Status Triphasicus Versus Status Epilepticus?
Summary: Generalized periodic patterns with triphasic wave morphology, long referred to as triphasic waves [TWs], had been associated with metabolic encephalopathies, although other neurologic and systemic causes have since been identified. In a recent classification of periodic patterns, TWs were formally grouped with the generalized periodic discharges, which are often associated with ictal activity. The interpretation of generalized periodic patterns with TWs as nonictal can have significant implications in the management of comatose patients in nonconvulsive status epilepticus. Electrographic characteristics that h...
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

Do Triphasic Waves and Nonconvulsive Status Epilepticus Arise From Similar Mechanisms? A Computational Model
Conclusions: The results of this study add to evidence from other studies calling into question the dichotomy between triphasic waves in TME and GPDs in GNCSE and support the hypothesis that all GPDs, including those arising in TME patients, occur via a common mechanism. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

Can We Distinguish Triphasic Waves From Other Generalized Periodic Discharges? Do We Need to?
Summary: Triphasic waves are intuitively distinctive waveforms that fall under the umbrella of generalized periodic discharges. The ability to distinguish these waveforms consistently could be helpful if a specific underlying pathophysiology could be identified. However, scalp EEG and clinical observation have been limited in their ability to elucidate the underlying cortical physiology that leads to triphasic waves. Evidence from intracranial physiologic data and computational modeling suggest that these and other periodic discharges should be viewed not as strictly ictal nor non-ictal but rather on the spectrum betwe...
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

White Matter Disease—The True Source of Triphasic Waves?
Summary: Triphasic waves are EEG phenomena typically seen in patients with acute encephalopathy and have importance in diagnosis and prognosis in these cases. The underlying metabolic disturbances associated with their incidence have been described previously, but neuroimaging characteristics are not well delineated. There are a few small studies that define neuroimaging results in patients with triphasic waves. This review highlights the most common neuroimaging findings in these patients, including subcortical white matter disease, which itself may be a risk factor for triphasic waves. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

An EEG Voyage in Search of Triphasic Waves—The Sirens and Corsairs on the Encephalopathy/EEG Horizon: A Survey of Triphasic Waves
Summary: Generalized periodic discharges with triphasic wave (TW) morphology, long referred to as TWs, are typical of many toxic, metabolic, infectious, and cerebral structural problems, often in concert. Identifying TWs has been challenging for the electroencephalographer and clinician, as has been their cause, significance, prognosis, and treatment. This review highlights the many different patterns of TWs with commentary on their various causes and etiologies, characteristics, different morbidities, differentiation from nonconvulsive status epilepticus, and their prognosis. The articles in this Journal of Clinical N...
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

Editorial on Triphasic Waves
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - September 1, 2021 Category: Neurology Tags: Guest Editorial Source Type: research

Electromyography and Neuromuscular Disorders: Clinical–Electrodiagnostic–Ultrasound Correlations, Fourth Edition
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Book Review Source Type: research

Perioperative Stroke Detected Using Novel SSEP Analysis
Summary: Using a previously described technique that measures the “velocity” of the upswing of the median nerve SSEP, we identified an ischemic event during a carotid surgery that did not meet traditional alarm criteria. Mechanical thrombectomy successfully removed a thrombus, and the patient experienced a good recovery. Analysis of the SSEP waveform may allow for the detection of events missed with traditional alarm criteria. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Case Report Source Type: research

Effects of Deep Brain Stimulation and Dopaminergic Medication on Excitatory and Inhibitory Spinal Pathways in Parkinson Disease
Conclusions: The present pilot study demonstrates that the recruitment of early inhibition and late facilitation is disrupted in untreated Parkinson disease and that medication and deep brain stimulation may act together to normalize supraspinal drive to the motor neuron pool. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

EEG Synchronization—Parameters in Patients With Subcortical Arteriosclerotic Encephalopathy and Gait Disorder
Conclusions: Changes in EEG synchronization in patients with SAE and gait disorders seem to occur independently of cognitive function. The causal relationship of the changes in EEG synchronization and gait disorders remains to be clarified. The results of this study might point to a decrease in coupling efficiency in these patients, with the increase in synchronization duration as a possible compensatory mechanism. Because a time-efficient signal transmission particularly during gait execution is crucial, reduced efficiency might contribute to an impairment of postural stabilization. The study results might indicate a ...
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

ADHD in University Settings: Predictive Validity of Quantitative EEG Coherence
Conclusions: Suggestions for improving ADHD identification in college populations using quantitative EEG are discussed. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Laser-Evoked Potentials to Pudendal Stimulation in Healthy Subjects: A Pilot Study
Conclusions: This study provides normative data on pudendal LEPs versus hand and foot LEPs. Incorporation of pudendal LEPs into clinical practice could provide a valuable neurophysiological tool for the study of pelvic pain syndromes. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

The Neurophysiological Severity of Carpal Tunnel Syndrome Cannot Be Predicted by Median Nerve Cross-Sectional Area and Wrist-to-Forearm Ratio
Conclusions: The CSA and WFR are satisfactorily reliable in detecting carpal tunnel syndrome, but they cannot be considered as surrogate indicators of electrophysiological severity. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Effect of Compound Muscle Action Potential After Peripheral Nerve Stimulation Normalization on Anesthetic Fade of Intraoperative Transcranial Motor-Evoked Potential
Conclusions: Compound muscle action potential after peripheral nerve stimulation normalization was able to avoid the effect of anesthetic fade. Anesthetic fade was seemed to be caused by a decrease in synaptic transmission at the neuromuscular junction because of propofol accumulation by this result. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Diabetic Neuropathy Influences Control of Spinal Mechanisms
In this study, 48 patients with type 1 diabetes and DSPN were compared with 21 healthy controls. Perception and reflex thresholds were determined and subjects received electrical stimulations on the plantar site of the foot at three stimulation intensities to evoke a nociceptive withdrawal reflex. Electromyogram and EEG were recorded for analysis. Results: Patients with DSPN had higher perception (P (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - July 1, 2021 Category: Neurology Tags: Original Research Source Type: research