High-density lipoproteins attenuate high glucose-impaired endothelial cell signaling and functions: potential implications for improved vascular repair in diabetes
Abnormalities of endothelial cell function are proposed to be a critical factor underlying adverse cardiovascular outcomes in the setting of hyperglycaemia. While high-density lipoproteins (HDL) have been demo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2017 Category: Cardiology Authors: Xing Chen, My-Ngan Duong, Peter J. Psaltis, Christina A. Bursill and Stephen J. Nicholls Tags: Original investigation Source Type: research

Oxidative stress and inflammation as central mediators of atrial fibrillation in obesity and diabetes
Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia in humans. Several risk factors promote AF, among which diabetes mellitus has emerged as one of the most important. The growing recognit... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2017 Category: Cardiology Authors: Basil S. Karam, Alejandro Chavez-Moreno, Wonjoon Koh, Joseph G. Akar and Fadi G. Akar Tags: Review Source Type: research

NTproBNP in insulin-resistance mediated conditions: overweight/obesity, metabolic syndrome and diabetes. The population-based Casale Monferrato Study
NTproBNP and BNP levels are reduced in obese subjects, but population-based data comparing the pattern of this relationship in the full spectrum of insulin-resistance mediated conditions, overweight/obesity, m... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 25, 2017 Category: Cardiology Authors: Stefano Baldassarre, Salvatore Fragapani, Antonio Panero, Debora Fedele, Silvia Pinach, Manuela Lucchiari, Anna Rita Vitale, Giulio Mengozzi, Gabriella Gruden and Graziella Bruno Tags: Original investigation Source Type: research

Erratum to: Changes in proteinuria and the risk of myocardial infarction in people with diabetes or pre-diabetes: a prospective cohort study
Following publication of the original article [1], the authors reported that figure  2 had not been replaced with the correct figure as indicated in the proofs. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 19, 2017 Category: Cardiology Authors: Anxin Wang, Yang Sun, Xiaoxue Liu, Zhaoping Su, Junjuan Li, Yanxia Luo, Shuohua Chen, Jianli Wang, Xia Li, Zhan Zhao, Huiping Zhu, Shouling Wu and Xiuhua Guo Tags: Erratum Source Type: research

Circulating levels and characterization of microparticles in patients with different degrees of glucose tolerance
Microparticles (MPs) are vesicular structures shed from endothelial or circulating blood cells, after activation or apoptosis, and can be considered markers of vascular damage. We aimed to determine the levels... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 19, 2017 Category: Cardiology Authors: Alessandra Giannella, Claudia Maria Radu, Lorenzo Franco, Elena Campello, Paolo Simioni, Angelo Avogaro, Saula Vigili de Kreutzenberg and Giulio Ceolotto Tags: Original investigation Source Type: research

High density lipoprotein modulates osteocalcin expression in circulating monocytes: a potential protective mechanism for cardiovascular disease in type 1 diabetes
Cardiovascular disease (CVD) is a major cause of mortality in type 1 diabetes (T1D). A pro-calcific drift of circulating monocytes has been linked to vascular calcification and is marked by the surface express... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 16, 2017 Category: Cardiology Authors: Ernesto Maddaloni, Yu Xia, Kyoungmin Park, Stephanie D ’Eon, Liane J. Tinsley, Ronald St-Louis, Mogher Khamaisi, Qian Li, George L. King and Hillary A. Keenan Tags: Original investigation Source Type: research

Evolution and bad prognostic value of advanced glycation end products after acute heart failure: relation with body composition
The role of advanced glycation end products (AGEs) and their soluble receptor (sRAGE) on the progression and prognosis of acute heart failure (HF) was analysed in relation with metabolic parameters as body com... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 15, 2017 Category: Cardiology Authors: Beatriz Paradela-Dobarro, Ángel Fernández-Trasancos, Diana Bou-Teen, Sonia Eiras, Rocío González-Ferreiro, Rosa M. Agra, Alfonso Varela-Román, Ana I. Castro-Pais, Marcos C. Carreira, Felipe F. Casanueva, Ezequiel Álvarez and José R. González-Juana Tags: Original investigation Source Type: research

