Early passive orthostatic training prevents diaphragm atrophy and dysfunction in intensive care unit patients on mechanical ventilation: A retrospective case ‒control study
Intensive care unit (ICU) patients with a life-threatening disease are subsequently bedridden with prolonged immobilization to maintain medical stability.1 Mechanical ventilation (MV) is one of the most important life-supporting interventions to help ICU patients survive, with up to 40% of patients requiring MV.2 However, during the acute stage, prolonged physical inactivity and being bedridden due to MV negatively affect the neuromuscular and respiratory systems of most patients, leading to adverse unintended outcomes, such as muscle atrophy, restricted joint mobility,3 a reduced spontaneous breathing capacity, impaired l...
Source: Heart and Lung - January 27, 2023 Category: Intensive Care Authors: Xin-yu Gan, Jun Zhang, Ping Xu, Si-jin Liu, Zhi-lin Guo Source Type: research
Heart rate variability as a predictor of mechanical ventilation weaning outcomes
Mechanical ventilation (MV) is a critical mode of life support for patients with acute respiratory insufficiency, capable of totally or partially replacing spontaneous ventilation. Delays in the weaning process increase both mortality and intensive care unit (ICU) costs.1,2 It is estimated that 20% to 30% of patients have difficulties in the weaning process.3 (Source: Heart and Lung)
Source: Heart and Lung - January 26, 2023 Category: Intensive Care Authors: Renata Baltar da Silva, Victor Ribeiro Neves, Ulisses Ramos Montarroyos, Matheus Sobral Silveira, D ário Celestino Sobral Filho Source Type: research
Exercise and nutrition in critically ill patients-What is the correct formula?
ICU-acquired weakness is diagnosed in approximately 1 million mechanically ventilated patients annually.1 This weakness is secondary to multiple mechanisms including myopathy, neuropathy, deconditioning and protein malnutrition. In addition, ICU-acquired weakness is associated with decreased quality of life and increased mortality.2 Physical rehabilitation and nutritional support have the potential to improve muscle strength and help maintain functional status. (Source: Heart and Lung)
Source: Heart and Lung - January 24, 2023 Category: Intensive Care Authors: Margaret A. Pisani Source Type: research
Cerebral oxygenation during cardiopulmonary exercise testing in cardiorespiratory diseases: A systematic review
Cardiopulmonary exercise testing (CPET) is a well-supported assessment technique widely used around the world.1 CPET is an exercise test with concomitant gas exchange analysis, considered the gold standard for determining cardiorespiratory fitness and provides a comprehensive evaluation of the physiological responses involved in the exercise. The dynamic and non-invasive assessment of the integrated responses of the pulmonary, cardiovascular and skeletal muscle systems,1,2 to physical exercise provides relevant information for clinical decision making. (Source: Heart and Lung)
Source: Heart and Lung - January 18, 2023 Category: Intensive Care Authors: Gabriela Aguiar Mesquita Galdino, Patr ícia Rehder-Santos, Stephanie Nogueira Linares, Thomas Beltrame, Aparecida Maria Catai Source Type: research
Reduced Apela/APJ system expression in patients with pulmonary artery hypertension secondary to chronic obstructive pulmonary disease
Pulmonary artery hypertension (PAH) is a pathophysiological state involving abnormally elevated pulmonary artery pressure (PAP) caused by a variety of known and unknown causes. PAH is a common disease that poses a serious threat to human physical and mental health, however its etiology is not completely understood. At present, there are no curative treatments available for PAH. As a result, the prognosis is poor, and the mortality rate remains high.1 (Source: Heart and Lung)
Source: Heart and Lung - January 18, 2023 Category: Intensive Care Authors: Yuexin Hu, Yani Zong, Liangli Jin, Jue Zou, Zhi Wang Source Type: research
The affordable care act and do-not-resuscitate orders: Differences by race and ethnicity
The advance care planning (ACP) process can be effective in aligning patient preferences with medical care and result in higher quality end-of-life (EOL) care for the patient and greater levels of satisfaction without complicating grief for their loved ones.1,2 In addition to facilitating conversations with loved ones and medical providers about goals of care, the ACP process includes assigning a proxy to make decisions in case the patient becomes unable, and putting preferences into legal documents to ensure they are accurately followed. (Source: Heart and Lung)
Source: Heart and Lung - January 18, 2023 Category: Intensive Care Authors: Katherine Callahan, Yubraj Acharya, Christopher S. Hollenbeak Source Type: research
Author's response to: “Letter to the Editor: The atherogenic index of plasma as a predictor of mortality in patients with COVID-19”
This study was a study published in the early stages of the pandemic and was one of the first studies to express an opinion on this subject.1 Thank you again for your interest in the article. (Source: Heart and Lung)
Source: Heart and Lung - January 16, 2023 Category: Intensive Care Authors: Özge Turgay Yıldırım, Şeyhmus Kaya Source Type: research
Effect size estimates of risk factors for post-intensive care syndrome-family: A systematic review and meta-analysis
Families of patients admitted to intensive care units (ICU) often experience anxiety, depression, and post-traumatic stress disorder (PTSD) during patients ’ ICU stay and post-discharge.1–4 Moreover, families of people who die in the ICU experience a higher risk of developing prolonged grief disorder (PGD) and comorbid symptoms.5–7 The various mental health-related symptoms experienced by the families of ICU patients are termed “post-intensive care syndrome-family” (PICS-F), which comprises anxiety, depression, PTSD, and PGD. (Source: Heart and Lung)
Source: Heart and Lung - January 13, 2023 Category: Intensive Care Authors: Yoshiyasu Ito, Michihiro Tsubaki, Masahiro Kobayashi, Susumu Yagome, Yukihiro Sakaguchi Source Type: research
Association between ventilatory ratio and ICU mortality in interstitial lung disease patients on mechanical ventilation: A retrospective study
Interstitial lung disease (ILD) is a diverse group of diseases that causes fibrosis or inflammation of the pulmonary parenchyma, characterized by alveolar inflammation and interstitial fibrosis, and the main clinical manifestations include dyspnea, coughing, and hypoxemia.1 Although the group of diseases is complex and diverse and its etiology is mostly unknown, ILD has similar clinical characteristics, imaging findings, respiratory physiology, and pathophysiology. The prognosis of patients with ILD is poor, especially in critically ill patients requiring mechanical ventilation (MV), and the mortality rate is as high as 70...
