Newer oral antivirals for COVID-19: are they the real game changer?
The unprecedented increase in COVID-19 cases globally following the emergence of novel variants such as Delta and Omicron has led to a focus on the concept of “Hit early, Hit hard” to prevent the progression of mild/moderate illness by accelerating viral clearance into a more severe one. Remdesivir, the only FDA approved antiviral against COVID-19, has its own limitations necessitating hospital visit. Similarly, monoclonal antibodies are plagued by it s high cost, limited availability and need for a hospital-based administration. (Source: Heart and Lung)
Source: Heart and Lung - January 18, 2022 Category: Intensive Care Authors: Shekhar Kunal, Pirabu Sakthivel, Nipun Malhotra, Pranav Ish Source Type: research

Perceptions of Changes in Practice Patterns and Patient Care among Heart Failure Nurses During the COVID-19 Pandemic
The Coronavirus (COVID-19) had a profound impact on the delivery of care in both hospital and outpatient settings across the United States. Patients with heart failure (HF) and healthcare providers had to abruptly adapt. (Source: Heart and Lung)
Source: Heart and Lung - January 13, 2022 Category: Intensive Care Authors: Marilyn A. Prasun, John R. Blakeman, Karen Vuckovic, MyoungJin Kim, Nancy Albert, Kelly D. Stamp, Tiny Jaarsma, Barbara Riegel Source Type: research

Respiratory Rehabilitation in Patients Recovering from Severe Acute Respiratory Syndrome: A Systematic Review and Meta-analysis
Severe acute respiratory syndrome (SARS) is a serious health concern, a rapidly progressive respiratory syndrome, which is caused by severe acute respiratory syndrome coronavirus-1 (SARS-CoV-1) and coronavirus-2 (SARS-CoV-2). SARS-CoV was identified as a global threat in 2003 (SARS-CoV-1) and 2019 (SARS-CoV-2).1, 2 (Source: Heart and Lung)
Source: Heart and Lung - January 13, 2022 Category: Intensive Care Authors: Apurba Barman, Mithilesh K Sinha, Jagannatha Sahoo, Debasish Jena, Vikas Patel Source Type: research

Negative pressure therapy as a safe alternative in the treatment of massive subcutaneous emphysema in critically ill patients COVID-19
Many surgical treatments have been described for massive subcutaneous emphysema (MSE) over the recent years. However, there is no consensus on which is the most recommended and there is great diversity in treatment. With new advances in minimally invasive therapy performed at the bedside, especially in intensive care units, it has been possible to increase therapeutic efficacy. During the COVID-19 pandemic, some therapeutic techniques have been discussed in critically ill patients with SARS-COV-2 respiratory infections, because of the potential overexposure of healthcare personnel to an increased risk of contagion after di...
Source: Heart and Lung - January 12, 2022 Category: Intensive Care Authors: Álvaro Soler-Silva, Luis Sánchez-Guillén, Francisco López Rodriguez-Arias, Antonio Arroyo Source Type: research

Incidence of cardiac complications following COVID-19 infection: An umbrella meta-analysis study
COVID-19 usually presents with symptoms of a respiratory infection, but extra-pulmonary symptoms, including neurological, respiratory, renal, and cardiac complications, are also common1. Cardiac diseases are more prevalent in hospitalized patients with COVID-19 2. Studies have reported different incidence rates of cardiac injuries from 4.2 to 25 3 –7. The incidence is higher in COVID-19 patients with severe disease 7. (Source: Heart and Lung)
Source: Heart and Lung - January 9, 2022 Category: Intensive Care Authors: Mehdi Jafari-Oori, Manijeh Dehi, Abbas Ebadi, Seyyed Tayeb Moradian, Mojtaba jafari Source Type: research

Echocardiographic 60-day mortality markers in patients hospitalized in intensive care for covid-19
The virus of the Severe Acute Respiratory Syndrome – Coronavirus 2 (SARS-CoV-2) is the cause of a fast propagation disease denominated COVID-19. Its epidemiological behavior is characterized by the appearance of recurrent outbreaks exhibiting a large number of patients that develop multiorgan dysfunction that quickly overwhelms the capacity of hea lth services due to the excessive requirement for hospitalizations in intensive care [1]. An important component in this dysfunction is the cardiac involvement that has been attributed to multiple pathophysiological mechanisms among which is the viral direct injury, hypoxem...
Source: Heart and Lung - January 2, 2022 Category: Intensive Care Authors: John Jaime Sprockel D íaz, Juan Manuel Rincon, Manuela Alejandra Rondón López, Marisol Bejarano Zuleta, Nathaly Castellanos, Zulima Santofimio Saavedra, Hellen Cárdenas Rodríguez, Diego Felipe Hernandez Barrera, Jhon Edison Parra, Juan José Diaztagl Source Type: research