The impact of cardiovascular co-morbidities and duration of diabetes on the association between microvascular function and glycaemic control
Good glycaemic control in type 2 diabetes (T2DM) protects the microcirculation. Current guidelines suggest glycaemic targets be relaxed in advanced diabetes. We explored whether disease duration or pre-existin... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 15, 2017 Category: Cardiology Authors: F. Casanova, D. D. Adingupu, F. Adams, K. M. Gooding, H. C. Looker, K. Aizawa, F. Dove, S. Elyas, J. J. F. Belch, P. E. Gates, R. C. Littleford, M. Gilchrist, H. M. Colhoun, A. C. Shore, F. Khan and W. D. Strain Tags: Original investigation Source Type: research

Nonclinical and clinical pharmacology evidence for cardiovascular safety of saxagliptin
In the Saxagliptin Assessment of Vascular Outcomes Recorded in Patients with Diabetes Mellitus (SAVOR) trial in patients with type 2 diabetes mellitus (T2D) at high risk of cardiovascular (CV) disease, saxagli... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 13, 2017 Category: Cardiology Authors: Pia S. Pollack, Kristina D. Chadwick, David M. Smith, Martin Billger, Boaz Hirshberg, Nayyar Iqbal and David W. Boulton Tags: Review Source Type: research

Association between carotid plaque characteristics and acute cerebral infarction determined by MRI in patients with type 2 diabetes mellitus
Type 2 diabetes mellitus (T2DM) might aggravate the carotid plaque vulnerability, and increase the risk for ischemic stroke. Few studies reported the acute stroke subtype with carotid plaque characteristics in... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 11, 2017 Category: Cardiology Authors: Beibei Sun, Xiao Li, Xiaosheng Liu, Xiaoqian Ge, Qing Lu, Xihai Zhao, Jun Pu, Jianrong Xu and Huilin Zhao Tags: Original investigation Source Type: research

A randomized, placebo-controlled study of the cardiovascular safety of the once-weekly DPP-4 inhibitor omarigliptin in patients with type 2 diabetes mellitus
Omarigliptin is a once-weekly (q.w.) oral DPP-4 inhibitor that is approved for the treatment of patients with type 2 diabetes mellitus (T2DM) in Japan. To support approval of omarigliptin in the United States,... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 11, 2017 Category: Cardiology Authors: Ira Gantz, Menghui Chen, Shailaja Suryawanshi, Catherine Ntabadde, Sukrut Shah, Edward A. O ’Neill, Samuel S. Engel, Keith D. Kaufman and Eseng Lai Tags: Original investigation Source Type: research

The effect of exercise training on clinical outcomes in patients with the metabolic syndrome: a systematic review and meta-analysis
Purpose: to establish if exercise training improves clinical outcomes in people with metabolic syndrome (MetS). Registered with PROSPERO international prospective register of systemati... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 30, 2017 Category: Cardiology Authors: C. Ostman, N. A. Smart, D. Morcos, A. Duller, W. Ridley and D. Jewiss Tags: Original investigation Source Type: research

Inverse associations between serum levels of secreted frizzled-related protein-5 (SFRP5) and multiple cardiometabolic risk factors: KORA F4 study
Secreted frizzled-related protein (Sfrp)5 has beneficial effects on insulin sensitivity, inflammation and cardiovascular risk in different mouse models, but its relevance for cardiometabolic diseases in humans... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 29, 2017 Category: Cardiology Authors: Maren Carstensen-Kirberg, Julia M. Kannenberg, Cornelia Huth, Christa Meisinger, Wolfgang Koenig, Margit Heier, Annette Peters, Wolfgang Rathmann, Michael Roden, Christian Herder and Barbara Thorand Tags: Original investigation Source Type: research

Relationship between the triglyceride glucose index and coronary artery calcification in Korean adults
The triglyceride glucose (TyG) index has been considered a simple surrogate marker of insulin resistance. However, few studies have investigated the relationship between the TyG index and coronary artery calci... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 23, 2017 Category: Cardiology Authors: Min Kyung Kim, Chul Woo Ahn, Shinae Kang, Ji Sun Nam, Kyung Rae Kim and Jong Suk Park Tags: Original investigation Source Type: research

