Discussion on the Antipruritic Mechanism of Qiwei Antipruritic Based on Network Pharmacology and Molecular Docking Technology
CONCLUSION: The mechanism of Qiwei antipruritic may be related to histamine activation mechanism, calcium channel mechanism, inhibition of inflammatory signaling pathway, inhibition of neurotransmitters, and regulation of immune pathways. The traditional Chinese medicine compound Qiwei antipruritic can treat clinical pruritus through multiple targets and pathways.PMID:38021433 | PMC:PMC10657760 | DOI:10.2147/CCID.S435800 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 29, 2023 Category: Dermatology Authors: Luoxi Wang Tinghan Deng Ying Liu Hongbin Cheng Source Type: research

Maculopapular Drug Eruption Caused by Finasteride: A Case Report
Clin Cosmet Investig Dermatol. 2023 Nov 17;16:3359-3361. doi: 10.2147/CCID.S426747. eCollection 2023.ABSTRACTA 76-year-old male developed a maculopapular rash on his trunk and extremities. The rash appeared 2 months after Finasteride administration for his prostatic hyperplasia. Clinical suspicion was of drug exanthema due to Finasteride. The clinical and histologic data were compatible with pharmacologic eruption by Finasteride.PMID:38021434 | PMC:PMC10661891 | DOI:10.2147/CCID.S426747 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 29, 2023 Category: Dermatology Authors: Hongxia Jia Liwei Ran Source Type: research

Applications of Long-Pulse Alexandrite Laser in Cosmetic Dermatology: A Review
Clin Cosmet Investig Dermatol. 2023 Nov 17;16:3349-3357. doi: 10.2147/CCID.S441169. eCollection 2023.ABSTRACTThe long-pulse alexandrite laser uses Cr3+:BeAl2O4 crystals as the activation medium and has a 755nm wavelength and millisecond pulse duration. The long-pulse alexandrite laser has been utilized for hair removal, vascular lesions, pigmented lesions, and other conditions because melanin and hemoglobin in the skin, subcutaneous tissues, and skin appendages can specifically absorb this type of laser. To serve as a guide and source of inspiration for the clinical use of this type of laser, we review the present research...
Source: Clinical, Cosmetic and Investigational Dermatology - November 29, 2023 Category: Dermatology Authors: Changhan Chen Youhui Ke Source Type: research

Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research

Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research

Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research

Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research