Intensive Care Medicine Experimental This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Computed tomographic assessment of lung aeration at different positive end-expiratory pressures in a porcine model of intra-abdominal hypertension and lung injury
Intra-abdominal hypertension (IAH) is common in critically ill patients and is associated with increased morbidity and mortality. High positive end-expiratory pressures (PEEP) can reverse lung volume and oxyge... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - October 4, 2021 Category: Surgery Authors: Adrian Regli, Siavash Ahmadi-Noorbakhsh, Gabrielle Christine Musk, David Joseph Reese, Peter Herrmann, Martin Joseph Firth and J. Jane Pillow Tags: Research Articles Source Type: research

ESICM LIVES 2021: Part 1
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 29, 2021 Category: Surgery Tags: Meeting abstracts Source Type: research

Evaluation of a simultaneous adsorption device for cytokines and platelet –neutrophil complexes in vitro and in a rabbit acute lung injury model
Platelet –neutrophil complexes (PNCs) readily migrate into tissues and induce tissue damage via cytokine or other pathogenic factors release. These actions are involved in onset and progression of acute respira... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 27, 2021 Category: Surgery Authors: Yumiko Sekiya, Kaoru Shimada, Hiroshi Takahashi, Chisa Kuga, Shunsuke Komachi, Keishi Miwa and Toru Kotani Tags: Research Articles Source Type: research

A randomised controlled trial of succinylated gelatin (4%) fluid on urinary acute kidney injury biomarkers in cardiac surgical patients
Fluid resuscitation is frequently required for cardiac surgical patients admitted to the intensive care unit. The ideal fluid of choice in regard to efficacy and safety remains uncertain. Compared with crystal... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 22, 2021 Category: Surgery Authors: Lisa Smart, Corrin Boyd, Edward Litton, Warren Pavey, Philip Vlaskovsky, Umar Ali, Trevor Mori, Anne Barden and Kwok Ming Ho Tags: Research Articles Source Type: research

Novel method of transpulmonary pressure measurement with an air-filled esophageal catheter
There is a strong rationale for proposing transpulmonary pressure-guided protective ventilation in acute respiratory distress syndrome. The reference esophageal balloon catheter method requires complex in vivo... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 17, 2021 Category: Surgery Authors: Paul Bernard Massion, Julien Berg, Nicolas Samalea Suarez, Gilles Parzibut, Bernard Lambermont, Didier Ledoux and Pierre Pascal Massion Tags: Methodologies Source Type: research

Validation of a novel system to assess end-expiratory lung volume and alveolar recruitment in an ARDS model
Personalizing mechanical ventilation requires the development of reliable bedside monitoring techniques. The multiple-breaths nitrogen washin –washout (MBNW) technique is currently available to measure end-expi... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 10, 2021 Category: Surgery Authors: Laurent Bitker, Nadja Cristinne Carvalho, Sascha Reidt, Christoph Schranz, Dominik Novotni, Maciej Orkisz, Eduardo Davila Serrano, Jean-Pierre Revelly and Jean-Christophe Richard Tags: Research Articles Source Type: research

Progranulin signaling in sepsis, community-acquired bacterial pneumonia and COVID-19: a comparative, observational study
Progranulin is a widely expressed pleiotropic growth factor with a central regulatory effect during the early immune response in sepsis. Progranulin signaling has not been systematically studied and compared b... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 3, 2021 Category: Surgery Authors: Florian Brandes, Melanie Borrmann, Dominik Buschmann, Agnes S. Meidert, Marlene Reithmair, Markus Langkamp, Lutz Pridzun, Benedikt Kirchner, Jean-No ël Billaud, Nirav M. Amin, Joseph C. Pearson, Matthias Klein, Daniela Hauer, Clarissa Gevargez Zoubalan, Tags: Research Articles Source Type: research

Killer immunoglobulin-like receptor 2DS5 is associated with recovery from coronavirus disease 2019
Despite numerous advances in the identification of risk factors for the development of severe coronavirus disease 2019 (COVID-19), factors that promote recovery from COVID-19 remain unknown. Natural killer (NK... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - September 3, 2021 Category: Surgery Authors: Vadim Lesan, Moritz Bewarder, Carlos Metz, Andr é Becker, Sebastian Mang, Evi Regitz, Lorenz Thurner, Frank Neumann, Igor Kos, Konstantinos Christofyllakis, Guy Danziger, Stephan Stilgenbauer, Robert Bals, Philipp M. Lepper, Dominic Kaddu-Mulindwa and To Tags: Research Articles Source Type: research