Effects of background statin therapy on glycemic response and cardiovascular events following initiation of insulin therapy in type 2 diabetes: a large UK cohort study
Statins may increase the risk of new-onset diabetes and adversely affect glycaemic control, but their effects on the glycemic response and mortality outcomes following commencement of insulin therapy in patien... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 22, 2017 Category: Cardiology Authors: Uchenna Anyanwagu, Jil Mamza, Richard Donnelly and Iskandar Idris Tags: Original investigation Source Type: research

Contribution of serum FGF21 level to the identification of left ventricular systolic dysfunction and cardiac death
This study aimed to investigate the relationship between FGF21 and left vent... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 18, 2017 Category: Cardiology Authors: Yun Shen, Xueli Zhang, Xiaoping Pan, Yiting Xu, Qin Xiong, Zhigang Lu, Xiaojing Ma, Yuqian Bao and Weiping Jia Tags: Original investigation Source Type: research

New onset diabetes in adulthood is associated with a substantial risk for mortality at all ages: a population based historical cohort study with a decade-long follow-up
Diabetes has been reported to be associated with an increased relative risk for mortality, with estimates ranging from 1.1 to 2.1. Findings are inconsistent regarding modification of the risk by gender and by ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 15, 2017 Category: Cardiology Authors: Inbar Zucker, Tamy Shohat, Rachel Dankner and Gabriel Chodick Tags: Original investigation Source Type: research

Changes in proteinuria and the risk of myocardial infarction in people with diabetes or pre-diabetes: a prospective cohort study
The relationship between changes in proteinuria and myocardial infarction (MI) remains unclear in people with diabetes or pre-diabetes. We aimed to evaluate the predictive value and independent role of changes... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 15, 2017 Category: Cardiology Authors: Anxin Wang, Yang Sun, Xiaoxue Liu, Zhaoping Su, Junjuan Li, Yanxia Luo, Shuohua Chen, Jianli Wang, Xia Li, Zhan Zhao, Huiping Zhu, Shouling Wu and Xiuhua Guo Tags: Original investigation Source Type: research

Admission blood glucose and 10-year mortality among patients with or without pre-existing diabetes mellitus hospitalized with heart failure
High admission blood glucose (ABG) level has been associated with a poor short-term outcome among non-diabetic patients with heart failure (HF). We aimed to investigate the association between ABG levels and l... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 14, 2017 Category: Cardiology Authors: Osnat Itzhaki Ben Zadok, Ran Kornowski, Ilan Goldenberg, Robert Klempfner, Yoel Toledano, Yitschak Biton, Enrique Z. Fisman, Alexander Tenenbaum, Gregory Golovchiner, Ehud Kadmon, Alexander Omelchenko, Tuvia Ben Gal and Alon Barsheshet Tags: Original investigation Source Type: research

Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blind multicenter randomized control trial
We aimed to investigate the efficacy of ascorbic acid and acetylsalicylic acid among type II diabetes mellitus patients using metformin (only) for diabetes management therapy. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 14, 2017 Category: Cardiology Authors: Syed Wasif Gillani, Syed Azhar Syed Sulaiman, Mohi Iqbal Mohammad Abdul and Mirza R. Baig Tags: Original investigation Source Type: research

Selenoprotein S: a therapeutic target for diabetes and macroangiopathy?
Inflammatory response, oxidative stress, and endoplasmic reticulum (ER) stress are important pathophysiological bases of the occurrence and development of diabetes mellitus (DM) and macroangiopathy complicatio... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 10, 2017 Category: Cardiology Authors: Shan-shan Yu and Jian-ling Du Tags: Review Source Type: research

Gender differences in hospital admissions for major cardiovascular events and procedures in people with and without diabetes in England: a nationwide study 2004 –2014
Secondary prevention of cardiovascular disease (CVD) has improved immensely during the past decade but controversies persist on cardiovascular benefits among women with diabetes. We investigated 11-year trends... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 10, 2017 Category: Cardiology Authors: Anthony A. Laverty, Alex Bottle, Sung-Hee Kim, Bhakti Visani, Azeem Majeed, Christopher Millett and Eszter P. Vamos Tags: Original investigation Source Type: research

