NBOMe instability in whole blood
ConclusionsBased on the potential for NBOMe instability prior to testing, it is recommended to refrigerate whole blood for NBOMe analysis up to 90 days, and to freeze samples for longer term storage. (Source: Forensic Toxicology)
Source: Forensic Toxicology - August 18, 2018 Category: Forensic Medicine Source Type: research
Crystal structures and other properties of ephedrone (methcathinone) hydrochloride, N -acetylephedrine and N -acetylephedrone
ConclusionsX-ray crystallography is especially useful for identifying the new designer drugs and their different precursor forms. (Source: Forensic Toxicology)
Source: Forensic Toxicology - August 18, 2018 Category: Forensic Medicine Source Type: research
NBOMe instability in whole blood
ConclusionsBased on the potential for NBOMe instability prior to testing, it is recommended to refrigerate whole blood for NBOMe analysis up to 90 days, and to freeze samples for longer term storage. (Source: Forensic Toxicology)
Source: Forensic Toxicology - August 18, 2018 Category: Forensic Medicine Source Type: research
A new and sensitive method for quantitative determination of helium in human blood by gas chromatography –mass spectrometry using naturally existing neon-21 as internal standard
ConclusionsThe proposed GC –SIM-MS method in combination with the naturally existing neon-21 as IS is most recommendable for quantitative assays of helium in biological samples because of its simplicity and extremely high sensitivity. (Source: Forensic Toxicology)
Source: Forensic Toxicology - August 13, 2018 Category: Forensic Medicine Source Type: research
Interpreting oral fluid drug results in prisoners: monitoring current drug intake and detection times for drugs self-administered prior to detention
ConclusionWe confirmed oral fluid as a viable matrix for monitoring drugs of abuse in prisoners. Windows of detection for benzodiazepines and amphetamines were up to 1 week, which is an important consideration for evaluating oral fluid drug testing results. Some likely new drug exposures were observed based on urine and oral fluid drug results, but there were few data to guide these interpretations. (Source: Forensic Toxicology)
Source: Forensic Toxicology - August 9, 2018 Category: Forensic Medicine Source Type: research
Fatal intoxication with 1,1-difluoroethane (DFE) due to inhalation of a spray cleaner: analysis by GC –MS
ConclusionsTo the best of our knowledge, this is the first case report of quantification of DFE in human blood and urine specimens by GC –MS. (Source: Forensic Toxicology)
Source: Forensic Toxicology - July 30, 2018 Category: Forensic Medicine Source Type: research
Effects of exposure to 5-MeO-DIPT during adolescence on brain neurotransmission and neurotoxicity in adult rats
ConclusionsThese results suggest that 5-MeO-DIPT given repeatedly during adolescence affects brain neurotransmission and shows neurotoxic potential observed in adult animals. (Source: Forensic Toxicology)
Source: Forensic Toxicology - July 19, 2018 Category: Forensic Medicine Source Type: research
Postmortem distribution of mepirapim and acetyl fentanyl in biological fluid and solid tissue specimens measured by the standard addition method
ConclusionsThe concentration of unchanged mepirapim in urine was much higher than those of other synthetic cannabinoids; the higher dosage, urinary excretion, metabolisms and/or pharmacokinetics of mepirapim may be quite different from those of other synthetic cannabinoids. (Source: Forensic Toxicology)
Source: Forensic Toxicology - July 7, 2018 Category: Forensic Medicine Source Type: research
Rapid tentative identification of synthetic cathinones in seized products taking advantage of the full capabilities of triple quadrupole analyzer
ConclusionsThis methodology will be useful for the first and rapid synthetic cathinone detection in laboratories that have low-resolution MS/MS instrumentation. (Source: Forensic Toxicology)
Source: Forensic Toxicology - July 4, 2018 Category: Forensic Medicine Source Type: research
