Dynamic whole-body FDG-PET imaging for oncology studies
ConclusionDynamic whole-body FDG-PET imaging permits assessment of serial FDG uptake change which is particularly useful for differentiation of pathological uptake from physiological uptake with high diagnostic accuracy. This imaging can be applied for minimizing motion artifacts. Wide clinical applications of such serial, dynamic whole-body PET imaging is expected in oncological studies in the near future. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - January 20, 2022 Category: Radiology Source Type: research
Clinical application of radioiodinated antibodies: where are we?
AbstractEradication of cancer still remains an upsetting issue despite our increased understanding of the molecular basis of carcinogenesis. Factors such as the molecular heterogeneity of some tumours and initial diagnosis at advanced stages hamper effective disease treatment. Given the ineffectiveness of current treatments, the development of newer therapeutic modalities to address clinical unmet needs is still mandatory. Radioimmunotherapy (RIT) that combines the use of specific antibodies against tumour-associated antigens with the cytotoxic properties of therapeutic radionuclides is amongst those approaches. The potent...
Source: Clinical and Translational Imaging - January 11, 2022 Category: Radiology Source Type: research
Thoracic imaging radiomics for staging lung cancer: a systematic review and radiomic quality assessment
ConclusionThe current level of evidence of radiomic analysis methods for staging lung cancer is inconclusive and possesses heterogeneity in study design. Prospective external validation of these algorithms and direct comparisons using cut-off thresholds is required to determine their true predictive capability prior to implementation in clinical practice.PROSPERO ID: CRD42020162952. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - November 25, 2021 Category: Radiology Source Type: research
Interest of researchers in ultrasound systems for risk stratification of thyroid nodules (TIRADS): a systematic review
ConclusionsThe number of scientific articles focused on TIRADSs/RSSs is high and it has been importantly increased over the time. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - November 13, 2021 Category: Radiology Source Type: research
Breaking the “pear dime?”
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - November 13, 2021 Category: Radiology Source Type: research
Diagnostic efficacy of bone scintigraphy in transthyretin cardiac amyloidosis: an updated systematic review and Bayesian bivariate meta-analysis
ConclusionsBone scintigraphy has an excellent diagnostic performance in ATTR-CA. An accurate diagnosis of ATTR-CA can be made based on the semi-quantitative visual score, quantitative ratios of planar imaging, and cardiac bone-tracer uptake values of SPECT images. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - November 12, 2021 Category: Radiology Source Type: research
PET/MR for evaluation of musculoskeletal malignancies
ConclusionsDespite limited evidence and the lack of widespread application, PET/MR is a promising imaging technique for evaluating musculoskeletal malignancies. This is owing primarily to the strength of its constituent modalities. PET permits for acquisition of metabolic information using a variety of emerging novel radiopharmaceuticals. MR allows for assessment of bone marrow and for identification and characterization of soft-tissue lesions. Selection of appropriate radiopharmaceutical and MR protocol parameters is key for optimal evaluation. Although PET/MR has shown promise in evaluation of musculoskeletal involvement...
Source: Clinical and Translational Imaging - November 5, 2021 Category: Radiology Source Type: research
The utilization of positron emission tomography in the evaluation of renal health and disease
ConclusionPET imaging provides an effective modality for evaluating a range of metabolic functions including glucose and fatty acid uptake, oxygen consumption and renal perfusion. Multiple positron emitting radiolabeled racers can be used for renal imaging in clinical settings. PET imaging thus holds the potential to improve the diagnosis of renal disorders, and to monitor disease progression and treatment response. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 26, 2021 Category: Radiology Source Type: research
Development of nuclear medicine in Africa
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 25, 2021 Category: Radiology Source Type: research
Can visual illustrations transform the patient information sheet for PET/MR neuroimaging studies into an engaging and interesting reading?
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 5, 2021 Category: Radiology Source Type: research
The utility of PET imaging in the diagnosis and management of psychosis: a brief review
ConclusionMolecular imaging has become a useful tool in the diagnosis and management of psychosis. Further work must be done to improve the comparative prognostic value and diagnostic accuracy of different radiotracers. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 2, 2021 Category: Radiology Source Type: research
Emerging applications of imaging in glioma: focus on PET/MRI and radiomics
ConclusionsPublished literature suggests a high potential for PET/MRI-derived radiomics. However, these results are based on small datasets and need to be further investigated in large prospective studies. Multidisciplinary efforts and multicenter collaborations will be essential to achieve these aims in the next future. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 2, 2021 Category: Radiology Source Type: research
Letter to the Editor: Timing of diuretics in diuresis renography
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - October 1, 2021 Category: Radiology Source Type: research
18F-FDG PET/MRI in endometrial cancer: systematic review and meta-analysis
ConclusionsPreliminary results demonstrated how18F-FDG PET/MRI could be a valid imaging technique in patients with EC, both in staging and restaging, also considering the limited radiation exposure. From the limited availability of the existing literature, it is clear that further prospective trials on larger and homogeneous cohorts are needed. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - September 23, 2021 Category: Radiology Source Type: research
89Zr-PET imaging in humans: a systematic review
Conclusions89Zr has shown to be a powerful PET-imaging tool, in particular for radiolabeling antibodies in order to study antigen expression, biodistribution, anticancer treatment planning and follow-up. Other than oncologic applications,89Zr-radiolabeled antibodies have been proposed for use in inflammatory and autoimmune disorders with interesting results.89Zr-labeled nanoparticles represent groundbreaking radiopharmaceuticals with potential huge fields of application. To evaluate the clinical usefulness of89Zr PET-imaging in different conditions and in real-world settings, and to widen its use in clinical practice, furt...
Source: Clinical and Translational Imaging - September 4, 2021 Category: Radiology Source Type: research