Neutrophil gelatinase associated lipocalin (NGAL) is elevated in type 2 diabetics with carotid artery stenosis and reduced under metformin treatment
Neutrophil gelatinase-associated lipocalin (NGAL), an acute phase protein released by neutrophils, has been described as biomarker of inflammatory states. Type 2 diabetes mellitus (T2DM) is characterized by in... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 8, 2017 Category: Cardiology Authors: W. Eilenberg, S. Stojkovic, A. Piechota-Polanczyk, A. Kaider, N. Kozakowski, W. J. Weninger, J. Nanobachvili, J. Wojta, I. Huk, S. Demyanets and C. Neumayer Tags: Original investigation Source Type: research

Impact of CD14++CD16+ monocytes on plaque vulnerability in diabetic and non-diabetic patients with asymptomatic coronary artery disease: a cross-sectional study
This study sought to investigate the impact of CD14++CD16+ ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 8, 2017 Category: Cardiology Authors: Naofumi Yoshida, Hiroyuki Yamamoto, Toshiro Shinke, Hiromasa Otake, Masaru Kuroda, Daisuke Terashita, Hachidai Takahashi, Kazuhiko Sakaguchi, Yushi Hirota, Takuo Emoto, Hilman Zulkifli Amin, Taiji Mizoguchi, Tomohiro Hayashi, Naoto Sasaki, Tomoya Yamashit Tags: Original investigation Source Type: research

Serum high mobility group box-1 and osteoprotegerin levels are associated with peripheral arterial disease and critical limb ischemia in type 2 diabetic subjects
High mobility group box-1 (HMGB-1) is a nuclear protein also acting as inflammatory mediator, whilst osteoprotegerin (OPG), member of tumor necrosis factor receptor superfamily, is indicated as marker of vascu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - August 8, 2017 Category: Cardiology Authors: Silvia Giovannini, Giovanni Tinelli, Federico Biscetti, Giuseppe Straface, Flavia Angelini, Dario Pitocco, Luciana Mucci, Raffaele Landolfi and Andrea Flex Tags: Original investigation Source Type: research

Heart failure hospitalization risk associated with use of two classes of oral antidiabetic medications: an observational, real-world analysis
The objective was to assess relative risk of heart failure hospitalization of... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 31, 2017 Category: Cardiology Authors: Santosh Gautam, Abiy Agiro, John Barron, Thomas Power, Harry Weisman and Jeff White Tags: Original investigation Source Type: research

Preclinical carotid atherosclerosis in patients with latent autoimmune diabetes in adults (LADA), type 2 diabetes and classical type 1 diabetes
LADA is probably the most prevalent form of autoimmune diabetes. Nevertheless, there are few data about cardiovascular disease in this group of patients. The aim of this study was to investigate the frequency ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 28, 2017 Category: Cardiology Authors: Marta Hern ández, Carolina López, Jordi Real, Joan Valls, Emilio Ortega-Martinez de Victoria, Federico Vázquez, Esther Rubinat, Minerva Granado-Casas, Nuria Alonso, Teresa Molí, Angels Betriu, Albert Lecube, Elvira Fernández, Richard David Leslie and Tags: Original investigation Source Type: research

Comparative effects of microvascular and macrovascular disease on the risk of major outcomes in patients with type 2 diabetes
Microvascular disease is associated with a high risk of macrovascular events in patients with type 2 diabetes, but the impact of macrovascular disease on the risk of microvascular events remains unknown. We so... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 27, 2017 Category: Cardiology Authors: Kamel Mohammedi, Mark Woodward, Michel Marre, Stephen Colagiuri, Mark Cooper, Stephen Harrap, Giuseppe Mancia, Neil Poulter, Bryan Williams, Sophia Zoungas and John Chalmers Tags: Original investigation Source Type: research