Reconsideration of the ECG in pericarditis; have we been led astray all these years?
An 18y old male with no significant past medical history presented with complaints of chest pain typical for pericarditis. He was found to have diffuse ST-segment elevations, elevation of plasma C-reactive protein (CRP) slight elevation of plasma cardiac troponin. The evolution of ECG changes (Fig.  1, a and b) was not typical of ischemic disease. (Source: Heart and Lung)
Source: Heart and Lung - December 29, 2021 Category: Intensive Care Authors: Francesco Mangini, Robert W. Biederman Source Type: research

March/April - Leadership message
The American Association of Heart Failure Nurses (AAHFN) promoted another successful Heart Failure Awareness week in February 2022. AAHFN celebrates Heart Failure Awareness week each year with a theme directed towards heart failure patients and/or caregivers. This year's theme was Transitions of Care. I hope you found the resources helpful and shared them with your colleagues, patients and their caregivers. Hand-off communication between nurses and facilities is one of the most important activities to improve patient care and prevent readmission to hospital. (Source: Heart and Lung)
Source: Heart and Lung - December 27, 2021 Category: Intensive Care Authors: Tara Whitmire Source Type: research

Clinical benefits in patients with home-based cardiac rehabilitation in the era of COVID-19 pandemic
I read the study by Jafri et al.1 with great interest. The authors evaluated outcomes of patients with or without home-based cardiac rehabilitation (HBCR). Although HBCR was significantly associated with a lower risk of the combined all-cause mortality and all-cause hospitalizations up to 12 months, the adjusted hazard ratios (95% confidence intervals) of HBCR for all-cause mortality, cardiovascular hospitalization, and all-cause hospitalization were 0.43 (0.18 –1.0), 0.57 (0.22–1.4), 0.53 (0.28–1.01), respectively. (Source: Heart and Lung)
Source: Heart and Lung - December 22, 2021 Category: Intensive Care Authors: Tomoyuki Kawada Tags: Letter Source Type: research

Advancing knowledge of self-care instruments
There is growing interest in self-care including those theory-based research instruments designed to measure self-care, such as the Self-Care of Heart Failure Index (SCHFI),1 the Self-Care of Chronic Illness Inventory (SC-CII),2 the Self-Care of Diabetes Inventory (SCODI),3 and the Self-Care of Chronic Obstructive Pulmonary Disease Inventory (SC-COPDI).4 All these instruments, and others available on the website, are based on the Middle-Range Theory of Self-Care of Chronic Illness,5 which provides a theoretical basis on which to develop and validate the self-care instruments of chronic diseas...
Source: Heart and Lung - December 16, 2021 Category: Intensive Care Authors: Maria Matarese, Claudio Barbaranelli, Barbara Riegel Source Type: research

A systematic review and metanalysis of diagnostic yield of BAL for detection of SARS-CoV-2
Microbiological confirmation by reverse transcriptase-polymerase chain reaction (RT-PCR) is considered the gold standard for diagnosing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection1. Oropharyngeal (OP) and nasopharyngeal swabs (NP) were most frequently used samples. While OP and NP swabs are the least invasive method of obtaining samples in patients with a contagious respiratory disease, false-negative results may result from sampling error or low amounts of virus in the collected sample (due to early or late sampling or patient having mild disease2). (Source: Heart and Lung)
Source: Heart and Lung - December 12, 2021 Category: Intensive Care Authors: Sumita Agrawal, Akhil Dhanesh Goel, Nitesh Gupta, Hari Kishan Gonuguntla, Henri Colt Source Type: research

Should I stay or should I go? An exploration of the decision-making behaviour of acute cardiac patients during the COVID-19 pandemic
Internationally, the COVID-19 pandemic has resulted in a substantial increase in excess mortality from non COVID-19 conditions1. Many countries have imposed social containment mandates ( ‘lockdowns’), to reduce population movement, as a result emergency attendances at hospital have considerably reduced (37%)2. Such approaches are designed to reduce a surge in capacity allowing the management of acute and critically ill COVID-19 patients. Nevertheless, this strategy appears to ha ve deterred the most seriously ill non COVID-19 patients from seeking medical help. (Source: Heart and Lung)
Source: Heart and Lung - November 15, 2021 Category: Intensive Care Authors: S. Burton, J.A. Hayes, N. Morrell-Scott, J. Sanders, H. Walthall, D.J. Wright, I. Jones Source Type: research

