Clinical, Cosmetic and Investigational Dermatology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Evaluation of an Acne Severity Grading Self-Assessment System Suitable for the Thai Population - A Pilot Study
CONCLUSION: Due to the almost perfect reliability, we suggested that TGAGS is a reliable subjective self-assessment of acne severity suitable for the Thai population. The training is essential in enhancing the reliability of this instrument. Our study's findings can facilitate clinical practice and research studies.PMID:37941850 | PMC:PMC10629409 | DOI:10.2147/CCID.S427648 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Kallapan Pakornphadungsit Sarawin Harnchoowong Penpun Wattanakrai Source Type: research

Metabolomics Reveals Molecular Signatures for Psoriasis Biomarkers and Drug Targets Discovery
CONCLUSION: In this study, we identified 10 differential metabolites as possible potential combinatorial biomarkers for the diagnosis of psoriasis. 12 metabolic pathways were significantly enriched that may be closely related to the occurrence and development of psoriasis. Three proteins, ESR1, OPRM1, and HSD11B1, were identified as possible potential therapeutic targets for psoriasis.PMID:37941849 | PMC:PMC10631377 | DOI:10.2147/CCID.S433280 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 9, 2023 Category: Dermatology Authors: Qian Song Ying Chen JianQing Ma Wei Zhou JunYan Song ChunFu Wu Jie Liu Source Type: research

Successful Treatment of Recurrent Adult-Onset Still's Disease with Tocilizumab: A Case Report and Literature Review
In this report, we present a case of successful treatment of recurrent AOSD with tocilizumab (TCZ), along with a concise review of innovative treatment strategies for AOSD based on literature retrieval.PMID:37937315 | PMC:PMC10627065 | DOI:10.2147/CCID.S431605 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 8, 2023 Category: Dermatology Authors: Xiaojing Zhong Tongtong Xu Tianhao Li Nana Luo Nan Luo Pingsheng Hao Source Type: research

Disseminated Herpes Zoster with Decreased CD4 Counts in a HIV-Infected Patient
Clin Cosmet Investig Dermatol. 2023 Nov 2;16:3165-3170. doi: 10.2147/CCID.S429308. eCollection 2023.ABSTRACTHerpes zoster is typically a blister rash involving a single skin group, caused by the reactivation of primary varicella zoster virus infection. Disseminated herpes zoster refers to the presence of more than 20 small blisters outside the primary or adjacent skin, which is rare and usually occurs in individuals with weakened immune function. This case described a patient diagnosed with disseminated herpes zoster, with a decrease in CD4 count (379 cells/mm3) and certain skin lesions. He was subsequently screened positi...
Source: Clinical, Cosmetic and Investigational Dermatology - November 8, 2023 Category: Dermatology Authors: Linxi Zeng Sen Feng Lulu Yao Jiaqing Zhao Guoqiang Zhang Source Type: research

Variation of Ferroptosis-Related Markers in HaCaT Cell Photoaging Models Induced by UVB
CONCLUSION: According to the findings, ferroptosis may be linked to UVB-induced skin photoaging, which could be attenuated by inhibition of ferroptosis.PMID:37937317 | PMC:PMC10626151 | DOI:10.2147/CCID.S433071 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 8, 2023 Category: Dermatology Authors: Peng-Cheng Zhang Yi Hong Shi-Qin Zong Long Chen Chong Zhang Dai-Zhi Tian Dan Ke Li-Ming Tian Source Type: research

JAK Inhibitors in Psoriatic Disease
Clin Cosmet Investig Dermatol. 2023 Oct 31;16:3129-3145. doi: 10.2147/CCID.S433367. eCollection 2023.ABSTRACTPsoriasis is now considered to be the cutaneous phenotype of a systemic inflammatory condition, recognized under the term Psoriatic Disease (PsD). PsD has several extracutaneous manifestations, such as inflammatory articular and entheseal involvement, leading to psoriatic arthritis (PsA), and the less frequent intestinal and ocular manifestations with colitis/inflammatory bowel disease and uveitis, respectively. There have also been several reports of an increased frequency of comorbidities such as hypertension, dia...
Source: Clinical, Cosmetic and Investigational Dermatology - November 6, 2023 Category: Dermatology Authors: Matteo Megna Luca Potestio Angelo Ruggiero Sara Cacciapuoti Francesco Maione Marco Tasso Francesco Caso Luisa Costa Source Type: research

The Future Landscape of Endothelial Cells Research in Psoriasis: Bibliometric Analysis and Literature Review
CONCLUSION: This bibliometric analysis sheds light on the growing acknowledgement of the involvement of endothelial cells in psoriasis, with the United States taking the lead. It also emphasizes the necessity for additional research to unravel the underlying mechanisms connecting psoriasis, endothelial dysfunction, and cardiovascular comorbidities. Ultimately, this research will contribute to the development of enhanced management strategies for psoriasis patients.PMID:37927385 | PMC:PMC10624204 | DOI:10.2147/CCID.S435085 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 6, 2023 Category: Dermatology Authors: Si-Yu Long Lin Shang Huijuan Shi Siqi Zhao Jiali Cao Yanling He Source Type: research

Causal Relationship Between Blood Triglyceride Levels and Age Spots: A Mendelian Randomization Analysis
CONCLUSION: The MR analysis proved that TLIB has a protective effect against AS and that triglycerides have potential preventive and therapeutic effects against AS. However, the specific dose-effect relationship requires further study.PMID:37927386 | PMC:PMC10625373 | DOI:10.2147/CCID.S431276 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - November 6, 2023 Category: Dermatology Authors: Hongtao Liu Shaopeng Ming Source Type: research