Is prognostic nutritional index a predictive marker for estimating all-cause in-hospital mortality in COVID-19 patients with cardiovascular risk factors?
This study examined the possible association between the prognostic nutritional index (PNI) and in-hospital mortality rates in cases with a high cardiovascular risk burden and hospitalized with the diagnosis of coronavirus disease 2019 (COVID-19). (Source: Heart and Lung)
Source: Heart and Lung - January 13, 2021 Category: Intensive Care Authors: Tufan Çınar, Mert İlker Hayıroğlu, Vedat Çiçek, Şahhan Kılıç, Süha Asal, Samet Yavuz, Murat Selçuk, Emre Yalçınkaya, Nurgül Keser, Ahmet Lütfullah Orhan Source Type: research

Why is early mobility immobilized?
Critical care research and evidence-based practice guidelines support implementation of the ABCDEF bundle regimen to improve liberation from mechanical ventilation and patient neurocognitive and physical functional outcomes. However, consistent daily adherence to the bundle protocol with all eligible intensive care unit (ICU) patients has been difficult and suboptimal.1 Boehm and colleagues address early mobility (E), the bundle component with poorest implementation rates, from the perspective of the interprofessional team members responsible for planning and executing this intervention. (Source: Heart and Lung)
Source: Heart and Lung - January 12, 2021 Category: Intensive Care Authors: Mary Beth Happ, Audrey S. Brockman, Cynthia Moore Source Type: research

D-dimer and Poor Clinical Outcome in Patients with COVID-19: Lessons from Meta-analysis of Case-Control Studies
Over a year has passed since the coronavirus diseases 19 (COVID-19) has been with us . During this time, an exponentially increasing number of papers describing risk scores, outcome assessment questionnaires, and mortality predictors have been published with heterogeneous validity and uncertain clinical utility. Nevertheless, systematic reviews and meta-analysis are always an important tool in highlighting high-quality clinical studies and determining our current place in the extensively broad literature. (Source: Heart and Lung)
Source: Heart and Lung - January 12, 2021 Category: Intensive Care Authors: Saeed Shoar Source Type: research

Alternative Cardiac Intensive Care Unit Locations during the COVID-19 pandemic at an Academic Medical Center
Due to the COVID-19 pandemic, hospitals around the globe have been inundated with critically-ill patients, which necessitate airborne isolation precautions and alterations in Intensive Care Unit (ICU) nursing and provider practices.1 In addition, the sheer number of patients have overwhelmed ICU bed capacity in some locations, with several reports of hospitals who were forced to make difficult triage decisions limiting care for critically-ill patients with and without COVID-19.2,3 Several descriptions of expanding medical ICU bed capacity to accommodate COVID patients have been described. (Source: Heart and Lung)
Source: Heart and Lung - January 9, 2021 Category: Intensive Care Authors: Marlene S. Williams, Sammy Zakaria, Michelle D'Alessandro, Susan Kraeuter, Heather Hicks Source Type: research

Ventricular Septal Rupture and Cardiogenic Shock Complicating STEMI during COVID-19 Pandemic: An Old Foe Re-Emerges
The incidence of mechanical complications secondary to acute myocardial infarction (AMI) has declined significantly in the past few decades due to advances in early reperfusion with primary percutaneous intervention (PCI) strategy.1 Despite a decline in the number of hospitalizations for acute coronary syndromes in the early months of the COVID-19 pandemic 2, the incidence of mechanical complications has risen.3 This is most likely due to delay in revascularization, which is an established risk factor for development of mechanical complications following AMI. (Source: Heart and Lung)
Source: Heart and Lung - December 22, 2020 Category: Intensive Care Authors: Hooman Bakhshi, Raghav Gattani, Emmanuel Ekanem, Ramesh Singh, Mehul Desai, Alan M. Speir, Shashank S. Sinha, Matthew W. Sherwood, Behnam Tehrani, Wayne Batchelor Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - December 12, 2020 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - December 12, 2020 Category: Intensive Care Source Type: research

Leadership Message
(Source: Heart and Lung)
Source: Heart and Lung - December 12, 2020 Category: Intensive Care Source Type: research