A new year, a new resolution: nurses impacting america's health debt from the covid-19 pandemic
It is likely many will begin this New Year with some trepidation and skepticism as the past two years have been driven by crisis and chaos from the COVID-19 pandemic. The pandemic has exacerbated disparities that have existed for many generations and while we have been aware of these social determinants of health: low-income individuals, older adults, those living in rural areas and people of color; COVID-19 has disproportionately impacted these historically marginalized communities. The subsequent health debt as well as the accumulation of the impact of changes in health behaviors during the pandemic will have a long-last...
Source: Heart and Lung - November 1, 2021 Category: Intensive Care Authors: Ashley Moore-Gibbs Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - October 19, 2021 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - October 19, 2021 Category: Intensive Care Source Type: research

COVID-19 Suspected Myopericarditis without Pulmonary Involvement
We report a case of a young African American man presenting with myopericarditis following a recently recovered COVID-19 infection. Complicated by ICU admission requiring vasopressors; with eventual resolution following initiation of aspirin and colchicine for myopericarditis.Life threatening myopericarditis can occur following resolution of COVID-19 disease. (Source: Heart and Lung)
Source: Heart and Lung - October 9, 2021 Category: Intensive Care Authors: Steven Mirabella, Oshin Bansode, Hyfaa Mashaal, Jagadish Akella Source Type: research

AAHFN Leadership Message for Heart and Lung Journal
The health of those around the globe was significantly impacted in 2020. The Stress in AmericaTM survey conducted by Harris Poll for the American Psychology Association in October 2020 identified most participants experienced altered physical and emotional wellbeing. Of those surveyed, sixty-one percent of adults reported unplanned weight changes with an average reported weight gain of 29 pounds since the COVID-19 pandemic began. Delayed healthcare, depression, and changes in sleep and alcohol habits were a few of the areas negatively affected1. (Source: Heart and Lung)
Source: Heart and Lung - September 24, 2021 Category: Intensive Care Authors: Dr. Kimberly Nelson Source Type: research

Patient names for mechanical circulatory support devices: Developing emotional insights
Previous work1 –6 has addressed psychosocial considerations in the prescription and management of Mechanical Circulatory Support (MCS) for patients with heart failure (HF). Here, MCS as a category includes ventricular assist devices and total artificial hearts. The systems comprise an implantable mechanical pump , and external peripherals in the form of a control unit and batteries.7 Understandably, psychosocial factors have mostly been explored from a clinical perspective regarding their implications for MCS treatment candidacy,8 compliance,9 palliative decision-making,4 and formal mental health interventi ons. (Source: Heart and Lung)
Source: Heart and Lung - August 23, 2021 Category: Intensive Care Authors: Prof. Cara Wrigley, Dr. Sean Peel, Kimmi Keum Hee Ko, Dr. Karla Straker Source Type: research

Frailty Assessment in Heart Failure and Ventricular Assist Device Populations: A Review from the United States
There are currently 960,000 new individuals diagnosed with heart failure with reduced ejection fraction (HFrEF) annually, pushing HFrEF prevalence to epidemic proportions with an estimated 8 million individuals diagnosed with HFrEF by 2030.1 Even more alarming, nearly half of individuals diagnosed with HFrEF will die within five years of diagnosis.2 Higher morbidity and mortality are reported in frail populations undergoing cardiovascular surgical procedures.3 Implantation of a durable left ventricular assist device (dLVAD) is a major cardiovascular surgical procedure, so it is paramount for clinicians to recognize and und...
Source: Heart and Lung - August 22, 2021 Category: Intensive Care Authors: Sarah E. Schroeder, Bunny J. Pozehl, Windy W. Alonso Source Type: research

Hypoglycemia and mortality in sepsis patients: A systematic review  and meta-analysis
Sepsis is one of the main causes of death across the world, and it is also the most familiar cause of death among intensive care unit (ICU) patients,1 Sepsis-related mortality rate ranges from 15% to 56%.2 Patients with sepsis often have varying degrees of blood glucose level disorders due to changes in their endocrine metabolism, which affects the stability of the internal environment and aggravates the patient's condition. (Source: Heart and Lung)
Source: Heart and Lung - August 22, 2021 Category: Intensive Care Authors: Jing Wang, Cheng-Kai Zhu, Jiang-Quan Yu, Rui Tan, Peng-Lei Yang Source Type: research

