Effects of ventilatory bundles on patient outcomes among ICU patients: A systematic review and meta-analysis
Patients on mechanical ventilation (MV) are a vulnerable group because of their serious disease conditions, and ventilator-associated pneumonia (VAP) remains one of the most common infections in intensive care units (ICUs).1 VAP has serious consequences, including increases morbidity, mortality, the length of ICU stay, duration of MV, and financial burdens on healthcare systems.2 –4 However, it is important to note that VAP is a preventable infection. Studies have demonstrated that patients who develop VAP stay longer in the ICU (15.7 ± 9.1 days) than those without VAP (4.9 ± 4.9 days),5 with a mortality rate of 32...
Source: Heart and Lung - October 13, 2023 Category: Intensive Care Authors: Dejina Thapa, Sek Ying Chair, Mei Sin Chong, Rishi Ram Poudel, Tenaw Gualu Melesse, Kai Chow Choi, Hon Lon Tam Source Type: research

All Else Being Equal: Examining Treatment Bias and Stereotypes Based on Patient Ethnicity and Socioeconomic Status With In-Hospital Cardiac Arrest Clinical Vignettes
Treating patients equally without the consideration of sociodemographic factors (e.g., ethnicity, gender) is a quality-of-care indicator.1 Equal care is also a legal right in many countries. For example, the Swedish Health and Medical Services Act stipulates that good care should be given to the entire population on equal terms.2 (Source: Heart and Lung)
Source: Heart and Lung - October 12, 2023 Category: Intensive Care Authors: Jens Agerstr öm, Cecilia Andréll, Anders Bremer, Anna Strömberg, Kristofer Årestedt, Johan Israelsson Source Type: research

High level of psychosocial adjustment in patients on ongoing ventricular assist device support in the years one to three after VAD implantation —A national multi-center Study
Advanced heart failure therapies such as durable ventricular assist device (VAD) support can offer improved survival and increased quality of life1 when medical therapies are exhausted. In turn, VAD therapy requires psychosocial adjustment for those affected. As VAD implantation has become an established treatment strategy, 2 a shift in focus to psychosocial factors is important and should capture concepts like psychosocial adjustment consisting of perceived social support, anxiety, depression, and quality of life. (Source: Heart and Lung)
Source: Heart and Lung - October 12, 2023 Category: Intensive Care Authors: Hannah Spielmann, Wolfgang Albert, Sandra Semmig-K önze, Volker Lauenroth, Christine Spitz-Köberich, Paulina Staus, Katharina Tigges-Limmer, Christiane Kugler, SELMA Study Group Source Type: research

Effects of Antihypertensive Agents on the Clinical Outcome of Hospitalized COVID-19 Patients Concomitant with Hypertension: A Systematic Review and Meta-Analysis
Given the ongoing COVID-19 pandemic, it is crucial to prioritize the management of underlying diseases in infected patients, with hypertension being one of the most common conditions. However, there lies a complicated correlation between antihypertensive agents and COVID-19 infection. (Source: Heart and Lung)
Source: Heart and Lung - October 10, 2023 Category: Intensive Care Authors: Jinfeng Liu, Liang Huang, Wei Wei, Yingtao Bai, En Chang, Yanen Leng Source Type: research

Unraveling the link between dietary factors and cardiovascular metabolic diseases: Insights from a two-sample Mendelian Randomization investigation
Dietary nutrition plays a dual role, serving as a vital energy source and a substantial modifiable risk factor. Unhealthy eating habits can worsen the burden of non-communicable diseases. Extensive research underscores the profound impact of dietary nutrition on the emergence of cardiovascular metabolic diseases, encompassing conditions like coronary artery disease (CAD), heart failure (HF), ischemic stroke (IS), and type 2 diabetes (T2DM).1 However, research findings are contradictory, as some studies demonstrate that dietary nutritional factors increase the risk of individuals developing diseases,2 while others show the ...
Source: Heart and Lung - October 10, 2023 Category: Intensive Care Authors: Yue-yue Niu, Aikeremu Aierken, Ling Feng Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - October 8, 2023 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - October 8, 2023 Category: Intensive Care Source Type: research

Which Components of The International Classification of Functioning, Disability and Health (ICF) are Covered by Cardiac Rehabilitation Assessment Tools among Individuals with Heart Failure?
According to data from the World Health Organization (WHO), it was estimated that 17.9 million individuals died of cardiovascular disease(s) in 2019, with mortality concentrated in low- and middle-income countries.1 Heart failure (HF) remains one of the main causes of hospitalization and contributes to cardiac, pulmonary, and skeletal abnormalities that lead to exercise intolerance, reduced functional capacity and quality of life, and increased mortality.2,3 Cardiac rehabilitation (CR) positively affects outcomes in patients with HF. (Source: Heart and Lung)
Source: Heart and Lung - October 6, 2023 Category: Intensive Care Authors: Eriadina Alves Lima, Gezabell Rodrigues, Beatriz Carneiro Mota, Shamyr Sulyvan Castro, Rafael Barreto Mesquita, Camila Ferreira Leite Source Type: research

