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Erratum to: National trends in incidence and outcomes of abdominal aortic aneurysm among elderly type 2 diabetic and non-diabetic patients in Spain (2003 –2012)
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 21, 2016 Category: Cardiology Authors: Ana Lopez-de-Andr és, Isabel Jiménez-Trujillo, Rodrigo Jiménez-García, Valentín Hernández-Barrera, José Mª de Miguel-Yanes, Manuel Méndez-Bailón, Napoleón Perez-Farinos, Miguel Ángel Salinero-Fort and Pilar Carrasco-Garrido Source Type: research

Rationale and design of the randomised controlled trial to assess the impact of liraglutide on cardiac function and structure in young adults with type 2 diabetes (the LYDIA study)
The prevalence of type 2 diabetes (T2DM) in younger adults is growing. Compared to the late onset T2DM, it is well recognized that the disease tends to behave more aggressively in the younger age group with ev... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 21, 2016 Category: Cardiology Authors: Z. Z. Htike, T. Yates, E. M. Brady, D. Webb, L. J. Gray, D. Swarbrick, G. P. McCann, K. Khunti and M. J. Davies Source Type: research

Glucagon-like peptide-1 derived cardioprotection does not utilize a KATP-channel dependent pathway: mechanistic insights from human supply and demand ischemia studies
Glucagon-like peptide-1 (7–36) amide (GLP-1) protects against stunning and cumulative left ventricular dysfunction in humans. The mechanism remains uncertain but GLP-1 may act by opening mitochondrial K-ATP ch... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2016 Category: Cardiology Authors: Joel P. Giblett, Richard G. Axell, Paul A. White, Sophie J. Clarke, Liam McCormick, Philip A. Read, Johannes Reinhold, Adam J. Brown, Michael O’Sullivan, Nick E. J. West, David P. Dutka and Stephen P. Hoole Source Type: research

The relationship between HbA1c and ultrasound plaque textures in atherosclerotic patients
Diabetes mellitus (DM) is associated to the morphological and componential characteristics of atheromatous plaques. It has proven that plaque textures are related to plaque components and beneficial for athero... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2016 Category: Cardiology Authors: Xiao-Wei Huang, Yan-Ling Zhang, Long Meng, Ming Qian, Wei Zhou, Rong-Qin Zheng, Hai-Rong Zheng and Li–Li Niu Source Type: research

Clinical outcomes of deferred revascularisation using fractional flow reserve in patients with and without diabetes mellitus
Deferred revascularisation based upon fractional flow reserve (FFR >0.80) is associated with a low incidence of target lesion failure (TLF). Whether deferred revascularisation is also as safe in diabetes melli... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2016 Category: Cardiology Authors: Mark W. Kennedy, Eliza Kaplan, Rik S. Hermanides, Enrico Fabris, Veemal Hemradj, Petra C. Koopmans, Jan-Hank E. Dambrink, A. T. Marcel Gosselink, Arnoud W. J. van‘t Hof, Jan Paul Ottervanger, Vincent Roolvink, Wouter S. Remkes, Aize van der Sluis, Harry Source Type: research

The influence of baseline risk on the relation between HbA1c and risk for new cardiovascular events and mortality in patients with type 2 diabetes and symptomatic cardiovascular disease
Strict glycaemic control in patients with type 2 diabetes has proven to have microvascular benefits while the effects on CVD and mortality are less clear, especially in high risk patients. Whether strict glyca... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 19, 2016 Category: Cardiology Authors: Sophie H. Bots, Yolanda van der Graaf, Hendrik M. W. Nathoe, Gert Jan de Borst, Jaap L. Kappelle, Frank L. J. Visseren and Jan Westerink Source Type: research

Research into the effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design
Heart failure (HF) and diabetes (DM) are a lethal combination. The current armamentarium of anti-diabetic agents has been shown to be less efficacious and sometimes even harmful in diabetic patients with conco... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 15, 2016 Category: Cardiology Authors: Jagdeep S. S. Singh, Amir Fathi, Keeran Vickneson, Ify Mordi, Mohapradeep Mohan, J. Graeme Houston, Ewan R. Pearson, Allan D. Struthers and Chim C. Lang Source Type: research

Effect of the long-acting insulin analogues glargine and degludec on cardiomyocyte cell signalling and function
The effects of insulin on cardiomyocytes, such as positive inotropic action and glucose uptake are well described. However, in vitro studies comparing long-acting insulin analogues with regard to cardiomyocyte... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 15, 2016 Category: Cardiology Authors: Thorsten Hartmann, Sabrina Overhagen, D. Margriet Ouwens, Silja Raschke, Paulus Wohlfart, Norbert Tennagels, Nina Wronkowitz and Jürgen Eckel Source Type: research

