Comparison of anticoagulation monitoring strategies for adults supported on extracorporeal membrane oxygenation: A systematic review

As an advanced life support device to temporarily assist patients' cardiopulmonary function, extracorporeal membrane oxygenation (ECMO) has been widely used and is effective in treating severe cardiopulmonary diseases.1,2 However, when in contact with an artificial surface, platelets are activated and inflammatory cytokines are simultaneously released, which together lead to a coagulation cascade.3,4 To avoid the occurrence of thrombotic events, systemic anticoagulation is recommended as one of the necessary preparations for ECMO.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research