Unsupervised machine learning identifies symptoms of indigestion as a predictor of acute decompensation and adverse cardiac events in patients with heart failure presenting to the emergency department
More than six million people in the United States have heart failure (HF).1 There are approximately one million incident cases diagnosed annually, and it is projected that the prevalence of HF will increase by 46% by 2030.2 Despite progressive advances in guideline-directed medical therapies, survival rates have leveled off over time, with the current 5-year mortality rate remaining as high as 42.3% −52.6%.3,4 In fact, HF is listed as a cause of death in approximately 13% of death certificates nationwide. (Source: Heart and Lung)
Source: Heart and Lung - May 27, 2023 Category: Intensive Care Authors: Karina Kraevsky-Phillips, Susan M. Sereika, Zeineb Bouzid, Gavin Hickey, Clifton W. Callaway, Samir Saba, Christian Martin-Gill, Salah S. Al-Zaiti Source Type: research
The gut-lung axis: Mendelian randomization identifies a causal association between inflammatory bowel disease and interstitial lung disease
Inflammatory bowel disease (IBD) is a chronic inflammatory disorder of the gastrointestinal system associated with genetic susceptibility, dysfunctional immune responses in the mucosa, and the imbalance in the intestinal microflora.1 Crohn's disease (CD) and ulcerative colitis (UC) are two subtypes of IBD. CD commonly affects the colon and the terminal ileum, which is mainly characterized by discontinuous and transmural inflammation and accompanied with thickening, narrowing, abscesses, fibrosis, and fistulas of the intestinal walls. (Source: Heart and Lung)
Source: Heart and Lung - May 27, 2023 Category: Intensive Care Authors: Qinghua Luo, Ping Zhou, Shuangqing Chang, Zhifang Huang, Yuan Zhu Source Type: research
Initial development of the chest pain conception questionnaire
Approximately 3% of adults in the U.S. have experienced acute coronary syndrome (ACS), and each year over 1 million adults in the United States will experience ACS or fatal coronary artery disease.1 Prompt care seeking for ACS improves outcomes for patients, as clinicians can intervene sooner, reducing potential myocardial damage and affording patients access to time limited therapies.2 However, to receive prompt treatment, patients must seek care quickly when ACS symptoms occur, yet delays in care seeking still exist in the United States. (Source: Heart and Lung)
Source: Heart and Lung - May 18, 2023 Category: Intensive Care Authors: John R. Blakeman, Ann L. Eckhardt, MyoungJin Kim Source Type: research
Comparison of Thrombotic and Clinical Outcomes in SARS-CoV-2-Pneumonia Versus Other Viral Pneumonia in an Urban Academic Medical Center
American Society of Hematology (Source: Heart and Lung)
Source: Heart and Lung - May 17, 2023 Category: Intensive Care Authors: Rachel Goldberg, William Ye, Kevin Johns, Jeffrey J. Mucksavage, Shvetha Dhandapani, John G. Quigley, Nancy L. Shapiro, Scott T. Benken, Eric Wenzler, Keri S. Kim Source Type: research
Implementation of a multidisciplinary inpatient heart failure service and its association with hospitalized patient outcomes: First experience from the Middle East and North Africa region
Guideline-directed medical therapy (Source: Heart and Lung)
Source: Heart and Lung - May 16, 2023 Category: Intensive Care Authors: Yosef Manla, Hussam H Ghalib, Firas Al Badarin, Richard Ferrer, Terrence Lee-St. John, Khalid Abdalla, Medhat Soliman, Guirgis Gabra, Feras Bader Source Type: research
Comparison of anticoagulation monitoring strategies for adults supported on extracorporeal membrane oxygenation: A systematic review
As an advanced life support device to temporarily assist patients' cardiopulmonary function, extracorporeal membrane oxygenation (ECMO) has been widely used and is effective in treating severe cardiopulmonary diseases.1,2 However, when in contact with an artificial surface, platelets are activated and inflammatory cytokines are simultaneously released, which together lead to a coagulation cascade.3,4 To avoid the occurrence of thrombotic events, systemic anticoagulation is recommended as one of the necessary preparations for ECMO. (Source: Heart and Lung)
Source: Heart and Lung - May 10, 2023 Category: Intensive Care Authors: Jinhe Sun, Yuteng Ma, Wanting Su, He Miao, Zhaotian Guo, Qianhui Chen, Yuzhong Zhang, Xiaochun Ma, Song Chen, Renyu Ding Source Type: research
Comment on: Effects of time of bed rest on vascular complications after cardiac catheterization in pediatric patients with congenital heart disease: A randomized controlled trial
To the Editor, (Source: Heart and Lung)
Source: Heart and Lung - May 9, 2023 Category: Intensive Care Authors: Muzainah Tabassum, Satesh Kumar, Tirath Patel Source Type: research
Impact of Risk for Severe COVID-19 Illness on Physical Activity during the Pandemic
The impact of the COVID-19 pandemic extends beyond direct infections to include health behaviors of people globally. Beginning in April 2020 policy makers in the United States began implementing recommendations; altering everyday life through lockdowns, physical distancing, mandated mask-wearing, continual testing, and vaccination policies.1 Guidelines and policies governing COVID-19-related behaviors were not always clear or implemented universally, leaving individuals to interpret a deluge of conflicting information. (Source: Heart and Lung)
Source: Heart and Lung - May 8, 2023 Category: Intensive Care Authors: Kelly L. Wierenga, Susan M. Perkins, Anna K. Forster, Jennifer Alwine, Susan Ofner, Malissa A. Mulkey, Eileen Danaher Hacker, Susan J. Pressler, Scott Emory Moore Source Type: research