Effects of a Rapid Response Team on Patient Outcomes: A Systematic Review
It was estimated that over 290,000 in-hospital cardiac arrests occur annually in the United States. 1 Patients who experience clinical deterioration exhibit abnormal physiological vital signs for 1 to 4 hours (such as altered heart rate, respiratory rate, blood pressure, and consciousness level) before cardiac arrest or death occurs. 2 Early detection of alterations in physiological vital signs can help identify people in the early stages of clinical deterioration or at risk of cardiopulmonary arrest and provide prompt intervention. (Source: Heart and Lung)
Source: Heart and Lung - September 27, 2023 Category: Intensive Care Authors: Qiuxia Zhang, Khuan Lee, Zawiah Mansor, Iskasymar Ismail, Yi Guo, Qiao Xiao, Poh Ying Lim Source Type: research

Sedation and analgesia strategies for non-invasive mechanical ventilation: A systematic review and meta-analysis
In patients with acute or chronic respiratory failure, noninvasive mechanical ventilation (NIV) can effectively relieve dyspnea and minimize respiratory muscle fatigue. It is commonly used to treat individuals with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) and acute cardiogenic pulmonary edema.1,2 Compared with invasive mechanical ventilation, NIV reduces patients ’ suffering and the occurrence of ventilator-associated pneumonia.3,4 Furthermore, according to the European Respiratory Society/American Thoracic Society (ERS/ATS) clinical practice recommendations, NIV should be the first line of tr...
Source: Heart and Lung - September 26, 2023 Category: Intensive Care Authors: Baolu Yang, Leyi Gao, Zhaohui Tong Source Type: research

Response to letter to the editor “plasma biomarkers and delirium in critically ill patients after cardiac surgery: A prospective observational cohort study”
We thank Ahmed et  al.1 for their interest and valuable comments on our observational study2 and the opportunity to reply. (Source: Heart and Lung)
Source: Heart and Lung - September 26, 2023 Category: Intensive Care Authors: Li-Jing Su, Rong-Fang Hu Tags: Letter to the editor Source Type: research

Serum proteomic analysis in esophagectomy patients with postoperative delirium: A case-control study
Delirium, a type of an acute brain failure, is characterized by fluctuation in mental status, inattention, altered level of consciousness, and disorganized thinking. Postoperative delirium is highly prevalent, with rates ranging from 15-80%.1,2 Prior studies have found postoperative delirium rates as high as 50% among both cardiac and major noncardiac thoracic surgery patients.3 –7 Unfortunately, effective pharmacological interventions to treat or prevent delirium are not available, likely due to our limited understanding of delirium pathophysiology. (Source: Heart and Lung)
Source: Heart and Lung - September 23, 2023 Category: Intensive Care Authors: Sikandar H. Khan, Anthony J. Perkins, Samreen Jawaid, Sophia Wang, Heidi Lindroth, Rebecca E. Schmitt, Jason Doles, Jason D. True, Sujuan Gao, Gideon A. Caplan, Homer L. Twigg, Kenneth Kesler, Babar A. Khan Source Type: research

Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis
Asthma, a heterogeneous respiratory disease, is characterized by chronic airway inflammation involving various cellular components such as eosinophils, mast cells, and neutrophils.1 Typical clinical symptoms consist of wheezing, shortness of breath, chest constriction, and coughing. This chronic respiratory disorder is characterized by reversible airway restriction and bronchial hyperreactivity.2,3 Asthma has emerged as one of the most prevalent noncommunicable chronic respiratory diseases affecting children, and its prevalence is rising consistently. (Source: Heart and Lung)
Source: Heart and Lung - September 21, 2023 Category: Intensive Care Authors: Hua Li, Tao Dong, Jinling Luan Source Type: research

The Psychometric Properties of the Chinese version of the Interoceptive Awareness Questionnaire (IAQ) among PATIENTS WITH Cardiovascular Disease
Interoception refers to the perception of changes within intenal body.1 Recently, a new explanation of interoception has been suggested, the processes including biological sensation, integrates, interprets, and signal-regulated from within itself.2 Interoception includes three dimensions, such as, interoceptive awareness (referring to a person's belief and awareness of their internal perception ability), accuracy (the performance and reliability of objective measures of internal detection, i. e., heartbeats), and metacognitive dimension (accurate perception on one's own interoceptive behavior) . (Source: Heart and Lung)
Source: Heart and Lung - September 20, 2023 Category: Intensive Care Authors: Liu Huang, Mengtao Song, Ling Wang, Qiran Zhang, Xiao Liu, Chunfeng Cai Source Type: research

Cardiac Rehabilitation Phase II Outcomes Prior to and During COVID
The COVID  pandemic limited access to many Cardiac Rehabilitation (CR) outpatient programs. (Source: Heart and Lung)
Source: Heart and Lung - September 16, 2023 Category: Intensive Care Authors: Harrison Krebs, Kimberly Crutcher, Yan Su, Marilyn A. Prasun Source Type: research