Severe sleep apnea as a predictor of failure to respond to cardiac resynchronization therapy
Sleep-disordered breathing (SDB) of at least moderate severity with an apnea-hypopnea index (AHI) of ≥15 events per hour (events/h) is found in approximately 50% of patients with congestive heart failure (CHF) and more often in case of men.1,2,3 The risk of developing SDB in this population increases by 10% for every 5% reduction in left ventricular ejection fraction (LVEF).1 Their occurrence is favored by low cardiac output (CO) with a prolonged circulatory delay and unstable ventilatory control during sleep, as well as increased left ventricular (LV) filling pressure and pulmonary congestion. (Source: Heart and Lung)
Source: Heart and Lung - February 16, 2023 Category: Intensive Care Authors: Danuta Łoboda, Jacek Wilczek, Karolina Simionescu, Jolanta Biernat, Tomasz Jadczyk, Wojciech Wojakowski, Krzysztof S. Gołba Source Type: research
Barriers and facilitators to the adoption of digital health interventions for COPD management: A scoping review
Globally, chronic obstructive pulmonary disease (COPD) is a leading cause of death of morbidity and mortality.1 Characterized by persistent respiratory symptoms and airflow limitation, COPD is a chronic disease that can be largely prevented and treated.2 Yet, COPD accounts for a substantial economic and social burden that is set to increase in the coming years.2 Evidently, improved quality care services that reduce burden and costs are needed. (Source: Heart and Lung)
Source: Heart and Lung - February 16, 2023 Category: Intensive Care Authors: Hadassah Joann Ramachandran, Joo Lin Oh, Yue Krystal Cheong, Ying Jiang, Jun Yi Claire Teo, Chuen Wei Alvin Seah, Mingming Yu, Wenru Wang Source Type: research
SGLT2 inhibitors for prevention of primary and secondary cardiovascular outcomes: A meta-analysis of randomized controlled trials
Sodium-glucose cotransporter 2 inhibitors (SGLT2i) are novel glucose-lowering drugs that reduce renal resorption of glucose and increase glucose excretion in the urine, lowering blood glucose concentrations. The drugs work by decreasing the affinity for glucose of renal proximal tubular sodium-glucose cotransporter 2 (SGLT2).1-3 The hypoglycemic mechanism of SGLT2i includes an osmotic diuretic effect which lowers plasma volume and blood pressure. The resulting reduction in ventricular load improves vascular structure and function which may account for the cardiovascular and renal benefits. (Source: Heart and Lung)
Source: Heart and Lung - February 16, 2023 Category: Intensive Care Authors: Guijun He, Guosu Yang, Xiaoyu Huang, Duan Luo, Chao Tang, Zhen Zhang Source Type: research
Comment on: Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia
To the Editor, (Source: Heart and Lung)
Source: Heart and Lung - February 16, 2023 Category: Intensive Care Authors: Jordan Llerena-Velastegui, Jose Villamarin-Corrales, Jennifer Cabrera-Beltran, Anthony Fernandez-Arcos Tags: Letter Source Type: research
The relationship between dyspnea-related kinesiophobia and physical activity in people with COPD: Cross-sectional survey and mediated moderation analysis
physical activity (Source: Heart and Lung)
Source: Heart and Lung - February 15, 2023 Category: Intensive Care Authors: Jingjing Wang, Chenxiao Bai, Zeyi Zhang, Ou Chen Source Type: research
Pulmonary function is associated with frailty, hospitalization and mortality in older people: 5-year follow-up
Frailty is an age-associated biological syndrome characterized by progressive deterioration of physical function that increases the risk of disability, hospitalization and mortality in older adults.1,2 Different tools to diagnose this syndrome have been proposed, such as the Frailty Phenotype (FP) and Frailty Trait Scale 5 (FTS5), both with similar predictive capacities.2 –4 (Source: Heart and Lung)
Source: Heart and Lung - February 14, 2023 Category: Intensive Care Authors: Walter Sep úlveda-Loyola, Jose A. Carnicero, Alejandro Álvarez-Bustos, Vanessa Suziane Probst, Francisco J. Garcia-Garcia, Leocadio Rodriguez-Mañas Source Type: research
Authors response to: Comment on “Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia”
We thank authors for comments1 on our recent article ‘Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia’2. Our responses are given below: (Source: Heart and Lung)
Source: Heart and Lung - February 12, 2023 Category: Intensive Care Authors: S Okan, F Okan, F Duran Y ücesoy Source Type: research
Characteristics of cardiopulmonary exercise test in tracheobronchial tuberculosis patients with central airway stenosis
Central airway stenosis is an uncommon disorder, the main causes of which include tumors, tracheal trauma, and tracheal infections. Tracheobronchial tuberculosis (TBTB) is the main cause of central airway stenosis in China because of the prevalence of TB, thus central airway stenosis is not a common disorder in developed countries.1,2 Indeed, TBTB is the most common cause of scarring airway stenosis in Chinese adults (77.8%).1 In Western countries, however, scarring airway stenosis generally results from intubation, tracheotomy, burn injuries, secondary healing after surgery, or trauma. (Source: Heart and Lung)
Source: Heart and Lung - February 9, 2023 Category: Intensive Care Authors: Lili Shui, Huyu Wang, Binbin Yang, Guotao Li, Yajuan Chen Source Type: research
Opioid usage after left ventricular assist device implantation: A single center retrospective analysis
Left ventricular assist device (LVAD) therapy for end-stage advanced heart failure patients is gaining greater acceptance nationally and implant volume continues to increase. Early landmark trials showed significant superiority with LVAD compared to medical management prompting this increase in LVAD implantation. Outcomes with LVAD implantation have continued to improve from 52% one-year survival in the 2001 REMATCH trial to 82.3% one-year survival in the 2020 STS INTE RMACS report.1,2 However, LVAD implantation is a time-intensive surgical procedure requiring sternotomy or thoracotomy approach, placement of drains, and ...