Heparan Sulfate Consumption as a Potential Mechanism of Intra-cardiac Thrombosis in SARS-CoV-2 Infection
Cardiac injury occurs in up to 36% of hospitalized patients with COVID-19.1 Exact mechanism of cardiac injury in COVID-19 is not well understood, but may relate to direct cardiomyocyte damage, coronary plaque destabilization, cytokine inflammatory response, and intracoronary microthrombi formation. Lindner et al 2 in an autopsy study identified SARS-CoV-2 RNA in the myocardium in 24 of 39 autopsy cases. However, none of the 39 patients had myocarditis. Plasma pro-inflammatory cytokine levels were increased in 16 patients, suggesting cytokine response as a plausible cause of cardiac injury in COVID-19. (Source: Heart and Lung)
Source: Heart and Lung - December 9, 2020 Category: Intensive Care Authors: Husam M. Salah, Jawahar L. Mehta Source Type: research

Clinical outcomes of pleural drainage on pneumothorax and hydrothorax in critically ill patients with COVID-19: A case series with literature review
On March 19, 2020, the WHO characterized coronavirus disease 2019 (COVID-19) as a global pandemic. As of Oct 25, 2020, the widespread human-to-human transmission of SARS-CoV-2 has resulted in> 4,2830,000 cases, with> 1,150,000 deaths. The clinical severity of COVID-19 varies greatly, from asymptomatic to death. Pneumothorax and hydrothorax have been reported in patients with COVID-19, especially in critically ill patients. Although it has been suggested that pneumothorax can cause death1 and hydrothorax is a negative prognostic indicator,2 the management of these two conditions is rarely discussed. (Source: Heart and Lung)
Source: Heart and Lung - December 9, 2020 Category: Intensive Care Authors: Yuan Xu, Shanqing Li, Hongsheng Liu Source Type: research

COVID-19 and Spontaneous Pneumomediastinum: A Case Series
COVID-19 is an ever-evolving disease that the medical community continues to learn more about daily. It is important to highlight important clinical courses that are not common so that adverse events can be better predicted and treated appropriately. In a retrospective study done in a hospital out of Wuhan, China in February 2020 showed that out of its 99 patients, only one patient had pneumothorax.1 Later, in March 2020, a literature review published in the American Journal of Roentgenology of more than 900 patients described the incidence of pneumothorax as uncommon or rare. (Source: Heart and Lung)
Source: Heart and Lung - December 4, 2020 Category: Intensive Care Authors: Alex Diaz, Dolly Patel, Najia Sayedy, Fatima Anjum Source Type: research

Management of cardiogenic shock by circulatory support during reverse Tako-Tsubo following amphetamine exposure: A report of two cases
Stress-induced cardiomyopathy was first described in Japanese patients as Tako-Tsubo cardiomyopathy (TTC).1 This syndrome mimicking acute myocardial infarction with normal coronary arteries is predominantly preceded by emotional and/or physical triggers and is characterized by transient left ventricular apical ballooning. Many variations of this syndrome have been recently described in the literature.2 One of the rarest is reverse or inverted type of this syndrome with hyperdynamic apex and complete akinesia of the base. (Source: Heart and Lung)
Source: Heart and Lung - November 24, 2020 Category: Intensive Care Authors: Pierre-Antoine Cotinet, Philippe Bizouarn, Fran çois Roux, Bertrand Rozec Source Type: research

Initial CT scan and its relationship with Covid-19
This study has shown that CT findings may be related to admission to intensive care unit (ICU), intubation and mortality. As is known, COVID-19 patients with hypertension, card io-cerebrovascular diseases and diabetes are more frequently admitted to ICU.2 Patients with heart and renal insufficiencies show more ground glass opacities (GGO) on CT scan. (Source: Heart and Lung)
Source: Heart and Lung - November 18, 2020 Category: Intensive Care Authors: Serdar Kalemci, Ayd ın Sarıhan, Arife Zeybek Source Type: research

Congestion and nutrition as determinants of bioelectrical phase angle in heart failure
The whole-body bioelectrical phase-angle (PhA) is emerging as a new tool in stratifying prognosis in patients with both acute (AHF) and chronic heart failure (CHF). (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Pietro Scicchitano, Marco Matteo Ciccone, Andrea Passantino, Roberto Valle, Micaela De Palo, Paolo Sasanelli, Mariella Sanasi, Assunta Piscopo, Piero Guida, Pasquale Caldarola, Francesco Massari Source Type: research

