The development of a patient reported outcome measure for fatigue and breathlessness for patients with chronic heart failure (OxFAB)
Chronic heart failure (CHF) is a disabling disease with progressive symptomatic reduced physical activity, the increasing need for hospitalization and support for end of life.1 There are over 26 million people worldwide with CHF.2 CHF can be subdivided into HF with reduced ejection fraction (HFrEF) and HF with preserved ejection fraction (HFpEF). These definitions and parameters are outlined in recent European guidelines3 with HFrEF defined as an ejection fraction (Source: Heart and Lung)
Source: Heart and Lung - December 6, 2022 Category: Intensive Care Authors: Helen Walthall, Louise H. Strickland, Crispin Jenkinson Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - December 3, 2022 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - December 3, 2022 Category: Intensive Care Source Type: research

Combining exercise, protein supplementation and electric stimulation to mitigate muscle wasting and improve outcomes for survivors of critical illness —The ExPrES study
Older patients who suffer from critical illness, particularly those requiring mechanical ventilation (MV), are at high risk for skeletal muscle wasting and loss of physical function from prolonged bed rest. This debilitated state can further perpetuate a prolonged Intensive Care Unit (ICU) stay resulting in increased mortality. The mechanisms for this muscle wasting are multifactorial and include endotoxin-mediated inflammation, nutritional inadequacy and altered substrate metabolism.1-5 Efforts at rehabilitating older, critically ill patients during an ICU admission vary from passive mobility and range of motion exercises...
Source: Heart and Lung - December 3, 2022 Category: Intensive Care Authors: Avelino C. Verceles, Monica Serra, Derik Davis, Gad Alon, Chris L Wells, Elizabeth Parker, John Sorkin, Waqas Bhatti, Michael L. Terrin Source Type: research

Comment on “Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia”
I have read with great interest the manuscript titled “Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia” by Okan S et al 1 and would like to commend them for their brilliant efforts. However, there are a few additional points that I would like to highlight, and which would have enhanced the quality of this study. (Source: Heart and Lung)
Source: Heart and Lung - November 30, 2022 Category: Intensive Care Authors: Samar Sajid Source Type: research

Letter to the Editor: “The effect of cold application on pain in patients with chest tubes before deep breathing and coughing exercises: A randomized controlled study”
Letter (Source: Heart and Lung)
Source: Heart and Lung - November 29, 2022 Category: Intensive Care Authors: Samar Sajid Tags: Letter to the editor Source Type: research

Exertional dyspnea responses to the Dyspnea Challenge in heart failure: Comparison to chronic obstructive pulmonary disease
The Dyspnea Challenge is a clinical-based measure of exertional dyspnea. Advantages over other dyspnea-specific field-based exercise tests are that it is short, requires limited space and no complex equipment, and involves walking uphill, a common precipitator of exertional dyspnea. Among individuals with chronic obstructive lung disease (COPD), the test is reliable,1 valid,1 and sensitive to disease severity2 and changes in treadmill gradient.3 (Source: Heart and Lung)
Source: Heart and Lung - November 28, 2022 Category: Intensive Care Authors: Craig R. Aitken, Glenn M. Stewart, James R. Walsh, Tanya Palmer, Lewis Adams, Surendran Sabapathy, Norman R. Morris Source Type: research

Existence of “obesity paradox” in cardiogenic shock: More questions than answers
To The Editor, (Source: Heart and Lung)
Source: Heart and Lung - November 28, 2022 Category: Intensive Care Authors: Rohan Magoon, Jes Jose Source Type: research

Survival after multiple episodes of cardiac arrest
Cardiopulmonary resuscitation (CPR) and Advanced Care Life Support (ACLS) are widely used to treat cardiac arrest from a variety of causes. Over 200,000 adult patients undergo in-hospital cardiac arrest in the United States annually.1 As such, considerable efforts have been made over the past couple of decades to improve outcomes of patients undergoing cardiac arrest both outside of and inside the hospital. (Source: Heart and Lung)
Source: Heart and Lung - November 26, 2022 Category: Intensive Care Authors: Bayley A. Jones, Micah A. Thornton, Christopher A. Heid, Kristen L. Burke, Marinda G. Scrushy, Kareem R. Abdelfattah, Steven E. Wolf, Mitri K. Khoury Source Type: research

Nurses ’ knowledge of heart failure assessment and management: A cross-sectional survey
Heart failure (HF) is a chronic condition and a severe public health issue threatening 6500,000 Americans and causing about 300,000 death each year.1,2 HF is also the leading cause of hospital admissions among adults age 65 years or greater, with nearly 1 million annually hospitalized.1 Despite advanced therapy, the death and hospitalization rates remain high in patients with HF, and 67% are readmitted within one year of discharge for exacerbations of HF.3,4 The common cause of preventable readmissions is inadequate knowledge at discharge, inadequate follow-up with nurses or healthcare providers, and nonadherence with the ...
Source: Heart and Lung - November 23, 2022 Category: Intensive Care Authors: Zequan Wang, Stephen Walsh, Christine Tocchi, Yiming Zhang, Deborah Chyun Source Type: research