Circulating sortilin level as a potential biomarker for coronary atherosclerosis and diabetes mellitus
A previous genome-wide association study showed that a genetic variant of sortilin was associated with the risk of coronary artery disease (CAD). However, the role of circulating sortilin is still unknown. We ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 20, 2017 Category: Cardiology Authors: Tae Jung Oh, Chang Ho Ahn, Bo-Rahm Kim, Kyoung Min Kim, Jae Hoon Moon, Soo Lim, Kyong Soo Park, Cheong Lim, HakChul Jang and Sung Hee Choi Source Type: research

Mirroring the CANTOS revolution: is anti-inflammatory therapy for diabetes just around the corner?
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2017 Category: Cardiology Authors: Alexander Tenenbaum and Enrique Z. Fisman Source Type: research

Erratum to: Impact of metabolic syndrome and its components on heart rate variability during hemodialysis: a cross-sectional study
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 14, 2017 Category: Cardiology Authors: Yu-Ming Chang, Chih-Chung Shiao, Ya-Ting Huang, I-Ling Chen, Chuan-Lan Yang, Show-Chin Leu, Hung-Li Su, Jsun-Liang Kao, Shih-Ching Tsai, Rong-Na Jhen and Ching-Cherng Uen Source Type: research

Symmetric and asymmetric dimethylarginine as risk markers of cardiovascular disease, all-cause mortality and deterioration in kidney function in persons with type 2 diabetes and microalbuminuria
To evaluate symmetric dimethylarginine (SDMA) and asymmetric dimethylarginine (ADMA) as risk markers of cardiovascular disease, all-cause mortality and deterioration in renal function in a well characterised t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 11, 2017 Category: Cardiology Authors: Emilie H. Zobel, Bernt Johan von Scholten, Henrik Reinhard, Frederik Persson, Tom Teerlink, Tine W. Hansen, Hans-Henrik Parving, Peter K. Jacobsen and Peter Rossing Source Type: research

The impact of DPP-4 inhibitors on long-term survival among diabetic patients after first acute myocardial infarction
Previous studies regarding the cardioprotective effects of dipeptidyl peptidase 4 (DPP-4) inhibitors have not provided sufficient evidence of a relationship between DPP-4 inhibition and actual cardiovascular o... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 11, 2017 Category: Cardiology Authors: Mei-Tzu Wang, Sheng-Che Lin, Pei-Ling Tang, Wang-Ting Hung, Chin-Chang Cheng, Jin-Shiou Yang, Hong-Tai Chang, Chun-Peng Liu, Guang-Yuan Mar and Wei-Chun Huang Source Type: research

Joint analysis of left ventricular expression and circulating plasma levels of Omentin after myocardial ischemia
Omentin-1, also known as Intelectin-1 (ITLN1), is an adipokine with plasma levels associated with diabetes, obesity, and coronary artery disease. Recent studies suggest that ITLN1 can mitigate myocardial ische... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 7, 2017 Category: Cardiology Authors: Louis A. Saddic, Sarah M. Nicoloro, Olga T. Gupta, Michael P. Czech, Joshua Gorham, Stanton K. Shernan, Christine E. Seidman, Jon G. Seidman, Sary F. Aranki, Simon C. Body, Timothy P. Fitzgibbons and Jochen D. Muehlschlegel Source Type: research

Diabetic retinopathy is associated with diastolic dysfunction in type 2 diabetic patients with non-ischemic dilated cardiomyopathy
To investigate the association between diabetic retinopathy (DR) and myocardial dysfunction in patients with type 2 diabetes and dilated cardiomyopathy (dCMP). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Yoo-Ri Chung, Se-Jun Park, Ka Young Moon, Seoyoung Annie Choi, Hong-Seok Lim, Sung Wook Park, Jeong Hun Kim and Kihwang Lee Source Type: research

In vivo administration of urolithin A and B prevents the occurrence of cardiac dysfunction in streptozotocin-induced diabetic rats
Emerging evidence suggests that specific (poly)phenols may constitute new preventative strategies to counteract cell oxidative stress and myocardial tissue inflammation, which have a key role in the patho-phys... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Monia Savi, Leonardo Bocchi, Pedro Mena, Margherita Dall ’Asta, Alan Crozier, Furio Brighenti, Donatella Stilli and Daniele Del Rio Source Type: research