Source: Heart and Lung - January 11, 2023 Category: Intensive Care Authors: Lin-Xi Fu, He Yu, Lan Lan, Feng-Ming Luo, Yue-Nan Ni Source Type: research
Comment on: Exercise capacity assessed with the one-minute sit-to-stand test (1-min STST) and echocardiographic findings in patients with heart failure with preserved ejection fraction (HFpEF)
I read the research by Christina Kronberger et al. entitled "Exercise capacity assessed with the one-minute sit-to-stand test (1-min STST) and echocardiographic findings in patients with heart failure with preserved ejection fraction (HFpEF)" with great enthusiasm. It was fortunate to read this work, and the author's efforts are to be applauded.1 We concur with the conclusion that the 1-min STST may have clinical value for clinicians in decision-making regarding follow-up visits and optimizing medical care. (Source: Heart and Lung)
Source: Heart and Lung - January 10, 2023 Category: Intensive Care Authors: Kamran Mahfooz, Syed Najeed Tags: Letter to the editor Source Type: research
Causal association between iron deficiency anemia and chronic obstructive pulmonary disease: A bidirectional two-sample Mendelian randomization study
Chronic obstructive pulmonary disease (COPD) is one of the leading causes of morbidity and mortality worldwide, with nearly 3 million people dying from the disease each year.1,2 China has a high population of patients with COPD, with a prevalence of 13.6% in people over the age of 40 years.3 This causes a great economic, social, and medical burden.4,5 In 2012, the Chinese Health and Welfare Commission included COPD as a key chronic disease for prevention and control.6 (Source: Heart and Lung)
Source: Heart and Lung - January 9, 2023 Category: Intensive Care Authors: Yi Wei, Lei Sun, Chao Liu, Lujia Li Source Type: research
Mortality rate in patients with SAR-COV-2 infection treated with extracorporeal membrane oxygenator: A systematic review and meta-analysis
At the end of 2019, the SAR-COV-2 pandemic emerged. Since then, the healthcare system has been strained with an enormous number of SAR-COV-2 infected cases. The virus is highly adaptive and contagious. The hospitals were flooded with severe pneumonitis and subsequently acute respiratory distress syndrome (ARDS).1 Various strategies have been used to provide respiratory care including nasal high flow oxygen cannula, prone position, and invasive mechanical ventilator.2 However, in extremely severe cases of ARDS, conventional mechanical ventilator support strategies could not reverse the hypoxia. (Source: Heart and Lung)
Source: Heart and Lung - January 6, 2023 Category: Intensive Care Authors: Toonchai Indrambarya, Mutita Chaichalothorn, Chayatat Sirinawin, Jule Namchaisiri, Paweena Susantitaphong Source Type: research
Endothelial function, arterial stiffness and heart rate variability of patients with cardiovascular diseases hospitalized due to COVID-19
Augmentation index (Source: Heart and Lung)
Source: Heart and Lung - January 1, 2023 Category: Intensive Care Authors: Cl áudia Regina da Silva Araújo, Juliana Fernandes, Débora Sidrônio Caetano, Ana Eugênia Vasconcelos do Rêgo Barros, Juliana Andrade Ferreira de Souza, Maria da Glória Rodrigues Machado, Maria Inês Remígio de Aguiar, Simone Cristina Soares Brand Source Type: research
Ambivalence is associated with decreased physical activity and cardiorespiratory fitness among adolescents with critical congenital heart disease
Adolescents with congenital heart disease (CHD) are less physically active than healthy peers,1 despite physical activity being safe and recommended for most in this population.2 Low physical activity engagement exacerbates heightened risk of future cardiovascular complications for adolescents with CHD.3 Thus, understanding factors that relate to physical activity among adolescents with CHD is vital for reducing the cardiovascular risk of this vulnerable population. (Source: Heart and Lung)
Source: Heart and Lung - December 30, 2022 Category: Intensive Care Authors: Kristen R. Fox, Steven P. Neville, Victoria R. Grant, Kathryn Vannatta, Jamie L. Jackson Source Type: research
IL-10-1082G/a gene polymorphism and the risk of acute lung injury/respiratory distress syndrome: Correspondence
Dear Editor, we would like to share ideas on the publication “The association of IL-10-1082G/A gene polymorphism with the risk of acute lung injury/respiratory distress syndrome (ALI/RDS): A meta-analysis.1” In order to determine the early warning signs of ALI/RDS, Yao et al. used the meta-analysis approach to clarify the association between SNP at the IL -10-1082G/A gene and susceptibility to ALI/RDS.1 Yao et al. came to the conclusion that SNP at the IL-10-1082G/A locus increased the risk of ALI/RDS, with genotype GG and allele G increasing the risk, particularly in Asia. (Source: Heart and Lung)
Source: Heart and Lung - December 30, 2022 Category: Intensive Care Authors: Rujittika Mungmunpuntipantip, Viroj Wiwanitkit Source Type: research