Early extubation in current valve surgery requiring long cardiopulmonary bypass: Benefits and predictive value of preoperative spirometry
At present, fast-track cardiac anesthesia is widely used, and successful early extubation of the trachea (EEx) is a goal in improving post-operative management after cardiac surgery with cardiopulmonary bypass (CPB).1 EEx is usually defined as removal of the endotracheal tube within 8  h in the intensive care unit (ICU) of completion of surgery.2 The success rate of EEx is affected by several peri‑operative factors,3 and CPB time is known to be a strong predictor of successful EEx.4,5 In previous studies, the success rates of EEx rates were usually recorded after coronary arte ry bypass grafting (CABG), with a relat...
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Atsushi Hiromoto, Motohiro Maeda, Tomohiro Murata, Makoto Shirakawa, Junichi Okamoto, Yuji Maruyama, Hajime Imura Source Type: research

The role of health literacy, depression, disease knowledge, and self-efficacy in self-care among adults with heart failure: An updated model
Affecting over 6.2 million Americans ages 20 and older1 with worldwide estimates over 26 million, the prevalence of heart failure ranges from 1.3% of the population of some countries to as high as 6.7% in others.2 Although survival continues to improve, costs to treat heart failure in the United States may be as high as $60.2 billion with $10.6 billion in indirect costs.3 This is particularly concerning as the incidence of heart failure is projected to continue to increase in the next decade and a half, resulting in over 8 million diagnosed by 2030. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Aleda M.H. Chen, Karen S. Yehle, Kimberly S. Plake, Lisa D. Rathman, J.Wes Heinle, Robert T. Frase, James G. Anderson, John Bentley Source Type: research

The Mediator Effects of Depressive Symptoms on the Relationship between Family Functioning and Quality of Life in Caregivers of Patients with Heart Failure
There are approximately 6.5 million patients in the United States currently diagnosed with HF. In order to improve outcomes, HF patients must perform effective HF self-care.1 As most patients with HF are elderly and impaired, HF self-care usually requires assistance from caregivers.2 Caregiving can be rewarding to some caregivers; however, many caregivers suffer from depressive symptoms and poor quality of life (QOL) as a consequence of caregiving.3 Caregivers often neglect their self-care and social relationships in order to perform HF caregiving. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Linda Clements, Susan K. Frazier, Debra K. Moser, Terry A. Lennie, Misook L. Chung Source Type: research

Incidence and clinical outcomes of nosocomial infections in patients presenting with STEMI complicated by cardiogenic shock in the United States
Nosocomial infections (NI) complicating hospitalizations for cardiovascular diseases are associated with increased healthcare costs, length of stay and in-hospital mortality.1,2 Cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI-CS) is frequently accompanied by a noninfectious systemic inflammatory response.1,3 The degree of overlap of this response with an early infectious complication is unclear, thus making the detection of a coexisting infection difficult.1 Rates of infections in non-CS patients with STEMI following cardiac interventions such as cardiac catheterization and percutaneous coronary ...
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Omar Chehab, Rami Z. Morsi, Amjad Kanj, Rayan Jo Rachwan, Mohit Pahuja, Shareef Mansour, Hussam Tabaja, Usman Ahmad, Said El Zein, Mohammad Raad, Ali Saker, Paulino Alvarez, Alexandros Briasoulis Source Type: research

Direct postoperative protein S100B and NIRS monitoring in infants after pediatric cardiac surgery enrich early mortality assessment at the PICU
Cerebral injury resulting from cardiac surgery depicts a devastating complication that can have severe effects on the neurological outcome.1 While this can be attributed to the inherent nature of cardiac disease, with possible hypoxemia and cyanosis, the surgical procedure itself poses its own risk, owing in particular to the use of cardiopulmonary bypass (CPB); potentially leading to compromised circulation, hypoxia and systemic inflammation, as reported after adult cardiac surgery.2,3 The use of plasmatic cerebral biomarkers for detecting cerebral damage, such as neuromonitoring, has been well-established since the 1990s...
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Stefan Irschik, Sabrina Stelzl, Johann Golej, Gerald Schlager, Daniel Zimpfer, Claudia Herbst, Ina Michel-Behnke, Erwin Kitzm üller, Eva Base, Michael Hermon Source Type: research

