Prevalence of thyroid dysfunction in patients with COVID-19: a systematic review
ConclusionLiterature data show that thyroid dysfunction is present in a significant percentage of patients with COVID-19. Assessment of thyroid function may be considered in symptomatic COVID-19 patients to have a baseline before introducing thyroid-interfering drugs and those requiring high-intensity care. Further, well-designed studies are needed to better elucidate the impact of COVID-19 on thyroid function and inform thyroid function testing and thyroid dysfunction management in COVID-19 patients. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 11, 2021 Category: Radiology Source Type: research
Systematic review of lung shunt fraction quantification comparing SPECT/CT and planar scintigraphy for yttrium 90 radioembolization planning
ConclusionThe current clinical assessment of LSF is substantially overestimated by 2D planar scintigraphy when compared to 3D SPECT/CT. However, unclearness of blinding between the index test and reference standard was an area of quality concern. Hence, further randomized or prospective studies are needed to strengthen the role of SPECT/CT in lung shunt fraction estimation. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 10, 2021 Category: Radiology Source Type: research
Lean approach to improving performance and efficiency in a nuclear medicine department
ConclusionLean tools have the potential to reduce error and costs and improve quality. Because Radiology and Nuclear Medicine departments are similar concerning patient processes, they have plenty of potentials to benefit from systematic Lean adoption. We believe these principles can be applied to other health care delivery areas. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 9, 2021 Category: Radiology Source Type: research
SeHCAT test for bile acid malabsorption: may “the old” become “the gold one” in the diagnostic burden of chronic diarrhea?
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 6, 2021 Category: Radiology Source Type: research
Assessment of therapy response to Regorafenib by 18 F-DOPA-PET/CT in patients with recurrent high-grade gliomas: a case series
DiscussionThese preliminary findings suggest that18F-DOPA PET/CT allows an early and reliable assessment of metabolic response to the REG treatment. A major advantage of PET seems to be obtained in patients in whom MR is unable to differentiate non-response vs tumor pseudo-progression. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 6, 2021 Category: Radiology Source Type: research
Pictorial essay: incidental findings on 18 F-Fluciclovine PET/CT scan
DiscussionClinical cases selected in this pictorial essay have demonstrated that Fluciclovine is not an exclusive and specific radiotracer for prostate cancer and, therefore, can induce misdiagnosis. In fact, incidental benign and malignant uptake might occur and should be further evaluated with clinical correlation or other imaging. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 7, 2021 Category: Radiology Source Type: research
Comprehensive review on design perspective of PET ligands based on β-amyloids, tau and neuroinflammation for diagnostic intervention of Alzheimer’s disease
ConclusionOur comprehensive review will provide comparison and help in the design perspective of the futuristic PET tracers for Alzheimer's disease by improving their affinity towards biomarkers with higher selectivity A β/tau for delineation of AD at an early stage.Graphic abstract (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - February 3, 2021 Category: Radiology Source Type: research
Funding of nuclear medicine research and association with citation impact
ConclusionsMore than half of research in major nuclear medicine journals declared funding. The far majority were supported federally, followed by non-profit foundations, intramural institutional foundations, and private industry. Funding was associated with higher citation impact. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 28, 2021 Category: Radiology Source Type: research
Deep learning in Nuclear Medicine —focus on CNN-based approaches for PET/CT and PET/MR: where do we stand?
DiscussionOverall, CNN applications for PET/CT and PET/MR are exponentially growing, demonstrating encouraging results for both technical and clinical purposes. Novel research strategies emerged to face the challenges of DL algorithms development. Education and confidence with DL-based tools are needed for proper technology implementation. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 28, 2021 Category: Radiology Source Type: research
New kid on the block in theranostics: Glypican-3
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 23, 2021 Category: Radiology Source Type: research
Cervical alterations in Hirayama disease: an MRI and FDG-PET combined approach
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 22, 2021 Category: Radiology Source Type: research
Impact of PSMA PET on management of biochemical recurrent prostate cancer: a systematic review and meta-analysis of prospective studies
ConclusionPSMA PET had an impact on the clinical management of BRPCa in 61% patients. A higher proportion ongoing ADT was associated with a higher proportion of management change. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 19, 2021 Category: Radiology Source Type: research
Change of management by using hybrid imaging with radiolabelled choline in biochemical recurrent prostate cancer: a systematic review and a meta-analysis
ConclusionsOur meta-analysis demonstrated that hybrid imaging with radiolabelled choline may change the management in about half of BRPCa patients. However, as for other PET radiopharmaceuticals, large-scale prospective multicentric studies are needed to investigate whether BRPCa patients can benefit from PET-related treatment changes. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 17, 2021 Category: Radiology Source Type: research
Molecular imaging of pancreatic neoplasms
ConclusionFDG PET/CT plays a key role in PDAC in staging, restaging as well as disease monitoring during follow-up. Functional imaging with68Ga-labeled SSA is the gold standard in imaging of well-differentiated pNETs. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 13, 2021 Category: Radiology Source Type: research
Head-to-head comparison between 18 F-FDG PET/low-dose CT and 18 F-FDG PET/contrast-enhanced CT in relapsing ovarian carcinoma: a systematic review and meta-analysis
In this study, a systematic review of the literature with a meta-analysis was carried out to compare18F-FDG PET/ldCT18F-FDG PET/ceCT in relapsing OC.Materials and methodsWe performed a systematic review of the literature through the most relevant databases and web sources. Original articles published before September 2020 and concerning a direct comparison of18F-FDG PET/ceCT and18F-FDG PET/ldCT in detecting an OC recurrence were considered. A proportion meta-analysis was then performed using a random-effects model.ResultsOut of 111 identified papers, a total of four (296 patients) were selected, all of them representing re...
Source: Clinical and Translational Imaging - January 5, 2021 Category: Radiology Source Type: research
