Analysis of Lower-Limb Ulcers in Participants with Leprosy Sequelae Using Metabolomics and 16S Ribosomal DNA Sequencing
CONCLUSION: For participants with leprosy sequelae, skin microecology and metabolites are disturbed and species diversity and homogeneity are reduced in lower-limb ulcers, and the types of skin metabolites are dependent on the microbiota.PMID:38077917 | PMC:PMC10710263 | DOI:10.2147/CCID.S441000 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: Jian Wang Ben Wang Chao Liang Caifei Jin Huiliang Shen Source Type: research

Retrospective Analysis of 397 Dermatoses Inpatients Associated with Blood Eosinophilia
CONCLUSION: We summarize the clinical rules of dermatoses associated with blood eosinophilia, hoping to facilitate the diagnosis and treatment for patients.PMID:38077918 | PMC:PMC10700038 | DOI:10.2147/CCID.S429183 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: Ying Zhao Jing Tian Cuie Gao Lu Liu Linxin Pan Zhiqiang Song Source Type: research

Keratosis Pilaris Atrophicans Faciei: A Case Treated with 585 nm Diode Laser, a Novel Fractional Solid-State
Clin Cosmet Investig Dermatol. 2023 Dec 4;16:3497-3501. doi: 10.2147/CCID.S441779. eCollection 2023.ABSTRACTKeratosis pilaris atrophicans faciei (KPAF) is a rare, hereditary, follicular disorder categorized in the atrophicans subtypes of keratosis pilaris (KP). Nowadays it can be treated with light and laser devices. Lasers with wavelengths <600 nm, especially pulsed dye laser (PDL), are effective for treatments of KPAF. Here, we present a case with KPAF treated with 585 nm diode laser, a kind of laser system functioning with differential wavelength modified optically pumped semiconductor (D-WMOPS) technology. Our case ...
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: Melis G önülal Sinem Karaca Didem Didar Balc ı Source Type: research

Skin Inclusion: Addressing Deficits in Medical Education to Promote Diversity in Dermatological Diagnosis and Treatment
Clin Cosmet Investig Dermatol. 2023 Dec 4;16:3481-3485. doi: 10.2147/CCID.S433718. eCollection 2023.ABSTRACTDermatological conditions impact many people globally, including those with melanin-rich skin. However, insufficient medical education contributes to delayed diagnoses, misdiagnoses, and inadequate treatment for these conditions. This literature review aims to identify and address gaps in dermatological education for melanin skin. Current research reveals that medical school curricula inadequately cover these conditions, leading to low confidence among students in diagnosing and treating them. This educational defici...
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: George Ongoro Zoe Avestruz Sandra Stover Source Type: research

Advancements in the Study of Biologic Agents in Comorbidities of Psoriasis: A Literature Review
Clin Cosmet Investig Dermatol. 2023 Dec 4;16:3487-3495. doi: 10.2147/CCID.S439110. eCollection 2023.ABSTRACTThis literature review systematically searched relevant literature from the past 10 years using various medical databases, including PubMed, Medline, Cochrane, China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu. As a chronic inflammatory disease, psoriasis is associated with various cells and cytokines of the body's immune system, making them more susceptible to various systemic comorbidities than the general population. At a time when conventional regimens are ineffective and there is a lack of perso...
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: Yuhan Wang Ping Zhang Yu Lv Yu Deng Ming Yao Lin Wang Guangtao Pan Source Type: research

A Case of Erythrodermic Psoriasis Successfully Treated with Risankizumab
Clin Cosmet Investig Dermatol. 2023 Dec 5;16:3503-3507. doi: 10.2147/CCID.S447123. eCollection 2023.ABSTRACTPsoriasis is a chronic inflammatory cutaneous disease, affecting up to 3% of the worldwide population. Several clinical phenotypes can be distinguished. Among these, erythrodermic psoriasis (EP) is a rare and severe variant (less than 3% of cases), characterized by severe generalized erythema and scaling affecting at least 90% of the body surface area. EP is often a life-threatening condition, since several systemic symptoms (tachycardia, fever, fatigue, lymphadenopathy, dehydration, serum electrolyte disturbances) c...
Source: Clinical, Cosmetic and Investigational Dermatology - December 11, 2023 Category: Dermatology Authors: Matteo Megna Angelo Ruggiero Antonia Salsano Giuseppe Lauletta Antonio Portarapillo Ginevra Torta Fabrizio Martora Luca Potestio Source Type: research

Integration of Single-Cell Transcriptomics Data Reveal Differences in Cell Composition and Communication in Acne
CONCLUSION: There are significant differences in skin cell composition and cell communication patterns between acne patients and healthy people, especially reflected in gender differences. Basal cells, macrophages and endothelial cells can serve as key targets for acne treatment. The treatment methods for men and women should be more personalized.PMID:38053721 | PMC:PMC10695135 | DOI:10.2147/CCID.S436776 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 6, 2023 Category: Dermatology Authors: Chen-Xi Zhao Shi-Lei Wang Hai-Xia Li Xin Li Source Type: research

Starting Point for Protocols on the Use of Hyperdiluted Calcium Hydroxylapatite (Radiesse < sup > ® < /sup > ) for Optimizing Age-Related Biostimulation and Rejuvenation of Face, Neck, D écolletage and Hands: A Case Series Report
In conclusion, it highlights the versatility and flexibility of Radiesse® and emphasizes its efficacy and safety in skin rejuvenation and regeneration.PMID:38050476 | PMC:PMC10693750 | DOI:10.2147/CCID.S420068 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 5, 2023 Category: Dermatology Authors: Enrico Massidda Source Type: research

Applying the MD Codes ™ to Treat Emotional and Social Attributes with HA Fillers: A Retrospective Serial Case Study
CONCLUSION: Implementing the MD Codes for facial aesthetic treatment may improve facial emotional attributes as well as enhance social attributes and well-being, with natural-looking results.PMID:38050477 | PMC:PMC10693774 | DOI:10.2147/CCID.S430747 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - December 5, 2023 Category: Dermatology Authors: Mauricio de Maio Elian Elisabeth Anne Brenninkmeijer Iman Nurlin Ligia Colucci Tania Sanchez Source Type: research

A Case of Reactive Eccrine Syringofibroadenoma Associated with Dyshidrotic Eczema
Clin Cosmet Investig Dermatol. 2023 Nov 27;16:3407-3411. doi: 10.2147/CCID.S437595. eCollection 2023.ABSTRACTEccrine Syringofibroadenoma (ESFA) is an infrequent benign adnexal cutaneous lesion distinguished by hyperplastic epithelium and differentiation into eccrine ducts, displaying diverse clinical presentations. In the present case, a 48-year-old Chinese female patient exhibited a decade-long history of palmoplantar erythema, which clinically resembled Dyshidrotic Eczema. Histological examination suggested the presence of ESFA. Ultimately, considering both the clinical manifestations and histological outcomes, the patie...
Source: Clinical, Cosmetic and Investigational Dermatology - December 4, 2023 Category: Dermatology Authors: Yue Chen Xin Tian Source Type: research