Long-term exercise adherence in patients with heart failure: A qualitative study
Participation in regular exercise for healthy adults is associated with several positive outcomes, such as reduced risk of mortality, decreased risk of depression, and reductions in health care spending.1 Yet, approximately half of American adults do not meet the recommended amount of weekly exercise.1 This issue is amplified for patients with heart failure (HF). The Heart Failure Society of America recommends patients with HF participate in 30 min of moderate intensity exercise in a supervised setting five-days per week. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Shane Warehime, Danae Dinkel, Windy Alonso, Bunny Pozehl Source Type: research

Obesity across the lifespan in congenital heart disease survivors: Prevalence and correlates
In 2010, an estimated 2 million individuals with congenital heart disease (CHD) were living in the U.S.1 CHD survivors are at greater risk for numerous cardiovascular comorbidities as they age, including atherosclerosis,2 hypertension, and heart failure.3 Due to improved survival, the population of adult CHD survivors has increased by more than 60% over recent years,4 highlighting the need for cardiovascular risk reduction across the lifespan. Furthermore, hospital admissions for coronary disease and heart failure have increased among adults with CHD, by 119% and 83%, respectively, between 1998 and 2010,5 resulting in more...
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Jamie L. Jackson, Kristen R. Fox, Jennifer Cotto, Tondi M. Harrison, Andrew H. Tran, Sarah A. Keim Source Type: research

Effect of exercise capacity on perception of dyspnea, psychological symptoms and quality of life in patients with chronic obstructive pulmonary disease
Currently, in addition to their high prevalence, morbidity and mortality rates, chronic lung diseases pose a worldwide major health problem affecting the quality of life of patients in a negative way.1 Chronic obstructive pulmonary disease (COPD), leads to physical, psychological and social problems in addition to being associated with a poor quality of life.2 Dyspnea which is a major symptom in COPD patients is the most important factor that impairs quality of life.3 Activities of daily living of COPD patients are considerably diminished because of dyspnea and physical deconditioning and exercise intolerance is developed....
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Sahin Hulya, Naz Ilknur, Polat Gulru Tags: Original article Source Type: research

Cardiac sarcoidosis as an incidental finding: A case report
This case illustrates the evaluation of a healthy young male with ECG anomalies in a perioperative electrocardiogram (ECG) that ended up with the diagnosis of a severe systemic disease. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Ana Gabaldon-Perez, Sergio Garcia-Blas, Maria J. Forner, Maria Pilar L ópez-Lereu, Clara Bonanad Source Type: research

New-onset arrhythmia associated with patients hospitalized for thyroid dysfunction
Thyroid dysfunction is a well-established risk factor for clinically significant cardiovascular-related adverse outcomes.1,2 Both lack of thyroxine (T4), as in hypothyroidism, and an excess of triiodothyronine (T3), as in hyperthyroidism, have been shown to result in changes of cardiac contractility and vascular resistance, as well as increased adrenergic effects and chronotropic/inotropic stimulation, respectively.3,4 Regarding rhythm-based disturbances, a lack of T4 has been linked to bradyarrhythmia as well as ventricular tachycardia and acquired long-QT syndrome - which increases the risk of torsade de pointes. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Rajkumar Doshi, Tania Dhawan, Casey Rendon, Marines Acevedo Rodriguez, Kavitha Nutakki, Jennifer Gianopulos, Rupak Desai, Saraschandra Vallabhajosyula, Devina Adalja, Palakkumar Patel, Nageshwara Gullapalli Source Type: research

Incidence of immediate postextubation complications in critically Ill adult patients
Endotracheal extubation is a procedure commonly performed in intensive care units, which consists in the removal of an endotracheal tube from the trachea.1 This procedure may result in several complications, either in the short or long term; thus, patients should be closely monitored after extubation. Complications include impaired gas exchange, bronchospasm, severe cough, upper airway (UA) obstruction from laryngospasm, laryngeal edema or cord impairment, atelectasis, aspiration, pulmonary edema, apnea and hemodynamic instability. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Mauro Federico Andreu, Marco Guillermo Bezzi, Mar ía Eugenia Dotta Source Type: research

Prognostic value of microalbuminuria on admission in patients with acute pulmonary embolism
Acute pulmonary embolism (APE) is not only associated with a high rate of morbidity and mortalitya but also associated with increased costs worldwide.1 Thus, early prediction of adverse events have been increasingly important to guide the management of patients with APE.2,3 Previous studies have reported that older age,  hemodynamic instability, high levels of natriuretic peptides and troponins, and higher burden of comorbidities are associated with a poor prognosis in APE.4–6 Several tools such as pulmonary embolism severity index (PESI) have also been developed for assessing the severity of the disease. (...
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Ömer Doğan Alataş, Murat Biteker Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Source Type: research

