A New Assessment Method of Vitiligo by Combination of Dermoscopy and Reflectance Confocal Microscopy
CONCLUSION: With the higher sensitivity and specificity than dermoscopy or RCM alone, a combination of dermoscopy and RCM may be a new more accurate measure to assess the vitiligo disease activity and the treatment response.PMID:38144155 | PMC:PMC10740724 | DOI:10.2147/CCID.S432169 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Hui-Fen Wang Chun-You Wang Xiao-Fang Zhou Xiang-Fen Deng Hui Huang Juan Wang Xue-Qin Chen Zhi-Fang Zhai Source Type: research

Unbalanced Aryl Hydrocarbon Receptor Expression in Peripheral and Lesional T Cell Subsets of Atopic Dermatitis
CONCLUSION: AhR was highly expressed in subpopulations of CD4+ T cells in peripheral blood and skin lesions of AD, suggesting that AhR might contribute to the pathogenesis of AD.PMID:38144156 | PMC:PMC10749169 | DOI:10.2147/CCID.S430915 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Yu-Qing Hu Jian-Zhong Zhang Source Type: research

No-Shave Long Hair Follicular Unit Excision Using an All-Purpose Skin-Responsive Device
CONCLUSION: Our findings reveal consistent success in conducting no-shave LH-FUE using this skin-responsive device across diverse patients. Notably, success was achieved without recess-tipped punches, resulting in low GTR and SBR, along with a high GER and increased patient satisfaction. These outcomes suggest enhanced procedure speed and ease of use, contributing to a greater willingness among surgeons to adopt this technique.PMID:38144157 | PMC:PMC10746190 | DOI:10.2147/CCID.S442822 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Sanusi Umar Raveena Khanna Alejandro Gonzalez Kavish Chouhan Juan Carlos Maldonado Osman Tayfun Oguzoglu Aron Nusbaum Source Type: research

Generalized Asymptomatic Nodulo-Ulcerative Lesions Without Systemic Symptoms in a Secondary Syphilis Patient Co-Infected with HIV
Clin Cosmet Investig Dermatol. 2023 Dec 20;16:3645-3650. doi: 10.2147/CCID.S445155. eCollection 2023.ABSTRACTSyphilis is a sexually-transmitted disease with various clinical stages. Secondary syphilis manifestations may mimic other skin lesions. Patient co-infected with Human Immunodeficiency Virus (HIV), with CD4 cell counts of 200-499 cells/mm3, often manifests an atypical cutaneous lesion, which may also occur as nodular or ulcerative lesions. Generalized nodulo-ulcerative lesions without systemic symptoms in secondary syphilis patients with HIV co-infection are rarely reported. A 22-year-old man presented with generali...
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Retno Hesty Maharani Tomi Nugraha Endang Sutedja Kartika Ruchiatan Hermin Aminah Usman Pati Aji Achdiat Source Type: research

Knowledge Mapping and Research Hotspots of Generalized Pustular Psoriasis: A Bibliometric Analysis from 2003 to 2023
CONCLUSION: This bibliometric analysis delineated the landmark publications in GPP that have defined current research hotspots and development trends, notably the applications, efficacy, and safety of biological agents. Future research endeavors are warranted to explore other biological therapeutic options for both acute GPP and the long-term management of chronic GPP.PMID:38144159 | PMC:PMC10749173 | DOI:10.2147/CCID.S440741 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Lu Wei Buxin Zhang Li Wang Juntao Xu Aimin Liu Source Type: research

Interstitial Granulomatous Drug Reaction Due to Chemotherapy
Clin Cosmet Investig Dermatol. 2023 Dec 20;16:3625-3628. doi: 10.2147/CCID.S439009. eCollection 2023.ABSTRACTInterstitial granulomatous drug reaction (IGDR) is a drug-related disease with distinctive clinical and histopathological features uncommon in clinical practice. Chemotherapeutics-related IGDR has rarely been reported. Here, we describe one case of interstitial granulomatous drug reaction due to chemotherapy.PMID:38144160 | PMC:PMC10749108 | DOI:10.2147/CCID.S439009 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 25, 2023 Category: Dermatology Authors: Qiuli Zhang Jianmin Chang Source Type: research

Response of Psoriasis with Systemic Lupus Erythematosus to Secukinumab: A Case Report and Review of the Literature
We present a case of a 23-year-old female with a 10-year history of psoriasis, who had a relapse with significant joint symptoms and a PASI score of 35.6, along with several positive antibodies, including antinuclear antibodies, elevated CRP and ESR, and was diagnosed with psoriasis and SLE. She has been treated with secukinumab 300 mg subcutaneously, improving her condition. She is currently being followed up. The PubMed, SCOPUS, and ISI Web of Science databases were thoroughly searched for English studies reporting psoriasis with systemic lupus erythematosus and treated using biologics. Three case reports/series were inc...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Bowen Dai Yanping Bai HongDa Yu Qiuchen Huang Lei Wang Source Type: research

Fatty Acid Metabolism-Related lncRNAs are Potential Biomarkers for Predicting Prognoses and Immune Responses in Patients with Skin Cutaneous Melanoma
CONCLUSION: These important lncRNAs further showed a strong association with the tumor immune system, and these important lncRNAs also showed a connection between SKCM and chemotherapeutic treatment sensitivity. Our research strives to provide fresh viewpoints and innovative approaches to the treatment and administration of SKCM.PMID:38116144 | PMC:PMC10729836 | DOI:10.2147/CCID.S417805 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xing Wang Xiaojing Yang Yiming Zhang Afei Guo Suju Luo Meng Xiao Lu Xue Guohui Zhang Huiping Wang Source Type: research

