Patient-Specific Quantitative In-Vivo Assessment of Human Mitral Valve Leaflet Strain Before and After MitraClip Repair
ConclusionsThe pre-operative MV leaflet strain patterns varied considerably across the range of MR disease states and after MitraClip repair. Despite large inter-patient heterogeneity, the post-operative deformation appears principally dictated by the pre-operative deformation state. This novel finding suggests that though the variation in MR functional state and MitraClip-induced deformation were substantial, the post-operative state can be predicted from the pre-operative data alone. This study suggests that, with use of larger patient cohort and corresponding long-term outcomes, quantitative predictive factors of MitraC...
Source: Cardiovascular Engineering and Technology - September 5, 2023 Category: Cardiology Source Type: research

Reconstruction and Validation of Arterial Geometries for Computational Fluid Dynamics Using Multiple Temporal Frames of 4D Flow-MRI Magnitude Images
ConclusionThis proof-of-concept study demonstrated that functional 4D Flow-MRI information can be utilized to retrospectively generate anatomical information for CFD models in the absence of standard imaging datasets and intravenous contrast. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - August 31, 2023 Category: Cardiology Source Type: research

Is Accurate Lumen Segmentation More Important than Outlet Boundary Condition in Image-Based Blood Flow Simulations for Intracranial Aneurysms?
ConclusionWith a more realistic lumen segmentation, the influence of the BC on the resulting hemodynamics is decreased. A realistic lumen segmentation can be ensured, e.g., by using high-resolved 2D images. Furthermore, the selection of an advanced outflow-splitting model is advised and the use of a zero-pressure BC and BC based on Murray ’s law with exponent n = 3 should be avoided. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - August 15, 2023 Category: Cardiology Source Type: research

Tracking of Blood Vessels Motion from 4D-flow MRI Data
AbstractThis paper presents a novel approach to track objects from 4D-flow MRI data. A salient feature of the proposed method is that it fully exploits the geometrical and dynamical nature of the information provided by this imaging modality. The underlying idea consists in formulating the tracking problem as a data assimilation problem, in which both position and velocity observations are extracted from the 4D-flow MRI data series. Optimal state estimation is then performed in a sequential fashion via Kalman filtering. The capabilities of the method are extensively assessed in a numerical study involving synthetic and cli...
Source: Cardiovascular Engineering and Technology - August 14, 2023 Category: Cardiology Source Type: research

Transcatheter Pulmonary Artery Banding in High-Risk Neonates: In-Vitro Study Provoked by Initial Clinical Experience
ConclusionDevice oversizing, with appropriate adjustment to fenestration size, may reduce migration risk and provide a clinically appropriate balance between resulting pressure gradient and Qp:Qs. Our results can guide the interventionalist in appropriately selecting the device and fenestrations based on patient-specific anatomy and desired post-implantation flow characteristics. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - August 14, 2023 Category: Cardiology Source Type: research

Hybrid Cathode Lithium Battery Discharge Simulation for Implantable Cardioverter Defibrillators Using a Coupled Electro-Thermal Dynamic Model
AbstractThis paper explores the effect of the load imposed by implantable cardioverter defibrillators (ICDs) on their lithium battery power sources longevity using a simulation approach that incorporates a coupled electro-thermal dynamic model. ICDs are one of the effective treatments available to significantly improve survival of patients with fatal arrhythmia (abnormal heart rhythm) disorders. Using a lithium battery power source, this life-saving device sends electrical shocks or pulses to regulate the heartbeat. The service life and reliability of an ICD is primarily expressed by its battery ’s lifespan and performan...
Source: Cardiovascular Engineering and Technology - August 11, 2023 Category: Cardiology Source Type: research

Blood Viscosity Biosensor Based on Electromagnetic Resonator
ConclusionThe exact design of the proposed sensor and its experimental results are presented using a prototype for some liquids that indicate the sensor precision. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - August 11, 2023 Category: Cardiology Source Type: research

Extraction and Digitization of ECG Signals from Standard Clinical Portable Document Format Files for the Principal Component Analysis of T-wave Morphology
ConclusionThis study presents a straightforward method for re-digitizing ECGs stored in the PDF format utilized in many academic electronic medical record systems. This process can yield re-digitized lead specific signals which can be retrospectively analyzed using advanced custom post-processing numerical analysis independent of commercially available platforms. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 25, 2023 Category: Cardiology Source Type: research

Correction: Fabrication of Low-Cost Patient-Specific Vascular Models for Particle Image Velocimetry
(Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 25, 2023 Category: Cardiology Source Type: research

Numerical Study of a Thrombus Migration Risk in Aneurysm After Coil Embolization in Patient Cases: FSI Modelling
ConclusionsThe proposed methodology allows evaluating the clot migration risk, vital for evaluating the progress after endovascular interventions, it is a step forward in the personalized medicine, patient follow-up, and helping the medical team deciding the optimal treatment.Graphical Abstract (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - July 19, 2023 Category: Cardiology Source Type: research

The Relation Between Viscous Energy Dissipation and Pulsation for Aortic Hemodynamics Driven by a Left Ventricular Assist Device
AbstractLeft ventricular assist device (LVAD) provides mechanical circulatory support for patients with advanced heart failure. Treatment using LVAD is commonly associated with complications such as stroke and gastro-intestinal bleeding. These complications are intimately related to the state of hemodynamics in the aorta, driven by a jet flow from the LVAD outflow graft that impinges into the aorta wall. Here we conduct a systematic analyses of hemodynamics driven by an LVAD with a specific focus on viscous energy transport and dissipation. We conduct a complementary set of analysis using idealized cylindrical tubes with d...
Source: Cardiovascular Engineering and Technology - June 20, 2023 Category: Cardiology Source Type: research

Intra-Cardiac Flow from Geometry Prescribed Computational Fluid Dynamics: Comparison with Ultrasound Vector Flow Imaging
ConclusionThe direct comparison of flow patterns shows that the proposed CFD pipeline provide realistic flow patterns in a well-controlled experimental setup. The demanded accuracy is obtained close to the inlet and outlet, but not in locations far from these. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 15, 2023 Category: Cardiology Source Type: research

A Vector Fitting Approach for the Automated Estimation of Lumped Boundary Conditions of 1D Circulation Models
ConclusionResults suggest that the proposed method is able to accurately estimate boundary conditions of arbitrary order. Higher order boundary conditions can improve the accuracy of cardiovascular simulations, and Time-Domain Vector Fitting can automatically estimate them. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - June 12, 2023 Category: Cardiology Source Type: research

Advances in Design and Development of Lumi-Solve: A Novel Drug-Eluting Photo-Angioplasty Device
ConclusionsTo avoid use of the GW port and its associated complications a dedicated third port and lumen for the Lumi-Solve fibre-optic may be required. To maximize balloon surface chemical and biological photo-activation, non-parallel, intra-balloon, fibre-optic lumen trajectories, including a spiral design may be useful. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - May 10, 2023 Category: Cardiology Source Type: research

Optimization of 4D Flow MRI Spatial and Temporal Resolution for Examining Complex Hemodynamics in the Carotid Artery Bifurcation
ConclusionA spatial resolution of 0.74 –1.00  mm3 and a temporal resolution of 23 –48 ms (1–2 k-space segments) provides a 4D flow MRI protocol capable of imaging velocity and TAWSS in regions of complex flow within the carotid bifurcation at a clinically acceptable scan time. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - May 8, 2023 Category: Cardiology Source Type: research