Reduced HDL function in children and young adults with type 1 diabetes
Patients with type 1 diabetes (T1D) are at increased risk of cardiovascular disease (CVD). Measures of high-density lipoprotein (HDL) function provide a better risk estimate for future CVD events than serum le... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Martin Heier, Mark S. Borja, Cathrine Brunborg, Ingebj ørg Seljeflot, Hanna Dis Margeirsdottir, Kristian F. Hanssen, Knut Dahl-Jørgensen and Michael N. Oda Source Type: research

Red blood cell distribution width as a prognostic marker in patients with heart failure and diabetes mellitus
Red blood cell distribution width (RDW) is an established prognostic marker in acute and chronic heart failure (HF). Recent studies have pointed out a link among RDW, diabetes mellitus (DM) and inflammation. W... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Andrew Xanthopoulos, Gregory Giamouzis, Andreas Melidonis, Takeshi Kitai, Efi Paraskevopoulou, Pinelopi Paraskevopoulou, Sotirios Patsilinakos, Filippos Triposkiadis and John Skoularigis Source Type: research

Westernization of lifestyle affects quantitative and qualitative changes in adiponectin
Although Japanese –Americans and native Japanese share the same genetic predispositions, they live different lifestyles, resulting in insulin resistance in Japanese–Americans. We investigated whether the quanti... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2017 Category: Cardiology Authors: Mitsunobu Kubota, Masayasu Yoneda, Norikazu Maeda, Haruya Ohno, Kenji Oki, Tohru Funahashi, Iichiro Shimomura and Noboru Hattori Source Type: research

Sex difference in the risk for exercise-induced albuminuria correlates with hemoglobin A1C and abnormal exercise ECG test findings
Albuminuria is an established marker for endothelial dysfunction and cardiovascular risk in diabetes and prediabetes. Exercise induced albuminuria (EiA) appears earlier and may be a more sensitive biomarker fo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 23, 2017 Category: Cardiology Authors: Rafael Y. Brzezinski, Inbal Etz-Hadar, Ayelet Grupper, Michal Ehrenwald, Itzhak Shapira, David Zeltser, Shlomo Berliner, Ori Rogowski, Roy Eldor and Shani Shenhar-Tsarfaty Source Type: research

Impact of glycemic control on aortic stiffness, left ventricular mass and diastolic longitudinal function in type 2 diabetes mellitus
Poor glycemic control is associated with impaired left ventricular (LV) diastolic function in patients with type 2 diabetes mellitus (T2DM). Inappropriate LV mass increase and accelerated aortic stiffening wer... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 17, 2017 Category: Cardiology Authors: Michaela Kozakova, Carmela Morizzo, Alan G. Fraser and Carlo Palombo Source Type: research

The regulatory role of DPP4 in atherosclerotic disease
The increasing prevalence of atherosclerosis has become a worldwide health concern. Although significant progress has been made in the understanding of atherosclerosis pathogenesis, the underlying mechanisms a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 15, 2017 Category: Cardiology Authors: Lihua Duan, Xiaoquan Rao, Chang Xia, Sanjay Rajagopalan and Jixin Zhong Source Type: research

Elevated serum fibroblast growth factor 23 levels as an indicator of lower extremity atherosclerotic disease in Chinese patients with type 2 diabetes mellitus
Recently, basic and clinical studies have provided evidence supporting the relationship between circulating levels of fibroblast growth factor (FGF) 23 and the development of atherosclerosis. Given that diabet... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 15, 2017 Category: Cardiology Authors: Xingxing He, Xiang Hu, Xiaojing Ma, Hang Su, Lingwen Ying, Jiahui Peng, Xiaoping Pan, Yuqian Bao, Jian Zhou and Weiping Jia Source Type: research