The effects of rational emotive behavior therapy for depressive symptoms in adults with congenital heart disease
Although the number of adults with Congenital Heart Disease (CHD) has grown dramatically due to advances in cardiac surgery and medical technology,1,2 most patients still struggle with lifelong illness due to residual sequelae and complications from the underlying heart disease.2,3 Adults with CHD, which is chronic, also face psychological challenges, which may manifest as emotional distress, including depression, due to loneliness and isolation, fear of negative evaluation, imposed limits, low capacity for physical exercise, perceived health status, and feelings of alienation, marginalization, and disempowerment. (Source: Heart and Lung)
Source: Heart and Lung - August 17, 2021 Category: Intensive Care Authors: Ju Ryoung Moon, June Huh, Jinyoung Song, I-Seok Kang, Seung Woo Park, Sung-A Chang, Ji-Hyuk Yang, Tae-Gook Jun, Jong-Sook Han Source Type: research

Correlation of blood high mobility group box-1 protein with mortality of patients with sepsis: A meta-analysis
Sepsis, defined as a life-threatening organ dysfunction attributable to a dysregulated host response to infection,1 remains a major cause of death in the intensive care unit (ICU) and a critical consumer for medical resources around the world, along with its associated illnesses. According to a global study, there were an estimated 11.0 million incident cases of sepsis-related mortality worldwide in 2017, representing about 19.7% of all global deaths.2 To promptly identify sepsis patients at higher risks of mortality and optimize treatment options, such risk-stratified systems as Sequential Organ Failure Assessment (SOFA) ...
Source: Heart and Lung - August 16, 2021 Category: Intensive Care Authors: Jingjing Cai, Zhuandi Lin Source Type: research

The relationship of the geriatric nutritional risk index to mortality and length of stay in elderly patients with acute respiratory failure: A retrospective cohort study
Acute respiratory failure (ARF) is characterized by arterial oxygen tension (PaO2) 45 mm Hg.1 Approximately 30% of all admissions to intensive care unit (ICU) are critically ill ARF patients.2 Elderly patients with ARF have higher hospital mortality (32.4 versus 20.6%) and longer hospital length of stay (LOS) compared with younger patients, (13 days versus 7.1 days).3–5 In the USA, ARF treatment cost exceeds $50 billion per year due to the high mortality and long LOS, especially for elderly patients. (Source: Heart and Lung)
Source: Heart and Lung - August 16, 2021 Category: Intensive Care Authors: Xiawei Shi, Yueqian Shen, Jia Yang, Wurong Du, Junchao Yang Source Type: research

A pilot randomized clinical trial of a teamwork intervention for heart failure care dyads
The prevalence of heart failure (HF) in the United States is increasing with approximately 6.2 million Americans currently living with HF.1 These individuals are recommended to follow a complex self-management regimen and rarely assume self-management alone.2 Moreover, the trajectory of illness is highly variable and most persons with HF remain in the community through the advanced stages of their disease while receiving assistance from their family caregivers.3 The central role of family caregivers in the management of HF has been well documented in the literature. (Source: Heart and Lung)
Source: Heart and Lung - August 15, 2021 Category: Intensive Care Authors: Elliane Irani, Atsadaporn Niyomyart, Mary A. Dolansky, John Paul Stephens, Stephen J. Ganocy, Richard A. Josephson, Ronald L. Hickman Source Type: research

The effect of Shiatsu massage on agitation in mechanically ventilated patients: A randomized controlled trial
A large number of patients are admitted to the Intensive Care Units (ICUs) every year, some of which require mechanical ventilation due to the nature of their conditions.1 Mechanical ventilation is a life-saving intervention used worldwide, and it is a key component of caring for critically ill and severely traumatized patients and it could be used for many reasons, such as bradypnea and apnea following respiratory arrest, acute lung injury, Acute Respiratory Distress Syndrome (ARDS), tachypnea, pulmonary dysfunctions, blood gases and acid-base disorders, changes in patient's clinical condition, respiratory muscle fatigue,...
Source: Heart and Lung - August 15, 2021 Category: Intensive Care Authors: Mehdi Harorani, Masoumeh Garshasbi, Mohamad Sediqi, Zohreh Farahani, Danial Habibi, Mahtab Farahani, Nazanin Amini, Zahra Velashjerdi Source Type: research

