Sex differences in the impact of physical frailty on outcomes in heart failure

Heart failure (HF) is a common cause of morbidity and mortality in the United States,1 particularly among older adults.2 There are over one million hospital admissions for HF annually,1 and readmission rates are around 50% by six months.3 HF is also associated with poor quality of life and greater symptom burden.4,5 As such, it is important to identify patients at high risk for poor outcomes. One prognostic indicator of poor outcomes in HF is frailty, a clinical syndrome defined as a biologic syndrome of reduced physiologic reserve that makes an individual more susceptible to the effects of stressors.

Source: Heart and Lung - May 6, 2023 Category: Intensive Care Authors: Sara H. Archer, Christopher S. Lee, Nandita Gupta, Mary Roberts Davis, Shirin O. Hiatt, Jonathan Q. Purnell, Deanne Tibbitts, Kerri Winters-Stone, Quin E. Denfeld Source Type: research