A Chronic Multiple Site of Scrofuloderma: Is It Reactivation or Treatment Failure of Tuberculosis?
We report a case of 32-year-old patient who presented with painless erythematous plaque gradually ulcerated for 9 years. He had a history of pulmonary tuberculosis 12 years ago and was cured by the treatment of 2HRZE/4HR. The laboratory examination of t-spot and PPD skin test was positive. Histopathology examinations of left cervical lymph node as well as skin revealed granulomatous inflammation with caseous necrosis. A diagnosis of scrofuloderma was made. Negative sputum culture and chest CT scan results excluded pulmonary tuberculosis. The patient was treated with a standard antituberculosis therapy and recovered well af...
Source: Clinical, Cosmetic and Investigational Dermatology - September 13, 2023 Category: Dermatology Authors: Xianhong Yang Yunlin Ren Huachu Liu Yan Ten Yang Ding Shasha Fan Xiaohua Tao Wei Lu Source Type: research

Application of Adjustable Skin Stretchers in Repairing Wound-Related Defects
CONCLUSION: Adjustable skin stretchers can accurately control the tension on wound margins, breaking the limitation of previous stretchers to provide objective quantitative indicators for clinical application. These stretchers are characterized by high use-value and are worth promoting.PMID:37694193 | PMC:PMC10492556 | DOI:10.2147/CCID.S411870 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Zhimin Shen Shiping Chen Yiqiang Duan Juan Yu Dayang Pan Jiaxin Dong Shanglong Wang Qizhe Li Yinlong Xiao Xun Yuan Source Type: research

Onychopathy Following Durvalumab Treatment for Extensive-Stage Small-Cell Lung Cancer: A Case Report
Clin Cosmet Investig Dermatol. 2023 Sep 5;16:2429-2432. doi: 10.2147/CCID.S415119. eCollection 2023.ABSTRACTPatients treated with immune checkpoint inhibitors (ICIS) are prone to immune related adverse events (irAEs), making it important to pay attention to these adverse events. Herein, we report a case of onychopathy after treatment of extensive small cell lung cancer (ES-SCLC) with durvalumab; this is the first report of onychopathy caused by durvalumab in a patient with lung cancer. The change in the patient's nails mainly manifested in the form of pigmentation and the thickening of the nails. Antifungal ointment was in...
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Cuifen Zhang Ke Wang Hong Zhang Jingjing Liu Chuangjie Zheng Jiahao Tao Lizhu Lin Linzhu Zhai Source Type: research

Analysis of Adverse Reactions of Cosmetics in Chinese Han Population in Recent Five Years
CONCLUSION: This study complements the data reported on cosmetic adverse reactions in the Chinese Han population and suggests that in future clinical diagnosis and data collection, emphasis should be placed on patch testing, combining the patch test with cosmetic protoplast with the European standard allergen test to improve the detection rate.PMID:37694195 | PMC:PMC10492557 | DOI:10.2147/CCID.S418591 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Canbin Dong Fang Liu Zuda Liao Lanmei Lin Runnan Wang Juan Du Wen Huang Source Type: research

Application of Adjustable Skin Stretchers in Repairing Wound-Related Defects
CONCLUSION: Adjustable skin stretchers can accurately control the tension on wound margins, breaking the limitation of previous stretchers to provide objective quantitative indicators for clinical application. These stretchers are characterized by high use-value and are worth promoting.PMID:37694193 | PMC:PMC10492556 | DOI:10.2147/CCID.S411870 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Zhimin Shen Shiping Chen Yiqiang Duan Juan Yu Dayang Pan Jiaxin Dong Shanglong Wang Qizhe Li Yinlong Xiao Xun Yuan Source Type: research

Onychopathy Following Durvalumab Treatment for Extensive-Stage Small-Cell Lung Cancer: A Case Report
Clin Cosmet Investig Dermatol. 2023 Sep 5;16:2429-2432. doi: 10.2147/CCID.S415119. eCollection 2023.ABSTRACTPatients treated with immune checkpoint inhibitors (ICIS) are prone to immune related adverse events (irAEs), making it important to pay attention to these adverse events. Herein, we report a case of onychopathy after treatment of extensive small cell lung cancer (ES-SCLC) with durvalumab; this is the first report of onychopathy caused by durvalumab in a patient with lung cancer. The change in the patient's nails mainly manifested in the form of pigmentation and the thickening of the nails. Antifungal ointment was in...
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Cuifen Zhang Ke Wang Hong Zhang Jingjing Liu Chuangjie Zheng Jiahao Tao Lizhu Lin Linzhu Zhai Source Type: research

Analysis of Adverse Reactions of Cosmetics in Chinese Han Population in Recent Five Years
CONCLUSION: This study complements the data reported on cosmetic adverse reactions in the Chinese Han population and suggests that in future clinical diagnosis and data collection, emphasis should be placed on patch testing, combining the patch test with cosmetic protoplast with the European standard allergen test to improve the detection rate.PMID:37694195 | PMC:PMC10492557 | DOI:10.2147/CCID.S418591 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 11, 2023 Category: Dermatology Authors: Canbin Dong Fang Liu Zuda Liao Lanmei Lin Runnan Wang Juan Du Wen Huang Source Type: research