A comparison of the hemodynamic effects of fluid bolus therapy with crystalloids vs. 4% albumin and vs. 20% albumin in patients after cardiac surgery
Crystalloid or colloid fluid bolus therapy (FBT) is common after cardiac sugery.1 Its rationale is based on the notion that FBT increases cardiac preload and, thereby, cardiac index (CI) and mean arterial pressure (MAP). (Source: Heart and Lung)
Source: Heart and Lung - August 14, 2021 Category: Intensive Care Authors: Fumitaka Yanase, Salvatore L Cutuli, Thummaporn Naorungroj, Laurent Bitker, Anthony Wilson, Glenn M Eastwood, Rinaldo Bellomo Source Type: research

Providers ’ assignment of NYHA functional class in patients with heart failure: A vignette study
Heart failure (HF) is a major public health problem. It is estimated that the prevalence of HF will increase by 46% resulting in more than 8 million adults>18 years of age by the year of 2030 having HF.1 Heart failure is a costly condition for the U.S. with the burden of complex and repeated hospitalization for the exacerbation of HF and the co-occurring comorbidities.2 It leads to more hospitalizations and death than cancer and although the mortality rate of those with HF has improved since the 1970s those who are diagnosed with HF today still have a 50% chance of dying within 5 years of diagnosis. (Source: Heart and Lung)
Source: Heart and Lung - August 14, 2021 Category: Intensive Care Authors: Kelly D. Stamp, Marilyn A. Prasun, Thomas P. McCoy, Lisa Rathman Source Type: research

Changing the model of care during the COVID-19 pandemic: Same-day discharge of patients undergoing elective invasive cardiac procedures in Hong Kong
Percutaneous coronary intervention (PCI) is recommended as the treatment-of-choice for patients with acute coronary syndrome and stable coronary artery disease with persistent symptoms despite optimal medical therapy.1 While coronary artery disease is a highly prevalent condition and the leading contributor to the global disease burden,2,3 PCI has become one of the most frequently performed medical procedures globally. Historically, overnight observation is the standard of care for patients who have undergone PCI, to observe and treat for potentially serious complications, such as stent thrombosis, myocardial ischemia, acc...
Source: Heart and Lung - August 8, 2021 Category: Intensive Care Authors: Cecilia Miu-Ching CHAN, Michael Kang-Yin LEE, Alan Ka-Chun CHAN, Man Ling HUI, Polly Wai Chi LI Source Type: research

The Lived Experiences of Family Members of Covid-19 Patients Admitted to Intensive Care Unit: A Phenomenological Study
The health and economic impact of the Coronavirus Disease 2019 (COVID-19) pandemic continues to expand worldwide, highlighting the strengths and weaknesses of our health systems, political institutions, media, and economies.1 COVID-19 was identified for the first time in Wuhan, China, in December 2019. Since then, the entire world has experienced COVID's rapid spread, and the World Health Organization (WHO) declared Sars-CoV-2 a pandemic emergency.2 On March 31, 2021, there were 128 million confirmed COVID-19 cases, including 2.81 million deaths; Europe had 45.11 million confirmed cases. (Source: Heart and Lung)
Source: Heart and Lung - August 6, 2021 Category: Intensive Care Authors: Davide Bartoli, Francesca Trotta, Silvio Simeone, Gianluca Pucciarelli, Giovanni Battista Orsi, Oriana Acampora, Marco Di Muzio, Carmen Cappitella, Monica Rocco Source Type: research

Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - August 4, 2021 Category: Intensive Care Source Type: research

Board of Directors
(Source: Heart and Lung)
Source: Heart and Lung - August 4, 2021 Category: Intensive Care Source Type: research

Participation self-efficacy plays a mediation role in the association between mobility and social participation among stroke survivors
Mobility is a major determinant of social participation after stroke and the relationship between the two may be mediated by participation self-efficacy. (Source: Heart and Lung)
Source: Heart and Lung - August 2, 2021 Category: Intensive Care Authors: Janita Pak Chun Chau, Suzanne Hoi Shan Lo, Kai Chow Choi, Laveeza Butt, Jie Zhao, David R. Thompson Source Type: research

