Intensive Care Medicine Experimental This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Colonic oxygen microbubbles augment systemic oxygenation and CO2 removal in a porcine smoke inhalation model of severe hypoxia
Inhalation injury can lead to pulmonary complications resulting in the development of respiratory distress and severe hypoxia. Respiratory distress is one of the major causes of death in critically ill patient... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 26, 2023 Category: Surgery Authors: Paul A. Mountford, Premila D. Leiphrakpam, Hannah R. Weber, Andrea McCain, Robert M. Scribner, Robert T. Scribner, Ernesto M. Duarte, Jie Chen, Dragana Noe, Mark A. Borden and Keely L. Buesing Tags: Research Articles Source Type: research

Could daily changes in respiratory microbiota help predicting early Staphylococcus aureus ventilator-associated pneumonia?
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 23, 2023 Category: Surgery Authors: Sylvain Meyer, Nadia Ga ïa, Vladimir Lazarevic, Jacques Schrenzel, Bruno François and Olivier Barraud Tags: Letters to the Editor Source Type: research

Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill, invasively mechanically ventilated COVID-19 patients
Vilobelimab, a complement 5a (C5a)-specific monoclonal antibody, reduced mortality in critically ill COVID-19 patients in a phase 3 multicentre, randomized, double-blind, placebo-controlled study. As part of t... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 19, 2023 Category: Surgery Authors: Endry H. T. Lim, Alexander P. J. Vlaar, Sanne de Bruin, Simon R ückinger, Claus Thielert, Maria Habel, Renfeng Guo, Bruce P. Burnett, James Dickinson, Matthijs C. Brouwer, Niels C. Riedemann and Diederik van de Beek Tags: Research Articles Source Type: research

The impact of intravenous dodecafluoropentane on a murine model of acute lung injury
Intravenous oxygen therapeutics present an appealing option for improving arterial oxygenation in patients with acute hypoxemic respiratory failure, while limiting iatrogenic injury from conventional respirato... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 16, 2023 Category: Surgery Authors: Jarrod M. Mosier, Saad Sammani, Carrie Kempf, Evan Unger and Joe G. N. Garcia Tags: Research Articles Source Type: research

Reduced anticoagulation strategy is associated with a lower incidence of intracerebral hemorrhage in COVID-19 patients on extracorporeal membrane oxygenation
Optimal anticoagulation strategies for COVID-19 patients with the acute respiratory distress syndrome (ARDS) on venovenous extracorporeal membrane oxygenation (VV ECMO) remain uncertain. A higher incidence of ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 12, 2023 Category: Surgery Authors: Daniel A. Hofmaenner, David Furfaro, Lennart C. Wild, Pedro David Wendel-Garcia, Elias Baedorf Kassis, Ameeka Pannu, Tobias Welte, Rolf Erlebach, Klaus Stahl, Edward Wilson Grandin, Christian Putensen, Reto A. Schuepbach, Shahzad Shaefi, Sascha David, Ben Tags: Research Articles Source Type: research

In an endotoxaemic model, antibiotic clearance can be affected by different central venous catheter positions, during renal replacement therapy
In intensive care, different central venous catheters (CVC) are often used for infusion of drugs. If a patient is treated with continuous renal replacement therapy (CRRT) a second catheter, a central venous di... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 9, 2023 Category: Surgery Authors: Anna Bandert, Mikl ós Lipcsey, Robert Frithiof, Anders Larsson and David Smekal Tags: Research Articles Source Type: research

A model of porcine polymicrobial septic shock
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Mortality of patients with sepsis is high and largely unchanged throughout the past decades. Animal models ha... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - June 2, 2023 Category: Surgery Authors: Finnja Marie Zurek-Leffers, Florian Lehmann, Laura Brabenec, Sebastian Kintrup, Katharina E. M. Hellenthal, Kira Mersjann, Felicia Kneifel, Michael Hessler, Philip-Helge Arnemann, Tim-Gerald Kampmeier, Christian Ertmer, Patrick Kellner and Nana-Maria Wagn Tags: Research Articles Source Type: research