Respiratory and peripheral muscle strength influence recovery of exercise capacity after severe exacerbation of COPD? An observational prospective cohort study
Acute exacerbation of chronic obstructive pulmonary disease (AECOPD) is characterized as an acute worsening of respiratory symptoms, which is usually triggered by respiratory infections caused by viruses or bacteria.1 Increased airway inflammation, increased mucus production and marked gas trapping are pathophysiological hallmarks of AECOPD that contribute to increased dyspnea and other symptoms such as sputum volume, cough and wheeze.1,2 Consequences of these clinical features lead AECOPD patients to experience a profound negative impact on health status, which often contributes to disease progression and increased rates ...
Source: Heart and Lung - November 23, 2022 Category: Intensive Care Authors: Alessandro D. Heubel, Erika Z. Kabbach, Naiara T. Leonardi, Nathany S. Schafauser, D ébora M.O. Kawakami, Anna Claudia Sentanin, Valéria A. Pires Di Lorenzo, Audrey Borghi Silva, John R. Hurst, Renata G. Mendes Source Type: research

Excess of heart failure-related deaths during the 2020 COVID-19 pandemic in Unites States
Heart failure (HF) represents one of the leading cardiovascular disease and cause of hospitalizations in the US1. HF can be encountered at different stages in the course of COVID-19 disease. However, few investigations have reported epidemiological population-based estimated of HF mortality using contemporary data. To this regard, previous studies have demonstrated that an history of HF confers a higher risk for in-hospital mortality among adults hospitalized with COVID-19, especially in those age more than 65 years and with comorbid conditions2. (Source: Heart and Lung)
Source: Heart and Lung - November 23, 2022 Category: Intensive Care Authors: Marco Zuin, Gianluca FACC RigatelliFSCAI, Claudio Bilato Source Type: research

Developing an explainable machine learning model to predict the mechanical ventilation duration of patients with ARDS in intensive care units
Acute respiratory distress syndrome (ARDS) is a diffuse lung disease caused by inflammatory damage to pulmonary capillary endothelial and alveolar epithelial cells during severe infection, shock, trauma, and burns, which can lead to acute hypoxic respiratory insufficiency or failure.1,2 Globally, 30 –47% of patients in intensive care units (ICUs) are diagnosed with ARDS, and the mortality rate ranges from 35% to 46%.3 In addition to the treatment of primary disease, the primary goal for patients with ARDS is to correct hypoxemia, in which mechanical ventilation (MV) is the most important meth od of respiratory support. (...
Source: Heart and Lung - November 21, 2022 Category: Intensive Care Authors: Zichen Wang, Luming Zhang, Tao Huang, Rui Yang, Hongtao Cheng, Hao Wang, Haiyan Yin, Jun Lyu Source Type: research

Association between inpatient palliative care encounter and 30-day all-cause readmissions after index hospitalization for chronic obstructive pulmonary disease
Chronic Obstructive Pulmonary Disease (COPD) is a prevalent disease and a leading cause of morbidity and mortality.1 –3 COPD has significant economic implications with an estimated $36 billion in total cost attributed to COPD in 2010.4 Hospitalizations account for a major portion of the healthcare-related costs with rehospitalizations alone accounting for over $15 billion annually.5 (Source: Heart and Lung)
Source: Heart and Lung - November 18, 2022 Category: Intensive Care Authors: Ali Yazdanyar, Ashley Vojtek, Sachin Gupta, Aditya Iyer, Alaynna C Kears, Kaitlyn Musco, Shuisen Li, Shadi Jarjous Source Type: research

Factors influencing self-management behavior during the “Blanking Period” in patients with atrial fibrillation: A cross-sectional study based on the information-motivation-behavioral skills model
Atrial fibrillation (AF) is the most prevalent arrhythmia, and its prevalence is rising globally.1 It is strongly linked to heart failure, stroke, and even mortality, which has a negative impact on patients' quality of life and places a significant strain on the worldwide medical system.2,3 Radiofrequency catheter ablation (RFCA), as the first-line treatment for AF around the world, not only can minimize the recurrence and symptoms burden of AF, but also dramatically improve patients' quality of life. (Source: Heart and Lung)
Source: Heart and Lung - November 17, 2022 Category: Intensive Care Authors: Yunmei Ding, Fan Li, Zekai Fan, Jingya Zhang, Jiayun Gu, Xue Li, Lili Wei, Yan Zhang, Hongxuan Xu, Yan Cui Source Type: research