Intensive Care Medicine Experimental This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Mesenchymal stem cells-based therapies for severe ARDS with ECMO: a review
Acute respiratory distress syndrome (ARDS) is the primary cause of respiratory failure in critically ill patients. Despite remarkable therapeutic advances in recent years, ARDS remains a life-threatening clini... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - February 9, 2024 Category: Surgery Authors: Jing-Ke Cao, Xiao-Yang Hong, Zhi-Chun Feng and Qiu-Ping Li Tags: Reviews Source Type: research

Positive end-expiratory pressure limits inspiratory effort through modulation of the effort-to-drive ratio: an experimental crossover study
How assisted spontaneous breathing should be used during acute respiratory distress syndrome is questioned. Recent evidence suggests that high positive end-expiratory pressure (PEEP) may limit the risk of pati... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - February 5, 2024 Category: Surgery Authors: Hannes Widing, Mariangela Pellegrini, Elena Chiodaroli, Per Persson, Katarina Hall én and Gaetano Perchiazzi Tags: Research Articles Source Type: research

Validation of a low-cost continuous renal replacement therapy dialysate fluid controller for experimental purposes
Continuous renal replacement therapy (CRRT) support is crucial for critically ill patients and it is underexplored in specific situations. Experimental CRRT offers a means to gain insights into these scenarios... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - February 2, 2024 Category: Surgery Authors: Yuri de Albuquerque Pessoa dos Santos, Viviane Flor Park, Luis Carlos Maia Cardozo Junior, Bruno Adler Maccagnan Pinheiro Besen, Pedro Vitale Mendes and Marcelo Park Tags: Research Articles Source Type: research

Understanding the pathophysiology of acute critical illness: translational lessons from zebrafish models
The models used to investigate the pathophysiological mechanisms of acute critical illness are not limited to mammalian species. The zebrafish (Danio rerio) is a popular model organism for studying diseases due t... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 31, 2024 Category: Surgery Authors: Kensuke Fujii, Kazuma Yamakawa, Yuriko Takeda, Natsuko Okuda, Akira Takasu and Fumihito Ono Tags: Reviews Source Type: research

Recombinant antithrombin attenuates acute kidney injury associated with rhabdomyolysis: an in vivo animal study
Rhabdomyolysis is characterized by the destruction and necrosis of skeletal muscle tissue, resulting in acute kidney injury (AKI). Recombinant antithrombin (rAT) has DNA repair and vascular endothelial-protect... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 29, 2024 Category: Surgery Authors: Tomotaka Miura, Tomoki Okuda, Kodai Suzuki, Hideshi Okada, Hiroyuki Tomita, Chihiro Takada, Kosuke Mori, Hirotaka Asano, Soichiro Kano, Yugo Wakayama, Yohei Fukuda, Hirotsugu Fukuda, Ayane Nishio, Yuki Kawasaki, Ayumi Kuroda, Keiko Suzuki & hellip; Tags: Research Articles Source Type: research

Estimation of normal lung weight index in healthy female domestic pigs
Lung weight is an important study endpoint to assess lung edema in porcine experiments on acute respiratory distress syndrome and ventilatory induced lung injury. Evidence on the relationship between lung –body... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 26, 2024 Category: Surgery Authors: Antonio Fioccola, Rosmery Valentina Nicolardi, Tommaso Pozzi, Isabella Fratti, Federica Romitti, Francesca Collino, Verena Reupke, Gianluigi Li Bassi, Alessandro Protti, Alessandro Santini, Massimo Cressoni, Mattia Busana, Onnen Moerer, Luigi Camporota an Tags: Methodologies Source Type: research

Validation of an alternative technique for RQ estimation in anesthetized pigs
Respiratory quotient (RQ) is an important variable when assessing metabolic status in intensive care patients. However, analysis of RQ requires cumbersome technical equipment. The aim of the current study was ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 25, 2024 Category: Surgery Authors: Jacob Karlsson, Anders Svedmyr, Mats Wallin, Magnus Hallb äck and Per-Arne Lönnqvist Tags: Research Articles Source Type: research

