Clinical applications of long axial field-of-view PET/CT scanners in oncology
ConclusionsLAFOV PET/CT showed superior diagnostic performance than traditional SAFOV devices, allowing reduced activity/time and dynamic protocols. The applications of this novel technology in some clinical settings, mainly the pediatric population, are promising but should be a topic of future investigations. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 22, 2023 Category: Radiology Source Type: research

Actionable imaging findings in the daily PET/CT scenario
ConclusionA systematic categorization of the actionable imaging findings according to their prognostic severity may help the reporting physician to choose how and when to communicate with the referring clinician or to identify cases requiring a prompt clinical evaluation. Effective communication is a critical component of diagnostic imaging: timely receipt of the information is more important than the method of delivery. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 18, 2023 Category: Radiology Source Type: research

Expert review for clinical and translational imaging actionable imaging findings in the daily PET/CT scenario
ConclusionA systematic categorization of the actionable imaging findings according to their prognostic severity may help the reporting physician to choose how and when to communicate with the referring clinician or to identify cases requiring a prompt clinical evaluation. Effective communication is a critical component of diagnostic imaging: timely receipt of the information is more important than the method of delivery. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 18, 2023 Category: Radiology Source Type: research

Digital PET for recurrent prostate cancer: how the technology help
AbstractDigital PET is characterized by high sensitivity, spatial and temporal resolution, with growing applications of this technology both in clinical practice and in research settings. Further studies are needed, but the role of digital PET imaging in recurrent prostate cancer is promising, especially in terms of increasing detection rate of the disease. The aim of this mini-review is to provide a general overview of digital PET imaging in recurrent prostate cancer field, by describing the published results and by discussing the open question related to known advantages and eventual disadvantages of using this novel tec...
Source: Clinical and Translational Imaging - February 17, 2023 Category: Radiology Source Type: research

The emerging role of positron emission tomography (PET) in the management of photon radiotherapy-induced vasculitis in head and neck cancer patients
ConclusionFDG-PET/CT and NaF-PET/CT hold significant potential as preliminary diagnostic tools in monitoring early inflammation and atherosclerotic plaque development, warranting further research and attention. Applying these techniques in this context may foster proactive and consistent assessments of RT-induced vasculitis in HNC patients, mitigating potential cardiovascular risks through better-informed treatment decisions. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 17, 2023 Category: Radiology Source Type: research

From bottleneck to enabler: a new approach to regulating data-driven medical research
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 15, 2023 Category: Radiology Source Type: research

FDG-PET metrics in advanced non-small cell lung cancer (NSCLC): a review and meta-analysis
ConclusionBaseline PET metrics are powerful prognostic factors for advanced NSCLC patients who are treated with chemotherapy or targeted therapy. Further examination of the prognostic value of PET metrics for patients who receive first-line immunotherapy is warranted. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 9, 2023 Category: Radiology Source Type: research

PSMA PET/CT imaging for biochemical recurrence of prostate cancer after radiotherapy: is it necessary to review the Phoenix criteria?
ConclusionsThe development of PSMA PET/CT questions the need for a review of the Phoenix criteria. Solid studies are needed to evaluate new PSA thresholds to redefine these criteria considering the clinical benefit to the patient of changing the therapeutic approach at different stages of the disease. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 29, 2023 Category: Radiology Source Type: research

A systematic review for using deep learning in bone scan classification
ConclusionDeep-learning-based models have shown strong potential for incorporation into the clinical scenario of diagnosis assistance. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 21, 2023 Category: Radiology Source Type: research

The sodium iodide symporter (NIS) as theranostic gene: potential role in pre-clinical therapy of extra-thyroidal malignancies
ConclusionNIS-mediated expression in combination with  131I can be considered a promising  approach in the preclinical treatment of extra-thyroidal malignancies and metastases. Malignant cells expressing NIS are thought to accumulate radionuclides intracellularly, which contributes to the remarkable therapeutic effects observed. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 16, 2023 Category: Radiology Source Type: research

Evidence-based medicine: reviews and meta-analysis
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 8, 2023 Category: Radiology Source Type: research

18F-FDG PET/CT in peritoneal tumors: a pictorial review
AbstractPathologic involvement of the peritoneum can result from a wide range of conditions, including both non-neoplastic and neoplastic diseases. In the latter case, the peritoneum can be affected by primary tumors and, more commonly, secondary pathologic implants. In this heterogeneous spectrum of diseases, morphological imaging, especially computed tomography (CT), is the method of choice in detecting peritoneal implants as well as treatment response evaluation.18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is a reference technique in the oncological field and to date can be co...
Source: Clinical and Translational Imaging - January 7, 2023 Category: Radiology Source Type: research

Thyroid incidentalomas in PSMA PET/CT: a systematic review and meta-analysis
ConclusionTI is rarely detected on PSMA PET/CT, and the risk of malignancy can reach considerable values in lesions with a focal pattern. Therefore, follow-up and appropriate clinical investigation of lesions with focal PSMA uptake in the thyroid are important. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - December 27, 2022 Category: Radiology Source Type: research

The diagnostic performance of 2-[18F]FDG PET/CT for the recurrent colorectal cancer in patients with elevated CEA versus normal CEA: a systematic review and meta-analysis
ConclusionsBased on the pooled results, we tentatively conclude that 2-[18F]FDG PET/CT has a good performance in recurrent CRC patients and the diagnostic performance of 2-[18F]FDG PET/CT will significantly improve if there is a prior CEA elevation. Further prospective studies with a larger sample size would draw more accurate conclusions. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - December 16, 2022 Category: Radiology Source Type: research

Myocardial perfusion imaging in the era of COVID-19: a systematic review
ConclusionWe observed through the article review that CT scans performed in combination with MPI are crucial and should be interpreted within the context of COVID, especially during outbreaks. Moreover, we discovered that in the initial months of the pandemic, the number of SPECT MPIs performed globally decreased, with the fall being more significant in some countries, primarily in low- to middle-income regions. Lastly, we found that individuals with a history of COVID-19 may be more prone to having MPIs that demonstrate abnormalities, such as ischemia.Graphical abstract (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - December 15, 2022 Category: Radiology Source Type: research