Lipid Metabolism Reprogramming of Immune Cells in Acne: An Update
Clin Cosmet Investig Dermatol. 2023 Sep 1;16:2391-2398. doi: 10.2147/CCID.S424478. eCollection 2023.ABSTRACTAcne vulgaris is one of the most widespread skin conditions and the main reason for visiting a dermatologist. Inflammatory response and abnormal infiltrations of immune cells are the main pathogenesis of acne. The increased lipid is the prerequisite for the acne, and the perturbation of lipid composition and content is consistent with the severity of acne. Furthermore, the increased lipid production not only contributes to the occurrence and development of acne, but also sensitizes the function of immune cells. The l...
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Shuhui Wu Xi Zhang Yun Wang Huie Zheng Mingfang Zhu Source Type: research

Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures
CONCLUSION: Surgical excision with second-intention healing aided by guarded high-tension sutures effectively treated small and extensive FD lesions with no recurrence at long-term follow-up. To our knowledge, this is the first report of successful surgical treatment of FD.PMID:37675182 | PMC:PMC10478779 | DOI:10.2147/CCID.S422077 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Sanusi Umar Ade Waterman Donna Ton Paul Shitabata Source Type: research

Curcumin Alleviates Epidermal Psoriasis-Like Dermatitis and IL-6/STAT3 Pathway of Mice
CONCLUSION: CUR can effectively ameliorate the featured lesions of psoriasis mice, which may be closely associated with the involvement of IL-6/STAT3 signaling.PMID:37675183 | PMC:PMC10478781 | DOI:10.2147/CCID.S423922 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Zhenguo Cai Yibin Zeng Zhuohang Liu Ruizheng Zhu Wuqing Wang Source Type: research

Lipid Metabolism Reprogramming of Immune Cells in Acne: An Update
Clin Cosmet Investig Dermatol. 2023 Sep 1;16:2391-2398. doi: 10.2147/CCID.S424478. eCollection 2023.ABSTRACTAcne vulgaris is one of the most widespread skin conditions and the main reason for visiting a dermatologist. Inflammatory response and abnormal infiltrations of immune cells are the main pathogenesis of acne. The increased lipid is the prerequisite for the acne, and the perturbation of lipid composition and content is consistent with the severity of acne. Furthermore, the increased lipid production not only contributes to the occurrence and development of acne, but also sensitizes the function of immune cells. The l...
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Shuhui Wu Xi Zhang Yun Wang Huie Zheng Mingfang Zhu Source Type: research

Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures
CONCLUSION: Surgical excision with second-intention healing aided by guarded high-tension sutures effectively treated small and extensive FD lesions with no recurrence at long-term follow-up. To our knowledge, this is the first report of successful surgical treatment of FD.PMID:37675182 | PMC:PMC10478779 | DOI:10.2147/CCID.S422077 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Sanusi Umar Ade Waterman Donna Ton Paul Shitabata Source Type: research

Curcumin Alleviates Epidermal Psoriasis-Like Dermatitis and IL-6/STAT3 Pathway of Mice
CONCLUSION: CUR can effectively ameliorate the featured lesions of psoriasis mice, which may be closely associated with the involvement of IL-6/STAT3 signaling.PMID:37675183 | PMC:PMC10478781 | DOI:10.2147/CCID.S423922 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Zhenguo Cai Yibin Zeng Zhuohang Liu Ruizheng Zhu Wuqing Wang Source Type: research

Lipid Metabolism Reprogramming of Immune Cells in Acne: An Update
Clin Cosmet Investig Dermatol. 2023 Sep 1;16:2391-2398. doi: 10.2147/CCID.S424478. eCollection 2023.ABSTRACTAcne vulgaris is one of the most widespread skin conditions and the main reason for visiting a dermatologist. Inflammatory response and abnormal infiltrations of immune cells are the main pathogenesis of acne. The increased lipid is the prerequisite for the acne, and the perturbation of lipid composition and content is consistent with the severity of acne. Furthermore, the increased lipid production not only contributes to the occurrence and development of acne, but also sensitizes the function of immune cells. The l...
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Shuhui Wu Xi Zhang Yun Wang Huie Zheng Mingfang Zhu Source Type: research

Refractory Folliculitis Decalvans Treatment Success with a Novel Surgical Excision Approach Using Guarded High-Tension Sutures
CONCLUSION: Surgical excision with second-intention healing aided by guarded high-tension sutures effectively treated small and extensive FD lesions with no recurrence at long-term follow-up. To our knowledge, this is the first report of successful surgical treatment of FD.PMID:37675182 | PMC:PMC10478779 | DOI:10.2147/CCID.S422077 (Source: Clinical, Cosmetic and Investigational Dermatology)
Source: Clinical, Cosmetic and Investigational Dermatology - September 7, 2023 Category: Dermatology Authors: Sanusi Umar Ade Waterman Donna Ton Paul Shitabata Source Type: research