The role of 68Ga-Pentixafor PET in multiple myeloma
ConclusionThere is very limited literature on the clinical application of68Ga-Pentixafor PET in MM patients, and this study provides a preliminary idea for the use of68Ga-Pentixafor PET in MM patients. Although68Ga-Pentixafor PET cannot yet be used as an alternative imaging modality to18F-FDG PET in MM patients,68Ga-Pentixafor may represent a valuable molecular probe for non-invasive assessment of CXCR4 expressed by tumor cells, and thus more prospective trials may be needed in the future to further explore the potential of68Ga -Pentixafor PET in MM imaging. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - May 22, 2023 Category: Radiology Source Type: research
Correction: Impact of 18F-FDG PET on the management of recurrent breast cancer: a meta-analysis
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - May 10, 2023 Category: Radiology Source Type: research
The diagnostic performance of [18F]FET PET/MRI versus [18F]FDG PET/MRI for recurrent glioma: a systematic review and meta-analysis
Conclusions[18F]FET PET/MRI has a higher AUC compared to [18F]FDG PET/MRI in the detection of tumor recurrence in glioma. However, the results of the meta-analysis were drawn from studies with small samples. Further larger prospective studies in this setting are warranted. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - May 9, 2023 Category: Radiology Source Type: research
Radiation exposure to family members of patients treated with radioactive iodine (131I): a systematic review and meta-analysis
Conclusion There are considerable radiation protection considerations for the family members of patients after radioiodine administration. The results of this study showed that caregivers received doses of less than 1 mSv. There are no radiation hazards for family members of patients treated with131I and the conventional advice provided by the radiation protection advisor is enough. The socioeconomic factors, lifestyle, and literacy levels of the patients ’ family members determined the compliance of the caregivers with safety recommendations and therefore modifies the doses received by family members. (Source: Clinica...
Source: Clinical and Translational Imaging - May 7, 2023 Category: Radiology Source Type: research
Detailed preoperative lymphatic mapping by lymphoscintigraphy for sentinel node identification: a pictorial essay
AbstractPre-operative lymphatic mapping for sentinel node identification is essential for accurate staging in patients with several solid cancers and for important prognostic implications.99mTc-labelled colloid lymphoscintigraphy and intraoperative sentinel lymph node detection using a gamma probe represent a well-established nuclear medicine technique and a detailed imaging method thanks to the advent of hybrid multi-modality SPET/CT. Through the description of numerous clinical cases, different in terms of cancer type and fields of application, we aimed to bring out the strengths and advantages of pre-operative lymphosci...
Source: Clinical and Translational Imaging - May 6, 2023 Category: Radiology Source Type: research
CZT SPECT study and the imaging of coronary disease: state of art
AbstractIn the last decade, single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) has been characterized by relevant technological innovations, with relevant improvements of both software and hardware settings, having the main goal of establishing systems with higher sensitivity and resolution, and with the potential to allow high quality images despite a more favorable dosimetry. In this regard, the introduction of dedicated cardiac cameras equipped with high-efficiency Cadmium –Zinc–Telluride (CZT) detectors have represented a milestone, allowing the unprecedented reduction of acquisit...
Source: Clinical and Translational Imaging - May 3, 2023 Category: Radiology Source Type: research
Sentinel node mapping in conjunctival and eyelid malignancies: a mini-review
ConclusionRadioguided SNB can be considered a feasible and safe procedure for conjunctival and eyelid malignancies, which could provide prognostic information for the treatment choice. Further confirmation in larger cohorts and longer follow-up periods is required to establish and validate this role. Finally, standardisation of the procedure would be useful. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - April 30, 2023 Category: Radiology Source Type: research
Role of PET gamma detection in radioguided surgery: a systematic review
ConclusionsRegardless of the intraoperative devices, RGS with positron emitters seems to lead to significant improvements in surgeons ’ ability to obtain a complete resection of tumors, even if the nature of photons resulting from positron–electron collision still remains extremely challenging and requires further technical advances. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - April 22, 2023 Category: Radiology Source Type: research
Robotic radioguided surgery: toward full integration of radio- and hybrid-detection modalities
ConclusionRobotic radioguidance procedures provide specific challenges, but at the same time create a significant growth potential for both image-guided surgery and interventional nuclear medicine. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - April 22, 2023 Category: Radiology Source Type: research
Prostate-specific membrane antigen (PSMA) radioguided surgery in prostate cancer: An overview of current application and future perspectives
AbstractRadical prostatectomy (RP) with or without pelvic lymph node dissection (PLND) is the most frequent approach to treat men affected by prostate cancer (PCa), together with primary radiotherapy. Generally, patients performed computed tomography (CT) and bone scintigraphy to stage the disease prior to surgery. However, specific inhibitors directed to the prostate-specific membrane antigen (PSMA) have been recently proposed as radiopharmaceutical for positron emission tomography (PET) imaging. PSMA-PET proved higher diagnostic accuracy to stage high-risk PCa compared to conventional imaging, even if its impact on overa...
Source: Clinical and Translational Imaging - April 19, 2023 Category: Radiology Source Type: research
Correction: Actionable imaging findings in the daily PET/CT scenario
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - April 3, 2023 Category: Radiology Source Type: research
Correction to: Repeated amino acid PET imaging for longitudinal monitoring of brain tumors
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - April 3, 2023 Category: Radiology Source Type: research
Measures of performance for sentinel lymph node biopsy in oro-oropharyngeal squamous cell carcinoma: a systematic review and meta-analysis
ConclusionsThe superiority of SPECT/CT over planar methods has been reported for providing identification of SLNs by aberrant lymphatic drainage. The additional contribution of optical tracers (mainly represented by blue dye) to the radiocolloid-based techniques did not improve significantly the measures of performance. (Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 29, 2023 Category: Radiology Source Type: research
Something old has become new: PET imaging of neural-crest tumors with [18F]-meta-fluorobenzylguanidine
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 29, 2023 Category: Radiology Source Type: research
About disruptive innovations in radioguided precision surgery
(Source: Clinical and Translational Imaging)
Source: Clinical and Translational Imaging - March 26, 2023 Category: Radiology Source Type: research