Telemedicine in Heart Failure during COVID-19: Like it, Love It or Lose It?
The onset of Coronavirus disease 2019 (COVID-19) led to social distancing and stay-at-home recommendations to slow a surge in cases. Many hospitals and ambulatory medical services abruptly halted usual care services to participate in social distancing and prepare for intensive care admissions. Slowing of office services meant that providers of patients with chronic heart failure (HF) needed to find new ways to communicate with and manage patients since up to 90% of patients have symptoms, and at any time, over 30% have New York Heart Association functional class III or IV symptoms. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Nancy M. Albert, Marilyn A. Prasun Source Type: research

Factors influencing physical activity after cardiac surgery: An integrative review
Heart disease has been the number one cause of death worldwide over the last 15 years.1 In the United States, more than 610,000 people die annually from heart disease, accounting for one-fourth of all deaths.2 Approximately 30.3 million people were known to have heart disease in the United States in 2018,2 and cardiac surgery is routinely performed to ameliorate these issues. Types of cardiac surgery include coronary artery bypass grafting (CABG), heart valve repair or replacement, heart transplant, and placement of ventricular assist devices or artificial hearts. (Source: Heart and Lung)
Source: Heart and Lung - November 1, 2020 Category: Intensive Care Authors: Sueyeon Lee, Eileen G. Collins Source Type: research

Concurring hypertrophic cardiomyopathy and takotsubo cardiomyopathy: Assessment and management
Hypertrophic obstructive cardiomyopathy (HOCM) and takotsubo cardiomyopathy (TCM) are two distinct myocardial disease entities that rarely coexist.1 HOCM is the most common genetic cardiomyopathy and the most common cause of sudden cardiac death, yet there is an overwhelming lack of high-level evidence regarding the approach to its work-up and management.2 Takotsubo cardiomyopathy is a newer entity however, first described in the late 20th century in Japan,3 where its name was derived from the Japanese word for “octopus trap” which it resembles in appearance in its most classical form. (Source: Heart and Lung)
Source: Heart and Lung - October 31, 2020 Category: Intensive Care Authors: Mohammed Abozenah, Anis John Kadado, Ahmad Aljamal, Khalid Sawalha, Colby Salerno, Ayman Battisha, Jaime Hernandez-Montfort, Amir Lotfi Source Type: research

Manual bag valve mask ventilation performance among respiratory therapists
The bag valve mask (BVM) serves as an important tool for ventilating patients in an acute care setting. Also known as a manual resuscitator, the BVM is frequently used by respiratory therapists (RTs) during cardiopulmonary resuscitation (CPR), patient transport, rapid response scenarios, and other emergencies. Proper ventilation techniques with the BVM should consider safe ventilation parameters for each individual patient and their conditions. Excessive volume, pressure or flow may result in morbidity from lung damage, stomach insufflation, or hemodynamic and pulmonary compromise. (Source: Heart and Lung)
Source: Heart and Lung - October 31, 2020 Category: Intensive Care Authors: Rachel E. Culbreth, Douglas S. Gardenhire Source Type: research

Arterial oxygen pressure targets in critically ill patients: Analysis of a large ICU database
Oxygen administration is now one of the most routine therapies in critically ill patients and frequently represents a lifesaving strategy. In the intensive care unit (ICU), oxygen therapy and oxygenation status play an important role in the clinical course of patients. Monitoring and maintaining an optimal titration of oxygen therapy is a crucial component of treating critical diseases. Blood oxygen levels are commonly measured continuously using pulse oximetry or intermittently using arterial oxygen pressure (PaO2). (Source: Heart and Lung)
Source: Heart and Lung - October 31, 2020 Category: Intensive Care Authors: Chang Xu, Dan-wei Jiang, Wei-yong Qiu, Yan-xue Zhou, Long-wang Chen, Guang-liang Hong, Guang-ju Zhao, Zhong-qiu Lu Source Type: research