Impact of COVID-19 Vaccine and COVID-19 Infection on Vitiligo Activity and Progression
Clin Cosmet Investig Dermatol. 2023 Dec 15;16:3581-3587. doi: 10.2147/CCID.S439045. eCollection 2023.ABSTRACTBACKGROUND: Coronavirus disease 2019 (COVID-19) has given rise to several new onset or exacerbated dermatologic disorders including vitiligo. However, the relationship between COVID-19 infection or its associated vaccines and vitiligo progression is unclear.AIM: We investigate the impact of COVID-19 infection and its associated vaccines on vitiligo progression.METHODS: A cross-sectional study was performed among patients who visited Department of Dermatology, Peking University People's Hospital between 2022.1 and 20...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xiaoyi Shi Yifang Sun Xiaolan Ding Source Type: research

Response of Psoriasis with Systemic Lupus Erythematosus to Secukinumab: A Case Report and Review of the Literature
We present a case of a 23-year-old female with a 10-year history of psoriasis, who had a relapse with significant joint symptoms and a PASI score of 35.6, along with several positive antibodies, including antinuclear antibodies, elevated CRP and ESR, and was diagnosed with psoriasis and SLE. She has been treated with secukinumab 300 mg subcutaneously, improving her condition. She is currently being followed up. The PubMed, SCOPUS, and ISI Web of Science databases were thoroughly searched for English studies reporting psoriasis with systemic lupus erythematosus and treated using biologics. Three case reports/series were inc...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Bowen Dai Yanping Bai HongDa Yu Qiuchen Huang Lei Wang Source Type: research

Fatty Acid Metabolism-Related lncRNAs are Potential Biomarkers for Predicting Prognoses and Immune Responses in Patients with Skin Cutaneous Melanoma
CONCLUSION: These important lncRNAs further showed a strong association with the tumor immune system, and these important lncRNAs also showed a connection between SKCM and chemotherapeutic treatment sensitivity. Our research strives to provide fresh viewpoints and innovative approaches to the treatment and administration of SKCM.PMID:38116144 | PMC:PMC10729836 | DOI:10.2147/CCID.S417805 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xing Wang Xiaojing Yang Yiming Zhang Afei Guo Suju Luo Meng Xiao Lu Xue Guohui Zhang Huiping Wang Source Type: research

Impact of COVID-19 Vaccine and COVID-19 Infection on Vitiligo Activity and Progression
Clin Cosmet Investig Dermatol. 2023 Dec 15;16:3581-3587. doi: 10.2147/CCID.S439045. eCollection 2023.ABSTRACTBACKGROUND: Coronavirus disease 2019 (COVID-19) has given rise to several new onset or exacerbated dermatologic disorders including vitiligo. However, the relationship between COVID-19 infection or its associated vaccines and vitiligo progression is unclear.AIM: We investigate the impact of COVID-19 infection and its associated vaccines on vitiligo progression.METHODS: A cross-sectional study was performed among patients who visited Department of Dermatology, Peking University People's Hospital between 2022.1 and 20...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xiaoyi Shi Yifang Sun Xiaolan Ding Source Type: research

Response of Psoriasis with Systemic Lupus Erythematosus to Secukinumab: A Case Report and Review of the Literature
We present a case of a 23-year-old female with a 10-year history of psoriasis, who had a relapse with significant joint symptoms and a PASI score of 35.6, along with several positive antibodies, including antinuclear antibodies, elevated CRP and ESR, and was diagnosed with psoriasis and SLE. She has been treated with secukinumab 300 mg subcutaneously, improving her condition. She is currently being followed up. The PubMed, SCOPUS, and ISI Web of Science databases were thoroughly searched for English studies reporting psoriasis with systemic lupus erythematosus and treated using biologics. Three case reports/series were inc...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Bowen Dai Yanping Bai HongDa Yu Qiuchen Huang Lei Wang Source Type: research

Fatty Acid Metabolism-Related lncRNAs are Potential Biomarkers for Predicting Prognoses and Immune Responses in Patients with Skin Cutaneous Melanoma
CONCLUSION: These important lncRNAs further showed a strong association with the tumor immune system, and these important lncRNAs also showed a connection between SKCM and chemotherapeutic treatment sensitivity. Our research strives to provide fresh viewpoints and innovative approaches to the treatment and administration of SKCM.PMID:38116144 | PMC:PMC10729836 | DOI:10.2147/CCID.S417805 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xing Wang Xiaojing Yang Yiming Zhang Afei Guo Suju Luo Meng Xiao Lu Xue Guohui Zhang Huiping Wang Source Type: research

Impact of COVID-19 Vaccine and COVID-19 Infection on Vitiligo Activity and Progression
Clin Cosmet Investig Dermatol. 2023 Dec 15;16:3581-3587. doi: 10.2147/CCID.S439045. eCollection 2023.ABSTRACTBACKGROUND: Coronavirus disease 2019 (COVID-19) has given rise to several new onset or exacerbated dermatologic disorders including vitiligo. However, the relationship between COVID-19 infection or its associated vaccines and vitiligo progression is unclear.AIM: We investigate the impact of COVID-19 infection and its associated vaccines on vitiligo progression.METHODS: A cross-sectional study was performed among patients who visited Department of Dermatology, Peking University People's Hospital between 2022.1 and 20...
Source: Clinical, Cosmetic and Investigational Dermatology - December 20, 2023 Category: Dermatology Authors: Xiaoyi Shi Yifang Sun Xiaolan Ding Source Type: research