Association of N-terminal pro-brain natriuretic peptide level with adverse outcomes in patients with acute myocardial infarction: A meta-analysis
Despite progress in reperfusion therapy, acute myocardial infarction (AMI) is still a leading cause of morbidity and death worldwide.1 Based on the electrocardiogram change, AMI can be grouped into ST-segment elevation myocardial infarction (STEMI) and non –ST-segment elevation myocardial infarction (NSTEMI). Survivors of AMI are at high risk of cardiovascular events and death than the general population.2 Incidence of in-hospital and 1-year death after STEMI was approximately 5 to 6% and 7 to 18%. (Source: Heart and Lung)
Source: Heart and Lung - August 2, 2021 Category: Intensive Care Authors: Shenghui Shen, Jianhua Ye, Xiangzhong Wu, Xiaoling Li Source Type: research

Deceleration capacity is associated with acute respiratory distress syndrome in COVID-19
The current worldwide pandemic of the 2019 coronavirus disease (COVID-19) caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) poses a significant threat to global health and economy. The clinical presentation varies widely among individuals from mild afebrile respiratory symptoms to severe illness causing acute respiratory distress syndrome (ARDS).1 Approximately 5% of infected persons require admission to an intensive care unit and approximately 12% of hospitalized COVID-19 persons receive mechanical ventilation. (Source: Heart and Lung)
Source: Heart and Lung - August 2, 2021 Category: Intensive Care Authors: Lars Mizera, Dominik Rath, Anna Schoellmann, Alvaro Petersen-Uribe, Alban Avdiu, Monika Zdanyte, Philippa Jaeger, David Heinzmann, Karin M üller, Meinrad Gawaz, Christian Eick, Martin Duckheim Source Type: research

The serial connection of two extracorporeal membrane oxygenators for patient with refractory hypoxemia
It is very important to know what additional strategies to apply to patients when severe hypoxemia or hypercapnia does not improve even with VV ECMO support. Changing ventilator settings, catheter repositioning, prone positioning and ECMO flow are important measures to improve hypoxemia and/or hypercapnia during VV ECMO support.1 However, these methods may not be effective if, for some reasons including trauma, sepsis, or other systemic inflammatory responses, the patient needs more blood flow or oxygen delivery than the maximum flow or oxygen delivery of the ECMO. (Source: Heart and Lung)
Source: Heart and Lung - July 27, 2021 Category: Intensive Care Authors: Dong Hoon Kang, Jong Woo Kim, Sung Hwan Kim, Seong Ho Moon, Jun Ho Yang, Jae Jun Jung, Ho Jeong Cha, Jun Young Choi, Chung Eun Lee, Won Heo, Sung Dae Lim, Joung Hun Byun Source Type: research

Gender differences in psychosocial and clinical characteristics in the European Registry for Patients with Mechanical Circulatory Support
Mechanical circulatory support (MCS) devices are well-established treatments for advanced heart failure (HF) in Europe and in the United States (US).1,2 The representation of women among MCS recipients is low on both continents, with (Source: Heart and Lung)
Source: Heart and Lung - July 26, 2021 Category: Intensive Care Authors: Sarah L öchel, Lisa-Marie Maukel, Gerdi Weidner, Theo M.M.H. de By, Heike Spaderna Source Type: research

Can optoelectronic plethysmography be used to evaluate the thoracoabdominal kinematics of people with morbidly obesity? A systematic review
Obesity is characterized by an increase in adipose tissue in the body and consequent excess of the body weight. The prevalence of obesity has increased worldwide and the disease affects approximately 39% of the adult world population.1 Obesity is a risk factor for several other diseases, comorbidities or functional changes, including changes in respiratory mechanics.2 (Source: Heart and Lung)
Source: Heart and Lung - July 26, 2021 Category: Intensive Care Authors: Joaquim Henrique Lorenzetti Branco, Ruy Luiz Lorenzetti Branco, Vicente Paulo Ponte Souza Filho, Bruna da Silveira, Kethlyn Tamara Monteiro Pause, Regiana dos Santos Artismo, Darlan Laur ício Matte Source Type: research

Clinical and economic outcomes associated with hospitalizations for acute idiopathic pericarditis in the United States
In developed nations such as the United States (U.S.), acute pericarditis often involves idiopathic or presumed viral etiologies.1-6 Many patients diagnosed with acute idiopathic pericarditis (AIP) are admitted for management and may be treated for or experience pericarditis-related complications in the hospital.1-6 Treatment of complications and sequelae of AIP may involve more complex interventions, including procedural management such as pericardiocentesis, pericardial window, pericardiotomy, and/or surgical intervention with pericardiectomy. (Source: Heart and Lung)
Source: Heart and Lung - July 23, 2021 Category: Intensive Care Authors: Nicholas C. Schwier, Nicole T. Tran, Grant H. Skrepnek Source Type: research

