Frontiers in cellular and infection microbiology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Erratum: Advances in application of CRISPR-Cas13a system
(Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

Characterization of a Straboviridae  phage vB_AbaM-SHI and its inhibition effect on biofilms of Acinetobacter baumannii
This study provided a new perspective into the potential application value of phage vB_AbaM-SHI as an antimicrobial agent. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

Toxoplasma gondii infection-induced host cellular DNA damage is strain-dependent and leads to the activation of the ATM-dependent homologous recombination pathway
In conclusion, current finding suggests that T. gondii infection affects the host cell genome integrity in a strain-dependent manner by causing DNA damage and chromosomal instability. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

Construction and validation of a machine learning model for the diagnosis of juvenile idiopathic arthritis based on fecal microbiota
ConclusionA JIA diagnosis model based on XGB algorithm was constructed with excellent performance, which may assist physicians in early detection of JIA patients and improve the prognosis of JIA patients. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

The effect of vitamin D deficiency on platelet parameters in patients with COVID-19
DiscussionThe aforementioned results imply that maintaining an elevated concentration of vitamin D in COVID-19 patients is important because it is associated with a decrease in MPV, which in turn reduces susceptibility to diseases such as coronary artery disease. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

A comparative study of genotyping and antimicrobial resistance between carbapenem-resistant Klebsiella pneumoniae and Acinetobacter baumannii isolates at a tertiary pediatric hospital in China
ConclusionsThese CRKP isolates exhibited different biological and genetic characteristics with dynamic changes, suggesting widespread communities. Continuous epidemiological surveillance and multicenter research should be carried out to strengthen the prevention and control of infections. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 8, 2024 Category: Microbiology Source Type: research

Antibiotic resistance of ESKAPE group-microorganisms in health institutions from Hermosillo and Ciudad Obreg ón, Sonora, México
IntroductionEnterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter spp. are microorganisms referred as the ESKAPE group pathogens. These microorganisms have generated great concern in health institutions around the world since most of them have resistance to multiple antibiotics and cause most infections associated with healthcare, as well as community infections. The aim of this study was the analysis of antibiotic resistance in microorganisms of the ESKAPE group, recovered from clinical samples in 11 health institutions from Hermosillo and Ciu...
Source: Frontiers in cellular and infection microbiology - March 7, 2024 Category: Microbiology Source Type: research

Erratum: Resistance against two lytic phage variants attenuates virulence and antibiotic resistance in Pseudomonas aeruginosa
(Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Editorial: Epidemiology of antimicrobial resistance and virulence factors of emerging and re-emerging bacteria
(Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Isolation and identification of Wickerhamiella tropicalis from blood culture by MALDI-MS
In this study, we isolated W. tropicalis from a blood sample of a six-year-old female with a history of B-cell precursor lymphoblastic leukemia in Japan in 2022. Though the strain was morphologically identified as Candida species by routine microbiological examinations, it was subsequently identified as W. tropicalis by sequencing the internal transcribed spacer (ITS) of ribosomal DNA (rDNA). The isolate had amino acid substitutions in ERG11 and FKS1 associated with azole and echinocandin resistance, respectively, in Candida species and showed intermediate-resistant to fluconazole and micafungin. The patient was successful...
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Signatures of disease outcome severity in the intestinal fungal and bacterial microbiome of COVID-19 patients
ConclusionsCOVID-19 was associated with opportunistic bacterial pathogens, and Candida was the dominant fungal taxon in the intestine. Together, we found an association between commensal SCFA-producers and a fungal genus that was present in the intestines of patients who did not experience the most severe outcome of the disease. We believe that this taxon could have played a role in the disease outcome, and that further studies should be conducted to understand the role of fungi in gastrointestinal and health protection. (Source: Frontiers in cellular and infection microbiology)
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

A comprehensive review of monkeypox virus and mpox characteristics
Monkeypox virus (MPXV) is the etiological agent of monkeypox (mpox), a zoonotic disease. MPXV is endemic in the forested regions of West and Central Africa, but the virus has recently spread globally, causing outbreaks in multiple non-endemic countries. In this paper, we review the characteristics of the virus, including its ecology, genomics, infection biology, and evolution. We estimate by phylogenomic molecular clock that the B.1 lineage responsible for the 2022 mpox outbreaks has been in circulation since 2016. We interrogate the host-virus interactions that modulate the virus infection biology, signal transduction, pa...
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Unveiling the antibacterial mechanism of resveratrol against Aeromonas hydrophila through proteomics analysis
This investigation delves into elucidating the mechanism by which resveratrol (Res), a natural polyterpenoid renowned for its antimicrobial properties, exerts its effects on Aeromonas hydrophila, a ubiquitous waterborne pathogen. Our findings underscore the dose-dependent manifestation of resveratrol in exhibiting antibacterial and antibiofilm formation activities against A. hydrophila. Employing a Data-independent acquisition (DIA) based quantitative proteomics methodology, we systematically compared differentially expressed proteins in A. hydrophila subjected to varying concentrations of Res. Subsequent bioinformatics an...
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Validating the inactivation of viral pathogens with a focus on SARS-CoV-2 to safely transfer samples from high-containment laboratories
This study established a validation strategy for virus inactivation. MethodsSARS-CoV-2 wild type, delta, and omicron variants underwent heat treatment at 95°C for 10 minutes using either a hot water bath or a thermocycler. To validate the inactivation process, heat-treated viruses, and untreated control samples were incubated with A549-hACE2 and Vero E6-TMPRSS2-T2A-ACE2 cells. The cells were monitored for up to 72 hours for any cytopathic effects, visually and under a microscope, and for virus genome replication via RT-qPCR. The quality of post-treated samples was assessed for suitability in downstream molecular testing a...
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research

Exploring the role of antioxidants in sepsis-associated oxidative stress: a comprehensive review
This article delves into the advantages and disadvantages associated with the utilization of antioxidants in the therapeutic approach to sepsis, which has been explored in a variety of animal models and clinical trials. While the application of antioxidants has been suggested as a potential therapy to suppress the immune response in cases where an intensified inflammatory reaction occurs, the use of multiple antioxidant agents can be beneficial as they can act additively or synergistically on different pathways, thereby enhancing the antioxidant defense. Furthermore, the utilization of immunoadjuvant therapy, specifically ...
Source: Frontiers in cellular and infection microbiology - March 6, 2024 Category: Microbiology Source Type: research