Pericardial effusion after pediatric cardiac surgery: A single-center study
Postoperative pericardial effusion (pPE) still remains a frequent complication after congenital heart surgery and it usually leads to an increased morbidity and re-hospitalization rate.1 Congenital heart diseases (CHD) usually require two or more operations over time as the child grows. For this reason, post-surgical adherences are very frequent, and they increase a lot the risk of pPEs. These can affect up to 20% of surgically treated patients, most of which usually occur during the first month after the operation. (Source: Heart and Lung)
Source: Heart and Lung - October 22, 2020 Category: Intensive Care Authors: Raffaele Giordano, Giuseppe Comentale, Luigi Di Tommaso, Ettorino Di Tommaso, Vito Antonio Mannacio, Emanuele Pilato, Gabriele Iannelli, Gaetano Palma, Massimiliano Cantinotti Source Type: research

Outcomes of patients with COVID-19 in the Intensive Care Unit in Mexico: A multicenter observational study
As of June 15, 2020, a cumulative total of 7,823,289 confirmed cases of coronavirus disease 2019 (COVID-19) have been reported across 216 countries and territories worldwide1. A total of 150,262 confirmed cases of COVID-19 and 17,580 deaths have been reported in Mexico2. Approximately 3% (4,555/150,262) of these patients presented rapidly progressive respiratory failure and required endotracheal intubation and invasive mechanical ventilation2. The COVID-19 pandemic continues to pose a major public health threat to Latin American countries, including Mexico. (Source: Heart and Lung)
Source: Heart and Lung - October 21, 2020 Category: Intensive Care Authors: Silvio A. Ñamendys-Silva, Pedro E. Alvarado-Ávila, Guillermo Dominguez-Cherit, Eduardo Rivero-Sigarroa, Luis Sánchez-Hurtado, Alan Gutiérrez-Villaseñor, Juan P. Romero-González, Heber Rodríguez-Bautista, Alondra García-Briones, César E. Garnica-C Source Type: research

Left ventricular thrombi in malignancy: A therapeutic dilemma
Warfarin is the current standard of care for left ventricular thrombi (LVT).1,2 However, in the setting of malignancy, warfarin is of notoriously low efficacy. We highlight clinically useful data for maneuvering this catch-22 of LVT in malignancy, and expose the need for conclusive prospective studies. (Source: Heart and Lung)
Source: Heart and Lung - October 20, 2020 Category: Intensive Care Authors: Michael Brandon Omar, Satish Maharaj Source Type: research

A cross-sectional analysis of binge drinking levels in US myocardial infarction survivors
An estimated 805,000 myocardial infarctions (MIs) occur annually in the US with 605,000 of these being new MIs and recurrent MIs making up the remaining 200,000.1,2 After a first MI, the risk of hospitalization for a recurrent MI within the following five years is around 20%.2,3 Individuals who suffer a recurrent MI are also, respectively, 1.5 and 3 times more likely to die from any cause compared to similarly aged individuals who have only had one MI and those who have not had a MI.4 Due to the higher mortality associated with recurrent MIs, the American Heart Association recommends that MI survivors control their weight ...
Source: Heart and Lung - October 20, 2020 Category: Intensive Care Authors: Phoebe Tran, Lam Tran, Liem Tran Source Type: research

Pattern of anticoagulation prescription for patients with Covid-19 Acute Respiratory Distress Syndrome admitted to ICU. Does it impact outcome?
Covid-19 also called novel coronavirus, has affected 16Millions people with 644K death as of July 26th, 2020, worldwide1. Covid-19 (SARS CoV-2) spread rapidly via person to person contact and attacks predominantly respiratory system2. Covid-19 infection is associated with inflammation and microvascular thrombosis3-4, as reflected by elevated markers of inflammation (ferritin, CRP) and D-Dimers5, respectively. It may cause pulmonary micro-thrombosis6, leading to a ventilation-perfusion (VQ) mismatch. (Source: Heart and Lung)
Source: Heart and Lung - October 20, 2020 Category: Intensive Care Authors: Rashid Nadeem, Stelvie John Thomas, Zoubia Fathima, Anju Subin Palathinkal, Yazan Emad Alkilani, Efaf Ahmad Dejan, Ismail mohammad ismail Darwish, Aisha Ali Alsubousi, Alaa Marouf Backour, Hussein Kandeel, Mohamad Omar, Hesham Fawzy Yehia Taha Kewan, Mahm Source Type: research

