Cardiovascular Engineering and Technology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

In Vivo Intravascular Optical Coherence Tomography (IVOCT) Structural and Blood Flow Imaging Based Mechanical Simulation Analysis of a Blood Vessel
ConclusionThis study provides a solution to the difficulty of getting inlet flow boundary for numerical simulation of arteries. It paves the way for developing IVOCT based vascular stress analysis and imaging methods for the studies and diagnosis of vascular diseases. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - February 2, 2022 Category: Cardiology Source Type: research

In Vitro Pressure Measurements Across an Interatrial Shunt for HFpEF Treatment
ConclusionsThe flow rate/pressure drop relationship across an in vitro model of an interatrial shunt has been measured for a variety of physiologically relevant cases. Among other things, the results suggest that steady flow approximations to the heart ’s pulsatile flow should be used with caution and simplified theoretical models do not approximate the flow rate/pressure drop relationship accurately. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - February 1, 2022 Category: Cardiology Source Type: research

Challenges in Modeling Hemodynamics in Cerebral Aneurysms Related to Arteriovenous Malformations
ConclusionsThe presented work offers insight on the impact of distal AVMs on aneurysmal wall shear stress using physiologically realistic computational models. Patient-specific modeling of hemodynamics in aneurysms and associated AVMs has great potential for understanding lesion pathogenesis, surgical planning, and assessing the effect of treatment of one lesion relative to another. However, we show that modeling approaches cannot usually meaningfully quantify the impact of AVMs if based solely on imaging data from CT and X-ray angiography, currently used in clinical practice. Based on recent studies, it appears that 4D fl...
Source: Cardiovascular Engineering and Technology - February 1, 2022 Category: Cardiology Source Type: research

Inadequacy of Augmentation Index for Monitoring Arterial Stiffness: Comparison with Arterial Compliance and Other Hemodynamic Variables
ConclusionAIx is neither linearly correlated with arterial stiffness, nor with arterial compliance and several cardiac and arterial parameters have to be considered when AIx is calculated. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 31, 2022 Category: Cardiology Source Type: research

Experimental and Mouse-Specific Computational Models of the Fbln4SMKO Mouse to Identify Potential Biomarkers for Ascending Thoracic Aortic Aneurysm
ConclusionThe results highlight potential biomarkers of ATAA outcomes that can be obtained through noninvasive imaging and computational simulations, and they illustrate the potential synergy between small-animal and computational models. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 22, 2022 Category: Cardiology Source Type: research

An Accelerated Thrombosis Model for Computational Fluid Dynamics Simulations in Rotary Blood Pumps
ConclusionThe concentration of activated platelets can be used as a surrogate and computationally low-cost marker to determine potential risk regions of thrombus deposition in a blood pump. Relative comparisons of thrombus risk are possible even considering the intrinsic uncertainty in model parameters and operating conditions. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 14, 2022 Category: Cardiology Source Type: research

Development of Inspired Therapeutics Pediatric VAD: Computational Analysis and Characterization of VAD V3
ConclusionsThe initial computational characterization of the Inspired Pediatric VAD V3 is encouraging and future work will include device prototype testing in a mock circulatory loop and acute large animal model. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 10, 2022 Category: Cardiology Source Type: research

Deep Learning to Automatically Segment and Analyze Abdominal Aortic Aneurysm from Computed Tomography Angiography
ConclusionThe developed deep learning models can effectively segment the thrombus from patients affected by AAA. Moreover, the diameters automatically extracted from the AAA show high correlation with those manually measured by experts.Graphical abstract (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 8, 2022 Category: Cardiology Source Type: research

A Mechanistic Lumped Parameter Model of the Berlin Heart EXCOR to Analyze Device Performance and Physiologic Interactions
ConclusionWe present a novel, mechanistic model that can be readily adjusted to study a wide range of device settings and clinical scenarios. Physiologic interactions between the BH and the native LV produced large variability in cardiac loading. Our findings showed that operating the BH at a device rate greater than the patient ’s native heart decreases variability in physiological interactions between the BH and LV, increasing cardiac offloading while maintaining cardiac output. Device rates that are close to the resting heart rate may result in unfavorable cardiac loading conditions. Our work demonstrates the utility ...
Source: Cardiovascular Engineering and Technology - January 7, 2022 Category: Cardiology Source Type: research

Semi-Automatic Reconstruction of Patient-Specific Stented Coronaries based on Data Assimilation and Computer Aided Design
ConclusionsThe method presented here has a high level of automation and excellent accuracy performances, so it can be used for larger studies involving patient-specific geometries. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 7, 2022 Category: Cardiology Source Type: research

Correction to: Predictive Model for Thrombus Formation After Transcatheter Valve Replacement
(Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 7, 2022 Category: Cardiology Source Type: research

A CNN Model for Cardiac Arrhythmias Classification Based on Individual ECG Signals
ConclusionThe evaluation indicates that our proposed approach, which performs well on both original signals and de-noised signals, fits well with wearable ECG monitoring and applications. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - January 3, 2022 Category: Cardiology Source Type: research

Predictive Model for Thrombus Formation After Transcatheter Valve Replacement
ConclusionA predictive model relating likelihood of valve thrombosis usingГ in the NS was developed with promising sensitivity and specificity. With further studies and improvements, this predictive technology may lead to alerting physicians on the risk for thrombus formation following TAVR. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 2, 2021 Category: Cardiology Source Type: research

The Mitochondrial-Derived Peptide MOTS-c Attenuates Oxidative Stress Injury and the Inflammatory Response of H9c2 Cells Through the Nrf2/ARE and NF- κB Pathways
ConclusionsOur investigation indicated that MOTS-c could protect against H2O2-induced inflammation and oxidative stress in H9c2 cells by inhibiting NF- κB and activating the Nrf2/ARE pathways. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 2, 2021 Category: Cardiology Source Type: research

Right Heart Morphology of Candidate Patients for Transcatheter Tricuspid Valve Interventions
ConclusionsThis study provides new and further insight to the right heart morphology and functional characteristics of candidate patients for a transcatheter tricuspid valve intervention. These data provide a platform from which these patients can continue to be better understood for further improving transcatheter system design and use. (Source: Cardiovascular Engineering and Technology)
Source: Cardiovascular Engineering and Technology - December 1, 2021 Category: Cardiology Source Type: research