Multipolar pacing by cardiac resynchronization therapy with a defibrillators treatment in type 2 diabetes mellitus failing heart patients: impact on responders rate, and clinical outcomes
Type 2 diabetes mellitus (T2DM) is a multi factorial disease, affecting clinical outcomes in failing heart patients treated by cardiac resynchronization therapy with a defibrillator (CRT-d). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 9, 2017 Category: Cardiology Authors: Celestino Sardu, Michelangela Barbieri, Matteo Santamaria, Valerio Giordano, Cosimo Sacra, Pasquale Paolisso, Alessandro Spirito, Raffaele Marfella, Giuseppe Paolisso and Maria Rosaria Rizzo Source Type: research

Prognostic value of plasma DPP4 activity in ST-elevation myocardial infarction
Dipeptidyl peptidase-4 (DPP4) regulates blood glucose levels and inflammation, and it is also implicated in the pathophysiological process of myocardial infarction (MI). Plasma DPP4 activity (DPP4a) may provid... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Jing-Wei Li, Yun-Dai Chen, Wei-Ren Chen, Qi You, Bo Li, Hao Zhou, Ying Zhang and Tian-Wen Han Source Type: research

The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes
In Phase 2/3 studies of basal insulin peglispro (BIL) compared to insulin glargine, patients with type 1 or type 2 diabetes previously treated with insulin and randomized to BIL had an increase in serum trigly... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Trevor J. Orchard, Bertrand Cariou, Margery A. Connelly, James D. Otvos, Shuyu Zhang, Caryl J. Antalis, Tibor Ivanyi and Byron J. Hoogwerf Source Type: research

Impact of diabetes duration and degree of carotid artery stenosis on major adverse cardiovascular events: a single-center, retrospective, observational cohort study
We aimed to investigate the impact of diabetes duration and carotid artery stenosis (CAS) on the occurrence of major adverse cardiovascular events (MACE) in patients with type 2 diabetes mellitus (T2DM) withou... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 6, 2017 Category: Cardiology Authors: Minsu Noh, Hyunwook Kwon, Chang Hee Jung, Sun U. Kwon, Min Seon Kim, Woo Je Lee, Joong Yeol Park, Youngjin Han, Hyangkyoung Kim, Tae-Won Kwon and Yong-Pil Cho Source Type: research

Platelets, diabetes and myocardial ischemia/reperfusion injury
Mechanisms underlying the pathogenesis of ischemia/reperfusion injury are particularly complex, multifactorial and highly interconnected. A complex and entangled interaction is also emerging between platelet f... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 31, 2017 Category: Cardiology Authors: Isabella Russo, Claudia Penna, Tiziana Musso, Jasmin Popara, Giuseppe Alloatti, Franco Cavalot and Pasquale Pagliaro Source Type: research

Design and rationale of the ODYSSEY DM-DYSLIPIDEMIA trial: lipid-lowering efficacy and safety of alirocumab in individuals with type 2 diabetes and mixed dyslipidaemia at high cardiovascular risk
Type 2 diabetes mellitus (T2DM) is often associated with mixed dyslipidaemia, where non-high-density lipoprotein cholesterol (non-HDL-C) levels may more closely align with cardiovascular risk than low-density ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 25, 2017 Category: Cardiology Authors: Dirk M üller-Wieland, Lawrence A. Leiter, Bertrand Cariou, Alexia Letierce, Helen M. Colhoun, Stefano Del Prato, Robert R. Henry, Francisco J. Tinahones, Lisa Aurand, Jaman Maroni, Kausik K. Ray and Maja Bujas-Bobanovic Source Type: research

The addition of vildagliptin to metformin prevents the elevation of interleukin 1 ß in patients with type 2 diabetes and coronary artery disease: a prospective, randomized, open-label study
Patients with type 2 diabetes present with an accelerated atherosclerotic process. Animal evidence indicates that dipeptidyl peptidase-4 inhibitors (gliptins) have anti-inflammatory and anti-atherosclerotic ef... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 22, 2017 Category: Cardiology Authors: Arwa Younis, Dana Eskenazi, Ronen Goldkorn, Jonathan Leor, Nili Naftali-Shani, Enrique Z. Fisman, Alexander Tenenbaum, Ilan Goldenberg and Robert Klempfner Source Type: research