Serum proteomic analysis in esophagectomy patients with postoperative delirium: A case-control study

Delirium, a type of an acute brain failure, is characterized by fluctuation in mental status, inattention, altered level of consciousness, and disorganized thinking. Postoperative delirium is highly prevalent, with rates ranging from 15-80%.1,2 Prior studies have found postoperative delirium rates as high as 50% among both cardiac and major noncardiac thoracic surgery patients.3 –7 Unfortunately, effective pharmacological interventions to treat or prevent delirium are not available, likely due to our limited understanding of delirium pathophysiology.

Source: Heart and Lung - September 23, 2023 Category: Intensive Care Authors: Sikandar H. Khan, Anthony J. Perkins, Samreen Jawaid, Sophia Wang, Heidi Lindroth, Rebecca E. Schmitt, Jason Doles, Jason D. True, Sujuan Gao, Gideon A. Caplan, Homer L. Twigg, Kenneth Kesler, Babar A. Khan Source Type: research