Temporal relationship between vasopressor and sedative administration and cerebrovascular response in traumatic brain injury: a time-series analysis
Although vasopressor and sedative agents are commonly used within the intensive care unit to mediate systemic and cerebral physiology, the full impact such agents have on cerebrovascular reactivity remains unc... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 29, 2023 Category: Surgery Authors: Logan Froese, Alwyn Gomez, Amanjyot Singh Sainbhi, Nuray Vakitbilir, Izabella Marquez, Fiorella Amenta, Kevin Y. Stein and Frederick A. Zeiler Tags: Research Articles Source Type: research

False-positive Legionella pneumophila antibodies in COVID-19 patients
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 26, 2023 Category: Surgery Authors: Shu-hua He, Shan Li and Li Weng Tags: Letters to the Editor Source Type: research

Is mechanical power an under-recognised entity within the preterm lung?
Mechanical power is a major contributor to lung injury and mortality in adults receiving mechanical ventilation. Recent advances in our understanding of mechanical power have allowed the different mechanical c... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 22, 2023 Category: Surgery Authors: David G. Tingay, Hannah Naidu, Hamish D. Tingay, Prue M. Pereira-Fantini, Martin C. J. Kneyber and Tobias Becher Tags: Hypothesis Source Type: research

An experimental porcine model of invasive candidiasis
Invasive candidiasis (IC) is a severe and often fatal fungal infection that affects critically ill patients. The development of animal models that mimic human disease is essential for advancing our understandi... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 15, 2023 Category: Surgery Authors: Anders Krifors, Anders Lignell, Mikl ós Lipcsey, Jan Sjölin and Markus Castegren Tags: Methodologies Source Type: research

Research priorities for therapeutic plasma exchange in critically ill patients
Therapeutic plasma exchange (TPE) is a therapeutic intervention that separates plasma from blood cells to remove pathological factors or to replenish deficient factors. The use of TPE is increasing over the la... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 8, 2023 Category: Surgery Authors: Sascha David, Lene Russell, Pedro Castro, Andry van de Louw, Lara Zafrani, Tasneem Pirani, Nathan D. Nielsen, Eric Mariotte, Bruno L. Ferreyro, Jan T. Kielstein, Luca Montini, Anne C. Brignier, Matthias Kochanek, Joan Cid, Chiara Robba, Ignacio Martin-Loe Tags: Reviews Source Type: research

Furosemide exacerbated the impairment of renal function, oxygenation and medullary damage in a rat model of renal ischemia/reperfusion induced AKI
Perioperative acute kidney injury (AKI) caused by ischemia –reperfusion (IR) is a significant contributor to mortality and morbidity after major surgery. Furosemide is commonly used in postoperative patients to... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - May 1, 2023 Category: Surgery Authors: Olcay Dilken, Can Ince, Aysegul Kapucu, Paul M. Heeman and B ülent Ergin Tags: Research Articles Source Type: research

Comparison of cardiac index measurements in intensive care patients using continuous wave vs. pulsed wave echo-Doppler compared to pulse contour cardiac output
Cardiac index (CI) assessments are commonly used in critical care to define shock aetiology and guide resuscitation. Echocardiographic assessment is non-invasive and has high levels of agreement with thermodil... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 28, 2023 Category: Surgery Authors: Prashant Parulekar, James Powys-Lybbe, Paul Bassett, Seb Roques, Mark Snazelle, Gemma Millen and Tim Harris Tags: Research Articles Source Type: research

Effect of low-to-moderate hyperoxia on lung injury in preclinical animal models: a systematic review and meta-analysis
Extensive animal investigation informed clinical practice regarding the harmful effects of high fractional inspired oxygen concentrations (FiO2s  > 0.60). Since questions persist whether lower but still supraphysi... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - April 24, 2023 Category: Surgery Authors: Samuel Minkove, Rhea Dhamapurkar, Xizhong Cui, Yan Li, Junfeng Sun, Diane Cooper, Peter Q. Eichacker and Parizad Torabi-Parizi Tags: Reviews Source Type: research