Source: Heart and Lung - February 9, 2023 Category: Intensive Care Authors: Sarah Schettle, Youssef Shahin, Shannon Dunlay, Richard Daly, Amy Glasgow, Elizabeth Habermann, John Stulak, Andrew Rosenbaum Source Type: research
Cardiovascular complications of COVID-19 vaccines: A review of case-report and case-series studies
The new coronavirus is known as "Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV2)", responsible for COVID-19 disease originated in China in 2019 and rapidly became a pandemic. Soon after vaccination was started and till now, 38 types of vaccines are approved in different countries1-3. The development of an effective vaccine against the SARS-CoV-2 virus that causes COVID-19 disease has been proven to be a vital tool in controlling the high pandemic's spread and its enormous effects4. Multiple coronavirus vaccines are currently being developed, including the mRNA-1273 (Moderna), mRNA vaccines BNT162b2 (Pfizer-Bio...
Source: Heart and Lung - February 7, 2023 Category: Intensive Care Authors: Mohammad Hossein Paknahad, Fatereh Baharlouei Yancheshmeh, Azam Soleimani Source Type: research
Simplified Geleijnse score for identifying chest pain features associated with coronary ischemia
Currently, there are multiple risk scores to determine the prognosis of high-risk patients presenting with an acute coronary syndrome (ACS) to chest pain units or emergency departments. For example, the PURSUIT score predicts the risk of death or death/myocardial infarction (MI) at 30-days after admission in patients with unstable angina and non-ST elevation MI, the TIMI risk score estimates mortality for patients with unstable angina and non-ST elevation MI, and GRACE score predicts mortality among ACS patients. (Source: Heart and Lung)
Source: Heart and Lung - February 3, 2023 Category: Intensive Care Authors: Wern Yew Ding, Ana Isabel Romero-Aniorte, Antonio Tello-Montoliu, Pablo Gil-P érez, Cecilia López-García, Andrea Veliz-Martínez, Miriam Quintana-Giner, Gregory Y.H. Lip, José Miguel Rivera-Caravaca, Francisco Marín Source Type: research
Cardiovascular manifestations of monkeypox virus outbreak: An overview of the reported cases
Monkeypox (Mpox) is a zoonotic DNA virus related to the orthopoxvirus family that causes also smallpox infection, and is first diagnosed in humans in 1970.1 From the beginning of 2022, more than 70,000 cases were reported of Mpox infection in more than 50 countries, prompting the world health organization (WHO) to declare it as a public health concern.2,3 (Source: Heart and Lung)
Source: Heart and Lung - February 3, 2023 Category: Intensive Care Authors: Amr Ehab El-Qushayri, Abdelrahman G. Tawfik, Hani Mahmoud-Elsayed Source Type: research
Comment on: Evaluation of pulmonary function and exercise capacity after COVID-19 pneumonia
Letter: (Source: Heart and Lung)
Source: Heart and Lung - February 2, 2023 Category: Intensive Care Authors: Hamza Islam, Rabia Islam Tags: Letter to the editor Source Type: research
Metabolomic, oxidative, and inflammatory responses to acute exercise in chronic obstructive pulmonary disease
The loss of muscle mass, respiratory and peripheral muscle dysfunction, exercise intolerance, and reduced quality of life are important consequences of chronic obstructive pulmonary disease (COPD).1 (Source: Heart and Lung)
Source: Heart and Lung - January 30, 2023 Category: Intensive Care Authors: Aslihan Cakmak, Emirhan Nemutlu, Samiye Yabanoglu-Ciftci, Ipek Baysal, Elif Kocaaga, Lutfi Coplu, Deniz Inal-Ince Source Type: research
Nurse-led heart failure educational interventions for patient and informal caregiver dyads: An integrative review
Over 6.5 million individuals in the United States are currently diagnosed with heart failure (HF), with projected prevalence rates to increase by 46% in 2030.1,2 While advancements in treatments and devices for HF patients have improved the life span, they have increased the complexity of medical regimens for the aging population and their caregivers.3 Patients with HF often need assistance with complex daily HF pharmacological and non-pharmacological regimens to decrease the burden of disease.4 Many times, individuals with HF struggle to recognize early symptoms of worsening failure (e.g., bilateral lower extremity edema,...
Source: Heart and Lung - January 30, 2023 Category: Intensive Care Authors: Tamara L. Bernard, Breanna Hetland, Myra Schmaderer, Ronald Zolty, Bunny Pozehl Source Type: research
