A Case of Tuberculosis Cutis Orificialis
Clin Cosmet Investig Dermatol. 2023 Sep 25;16:2659-2661. doi: 10.2147/CCID.S428884. eCollection 2023.ABSTRACTThis work reports a case of a 49-year-old male suffering from chronic tuberculosis who developed painful ulcers around the anus for approximately eight months. The colonoscopy revealed the presence of ulcers in the transverse colon, which were also found in the skin and intestine, as revealed by microscopic examination. The skin ulcer was positive for tuberculosis bacilli, leading to the final diagnosis of Tuberculosis cutis orificialis. The patient had a previous history of tuberculosis, which indicated that the in...
Source: Clinical, Cosmetic and Investigational Dermatology - October 2, 2023 Category: Dermatology Authors: XiaoYan Zhang Jifeng Liu Source Type: research

Effectiveness of Brodalumab in Patients with Moderate-to-Severe Plaque Psoriasis Located in Difficult-to-Treat Areas
CONCLUSION: Our real-life experience suggests brodalumab as a valuable option for the management of psoriasis located in difficult-to-treat areas. Moreover, our study highlights that the use of brodalumab reduces the plasmatic levels of inflammatory biomarkers (MMP-3, VEGF-A and hs-PCR), showing how the drug modulates the skin inflammatory response by reducing systemic inflammation.PMID:37780688 | PMC:PMC10541085 | DOI:10.2147/CCID.S423234 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - October 2, 2023 Category: Dermatology Authors: Sara Cacciapuoti Luca Potestio Gianluca Guerrasio Gabriella Fabbrocini Massimiliano Scalvenzi Angelo Ruggiero Giuseppina Caiazzo Matteo Megna Source Type: research

Combining Diamond-Tip Dermabrasion Treatments and Topical Skincare in Participants with Dry, Hyperpigmented, Photodamaged or Acne-Prone/Oily Facial Skin: A Clinical Usage Study
CONCLUSION: The combination of DG and DGR showed significant immediate and long-term improvements in skin appearance. These results show that the DG and DGR combination is a well-tolerated and effective intervention to enhance different aspects of facial skin quality.PMID:37780689 | PMC:PMC10540789 | DOI:10.2147/CCID.S423688 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - October 2, 2023 Category: Dermatology Authors: Lisa T Goberdhan Katie Schneider Elizabeth T Makino Rahul C Mehta Source Type: research

A Case of Tuberculosis Cutis Orificialis
Clin Cosmet Investig Dermatol. 2023 Sep 25;16:2659-2661. doi: 10.2147/CCID.S428884. eCollection 2023.ABSTRACTThis work reports a case of a 49-year-old male suffering from chronic tuberculosis who developed painful ulcers around the anus for approximately eight months. The colonoscopy revealed the presence of ulcers in the transverse colon, which were also found in the skin and intestine, as revealed by microscopic examination. The skin ulcer was positive for tuberculosis bacilli, leading to the final diagnosis of Tuberculosis cutis orificialis. The patient had a previous history of tuberculosis, which indicated that the in...
Source: Clinical, Cosmetic and Investigational Dermatology - October 2, 2023 Category: Dermatology Authors: XiaoYan Zhang Jifeng Liu Source Type: research

Effects of a Postbiotic < em > Saccharomyces < /em > and < em > Lactobacillus < /em > Ferment Complex on the Scalp Microbiome of Chinese Women with Sensitive Scalp Syndrome
In this study, the effects of topical application of postbiotic Himalaya-derived Saccharomyces and Lactobacillus ferment complex (SLFC) on the bacterial and fungal scalp microbiome at the taxonomic level and alleviation of sensitive skin syndrome were investigated.METHODS: Firstly, healthy female participants (aged 30-45) were classified into a healthy scalp group and a sensitive scalp group based on the questionnaire. Thereafter, topical application of SLFC on sensitive scalp as well as scalp microbiome was evaluated, with the difference in the distribution of microbial taxa between healthy and sensitive scalp communities...
Source: Clinical, Cosmetic and Investigational Dermatology - September 28, 2023 Category: Dermatology Authors: Yue Wang Jun Li Jianming Wu Shihong Gu Huishu Hu Rongjuan Cai Man Wang Yue Zou Source Type: research

Characteristics of Xerosis, Pruritus, and Pallor in Stage 5 Chronic Kidney Disease Patients Undergoing Hemodialysis at Dr. Hasan Sadikin General Hospital, Bandung
CONCLUSION: Xerosis, pruritus, and pallor were prevalent among patients with stage 5 CKD undergoing hemodialysis. These disorders presented with distinct demographic and clinical characteristics. Timely diagnosis and intervention have the potential to enhance the quality of life for these patients.PMID:37752968 | PMC:PMC10519221 | DOI:10.2147/CCID.S418776 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Reiva Farah Dwiyana Laila Tsaqilah Lilik Sukesi None Setiawan Erda Avriyanti Kamelia Utami Suhada Nazya Irene Zahira Source Type: research