Myocarditis, paraparesia and ARDS associated to COVID-19 infection
An 18 year-old female patient with no medical history, no recent travel or exposure to animals, presented with fever and dyspnea to the Emergency Department on April 1st, 2020. She had been exposed to COVID-19 as her grandmother had tested positive two weeks earlier. As the symptoms were perfectly tolerated and there was no risk factor of severe infection, she was discharged without any laboratory testing. (Source: Heart and Lung)
Source: Heart and Lung - October 19, 2020 Category: Intensive Care Authors: Lina Jeantin, Claire Pichereau, Marc Pineton de Chambrun, Omar Ben Hadj Salem, Jan Hayon, Yann Loubi ères, Valentin Landon, Mikael Alves, Christophe Barbier, Siu Ming Au, Lionel Lima da Silva, Alain Combes, Hervé Outin, Matthieu Jamme Source Type: research

Clinical Course of COVID-19 Patients Treated with ECMO: a Multicenter Study in Daegu, South Korea
The novel corona viral disease 2019 (COVID-19) has now infected over 6 million people worldwide. In Korea, over 10,000 people have been diagnosed with COVID-19 infection, and Daegu was the first epicenter of the outbreak. The spectrum of the clinical manifestations of COVID-19 is broad, ranging from mild disease to critical disease. In the largest case series reported by the Chinese Centers for Disease Control, 5% of patients were critical, presenting with respiratory failure, septic shock, and/or multiple organ dysfunction or failure. (Source: Heart and Lung)
Source: Heart and Lung - October 19, 2020 Category: Intensive Care Authors: Woo Sung Jang, JaeBum Kim, Jonghyun Baek, Hanna Jung, Jae Seok Jang, Jae Seok Park, Tak-Hyuk Oh, Se Yong Jang, Yun Seok Kim, Yong Shik Kwon Source Type: research

Leadership Message
(Source: Heart and Lung)
Source: Heart and Lung - October 16, 2020 Category: Intensive Care Source Type: research

A bridge to transplantation: The life experiences of patients with a left ventricular assist device
Heart failure (HF) has affected at least 26 million people all over the world and is becoming more common day by day.1 In USA, 870,000 new cases per year have been recorded on top of the existing 5.7 million cases.2 Although Turkey has a young population, HF prevalence is significantly high as around 2.5 million adults have experienced HF.3,4 (Source: Heart and Lung)
Source: Heart and Lung - October 15, 2020 Category: Intensive Care Authors: Fatma Cebeci, Bilgen Arikan, Emine Catal, Omer Bayezid Source Type: research

Prevalence and manifestations of diagnosed fibromuscular dysplasia by sex and race: Analysis of > 4500 FMD cases in the United States
Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory disease of small and medium sized arteries associated with abnormal development of vessel media or intima, and is predominantly seen in young females1. It can potentially involve any vascular bed with renal arteries being the most commonly affected (65 –70%) followed by cervicocranial arteries (25–30%)1. The location of involved segment determines symptoms, which commonly include headache, hypertension and pulsatile tinnitus2; however, most patients are asymptomatic. (Source: Heart and Lung)
Source: Heart and Lung - October 15, 2020 Category: Intensive Care Authors: Mariam Nadeem Rana, Sadeer G. Al-Kindi Source Type: research

A crossroads at the understanding of pulmonary hypertension in end stage renal disease
In 2015, almost 700,000 people in the United State were undergoing treatment for End Stage Renal Disease (ESRD), a number that is projected to increase to between 971,000 and 1259,000 by 2030.1 ESRD is known to portend significant morbidity and mortality, most commonly caused by cardiovascular disease. Pulmonary Hypertension (PH) is defined as the mean pulmonary artery pressure (mPAP) ≥20 mmHg, as measured by right heart catheterization and affects a significant proportion of the ESRD population. (Source: Heart and Lung)
Source: Heart and Lung - October 14, 2020 Category: Intensive Care Authors: Alexander J. Gazda, Maria M.Patarroyo Aponte, Aleksandra De Golovine, Angelina Edwards, Akshta Pai, Bindu H. Akkanti Tags: Letter to Editor Source Type: research

