Efficacy and safety of fluticasone propionate/salmeterol and fluticasone propionate monotherapy in step-up treatment of childhood asthma: A systematic review and meta-analysis

Asthma, a heterogeneous respiratory disease, is characterized by chronic airway inflammation involving various cellular components such as eosinophils, mast cells, and neutrophils.1 Typical clinical symptoms consist of wheezing, shortness of breath, chest constriction, and coughing. This chronic respiratory disorder is characterized by reversible airway restriction and bronchial hyperreactivity.2,3 Asthma has emerged as one of the most prevalent noncommunicable chronic respiratory diseases affecting children, and its prevalence is rising consistently.
Source: Heart and Lung - Category: Intensive Care Authors: Source Type: research