Should FDG PET/CT or PET/MR replace WBC scan in infectious and inflammatory disease?
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - July 10, 2021 Category: Radiology Source Type: research
Breaking the paradigm to renew the Nuclear Medicine Department …
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - July 10, 2021 Category: Radiology Source Type: research
Topographical patterns of whole-brain structural alterations in association with genetic risk, cerebrospinal fluid, positron emission tomography biomarkers of Alzheimer ’s disease, and neuropsychological measures
ConclusionsStrong evidence suggests that atrophy of the AD vulnerable regions is associated with CSF and PET biomarkers and cognitive measures. These relationships may be potentially helpful in characterizing the preclinical and clinical stages of MCI and AD and predicting AD progression. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - July 1, 2021 Category: Radiology Source Type: research
Anemia and PET imaging
ConclusionPET imaging is useful for assessing various types of anemia. It is also important to be aware of anemia-related PET findings to avoid mistaking them for malignancy or metastases. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 30, 2021 Category: Radiology Source Type: research
Health technology assessment for PSMA-PET: striving towards a cost-effective management of prostate cancer
ConclusionPSMA-PET has the potential to save time and reduce costs from a patient and health-care perspective, by providing a more accurate disease staging and leading to more effective, personalized, imaging-guided approach. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 26, 2021 Category: Radiology Source Type: research
Peptide receptor radionuclide therapy for GEP-NET: consolidated knowledge and innovative applications
ConclusionPRRT is now recognized as an effective treatment strategy for well-differentiated SSTR-positive NETs with a very high disease control and overall limited toxicity. Further optimization of PRRT employment is warranted to further increase efficacy and reduce toxicity. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 24, 2021 Category: Radiology Source Type: research
Amyloid PET in the diagnostic workup of neurodegenerative disease
AbstractSeveral radiotracers have been employed to bind amyloid plaques in the brain for the differential diagnosis of neurodegenerative disease, open the possibility to measure in vivo pathogenic processes implicated in Alzheimer disease (AD) and have the potential to detect disease processes at the earliest stages with a potential role in clinical trials ’ longitudinal assessment. Visual reading is clinically adequate in clearly positive or negative cases but the adoption of validated and standardized quantification methods of amyloid-PET to diagnose AD in research and clinical settings has become essential. The presen...
Source: Clinical and Translational Imaging - June 23, 2021 Category: Radiology Source Type: research
Toward radiotheranostics in cancer stem cells: a promising initial step for tumour eradication
ConclusionThere is an essential need to consider the combination of conventional cancer treatment methods and specific CSCs therapies to complete eradication of heterogeneous tumour mass. Nuclear molecular imaging with an incorporated theranostic approach is a proposed platform that combines diagnostics and therapy as well as facilitates individual patient treatment. Currently, there are only early steps, but these steps display promising results of CSC-targeting using the theranostics approach. Further high-throughput research should be directed towards the greater development of the theranostics approach in CSCs to impro...
Source: Clinical and Translational Imaging - June 22, 2021 Category: Radiology Source Type: research
Ultrasound and shear-wave elastography patterns of COVID-19 mRNA vaccine-related axillary, supra and subclavicular lymphadenopathy
AbstractIn this pictorial essay, we illustrate the ultrasound appearance of COVID-19 Pfizer-BioNTech vaccine-related lymph node abnormalities, which can occur at different stations ipsilateral to the site of vaccination, after either first or second vaccine dose and can represent a diagnostic dilemma when encountered in patients with underlying conditions. Typically, they appear as enlarged hypoechoic nodes with loss of fat hilum, increased hilar and cortical vascularization at color-Doppler, but low to intermediate cortical consistence at shear-wave elastography. Asymmetric or diffuse cortical thickening is also frequentl...
Source: Clinical and Translational Imaging - June 18, 2021 Category: Radiology Source Type: research
Humbug in a nuclear medicine department?
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 7, 2021 Category: Radiology Source Type: research
A multicenter survey of current practices of 99mTc-methoxy-isobutyl-isonitrile (MIBI) imaging for the diagnosis of thyroid nodules: more standardization is essential
ConclusionsOur survey supports the urgent need of standardized interpretation criteria of thyroid MIBI imaging in order to improve its diagnostic performance and make results comparable in clinical practice. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 2, 2021 Category: Radiology Source Type: research
An easy and practical guide for imaging infection/inflammation by [18F]FDG PET/CT
ConclusionsDespite [18F]FDG is currently used in several inflammatory and infective diseases, standardized interpretation criteria are still needed in most cases. It is, therefore, foreseen the execution of multicentre clinical studies that, by adopting the same acquisition and interpretation criteria, may contribute to the standardization of this imaging modality. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 1, 2021 Category: Radiology Source Type: research
Impact of 18F-FDG PET on the management of recurrent breast cancer: a meta-analysis
Conclusions18F-FDG PET has a major impact on the management of patients with breast cancer after curative surgery. These findings suggest that18F-FDG PET should be performed in patients with breast cancer in cases involving equivocal or suspicious recurrence/metastasis on conventional imaging or in cases involving elevated tumor markers during follow-up. However, this study does not support the routine use of18F-FDG PET for surveillance in breast cancer. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 1, 2021 Category: Radiology Source Type: research
Assessment of therapy response to Regorafenib by 18F-DOPA-PET/CT in patients with recurrent high-grade gliomas: a case series
DiscussionThese preliminary findings suggest that18F-DOPA PET/CT allows an early and reliable assessment of metabolic response to the REG treatment. A major advantage of PET seems to be obtained in patients in whom MR is unable to differentiate non-response vs tumor pseudo-progression. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - June 1, 2021 Category: Radiology Source Type: research
Spotlight on: guideline on current good radiopharmacy practice (cGRPP) for the small-scale preparation of radiopharmaceuticals published in EJNMMI Radiopharmacy and Chemistry (2021)6:8
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - May 28, 2021 Category: Radiology Source Type: research