Common medications used by patients with type 2 diabetes mellitus: what are their effects on the lipid profile?
Dyslipidemia is the most fundamental risk factor for atherosclerotic cardiovascular disease (ASCVD). In clinical practice, many commonly prescribed medications can alter the patient’s lipid profile and, potent... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 14, 2016 Category: Cardiology Authors: Paul D. Rosenblit Source Type: research

Dipeptidyl peptidase-4 inhibition with linagliptin prevents western diet-induced vascular abnormalities in female mice
Vascular stiffening, a risk factor for cardiovascular disease, is accelerated, particularly in women with obesity and type 2 diabetes. Preclinical evidence suggests that dipeptidylpeptidase-4 (DPP-4) inhibitor... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 8, 2016 Category: Cardiology Authors: Camila Manrique, Javad Habibi, Annayya R. Aroor, James R. Sowers, Guanghong Jia, Melvin R. Hayden, Mona Garro, Luis A. Martinez-Lemus, Francisco I. Ramirez-Perez, Thomas Klein, Gerald A. Meininger and Vincent G. DeMarco Source Type: research

Effect of obesity on the effectiveness of cardiac resynchronization to reduce the risk of first and recurrent ventricular tachyarrhythmia events
Obesity is associated with multiple adverse cardiovascular conditions and may increase the risk of ventricular tachyarrhythmias (VT/VF). There is limited data on the association between obesity and risk of VT/... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 7, 2016 Category: Cardiology Authors: Barbara Szepietowska, Bronislava Polonsky, Saadia Sherazi, Yitschak Biton, Valentina Kutyifa, Scott McNitt, Mehmet Aktas, Arthur J. Moss and Wojciech Zareba Source Type: research

Alterations in heart rate variability during everyday life are linked to insulin resistance. A role of dominating sympathetic over parasympathetic nerve activity?
To evaluate the role of the autonomic nervous system (ANS) in the development of insulin resistance (IR) and assess the relationship between IR and activity of ANS using power spectrum analysis of heart rate v... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 28, 2016 Category: Cardiology Authors: Maria K. Svensson, Stina Lindmark, Urban Wiklund, Peter Rask, Marcus Karlsson, Jan Myrin, Joel Kullberg, Lars Johansson and Jan W. Eriksson Source Type: research

Impact of metabolic syndrome on the progression of coronary calcium and of coronary artery disease assessed by repeated cardiac computed tomography scans
It is not clear how severe metabolic syndrome (MS) affects the development of coronary atherosclerosis. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 28, 2016 Category: Cardiology Authors: Lee Kyung Kim, Ji Won Yoon, Dong-Hwa Lee, Kyoung Min Kim, Sung Hee Choi, Kyong Soo Park, Hak Chul Jang, Min-Kyung Kim, Hyo Eun Park, Su-Yeon Choi and Soo Lim Source Type: research

Association between omentin-1 expression in human epicardial adipose tissue and coronary atherosclerosis
Omentin-1, a novel adipocytokine mainly expressed in visceral adipose tissue, has been found to inhibit the inflammatory response and improve insulin resistance as well as other obesity-related disorders. This... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 28, 2016 Category: Cardiology Authors: Yu Du, Qingwei Ji, Lun Cai, Fangjiong Huang, Yongqiang Lai, Yue Liu, Jianbo Yu, Bo Han, Enjun Zhu, Jinwei Zhang, Yujie Zhou, Zhijian Wang and Yingxin Zhao Source Type: research

Efficacy and safety of canagliflozin in combination with insulin: a double-blind, randomized, placebo-controlled study in Japanese patients with type 2 diabetes mellitus
Combination therapy with canagliflozin and insulin was investigated in a prescribed substudy of the canagliflozin Cardiovascular Assessment Study (CANVAS); however, it was not evaluated in Japanese patients wi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 18, 2016 Category: Cardiology Authors: Nobuya Inagaki, Shin-ichi Harashima, Nobuko Maruyama, Yutaka Kawaguchi, Maki Goda and Hiroaki Iijima Source Type: research

Rationale and design of a multicenter randomized study for evaluating vascular function under uric acid control using the xanthine oxidase inhibitor, febuxostat: the PRIZE study
Xanthine oxidase inhibitors are anti-hyperuricemic drugs that decrease serum uric acid levels by inhibiting its synthesis. Xanthine oxidase is also recognized as a pivotal enzyme in the production of oxidative... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 18, 2016 Category: Cardiology Authors: Jun-ichi Oyama, Atsushi Tanaka, Yasunori Sato, Hirofumi Tomiyama, Masataka Sata, Tomoko Ishizu, Isao Taguchi, Takanori Kuroyanagi, Hiroki Teragawa, Nobukazu Ishizaka, Yumiko Kanzaki, Mitsuru Ohishi, Kazuo Eguchi, Yukihito Higashi, Hirotsugu Yamada, Koji M Source Type: research

Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice
Endothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) i... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 18, 2016 Category: Cardiology Authors: Jia-Wen Yu, Ya-Ping Deng, Xue Han, Guo-Fei Ren, Jian Cai and Guo-Jun Jiang Source Type: research