Current clinical practice in using adjunctive extracorporeal blood purification in sepsis and septic shock: results from the ESICM “EXPLORATION” survey
Despite a lack of clear evidence extracorporeal blood purification (EBP) is increasingly used as an adjunctive treatment in septic shock based on its biological plausibility. However, current state of praxis a... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 19, 2024 Category: Surgery Authors: Klaus Stahl, Christian Bode, Benjamin Seeliger, Pedro David Wendel-Garcia and Sascha David Tags: Research Articles Source Type: research

Estimating the change in pleural pressure using the change in central venous pressure in various clinical scenarios: a pig model study
We have previously reported a simple correction method for estimating pleural pressure (Ppl) using central venous pressure (CVP). However, it remains unclear whether this method is applicable to patients with ... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 15, 2024 Category: Surgery Authors: Miyako Kyogoku, Soichi Mizuguchi, Taku Miyasho, Yusuke Endo, Yu Inata, Kazuya Tachibana, Yuji Fujino, Kazuto Yamashita and Muneyuki Takeuchi Tags: Research Articles Source Type: research

Immunophenotyping patients with sepsis and underlying haematological malignancy reveals defects in monocyte and lymphocyte function
(Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 11, 2024 Category: Surgery Authors: Timothy Arthur Chandos Snow, Aimee Serisier, David Brealey, Mervyn Singer and Nishkantha Arulkumaran Tags: Letters to the Editor Source Type: research

Doxycycline reduces liver and kidney injuries in a rat hemorrhagic shock model
This study aimed to evaluate whether doxycycline (DOX) protects cardiovascular, kidney,... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 9, 2024 Category: Surgery Authors: Regina Sordi, Luana Bojko, Filipe R. M. B. Oliveira, Thiele Osvaldt Rosales, Camila Fernandes Souza, Lucas Wenceslau Moreno, Gustavo Ferreira Alves, Jos é Carlos Rebuglio Vellosa, Daniel Fernandes and Jose Rosa Gomes Tags: Research Articles Source Type: research

Mastering the brain in critical conditions: an update
Acute brain injuries, such as traumatic brain injury and ischemic and hemorragic stroke, are a leading cause of death and disability worldwide. While characterized by clearly distict primary events —vascular da... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - January 5, 2024 Category: Surgery Authors: Chiara Robba, Elisa R. Zanier, Carmen Lopez Soto, Soojin Park, Romain Sonneville, Raimund Helbolk, Aarti Sarwal, Virginia F. J. Newcombe, Mathieu van der Jagt, Jan Gunst, Tobias Gauss, Samy Figueiredo, Jacques Duranteau, Markus B. Skrifvars, Carolina Iaqu Tags: Research Articles Source Type: research

Metabolic disturbances potentially attributable to clogging during continuous renal replacement therapy
Clogging is characterized by a progressive impairment of transmembrane patency in renal replacement devices and occurs due to obstruction of pores by unknown molecules. If citrate-based anti-coagulation is use... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - December 21, 2023 Category: Surgery Authors: Mattia M. M üller, Larina Caspar, Onur Sazpinar, Daniel A. Hofmaenner, Rolf Erlebach, Rea Andermatt, Christoph C. Ganter, Reto A. Schuepbach, Pedro D. Wendel-Garcia and Sascha David Tags: Research Articles Source Type: research

Capillary leak and endothelial permeability in critically ill patients: a current overview
Capillary leak syndrome (CLS) represents a phenotype of increased fluid extravasation, resulting in intravascular hypovolemia, extravascular edema formation and ultimately hypoperfusion. While endothelial perm... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - December 20, 2023 Category: Surgery Authors: Babak Saravi, Ulrich Goebel, Lars O. Hassenzahl, Christian Jung, Sascha David, Aarne Feldheiser, Matthias Stopfkuchen-Evans and Jakob Wollborn Tags: Reviews Source Type: research

A model of hemodialysis after acute kidney injury in rats
Acute kidney injury (AKI) is frequent among critically ill patients. Renal replacement therapy (RRT) is often required to deal with severe complications of AKI. This technique is however associated with side e... (Source: Intensive Care Medicine Experimental)
Source: Intensive Care Medicine Experimental - December 20, 2023 Category: Surgery Authors: J. Mallet, P.-A. Billiet, M. Scarton, N. Benichou, M. Bobot, K. Chaibi, A. Hertig, J. Hadchouel, D. Dreyfuss, S. Gaudry and S. Placier Tags: Research Articles Source Type: research