electromyographic evoked machine for patients and controls. Corticosteroids were given to patients with extraocular activity, and VEP was repeated after clinical and laboratory improvement of the manifestations. Results: p100 latency of VEP was prolonged in 8 patients (11 eyes) (44.4% of cases). Mean p100 latency showed statistically significant prolongations in BD group compar...
Source: Journal of Clinical Neurophysiology - January 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Depression and Fatigue in Patients With Multiple Sclerosis Have No Influence on the Parameters of Cognitive Evoked Potentials
Purpose: The purpose of this study was to examine if depression and fatigue affect event-related brain potentials (ERPs) in patients with relapsing–remitting multiple sclerosis, and to assess the significance of ERP as an indicator of cognitive impairment. Methods: A total of 81 relapsing–remitting multiple sclerosis patients and 32 healthy control subjects participated in the study. Cognitive functions were evaluated using a standard PASAT, the symbol digit modality test, and ERP. The degrees of depressive symptomatology and fatigue were assessed with Beck Depression Inventory, the Fatigue Severity Scale, a...
Source: Journal of Clinical Neurophysiology - January 1, 2021 Category: Neurology Tags: Original Research Source Type: research

The Prognostic Value of Somatosensory Evoked Potentials in Children After Cardiac Arrest: The SEPIA Study
Purpose: Absent cortical somatosensory evoked potentials (SSEPs) reliably predict poor neurologic outcome in adults after cardiac arrest (CA). However, there is less evidence to support this in children. In addition, targeted temperature management, test timing, and a lack of blinding may affect test accuracy. Methods: A single-center, prospective cohort study of pediatric (aged 24 hours to 15 years) patients in which prognostic value of SSEPs were assessed 24, 48, and 72 hours after CA. Targeted temperature management (33–34°C for 24 hours) followed by gradual rewarming to 37°C was used. Somatosensory evoke...
Source: Journal of Clinical Neurophysiology - January 1, 2021 Category: Neurology Tags: Original Research Source Type: research

American Clinical Neurophysiology Society's Standardized Critical Care EEG Terminology: 2021 Version
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - January 1, 2021 Category: Neurology Tags: ACNS Guideline Source Type: research

Pediatric Sleep Pearls
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Book Review Source Type: research

Utilization of MEG Among the US Epilepsy Centers: A Survey-Based Appraisal
Conclusions: Only the centers with larger surgical volumes incorporate MEG regularly in presurgical evaluation of patients with drug-resistant epilepsy. A reversal of the pervasive underutilization of epilepsy surgery can benefit from MEG, but this requires a sustained concerted promotion by the epilepsy and MEG communities. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Original Research Source Type: research

Clinical Magnetoencephalography Practice in the United States Ten Years Later: A Survey-Based Reappraisal
Conclusions: A plateau in MEG volumes suggests that MEG has not become a part of the standard of care, and correspondingly, the Clinical Practice Guidelines appeared to have had little impact on clinical practice. The American Clinical Magnetoencephalography Society must continue to engage magnetoencephalographers, potential referrers, and vendors. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

Visual Mapping With Magnetoencephalography: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines
Summary: Using visual evoked fields (VEFs) to differentiate healthy, normal brain function from dysfunctional cortex has been demonstrated to be both valid and reliable. Currently, VEFs are widely implemented to guide intracranial surgeries for epilepsy and brain tumors. There are several areas of possible future clinical use of VEFs, including early identification of disorders, such as multiple sclerosis, Parkinson's disease, stroke, and human immunodeficiency virus–associated neurocognitive disorders. These studies have suggested that VEFs could be used to study disease pathophysiology or as a biomarker for early i...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

Auditory Mapping With MEG: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines
Summary: Auditory evoked fields (AEFs) are well suited for studies of auditory processing in patients. Their sources have been localized to Heschl's gyri and to the supratemporal auditory cortices. Auditory evoked fields are known to be modulated by peripheral and central lesions of auditory pathways and to reflect group-level pathophysiology of neurodevelopmental and psychiatric disorders. They are useful in lateralization of language processes for planning neurosurgery and for localization of language-related cortex. The recently developed artifact rejection and movement compensation methods will enhance and extend t...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

Sensorimotor Mapping With MEG: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines
Summary: In this article, we present the clinical indications and advances in the use of magnetoencephalography to map the primary sensorimotor (SM1) cortex in neurosurgical patients noninvasively. We emphasize the advantages of magnetoencephalography over sensorimotor mapping using functional magnetic resonance imaging. Recommendations to the referring physicians and the clinical magnetoencephalographers to achieve appropriate sensorimotor cortex mapping using magnetoencephalography are proposed. We finally provide some practical advice for the use of corticomuscular coherence, cortico-kinematic coherence, and mu rhyt...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

Language Mapping With Magnetoencephalography: An Update on the Current State of Clinical Research and Practice With Considerations for Clinical Practice Guidelines
Summary: Numerous studies have shown that language processing is not limited to a few brain areas. Visual or auditory stimuli activate corresponding cortical areas, then memory identifies the word or image, Wernicke's and Broca's areas support the processing for either reading/listening or speaking and many areas of the brain are recruited. Determining how a normal person processes language helps clinicians and scientist to understand how brain pathologies such as tumor or stroke can affect changes in language processing. Patients with epilepsy may develop atypical language organization. Over time, the chronic nature o...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

MEG Reporting
Summary: The report generated by the magnetoencephalographer's interpretation of the patient's magnetoencephalography examination is the magnetoencephalography laboratory's most important product and is a representation of the quality of the laboratory and the clinical acumen of the personnel. A magnetoencephalography report is not meant to enumerate all the technical details that went into the test nor to fulfill some imagined requirements of the electronic health record. It is meant to clearly and concisely answer the clinical question posed by the referring doctor and to convey the key findings that may inform the n...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

The Value of Source Localization for Clinical Magnetoencephalography: Beyond the Equivalent Current Dipole
Summary: Source localization for clinical magnetoencephalography recordings is challenging, and many methods have been developed to solve this inverse problem. The most well-studied and validated tool for localization of the epileptogenic zone is the equivalent current dipole. However, it is often difficult to summarize the richness of the magnetoencephalography data with one or a few point sources. A variety of source localization algorithms have been developed to more fully explain the complexity of clinical magnetoencephalography data used to define the epileptogenic network. In this review, various clinically avail...
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research

Normal Variants in Magnetoencephalography
This article reviews benign epileptiform variants and provides examples in EEG and magnetoencephalography. In addition, the potential of oscillatory configurations in different frequency bands to appear as epileptic activity is discussed. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2020 Category: Neurology Tags: Invited Review Source Type: research