Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research

Relationship Between Dermoscopic Capillary-Related Features of the Auricle and Earlobe and Rosacea Subtype and Disease Severity: A Cross-Sectional Analysis
CONCLUSION: The dermoscopic characteristics of capillaries in the earlobe and auricle can be used as indicators of the clinical severity of rosacea, regardless of the clinical subtype.PMID:37965100 | PMC:PMC10642572 | DOI:10.2147/CCID.S436368 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Yue Zhang Ruoxin Pan Duoduo Gu Xiaoqi Meng Tingwei Liu Yang Xu Source Type: research

Evaluation of the Effect of Oral Isotretinoin on the Level of Serum YKL40 in Acne Vulgaris Patients: A Cross-Sectional Case-Control
CONCLUSION: The conclusion of this study was that reducing the blood levels of YKL-40 and the GAGS score in patients with acne vulgaris who took oral isotretinoin for three months was a crucial strategy.PMID:37965101 | PMC:PMC10642491 | DOI:10.2147/CCID.S431856 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Mahmoud Ahmed Ali Moustafa Adam El Taieb Eisa Mohamed Hegazy Hassan M Ibrahim Alshimaa Abbas Mohamed Mohamed Amer Ahmed Abdellatif Nour Mohammed Ahmed Ali Mohamed Younis Source Type: research

Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
CONCLUSION: Our study revealed that the glycolytic enzyme HK2 was upregulated in psoriasis and that the HK2 inhibitor 3-BrPA exhibited therapeutic effects in psoriasis cell and mouse models.PMID:37965102 | PMC:PMC10642575 | DOI:10.2147/CCID.S435624 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 15, 2023 Category: Dermatology Authors: Le Zhuang Weiyuan Ma Jing Jiao Source Type: research

Characterization of Epidermal Function in Individuals with Primary Cutaneous Amyloidosis
CONCLUSION: The function of the epidermis is compromised in individuals diagnosed with PCA. However, the mechanisms underlying these changes await further investigation.PMID:37953856 | PMC:PMC10637218 | DOI:10.2147/CCID.S426209 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 13, 2023 Category: Dermatology Authors: Fujuan Huang Yuling Zhang Junyi Guo Hongju Pan Zhigang Liao Bin Yang Ping Lu Source Type: research

Effectiveness and Safety of Upadacitinib in Combination with Topical Corticosteroids in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis
CONCLUSION: These results suggest therapeutic effectiveness and tolerability of upadacitinib and support its therapeutic usefulness for adolescent AD patients.PMID:37953857 | PMC:PMC10638939 | DOI:10.2147/CCID.S439053 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 13, 2023 Category: Dermatology Authors: Teppei Hagino Risa Hamada Mai Yoshida Eita Fujimoto Hidehisa Saeki Naoko Kanda Source Type: research

Characterization of Epidermal Function in Individuals with Primary Cutaneous Amyloidosis
CONCLUSION: The function of the epidermis is compromised in individuals diagnosed with PCA. However, the mechanisms underlying these changes await further investigation.PMID:37953856 | PMC:PMC10637218 | DOI:10.2147/CCID.S426209 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 13, 2023 Category: Dermatology Authors: Fujuan Huang Yuling Zhang Junyi Guo Hongju Pan Zhigang Liao Bin Yang Ping Lu Source Type: research

Effectiveness and Safety of Upadacitinib in Combination with Topical Corticosteroids in Adolescent Patients with Moderate-to-Severe Atopic Dermatitis
CONCLUSION: These results suggest therapeutic effectiveness and tolerability of upadacitinib and support its therapeutic usefulness for adolescent AD patients.PMID:37953857 | PMC:PMC10638939 | DOI:10.2147/CCID.S439053 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 13, 2023 Category: Dermatology Authors: Teppei Hagino Risa Hamada Mai Yoshida Eita Fujimoto Hidehisa Saeki Naoko Kanda Source Type: research

Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery
CONCLUSION: In this study, we identified 10 differential metabolites as possible potential combinatorial biomarkers for the diagnosis of psoriasis. 12 metabolic pathways were significantly enriched that may be closely related to the occurrence and development of psoriasis. Three proteins, ESR1, OPRM1, and HSD11B1, were identified as possible potential therapeutic targets for psoriasis.PMID:37941849 | PMC:PMC10631377 | DOI:10.2147/CCID.S433280 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Qian Song Ying Chen JianQing Ma Wei Zhou JunYan Song ChunFu Wu Jie Liu Source Type: research

Evaluation of an Acne Severity Grading Self-Assessment System Suitable for the Thai Population - A Pilot Study
CONCLUSION: Due to the almost perfect reliability, we suggested that TGAGS is a reliable subjective self-assessment of acne severity suitable for the Thai population. The training is essential in enhancing the reliability of this instrument. Our study's findings can facilitate clinical practice and research studies.PMID:37941850 | PMC:PMC10629409 | DOI:10.2147/CCID.S427648 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Kallapan Pakornphadungsit Sarawin Harnchoowong Penpun Wattanakrai Source Type: research

Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery
CONCLUSION: In this study, we identified 10 differential metabolites as possible potential combinatorial biomarkers for the diagnosis of psoriasis. 12 metabolic pathways were significantly enriched that may be closely related to the occurrence and development of psoriasis. Three proteins, ESR1, OPRM1, and HSD11B1, were identified as possible potential therapeutic targets for psoriasis.PMID:37941849 | PMC:PMC10631377 | DOI:10.2147/CCID.S433280 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Qian Song Ying Chen JianQing Ma Wei Zhou JunYan Song ChunFu Wu Jie Liu Source Type: research

Evaluation of an Acne Severity Grading Self-Assessment System Suitable for the Thai Population - A Pilot Study
CONCLUSION: Due to the almost perfect reliability, we suggested that TGAGS is a reliable subjective self-assessment of acne severity suitable for the Thai population. The training is essential in enhancing the reliability of this instrument. Our study's findings can facilitate clinical practice and research studies.PMID:37941850 | PMC:PMC10629409 | DOI:10.2147/CCID.S427648 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Kallapan Pakornphadungsit Sarawin Harnchoowong Penpun Wattanakrai Source Type: research

Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery
CONCLUSION: In this study, we identified 10 differential metabolites as possible potential combinatorial biomarkers for the diagnosis of psoriasis. 12 metabolic pathways were significantly enriched that may be closely related to the occurrence and development of psoriasis. Three proteins, ESR1, OPRM1, and HSD11B1, were identified as possible potential therapeutic targets for psoriasis.PMID:37941849 | PMC:PMC10631377 | DOI:10.2147/CCID.S433280 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Qian Song Ying Chen JianQing Ma Wei Zhou JunYan Song ChunFu Wu Jie Liu Source Type: research