Age and gender differences in physical heart failure symptom clusters
Heart failure (HF), a global clinical condition affecting 26 million around the world, is characterized by significant rates of costly hospitalizations.1,2 Due to improvements in the use of guideline directed medical therapy, mortality rates from HF have declined but prevalence and associated morbidity continue to rise.1 Physical HF symptoms are important early indicators of impending decompensation and the most common reason for seeking care making them an important focus of study3. Most HF hospitalizations are for management of distressing symptoms, especially dyspnea and fatigue, with over half of patients reporting any...
Source: Heart and Lung - July 23, 2021 Category: Intensive Care Authors: Kristen A. Sethares, Elizabeth Chin Source Type: research

Establishing a process to translate and adapt health education materials for natives and immigrants: The case of Mandarin adaptations of cardiac rehabilitation education
The growing burden of cardiovascular diseases (CVD) in China has rendered it a major public health issue, with 11 million people living with coronary artery disease (CAD).1 Moreover, consistent with overall increases in global migration, many Chinese people have resettled in Asian, but also Western, countries (e.g., Unites States, Canada);2 this renders control of CVD an issue for Chinese people elsewhere as well. Indeed, in 2019, Chinese-born migrants were the third largest foreign-born population in the world, with nearly 11 million people living outside of China. (Source: Heart and Lung)
Source: Heart and Lung - July 4, 2021 Category: Intensive Care Authors: Xia Liu, Gabriela L.M. Ghisi, Shu Meng, Sherry L. Grace, Wendan Shi, Ling Zhang, Robyn Gallagher, Paul Oh, Crystal Aultman, Nicole Sandison, Biao Ding, Yaqing Zhang Source Type: research

ECG alarms during left ventricular assist device (LVAD) therapy in the ICU
Alarm safety is a Hospital Based National Patient Safety Goal established by The Joint Commission in 2014.1 In the hospital setting, clinical alarm systems used in bedside monitors are designed to alert busy caregivers about a change in a patient's condition to avert adverse events. While this is the goal of clinical alarms, previous research shows that patients in the intensive care unit (ICU) yield high numbers of false and nonactionable alarms (i.e. true alarms but no action needed) creating an environment for alarm fatigue. (Source: Heart and Lung)
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Kevin Watanakeeree, Sukardi Suba, Lynda A. Mackin, Fabio Badilini, Michele M. Pelter Source Type: research

A novel phonetic approach to continuous flow left ventricular assist device auscultation
With approximately 3000 new continuous flow left ventricular assist device (cf-LVAD) implants in the U.S. annually, clinical providers within a multitude of subspecialties of medicine are now faced with the multi-disciplinary care of these people both in-person or via tele-medicine.1 Although intimidating, it is important for providers to become familiar with the unique physical examination features of these devices. The dominant sound generated by cf-LVADs has generically been referred to (and taught) as a “hum”. (Source: Heart and Lung)
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Faris G. Araj, Julie Cox, Alpesh A. Amin, Pradeep P.A. Mammen Source Type: research

Pain intensity and pain medication prescription patterns in Veterans with heart failure and back pain
Heart failure (HF) is a complex chronic health condition characterized by multiple symptoms and comorbidities. It affects approximately 26 million people worldwide contributing to significant economic burden.1 Comorbid conditions are often experienced by those with HF, including chronic pain due to illness or injury. For example, one study found that 84.4% of patients with advanced HF reported pain, with 76% reporting non-chest pain.2 Furthermore, chronic pain is associated with pain interference (e.g., pain that interferes with activities of daily living),3 which can limit the ability of these patients to engage in critic...
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Casey E. Cavanagh, Lindsey Rosman, Philip W. Chui, Eric DeRycke, Harini Bathulapalli, Parul Gandhi, Lori A. Bastian, Matthew M. Burg, Cynthia Brandt, Joseph L. Goulet Source Type: research

Dynamic factor analysis of seasonal variation in daily physical activity in individuals with heart failure and implanted cardiac devices
In individuals with heart failure (HF), daily physical activity (PA) is associated with many important clinical endpoints including actual and predicted mortality risk,1 –4 aerobic capacity,1 health-related quality of life,5–7 sympathetic nervous system activity,8,9 hospitalization10–13 and ability to participate in activities of daily living.5–7 Additionally, amount of sedentary time is a better predictor of HF-related prognosis and mortality than is exerci se testing.4 Improving daily PA is therefore an important clinical outcome. (Source: Heart and Lung)
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Michael J. Shoemaker, Andrew Kampfschulte, Sarah Rustmann, Michael G. Dickinson Source Type: research

