Inflammaging and the Age-Specific Responsiveness to Stretch-Shortening Contractions
With aging, muscle injury from rapid, continuous stretch-shortening contractions (SSC) is prolonged, and maladaptation to moderate-velocity, intermittent SSC is more common. We hypothesize that high baseline levels of inflammatory signaling and oxidative stress may underlie these outcomes, whereas careful modulation of high-intensity SSC training design resets basal conditions and permits muscle adaptation to SSC. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - September 16, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Inflammation and Oxidative Stress Limit Adaptation to Stretch-Shortening Contractions in Aging
No abstract available (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - September 16, 2017 Category: Sports Medicine Tags: Commentary to Accompany Source Type: research

Priscilla M. Clarkson Undergraduate Travel Award
No abstract available (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - September 16, 2017 Category: Sports Medicine Tags: 2017 Undergraduate Travel Award Source Type: research

Skeletal Muscle Remodeling: Interconnections Between Stem Cells and Protein Turnover
Nutrition and exercise are important components of a healthy lifestyle to improve rates of hypertrophic and nonhypertrophic skeletal muscle remodeling. We provide evidence to support the hypothesis that muscle stem cells and protein turnover are collaborative, not separate, mechanisms supporting muscle remodeling by facilitating protein, nuclear, and cellular turnover in response to the ingestion of protein dense foods and exercise. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Exercise-Induced Autophagy in Fatty Liver Disease
Hepatic steatosis prevails each year. Autophagy is integral in mitochondrial quality control and lipid homeostasis in the liver. No pharmacological strategies are currently available to reduce hepatic steatosis, but exercise has been known to improve clinical outcomes of chronic liver disease, particularly nonalcoholic fatty liver disease (NAFLD). Recent studies suggest that exercise may improve NAFLD through enhancing autophagy. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Small Sample Sizes Confound Understanding of Cardiometabolic Responses to Exercise
Considerable variability exists in the cardiometabolic disease biomarker response to exercise. We propose that a major contributor to this heterogeneity is underpowered studies due to small sample sizes. To test our hypothesis, we conducted a systematic review to identify meta-analyses/reviews of randomized controlled trials (RCT) and RCT that examined the cardiometabolic disease biomarker response to aerobic and resistance exercise. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Mobilizing Immune Cells With Exercise for Cancer Immunotherapy
Hematopoietic stem cell (HSC) transplantation and adoptive transfer immunotherapy are effective in treating blood cancers and posttransplant infections, but low-circulating cell numbers in patients and donors are oftentimes a limiting factor. We postulate that a single exercise bout will increase the yield of patient- and donor-derived HSCs and cytotoxic lymphocytes to improve this form of treatment for cancer patients. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Interval Walking Training Can Increase Physical Fitness in Middle-Aged and Older People
No long-term exercise training regimen with high adherence and effectiveness for middle-aged and older individuals is currently broadly available in the field. To address this problem, we developed an exercise training system comprising interval walking training and an information technology network that requires only minimal staff support. We hypothesized that our training system could increase physical fitness in older people. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

New Insights Into the Impact of Dehydration on Blood Flow and Metabolism During Exercise
Exercise-induced dehydration can lead to impaired perfusion to multiple regional tissues and organs. We propose that the impact of dehydration on regional blood flow and metabolism is dependent on the extent of the cardiovascular demand imposed by exercise, with the greatest physiological strain seen when approaching cardiovascular and aerobic capacities. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Physical Activity as Cause and Cure of Muscular Pain: Evidence of Underlying Mechanisms
Work-related physical activity (PA), in terms of peak loads and sustained and/or repetitive contractions, presents risk factors for the development of muscular pain and disorders. However, PA as a training tailored to the employee’s work exposure, health, and physical capacity offers prevention and rehabilitation. We suggest the concept of “Intelligent Physical Exercise Training” relying on evidence-based sports science training principles. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Perspectives for Progress Source Type: research

Exercise Is Medicine, But Does It Interfere With Medicine?
This article reviews the research that suggests exercise may influence a drug’s plasma concentration, and thus its efficacy and safety. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Perspectives for Progress Source Type: research

Interval Walking Training for Older People: No Pain and Lots of Gain
No abstract available (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Commentary to Accompany Source Type: research

Are Exercise Benefits in Nonalcoholic Fatty Liver Disease Due to Increased Autophagy?
No abstract available (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - June 17, 2017 Category: Sports Medicine Tags: Commentary to Accompany Source Type: research

Vascular Adaptations to Habitual Exercise in Older Adults: Time for the Sex Talk
This article examines the hypothesis that sex hormones modulate vascular adaptations to exercise training by influencing antioxidant defense systems, mitochondrial function, oxidative stress, and intracellular signaling. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - March 18, 2017 Category: Sports Medicine Tags: Articles Source Type: research

Individualized Exercise Interventions for Spinal Pain
Exercise is the most effective treatment for the management and prevention of spinal pain; yet on average, it delivers small to moderate treatment effects, which are rarely long lasting. This review examines the hypothesis that outcome of exercise interventions can be optimized when targeted toward the rightpatients and when tailored to address the neuromuscular impairments of each individual. (Source: Exercise and Sport Sciences Reviews)
Source: Exercise and Sport Sciences Reviews - March 18, 2017 Category: Sports Medicine Tags: Articles Source Type: research