Cardiovascular Engineering and Technology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A Brush –Spin–Coating Method for Fabricating In Vitro Patient-Specific Vascular Models by Coupling 3D-Printing
ConclusionThrough the brush –spin–coating method, models of different sizes and complexity with prescribed thickness can be manufactured, which will be helpful for developing surgical treatment strategies or training neuroendovascular interventionalists. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 2, 2020 Category: Cardiology Source Type: research

Modeling of Virtual Mechanical Circulatory Hemodynamics for Biventricular Heart Failure Support
ConclusionsThis initialin silico study demonstrated that use of the P-CFTAH as a BVAD supports cardiac output and arterial pressure in biventricular heart failure conditions. A similar but larger device would be required for a large adult patient who needs more than 5 L/min of support. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 19, 2020 Category: Cardiology Source Type: research

First Expert Evaluation of a New Steerable Catheter in an Isolated Beating Heart
ConclusionsThe expert user found the passive beating heart setup to more successful than the active beating heart setup for the purpose of this experiment, with insightful visualization while the heart was in beating condition. The steerability of the prototypes was experienced as useful and clinically relevant. Based on the questionnaires and interview we were able to identify future design improvements and developments for the steerable catheter prototypes. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 18, 2020 Category: Cardiology Source Type: research

Hydrodynamics in Acute Ischemic Stroke Catheters Under Static and Cyclic Aspiration Conditions
ConclusionFor future investigations of cyclic aspiration AIS therapy, the best options are to use large inner diameter and low compliance catheters operating at lower cyclic frequencies to generate the greatest mean and oscillating forces on lodged thromboemboli. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 18, 2020 Category: Cardiology Source Type: research

In Vitro Study of a Stentless Aortic Bioprosthesis Made of Bacterial Cellulose
ConclusionsTheV3 model of the aortic valve prosthesis is the most effective.In vivo tests using BC as a structural material for this model are recommended. The response time of theV3 model to changed work conditions is comparable to that of a healthy human heart. The model functions as an aortic valve prosthesis inin vitro conditions. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 17, 2020 Category: Cardiology Source Type: research

Annular Dynamics and Leaflet Geometry in Patch Reconstruction of the Posterior Mitral Leaflet After Adding a Flexible Annuloplasty Ring
ConclusionsThe flexible annuloplasty ring resulted in a downsized annulus with restriction of cyclic annular changes in the reconstructed mitral valve. Ring insertion preserved the annular saddle shape and coaptation length. The ring annuloplasty counteracted the non-physiological annular dynamics, and this may improve durability of the posterior mitral leaflet patch reconstruction. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 16, 2020 Category: Cardiology Source Type: research

Neural Network Vessel Lumen Regression for Automated Lumen Cross-Section Segmentation in Cardiovascular Image-Based Modeling
ConclusionBy employing our models in a pathline-based cardiovascular model building pipeline we substantially reduce the manual segmentation effort required to build accurate cardiovascular models, and reduce the overall time required to perform patient-specific cardiovascular simulations. While our method is applied here for cardiovascular model building it is generally applicable to segmentation of tree-like and tubular structures from image data. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 11, 2020 Category: Cardiology Source Type: research

Effect of Geometric Accuracy at the Proximal Landing Zone on Simulation Results for Thoracic Endovascular Repair Patients
ConclusionsThe flow pattern and hemodynamic parameter distributions were affected by the geometric accuracy only in a small region near the proximal landing zone. The flow split was hardly affected by the LSA partial coverage, indicating that the coverage may have slight effects on short-term blood perfusion. However, this conclusion needs to be verified in future studies with larger sample sizes. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - November 3, 2020 Category: Cardiology Source Type: research

Overview of the Whole Heart and Heart Chamber Segmentation Methods
ConclusionThe methods described are classified based on the used segmentation approach into (1) edge-based segmentation methods, (2) model-fitting segmentation methods and (3) machine and deep learning segmentation methods and are further split based on the targeted cardiac structure. Edge-based methods are mostly developed as semi-automatic and allow end-user interaction, which provides physicians with extra control over the final segmentation. Model-fitting methods are very robust and resistant to the high variability in image contrast and overall image quality. Nevertheless, they are often time-consuming and require app...
Source: Cardiovascular Engineering and Technology - November 2, 2020 Category: Cardiology Source Type: research

Transcellular Model for Neutral and Charged Nanoparticles Across an In Vitro Blood –Brain Barrier
ConclusionOur model can be used to predict the optimal size and charge of the NPs and the optimal charge of the BBB for an optimal systemic drug delivery strategy to the brain. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 28, 2020 Category: Cardiology Source Type: research

Long-Term Arterial Remodeling After Bioresorbable Scaffold Implantation 4-Year Follow-up of Quantitative Coronary Angiography, Histology and Optical Coherence Tomography
ConclusionAt 4 years, the scaffold struts were completely embedded into vessel wall and mostly replaced by regenerated tissue. There was no sign of in-stent stenosis in all stented arteries. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 27, 2020 Category: Cardiology Source Type: research

Patient-Specific Hemodynamics of New Coronary Artery Bypass Configurations
ConclusionThe virtual surgical configurations have the potential to improve the quality of operation by providing quantitative surgical insight. The degree of stenosis is a critical factor in terms of coronary perfusion and WSS. The sequential anastomosis can be done safely if the anastomosis angle is less than 90 degrees regardless of degree of stenosis. The smaller proposed perfusion index value,O(0.04  − 0) × 102, enable us to quantify the post-op hemodynamic performance by comparing with the ideal healthy physiological flow. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 13, 2020 Category: Cardiology Source Type: research

Ultrasound Based Computational Fluid Dynamics Assessment of Brachial Artery Wall Shear Stress in Preeclamptic Pregnancy
ConclusionCreating 3D artery geometries from 2D ultrasound images can be used for CFD simulations to calculate WSS from ultrasound without assuming cylindrical arteries. This approach requires minimal time for both medical imaging and CFD analysis. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 5, 2020 Category: Cardiology Source Type: research

Radiopacity of Coronary Stents, an In Vitro Comparative Study
ConclusionThis study highlighted significant differences in the radiopacity of coronary stents deployed in a bench test model. The strut thickness and the presence of platinum increased the radiopacity. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - October 5, 2020 Category: Cardiology Source Type: research

The Glycocalyx and Pressure-Dependent Transcellular Albumin Transport
ConclusionPressure-dependent albumin uptake and transcellular transport is another component of endothelial mechanotransduction and associated regulation of solute flux. This novel albumin uptake and transport pathway is regulated by heparan sulfates and eNOS. Albumin uptake is sensitive to ROS. The physiological and clinical implications of this albumin transport are discussed. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - September 30, 2020 Category: Cardiology Source Type: research