Post-traumatic stress disorder symptoms after veno-arterial extracorporeal membrane oxygenator support
Post-intensive care syndrome includes cognitive and psychological impairment such as post-traumatic stress disorder (PTSD). PTSD includes intrusion, avoidance and hyperarousal symptoms, with functional impairment, after the exposure to a stressor.1 Intrusion symptoms consist in re-experiencing the traumatic event including nightmares and flashbacks, avoidance entails efforts to separate from situations, places, and people that are reminders of the stressor and hyperarousal includes irritability, concentration problems and sleep disturbances. (Source: Heart and Lung)
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Marta Alonso-Fernandez-Gatta, Miryam Gonzalez-Cebrian, Soraya Merchan-Gomez, Ines Toranzo-Nieto, Alejandro Diego-Nieto, Pedro L. Sanchez Source Type: research

Exploring experiences of hypertrophic cardiomyopathy diagnosis, treatment, and impacts on quality of life among middle-aged and older adults: An interview study
Hypertrophic cardiomyopathy (HCM) is the most common genetic disorder of the heart, with prevalence estimates ranging from 1 in 500 individuals1 to 1 in 200 individuals2 in the general adult population. HCM is a clinically and genetically heterogeneous disorder and an important cause of sudden death and heart failure. Early diagnosis of HCM is associated with a greater likelihood of receiving appropriate treatment to improve symptoms and reduce risk of adverse outcomes, initiation of lifelong clinical surveillance, identification of underlying genetic etiologies, and counseling and screening of family members at risk of HC...
Source: Heart and Lung - July 2, 2021 Category: Intensive Care Authors: Deena Zytnick, Debbie Heard, Ferhaan Ahmad, Sharon Cresci, Anjali Tiku Owens, Christina M. Shay Source Type: research

Feasibility of a virtual reality intervention in the intensive care unit
Intensive care unit (ICU) delirium affects 45% to 87% of critically ill patients1,2 and is independently associated with an increased risk of long-term cognitive decline and increased health care costs.3 In the ICU setting, factors such as immobility, sensory impairment, pain, and agitation are thought to increase the risk of delirium.4 Critically ill patients commonly receive analgesics and sedatives for management of pain and anxiety,5,6 and these medicines themselves are associated with an increased risk of delirium. (Source: Heart and Lung)
Source: Heart and Lung - July 1, 2021 Category: Intensive Care Authors: Yameena T. Jawed, Dmitriy Golovyan, David Lopez, Sikandar H. Khan, Sophia Wang, Chauncey Freund, Sundus Imran, Usman Bin Hameed, Joseph P. Smith, Lotte Kok, Babar A. Khan Source Type: research

Dissociation between the clinical course and chest imaging in severe COVID-19 pneumonia: a series of five cases
Our results suggest that in cases of clinical improvement with worsened or stable chest imaging variables, the PaO2:FiO2 ratio might be a good marker of the resolution of COVID-19-specific pulmonary vascular insult. (Source: Heart and Lung)
Source: Heart and Lung - June 29, 2021 Category: Intensive Care Authors: Damien Basille, Marie-Anne Auquier, Claire Andr éjak, Daniel Oscar Rodenstein, Yazine Mahjoub, Vincent Jounieaux, A & P Group Source Type: research

Heart and Lung Leadership Message for September/October 2021An Ounce of Protection is a Pound of Prevention
There are several health and heart failure themes I would like to discuss in this message: influenza, SARS-CoV 2 and this year's focus on prevention. We've had a proactive focus on heart failure prevention this year, but as we move into the fall season in the US, I think it is relevant to think about the upcoming influenza season for 2021-2022, and how prevention is key. It is well documented that worse outcomes from influenza occur in those with cardiovascular disease.1 Whether we are talking about COVID-19 vaccination or influenza vaccination, we know that these measures are extremely important to control disease and imp...
Source: Heart and Lung - June 23, 2021 Category: Intensive Care Authors: Craig Thomas Source Type: research

Heart and Lung Leadership message for September/October 2021
An Ounce of Protection is a Pound of Prevention (Source: Heart and Lung)
Source: Heart and Lung - June 23, 2021 Category: Intensive Care Authors: Craig Thomas Source Type: research