Rehmannioside A Inhibits TRAF6/MAPK Pathway and Improves Psoriasis by Interfering with the Interaction of HaCaT Cells with IL-17A
CONCLUSION: ReA has in vitro anti-psoriatic effects and may be a new therapeutic agent for psoriasis.PMID:37752969 | PMC:PMC10519428 | DOI:10.2147/CCID.S430621 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Li-Li Yuan Chun-Yu Cao Source Type: research

Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles
CONCLUSION: This study successfully identified susceptibility loci associated with AA in the Taiwanese population. These findings not only shed light on the origins of AA within the Taiwanese context but also contribute to a comprehensive understanding of the genetic factors influencing AA susceptibility.PMID:37752970 | PMC:PMC10519225 | DOI:10.2147/CCID.S428788 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Jai-Sing Yang Ting-Yuan Liu Yu-Chia Chen Shih-Chang Tsai Yu-Jen Chiu Chi-Chou Liao Fuu-Jen Tsai Source Type: research

Characteristics of Xerosis, Pruritus, and Pallor in Stage 5 Chronic Kidney Disease Patients Undergoing Hemodialysis at Dr. Hasan Sadikin General Hospital, Bandung
CONCLUSION: Xerosis, pruritus, and pallor were prevalent among patients with stage 5 CKD undergoing hemodialysis. These disorders presented with distinct demographic and clinical characteristics. Timely diagnosis and intervention have the potential to enhance the quality of life for these patients.PMID:37752968 | PMC:PMC10519221 | DOI:10.2147/CCID.S418776 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Reiva Farah Dwiyana Laila Tsaqilah Lilik Sukesi None Setiawan Erda Avriyanti Kamelia Utami Suhada Nazya Irene Zahira Source Type: research

Rehmannioside A Inhibits TRAF6/MAPK Pathway and Improves Psoriasis by Interfering with the Interaction of HaCaT Cells with IL-17A
CONCLUSION: ReA has in vitro anti-psoriatic effects and may be a new therapeutic agent for psoriasis.PMID:37752969 | PMC:PMC10519428 | DOI:10.2147/CCID.S430621 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Li-Li Yuan Chun-Yu Cao Source Type: research

Genome-Wide Association Study of Alopecia Areata in Taiwan: The Conflict Between Individuals and Hair Follicles
CONCLUSION: This study successfully identified susceptibility loci associated with AA in the Taiwanese population. These findings not only shed light on the origins of AA within the Taiwanese context but also contribute to a comprehensive understanding of the genetic factors influencing AA susceptibility.PMID:37752970 | PMC:PMC10519225 | DOI:10.2147/CCID.S428788 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 27, 2023 Category: Dermatology Authors: Jai-Sing Yang Ting-Yuan Liu Yu-Chia Chen Shih-Chang Tsai Yu-Jen Chiu Chi-Chou Liao Fuu-Jen Tsai Source Type: research

Participant Reported Improvement in Cellulite by Vari-Pad Apparel and Objective Measurements - A "First Use" Pilot Study
CONCLUSION: The vari-padded compression garment produced a significant improvement in participant satisfaction after just 4 weeks of treatment. Objective measurements failed to show a significant difference in cellulite on the buttocks but showed a significant improvement in the thighs by analysis of both dimple volumes and reduced transcutaneous water measurements. Further study is suggested to demonstrate if longer timeframes for use of the apparel will lead to further significant improvement in the appearance of cellulite.NCT NUMBER: NCT05748678.PMID:37750084 | PMC:PMC10518180 | DOI:10.2147/CCID.S426978 (Source: Clinica...
Source: Clinical, Cosmetic and Investigational Dermatology - September 26, 2023 Category: Dermatology Authors: Melissa J Kiely Ashleigh Poulsen Simon D Muschamp Chloe Sallis Mark S Whiteley Source Type: research

Chronic Atopic Dermatitis with Eosinophilia Improved by Daesiho-Tang: A Case Report
CONCLUSION: Based on this case, DSHT is considered a potential alternative treatment for AD.PMID:37750085 | PMC:PMC10518174 | DOI:10.2147/CCID.S424225 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 26, 2023 Category: Dermatology Authors: Min-Cheol Park Ju-Hyun Lee Eun-Jin Seong Dong-Sung Lee Eun-Heui Jo Source Type: research