Book Identification: A Practical Approach to STEREO EEG
No abstract available (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Book Review Source Type: research

Using CT Perfusion in the Interictal State
Summary: Periodic discharges seen in patients undergoing continuous EEG pose a challenge to physicians in falling into the interictal–ictal continuum and need for appropriate diagnostic and management approach. The authors herein present an 83-year-old male patient with an acute subdural hematoma who developed intermittent right upper and lower extremity weakness with change in mental status post craniotomy and hematoma evacuation. The patient was intubated and sedated with midazolam and propofol and placed on anti-seizure medications to control seizures. He was placed on continuous EEG monitoring and later developed...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Case Report Source Type: research

Ultrasound First for Pediatric Patients in an Electrodiagnostic Laboratory
Conclusions: Using ultrasound first in the electrodiagnostic laboratory in pediatric patients could reduce the number of electrodiagnostic tests needed to arrive at a diagnosis. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Motor Cortex Function in APOE4 Carriers and Noncarriers
Conclusions: The results from this study suggest that motor cortex function, as assessed by transcranial magnetic stimulation measures of excitability and inhibition, and MRS measures of excitatory and inhibitory neurotransmitter are similar in those who possess an apoε4 allele and those who do not. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

In the Kingdom of Triphasic Waves, White Matter Is the Eminence Grise
Conclusions: This is the first series to demonstrate convincingly the presence of TWs in patients with WMD in the absence of commonly cited risk factors. The authors hypothesize that less recognized risk factors of WMD and mild metabolic or infectious abnormalities may be drivers of TWs. With a growing elderly population, the presence of WMD will increase, and treating physicians need to look beyond the common causes of TWs. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Insular Magnetoencephalography Dipole Clusters in Patients With Refractory Focal Epilepsy
Conclusions: Insular MEG dipole clusters identified on surface MEG correlated with interictal spikes in intracranial stereotactic electrode contacts in the insula. The presence of insular MEG dipole clusters, however, does not definitively imply a primary insular onset epilepsy. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Hypnagogic Frontal EEG Bursts in Children: Epileptic or Not?
Purpose: Various EEG patterns emerge in drowsiness. Intermittent bilateral midfrontal slowing (BFS) and hypnogogic frontal predominant sharply contoured waveforms (HFSC), maximal at (Fz, F3-4, and Fp1-2), are often encountered. These do not meet the criteria for epileptiform discharges. The study objective was to determine the clinical significance of BFS and HFSC. Methods: Clinical information of children with BFS (n = 49) and HFSC (n = 99) was compared with control subjects with generalized spike-wave (GSW) discharges (n = 102) and normal EEGs (n = 100). Results: HFSC was present in younger children (me...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

EEG Findings and Releases From Hospital for Patients With Anti-NMDA Receptor Encephalitis
Conclusions: EEGs are frequently abnormal in patients with anti-N-methyl-D-aspartate receptor encephalitis. The lower modified Rankin scale at admission and the absence of some focal epileptiform activity may be associated with shorter hospitalizations. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Expanding Access to Continuous EEG Monitoring in Neonatal Intensive Care Units
Conclusions: Establishment of a remote CEEG program for neonates is feasible, effective at identifying seizures, and improves the quality of care provided to neonates hospitalized at these network hospitals. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Prognostic Significance of Cyclic Seizures in Status Epilepticus
Conclusions: The findings of this study suggest that CS may have a more favorable outcome compared with NCS in patients younger than 75 years. This study is also the first to report the rate of CS among all cases of confirmed SE (38%). Future studies with a larger sample size are needed to further evaluate the difference in outcome between CS and NCS. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

A Standardized Electrode Nomenclature for Stereoelectroencephalography Applications
Conclusions: This standardized naming convention, Standardized Electrode Nomenclature for SEEG Application, provides a simple, concise, reproducible, and informative method for specifying the target(s) and relative position of each SEEG electrode in each patient, allowing for successful sharing of information in both the clinical and research settings. General adoption of this nomenclature could pave the way for improved communication and collaboration between institutions. (Source: Journal of Clinical Neurophysiology)
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Original Research Source Type: research

Cathodal Transcranial Direct Current Stimulation in Refractory Epilepsy: A Noninvasive Neuromodulation Therapy
Summary: Epilepsy is a chronic disease of the brain that affects individuals of all ages and has a worldwide distribution. According to a 2006 World Health Organization report, 50 million people had epilepsy. Approximately 30% of people with epilepsy have refractory disease despite recent therapeutic developments. Consequently, new treatments are necessary. Transcranial direct current stimulation (tDCS) is a noninvasive method for cortical excitability modulation by subthreshold membrane depolarization or hyperpolarization (cathodal stimulation decreases cortical excitability, whereas anodal stimulation increases it), ...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

Neuromodulation in Super-refractory Status Epilepticus
Summary: Status epilepticus (SE) is a severe condition that needs immediate pharmacological treatment to tackle brain damage and related side effects. In approximately 20% of cases, the standard treatment for SE does not control seizures, and the condition evolves to refractory SE. If refractory status epilepticus lasts more than 24 hours despite the use of anesthetic treatment, the condition is redefined as super-refractory SE (srSE). sRSE is a destructive condition, potentially to cause severe brain damage. In this review, we discuss the clinical neuromodulation techniques for controlling srSE when conventional treat...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

Centromedian Nucleus and Epilepsy
Summary: Centromedian thalamic nucleus is an intralaminar nucleus with vast connectivity to cerebral cortex and basal ganglia. It receives afferents from the brain stem through the central tegmental tract and is part of the diffuse thalamic projection system. Because the reticulothalamic system has been related to initiation and propagation of epileptic activity (centroencephalic theory of epilepsy), deep brain stimulation has been proposed to interfere with seizure genesis or propagation. Centromedian thalamic nucleus is a large nucleus laying nearby the anatomical references for stereotaxis and therefore a convenient...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Invited Review Source Type: research

New Horizons in Temporal Lobe Seizure Control
Summary: In patients with mesial temporal lobe epilepsy, high-frequency, low-amplitude electrical stimulation (ES) was applied during 3 weeks through contacts of intracranial electrodes that defined the epileptogenic zone. This subacute ES induced cessation of spontaneous seizures, decreased the number of EEG interictal spikes, caused a 10-fold increase in threshold to induce postdischarges, and showed a profound decrease in regional blood flow of the stimulated area in SPECT studies. Autoradiography analysis of surgical specimens from these patients demonstrated increased expression of benzodiazepine receptors and in ...
Source: Journal of Clinical Neurophysiology - November 1, 2021 Category: Neurology Tags: Invited Review Source Type: research