Journal of Clinical Neurophysiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Recognizing New-Onset Sleep Disorders in Autoimmune Encephalitis Often Prompt Earlier Diagnosis
Summary: Sleep/wake disorders are common in patients with autoimmune encephalitis, sometimes the most prominent or sole initial symptom, then delaying diagnosis. Sleep/wake disorders in autoimmune encephalitis vary and include severe sleeplessness, hypersomnia, central and/or obstructive sleep apnea, rapid eye movement sleep behavior disorder, indeterminate sleep/wake states, and loss of circadian sleep/wake rhythms. N-methyl-d aspartate receptor encephalitis (NMDAR) is often associated with insomnia, then hypersomnia and sleep-related central hypoventilation. Profound sleeplessness and rapid eye movement sleep behavio...
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Sleep Disorders in Traumatic Brain Injury
This study will review the spectrum and proposed mechanisms of TBI-associated sleep disorders and discuss the clinical approach to diagnosis and management of them. Disordered and fragmented sleep with insomnia and daytime sleepiness is very common after TBI. Sleep disruption contributes to morbidity and neurocognitive and neurobehavioral deficits and prolongs the recovery phase after injury. Early recognition and correction of these problems may limit the secondary effects of TBI and improve patient outcomes. Evaluating sleep disorders in TBI should be an important component of TBI assessment and management. Finally, newe...
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

What Is the Prognostic Significance of Rapid Eye Movement Sleep Without Atonia in a Polysomnogram?
Summary: Freud said we are lucky to be paralyzed during sleep, so we cannot act out our dreams. Atonia of skeletal muscles normally present during rapid eye movement sleep prevents us from acting out our dreams. Observing rapid eye movement sleep without atonia in a polysomnogram in older adults first and foremost warrants consideration of rapid eye movement behavior disorder. Seventy-five to 90% of older adults with isolated rapid eye movement behavior disorder will develop a neurodegenerative disease within 15 years, most often a synucleinopathy. Rapid eye movement sleep without atonia in those younger than 50 years ...
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Stroke: What's Sleep Got to Do With It?
Summary: Ischemic strokes most often occur between 6 am and 12 am after awakening from sleep but up to 30% occur during sleep. Wake-up strokes (WUS) are new focal neurological deficit(s) persisting for ≥ 24 hours attributable to an ischemic event present on patient awakening. Obstructive sleep apnea (OSA) is a major risk factor for WUS because it compounds the instability of the morning environment and increases the likelihood of cardiovascular events, including hypertension, atrial fibrillation, right-to-left shunts, and stroke. Circadian-driven alterations in structural, homeostatic, and serological factors also pr...
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Sleep Biomarkers Help Predict the Development of Alzheimer Disease
Summary: Middle-aged or older adults who self-report sleep–wake disorders are at an increased risk for incident dementia, mild cognitive impairment, and Alzheimer disease. Dementia in people with mild cognitive impairment and Alzheimer disease who complain of sleep–wake disorders progress faster than those without sleep–wake disorders. Removal of amyloid-beta and tau tangles occurs preferentially in non-rapid eye movement 3 sleep and fragmented or insufficient sleep may lead to accumulation of these neurotoxins even in preclinical stages. Selective atrophy in the medial temporal lobe on brain MRI has been shown t...
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Night Moves and Modes: Sleep Biomarkers for Neurocognitive Disorders
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2022 Category: Neurology Tags: Guest Editorial Source Type: research

Book Review for Atlas of Artifacts in Clinical Neurophysiology
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Book Review Source Type: research

Hemisphere-Dependent Ictal Tachycardia Versus Ictal Bradycardia in a Critically Ill Patient
Summary: Tachycardia is a common ictal phenomenon; however, ictal bradycardia is less commonly reported and rarely presents as ictal asystole/syncope. In critically ill patients, seizures are much less likely to manifest with overt clinical signs, i.e., are more likely to be subtle or nonconvulsive. In this setting, changes in heart rate may be the only clue that seizures are occurring. The authors report an exemplary case of a 78-year-old right-handed man who presented with spontaneous left frontal intraparenchymal hemorrhages. During standard clinical monitoring in the Neuro-Intensive Care Unit, the patient had discr...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Case Report Source Type: research

Clinical and Electrophysiological Features of Chronic Motor Axonal Neuropathy
Conclusions: Chronic motor axonal neuropathy associated with monosialoganglioside might be a “mild” AMAN with chronic onset by similar clinical and electrophysiological features. There was a unique pattern of nerve involvement presenting as reverse split leg sign in both CMAN and AMAN. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

A Retrospective Study of Ultrasound Accuracy for the Diagnosis of Chronic Inflammatory Demyelinating Polyneuropathy
Conclusion: This study demonstrates that ultrasound can be of diagnostic utility in patients with suspected CIDP, even when conducted in a nonstandardized real-world setting. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Prolonged Exercise Test in Patients With History of Thyrotoxicosis
Purpose: Thyrotoxic periodic paralysis is characterized by recurrent episodes of reversible, severe proximal muscle weakness associated with hypokalemia and hyperthyroidism. Prolonged exercise test is an easy, noninvasive method of demonstrating abnormal muscle membrane excitability in periodic paralyses. Although abnormal in thyrotoxic periodic paralysis patients, the effects thyroid hormone levels in non-thyrotoxic periodic paralysis thyrotoxicosis patients have not been well studied. The study aims to evaluate thyrotoxicosis patients (regardless of thyrotoxic periodic paralysis history) with prolonged exercise test ...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Intraoperative Neuromonitoring of Blink Reflex During Posterior Fossa Surgeries and Its Correlation With Clinical Outcome
Conclusions: We suggest that BR is a valuable intraoperative neuromonitoring method that can be used in addition to facial CoMEPs during skull base surgeries to assess real-time facial nerve integrity and predict prognosis. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Cervical Vestibular Evoked Myogenic Potentials in Idiopathic Intracranial Hypertension
Conclusions: cVEMPs are affected in patients with IIH and the main finding is the absence of the responses. Increased intracranial pressure causing sound transmission changes within the inner ear can affect the saccular afferents and may end up with absent responses on air-conducted cVEMP recordings. To comment on the correlation between the CSF pressure and cVEMP changes, successive cVEMP recordings with longitudinal CSF pressure monitoring seem necessary. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Anesthesia-Associated Periodic Discharges
Conclusions: Generalized periodic patterns are common following the wean of intravenous anesthetics (particularly pentobarbital) and likely represent a transitional encephalopathic state in a subset of patients. Their morphology is distinct and can be differentiated from the reemergence of status epilepticus (if the latter was the indication for anesthetic treatment). Failure to recognize this pattern may lead to prolonged unnecessary treatments if it is mistaken for the emergence of seizure activity. The presence of concomitant systemic infection and associated antibiotic treatment may be risk factors for the developm...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Intracranial EEG Validation of Single-Channel Subgaleal EEG for Seizure Identification
Conclusions: Single-channel SGEEG, placed at or near the vertex, reliably identifies focal and secondarily generalized seizures. These findings demonstrate that the SG space at the cranial vertex may be an appropriate site for long-term ambulatory seizure monitoring. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research