The Prognostic Value of Quantitative EEG in Patients Undergoing Mechanical Thrombectomy for Acute Ischemic Stroke
Conclusions: The quantitative EEG measure of interhemispheric slow relative to fast frequencies power asymmetry correlated with the discharge and 3-month National Institutes of Health Stroke and Modified Rankin Scale scores and provided added value to infarct volume in predicting functional outcome at 3 months. These data support the prognostic value of quantitative EEG in ischemic stroke patients who have undergone mechanical thrombectomy. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Video Ambulatory EEG in Children: A Quality Improvement Study
Conclusions: Video ambulatory EEG may be an effective diagnostic modality among children selected by clinicians and caregivers to undergo long-term EEG monitoring. Given it is effective as well as convenient, accessible, and lower cost than inpatient EEG monitoring, all of which align with our institution's quality goals, we intend to expand our VA-EEG Program. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Creating a New Set of Milestones for the Clinical Neurophysiology Fellowship
Conclusions: The revised Accreditation Council for Graduate Medical Education milestones for CNP fellowship contain important updates that program directors should review against their curricula to identify any gaps in learning. Program leadership should take note of two new Patient Care milestones for telemedicine and intraoperative monitoring. Clinical neurophysiology fellowships are not designed to provide level 4 competency across all milestones. The revised milestones should be viewed within the context of an individual program's goals. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Review Article Source Type: research

Clinical Neurophysiology of Zika Virus Encephalitis
Summary: Zika virus (ZIKV) has been shown to be highly neurotropic; neurologic disorders are a common complication of this infection. Encephalitis—an inflammation of the brain parenchyma associated with neurologic dysfunction—is a rare complication of ZIKV infections. It affects patients from young to elderly ages. Clinical presentation of ZIKV encephalitis may be heterogeneous, including altered mental status (decreased or altered level of consciousness, lethargy, or personality change), seizures, and focal deficits. Complementary diagnostic investigation should include neuroimaging, lumbar puncture, and EEG. Neur...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Clinical Neurophysiology of Zika Virus–Related Disorders of the Peripheral Nervous System in Adults
Summary: During the 2013 to 2016 outbreak in the Pacific and Americas, Zika virus infection resulted not only in febrile and cutaneous manifestations but also in (severe) neurologic complications. These included both central and peripheral nervous system disorders. The most frequent was Guillain–Barré syndrome that typically developed 1 to 2 weeks after the acute infection. Later, other peripheral nervous system syndromes were recognized in association with the viral infection, broadening the spectrum of Zika virus–related peripheral nervous system syndromes. In the current article, the authors review all availabl...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Epilepsy and EEG Abnormalities in Congenital Zika Syndrome
Summary: The congenital Zika syndrome is a new entity of a group of etiologies that can lead to microcephaly and other brain damages during pregnancy, such as toxoplasmosis, rubeola, cytomegalovirus, and herpes simplex. The Zika virus crosses the placental barrier and, predominantly, affects neuronal progenitor cells. This disruptive process results in severe cortical developmental disorder, calcifications, cortical and subcortical atrophies, and malformations of the cerebellum, brain stem, and spinal cord. Children with congenital Zika syndrome have a set of clinical findings, such as cerebral palsy, dysphagia, orthop...
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Clinical Neurophysiology of Zika Virus Infection
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - May 1, 2022 Category: Neurology Tags: Guest Editorial Source Type: research

Sentinel Epileptiform Discharges Activating Two Seizure Networks on Intracranial EEG
Summary: Sentinel epileptiform discharges (SEDs) are epileptiform transients preceding the onset of a focal seizure seen on scalp EEG. Despite their potential localizing value, formal study of SED has been limited. The authors report a patient with MRI-negative focal-onset epilepsy whose seizures on scalp and intracranial EEG were always preceded by SED. Although the location and morphology of the SED was invariable, the seizures after the discharge were of two clearly distinct types, each with different semiology and region of spread on intracranial EEG. This suggests that the SED played a role in activating two disti...
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Case Report Source Type: research

Improving Detection of Hippocampal Epileptiform Activity Using Magnetoencephalography
Conclusions: When grouped by conventional MEG analysis, virtual sensors can be useful to confirm mesial temporal dipoles seen with conventional analysis. Significance: This work may help support the use of MEG for the detection of epileptiform activity in the hippocampus and influence the planning of invasive electrode placement. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Optical Flow Estimation Improves Automated Seizure Detection in Neonatal EEG
Conclusions: This work presents a novel approach to improving automated seizure detection algorithms used during neonatal video EEG monitoring. This artifact detection mechanism can improve the ability of a seizure detector algorithm to distinguish between artifact and true seizure activity. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Neuroimaging Correlates of Lateralized Rhythmic Delta Activity, Lateralized Periodic Discharges, and Generalized Rhythmic Delta Activity on EEG in Critically Ill Patients
Conclusions: Patients with LRDA had a similarly high rate of acute focal abnormalities ipsilateral to the EEG pattern compared with those with LPDs. Patients with GRDA were more likely to have a normal MRI, but the majority of patients with GRDA still had acute focal findings. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Original Research Source Type: research

The Presence and Significance of A-Waves—A Retrospective Review of 679 Patients
Conclusions: A-waves are commonly seen in symptomatic individuals with otherwise normal nerve conduction studies and individuals with various neurologic conditions but are more commonly found in nerves with otherwise abnormal electrophysiological testing. A-waves are most seen in tibial nerves. Multiple A-waves were more commonly seen in demyelinating neuropathy than other conditions. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Original Research Source Type: research

Seizure Risk in Patients Undergoing 30-Day Readmission After Continuous EEG Monitoring
Purpose: The use of continuous electroencephalographic (cEEG) monitoring has improved the understanding of the seizure risk during acute hospitalization. However, the immediate posthospitalization seizure risk in these patients remains unknown. Patients undergoing 30-day readmission after initial cEEG monitoring were analyzed to fill this knowledge gap. Methods: A prospectively maintained cEEG database (January 1, 2015–December 31, 2015) was used to identify adults who underwent a repeat cEEG during their 30-day readmission after cEEG during their index hospitalization (index cEEG). Various demographical, clin...
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Original Research Source Type: research

The Utility of Quantitative EEG in Detecting Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage
Summary: In this review, we discuss the utility of quantitative EEG parameters for the detection of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage in the context of the complex pathophysiology of DCI and the limitations of current diagnostic methods. Because of the multifactorial pathophysiology of DCI, methodologies solely assessing blood vessel narrowing (vasospasm) are insufficient to detect all DCI. Quantitative EEG has facilitated the exploration of EEG as a diagnostic modality of DCI. Multiple quantitative EEG parameters such as alpha power, relative alpha variability, and alpha/delta ra...
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Invited Review Source Type: research

Spectrograms for Seizure Detection in Critically Ill Children
Summary: Electrographic seizures are common in critically ill children and a significant proportion of these seizures are nonconvulsive. There is an association between electrographic seizures and neurophysiological disturbances, worse short- and long-term neurologic outcomes, and mortality in critically ill patients. In this context, timely diagnosis and treatment of electrographic seizures in critically ill children becomes important. However, most institutions lack the resources to support round-the-clock or frequent review of continuous EEG recordings causing significant delays in seizure diagnosis. Given the curre...
Source: Journal of Clinical Neurophysiology - March 1, 2022 Category: Neurology Tags: Invited Review Source Type: research