Different value of HDL-C in predicting outcome of ARDS secondary to bacterial and viral pneumonia: A retrospective observational study
Acute respiratory distress syndrome (ARDS) is characterized by an excessive pulmonary inflammatory response, with 10% of prevalence in intensive care unit patients and a high mortality (30 –40%).1 To date, there is no single biomarker effective enough to predict clinical outcome of ARDS, owing to its clinical and biological heterogeneity.2 The incidence of ARDS is associated with the setting of pneumonia, nonpulmonary sepsis, aspiration of gastric contents, severe trauma and acute p ancreatitis, among which pneumonia (bacterial and viral, fungal is less common) is being a common risk factor as 59.4% of pneumonia pati...
Source: Heart and Lung - October 14, 2020 Category: Intensive Care Authors: Liu Yang, Zujin Luo, Xiaoqian Shi, Baosen Pang, Yingmin Ma, Jiawei Jin Source Type: research

A multisite study of multidisciplinary ICU team member beliefs toward early mobility
Early mobility is underutilized in critical care. (Source: Heart and Lung)
Source: Heart and Lung - October 14, 2020 Category: Intensive Care Authors: Leanne M. Boehm, Jana Lauderdale, Amy N. Garrett, Susan E. Piras Source Type: research

High Incidence and Mortality of Pneumothorax in Critically Ill Patients with COVID-19
From the outbreak of 2019 novel coronavirus disease (COVID-19) in December 2019 to Mar 27, 2020, and the number of confirmed patients and deaths outside of China is increasing rapidly all around the world.1 The autopsy of a patient who died from severe infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) showed evident desquamation of pneumocytes, hyaline membrane formation and pulmonary edema, suggesting acute respiratory distress syndrome (ARDS).2 Xun et al. reported that all of 25 patients with COVID-19 died of SARS-CoV-2 infection complicated by respiratory failure, suggesting that lung is the ma...
Source: Heart and Lung - October 14, 2020 Category: Intensive Care Authors: Xiao-hui Wang, Jun Duan, Xiaoli Han, Xinzhu Liu, Junhao Zhou, Xue Wang, Linxiao Zhu, Huaming Mou, Shuliang Guo Source Type: research

Predictive Value of Initial CT scan for Various Adverse Outcomes in Patients with COVID-19 Pneumonia
In late 2019, clustered pneumonia cases were reported from the city of Wuhan in the Hubei province of China. Later in January 2020, WHO declared this issue as a public health emergency of international concern (PHEIC),1 and the disease itself was named COVID-19. Later the virus was designated as SARS-CoV-2 relating to its predecessor SARS-CoV, responsible for the SARS epidemic in 2003. On February 18, 2020, Iran's first case of COVID-19 was reported from Qom city. Later, in March 2020, WHO declared COVID-19 a pandemic. (Source: Heart and Lung)
Source: Heart and Lung - October 14, 2020 Category: Intensive Care Authors: Bardia Khosravi, Leila Aghaghazvini, Majid Sorouri, Sara Naybandi Atashi, Mohammad Abdollahi, Helia Mojtabavi, Marjan Khodabakhshi, Fatemeh Motamedi, Fatemeh Azizi, Zeynab Rajabi, Amir Kasaeian, Ali Reza Sima, Amir H. Davarpanah, Amir Reza Radmard Source Type: research

The impact of an advance care planning intervention for patients hospitalized with acute decompensated heart failure
Many patients with heart failure (HF) have not addressed end-of-life planning. (Source: Heart and Lung)
Source: Heart and Lung - October 8, 2020 Category: Intensive Care Authors: Therese Crowley Prentice, Robin Lawson Source Type: research

Case report: Nutrition therapy and side-effects monitoring in critically ill coronavirus disease 2019 patients
In December 2019, a cluster of cases of pneumonia of unknown pathogen was identified in Wuhan, Hubei, China1. The pathogen was quickly revealed as a novel betacoronavirus named as severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2), and the pneumonia was named as coronavirus disease 2019 (COVID-19) by World Health Organization (WHO)2. WHO declared the outbreak of the disease as a public health emergency of international concern (PHEIC) on 30 January 20202. COVID-19 is highly contagious and has rapidly spread to the world, affecting more than 180 countries and over 15,000,000 people3. (Source: Heart and Lung)
Source: Heart and Lung - October 1, 2020 Category: Intensive Care Authors: Hanxiao Chen, Yu Xue, He Yu, Hong Chen, Yang Li, Yi Chen, Yuwei Zhang Source Type: research