Sex differences in the impact of physical frailty on outcomes in heart failure
Heart failure (HF) is a common cause of morbidity and mortality in the United States,1 particularly among older adults.2 There are over one million hospital admissions for HF annually,1 and readmission rates are around 50% by six months.3 HF is also associated with poor quality of life and greater symptom burden.4,5 As such, it is important to identify patients at high risk for poor outcomes. One prognostic indicator of poor outcomes in HF is frailty, a clinical syndrome defined as a biologic syndrome of reduced physiologic reserve that makes an individual more susceptible to the effects of stressors. (Source: Heart and Lung)
Source: Heart and Lung - May 6, 2023 Category: Intensive Care Authors: Sara H. Archer, Christopher S. Lee, Nandita Gupta, Mary Roberts Davis, Shirin O. Hiatt, Jonathan Q. Purnell, Deanne Tibbitts, Kerri Winters-Stone, Quin E. Denfeld Source Type: research
Predictors of participation in atrial fibrillation screening among community residents in China
Atrial fibrillation (AF) is the most common arrhythmia and affects 33.5 to 46.3 million people worldwide.1,2 China faces a similar challenge of AF burden. According to a national epidemiology study, at least 790 million adults aged 45 or older have been diagnosed with AF in China.3 An increase in the incidence and prevalence of AF is expected due to population aging, surging cardiovascular risk factors, and accumulating comorbidities (e.g., hypertension, diabetes, obesity).4 AF could increase the risk of stroke, and at least a quarter of ischemic stroke cases are caused by AF. (Source: Heart and Lung)
Source: Heart and Lung - May 6, 2023 Category: Intensive Care Authors: Haiyue Gu, Jun Huang, Shuqian Qiao, Xinyi Chen, Xi Cao Source Type: research
“Heart failure at either end of the spectrum”
It's been a little over a year since the new and improved guidelines for the management of heart failure were released.1 Significant changes in the treatment of both acute and chronic heart failure have occurred since 2017 when the last updates were released.2 Guideline directed medical therapy now includes four medication classes. New recommendations for heart failure with preserved ejection fraction now include the use of SGLT2i, MRAs and ARNi. Amyloid heart disease has been included, as well as recommendations for those patients whose left ventricular ejection fraction has improved to>40%. (Source: Heart and Lung)
Source: Heart and Lung - May 6, 2023 Category: Intensive Care Authors: Maureen Flattery Tags: Editorial Source Type: research
Cardiopulmonary outcomes following high flow nasal cannula in pediatric population: A systematic review
Hypoxia and dyspnea are the most common symptoms of heart failure in pediatric patients and represent the leading cause of emergency care in the pediatric emergency department.1 Respiratory support is the primary and most essential measure to be taken during emergency management of heart failure.2 A high-flow nasal cannula (HFNC) is a novel advancement in respiratory support therapy that allows two types of adjustments, precisely the rate of gas flow and the percentage of oxygen being delivered. (Source: Heart and Lung)
Source: Heart and Lung - May 4, 2023 Category: Intensive Care Authors: Rakan A. Alrzoq, Osama M. Alateeq, Maha S. Almslam, Fawaz A. Alanzi, Raghad T. Alhuthil Source Type: research
Feasibility of continuous non-invasive finger blood pressure monitoring in adult patients admitted to an intensive care unit: A retrospective cohort study
Hypotension is an everyday phenomenon in the intensive care unit (ICU).1 The reported incidences vary between 23% and 72%, depending on the definition used and ICU patient category studied.2 –5 Primarily retrospective evidence suggests an association between hypotension during ICU admission and an increased risk of morbidity and mortality.3,6–9 Continuous blood pressure (BP) monitoring ensures timely recognition and treatment of hypotensive events and is therefore often applied in t he ICU. The gold standard for continuous BP monitoring is through invasive arterial catheters. (Source: Heart and Lung)
Source: Heart and Lung - May 4, 2023 Category: Intensive Care Authors: Jaap Schuurmans, Arthur Rutger van Nieuw Amerongen, Lotte Elisabeth Terwindt, Jimmy Schenk, Denise Petra Veelo, Alexander Petrus Johannes Vlaar, Bj örn Jacob Petrus van der Ster Source Type: research
Does thiamine supplementation affect heart failure? A systematic review and meta-analysis of randomized control trials
Heart failure (HF) is a pathophysiological condition where decreased cardiac output is observed after any structural deformity or cessation of normal function.1 HF is considered a pandemic that has affected 64.3 million people worldwide as of 2017, subsequently being a global economic burden. Prevalence of HF varies according to the region where central Europe and the Middle East have the highest number of people (1133 –1196/10,000) experiencing HF as opposed to southeast Asia and eastern Europe, where HF is nearly half prevalent as its counterpart (595/10,000 people). (Source: Heart and Lung)
Source: Heart and Lung - April 30, 2023 Category: Intensive Care Authors: Abdul Rehman Shah Syed, Abdul Ahad Syed, Abdullah Akram, Muhammad Shaheryar Azam, Muhammad Ali Muzammil, Deepak, Ayesha Irshad Ansari, Farea Eqbal, Muhammad Haris Farooq, Mahima Khatri, Satesh Kumar, Nomesh Kumar Source Type: research
Table of Contents
(Source: Heart and Lung)
Source: Heart and Lung - April 29, 2023 Category: Intensive Care Source Type: research