Interstitial washdown and vascular albumin refill during fluid infusion: novel kinetic analysis from three clinical trials
Increased capillary filtration may paradoxically accelerate vascular refill of both fluid and albumin from the interstitial space, which is claimed to be edema-preventing. We characterized this proposed mechan... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - August 27, 2021 Category: Surgery Authors: Robert G. Hahn and Randal O. Dull Tags: Research Articles Source Type: research

Inflammatory markers assessment in an animal model of intracranial hypertension: a randomized trial
Intracranial hypertension (ICH) is a common final pathway of most neurosurgical pathologies and leads to poor prognosis if not detected and treated properly. Inflammatory markers have been assessed in clinical... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - August 23, 2021 Category: Surgery Authors: Marcelo Prudente do Esp írito Santo, Caroline Silvério Faria, Davi Jorge Fontoura Solla, Leonardo Zumerkorn Pipek, Alessandro Rodrigo Belon, Brasil Ping Jeng, Almir Ferreira de Andrade, Manoel Jacobsen Teixeira and Wellingson Silva Paiva Tags: Research Articles Source Type: research

Complement factor D is linked to platelet activation in human and rodent sepsis
The complement factor D (CFD) exerts a regulatory role during infection. However, its physiological function in coagulopathy and its impact on the course of an infection remains unclear. (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - August 16, 2021 Category: Surgery Authors: O. Sommerfeld, K. Dahlke, M. Sossdorf, R. A. Claus, A. Scherag, M. Bauer and F. Bloos Tags: Research Articles Source Type: research

Rapid screening of critically ill patients for low plasma vitamin C concentrations using a point-of-care oxidation –reduction potential measurement
Hypovitaminosis C and vitamin C deficiency are common in critically ill patients and associated with organ dysfunction. Low vitamin C status often goes unnoticed because determination is challenging. The stati... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - August 9, 2021 Category: Surgery Authors: Sander Rozemeijer, Bob Smit, Paul W. G. Elbers, Armand R. J. Girbes, Heleen M. Oudemans-van Straaten and Angelique M. E. de Man Tags: Research Articles Source Type: research

Flow-dependent regulation of endothelial Tie2 by GATA3 in vivo
Reduced endothelial Tie2 expression occurs in diverse experimental models of critical illness, and experimental Tie2 suppression is sufficient to increase spontaneous vascular permeability. Looking for a commo... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - August 2, 2021 Category: Surgery Authors: Temitayo O. Idowu, Valerie Etzrodt, Thorben Pape, Joerg Heineke, Klaus Stahl, Hermann Haller and Sascha David Tags: Research Articles Source Type: research

Effect of positive end-expiratory pressure on additional passive ventilation generated by CPR compressions in a porcine model
Compressions given during cardiopulmonary resuscitation generate small, ineffective passive ventilations through oscillating waves. Positive end-expiratory pressure increases the volume of these passive ventil... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - July 26, 2021 Category: Surgery Authors: Yosef Levenbrown, Md Jobayer Hossain, James P. Keith, Katlyn Burr, Anne Hesek and Thomas H. Shaffer Tags: Research Articles Source Type: research

Mortality of septic shock patients is associated with impaired mitochondrial oxidative coupling efficiency in lymphocytes: a prospective cohort study
Septic shock is a life-threatening condition that challenges immune cells to reprogram their mitochondrial metabolism towards to increase ATP synthesis for building an appropriate immunity. This could print me... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - July 24, 2021 Category: Surgery Authors: Wagner Luis Nedel, Afonso Kopczynski, Marcelo Salimen Rodolphi, Nathan Ryzewski Strogulski, Marco De Bastiani, Tiago Hermes Maeso Montes, Jose Abruzzi Jr, Antonio Galina, Tamas L. Horvath and Luis Valmor Portela Tags: Research Articles Source Type: research