Beyond type 2 diabetes, obesity and hypertension: an axis including sleep apnea, left ventricular hypertrophy, endothelial dysfunction, and aortic stiffness among Mexican Americans in Starr County, Texas
There is an increasing appreciation for a series of less traditional risk factors that should not be ignored when considering type 2 diabetes, obesity, hypertension, and cardiovascular disease. These include a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 8, 2016 Category: Cardiology Authors: Craig L. Hanis, Susan Redline, Brian E. Cade, Graeme I. Bell, Nancy J. Cox, Jennifer E. Below, Eric L. Brown and David Aguilar Source Type: research

The EMPA-REG outcome study: critical appraisal and potential clinical implications
Diabetes health care professionals have to face a study with results of incomparable success in secondary and tertiary cardiovascular disease prevention. In the past, no studies in patients with type 2 diabete... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 4, 2016 Category: Cardiology Authors: Gianluca Perseghin and Anna Solini Source Type: research

The nine-year changes of the incidence and characteristics of metabolic syndrome in China: longitudinal comparisons of the two cross-sectional surveys in a newly formed urban community
To assess the 9-year changes of the incidence and characteristics of metabolic syndrome (MetS) in Chinese community under the background of dramatically changed environment. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 3, 2016 Category: Cardiology Authors: Boren Jiang, Bin Li, Yongbin Wang, Bing Han, Ningjian Wang, Qin Li, Weihong Yang, Guolan Huang, Jinhua Wang, Yi Chen, Yingchao Chen, Chunfang Zhu, Dongping Lin and Yingli Lu Source Type: research

Diastolic orthostatic hypertension and cardiovascular prognosis in type 2 diabetes: a prospective cohort study
In patients with type 2 diabetes, the prognostic impact of an orthostatic rise in blood pressure is not known. Therefore, the aim of this study was to determine the prognostic implications of the diastolic ort... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 2, 2016 Category: Cardiology Authors: Magnus Wijkman, Toste Länne, Carl Johan Östgren and Fredrik H. Nystrom Source Type: research

Inflammation, glucose, and vascular cell damage: the role of the pentose phosphate pathway
Hyperglycemia is acknowledged as a pro-inflammatory condition and a major cause of vascular damage. Nevertheless, we have previously described that high glucose only promotes inflammation in human vascular cel... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 1, 2016 Category: Cardiology Authors: Concepción Peiró, Tania Romacho, Verónica Azcutia, Laura Villalobos, Emilio Fernández, Juan P. Bolaños, Salvador Moncada and Carlos F. Sánchez-Ferrer Source Type: research

Statin use and cardiovascular risk factors in diabetic patients developing a first myocardial infarction
The risk for a first myocardial infarction (MI) in people with diabetes has been shown to be as high as the risk for a new MI in non-diabetic patients with a prior MI. Consequently, risk-reducing statin therap... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 27, 2016 Category: Cardiology Authors: Martin Bødtker Mortensen, Imra Kulenovic and Erling Falk Source Type: research

Palaeolithic diet decreases fasting plasma leptin concentrations more than a diabetes diet in patients with type 2 diabetes: a randomised cross-over trial
We have previously shown that a Palaeolithic diet consisting of the typical food groups that our ancestors ate during the Palaeolithic era, improves cardiovascular disease risk factors and glucose control comp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 23, 2016 Category: Cardiology Authors: Maelán Fontes-Villalba, Staffan Lindeberg, Yvonne Granfeldt, Filip K. Knop, Ashfaque A. Memon, Pedro Carrera-Bastos, Óscar Picazo, Madhvi Chanrai, Jan Sunquist, Kristina Sundquist and Tommy Jönsson Source Type: research

Effects of daily glucose fluctuations on the healing response to everolimus-eluting stent implantation as assessed using continuous glucose monitoring and optical coherence tomography
Several studies have revealed that glucose fluctuations provoke oxidative stress that leads to endothelial cell dysfunction, progression of coronary atherosclerosis, and plaque vulnerability. However, little i... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 21, 2016 Category: Cardiology Authors: Masaru Kuroda, Toshiro Shinke, Hiromasa Otake, Daisuke Sugiyama, Tomofumi Takaya, Hachidai Takahashi, Daisuke Terashita, Kenzo Uzu, Natsuko Tahara, Daiji Kashiwagi, Koji Kuroda, Yuto Shinkura, Yoshinori Nagasawa, Kazuhiko Sakaguchi, Yushi Hirota, Wataru O Source Type: research

Impact of individual metabolic risk components or its clustering on endothelial and smooth muscle cell function in men
Impaired vasoreactivity is often observed in subjects with metabolic syndrome, a condition that includes the presence of a specific cluster of risk factors for obesity and cardiovascular disease. However, hier... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 17, 2016 Category: Cardiology Authors: Michio Shimabukuro, Namio Higa, Hiroaki Masuzaki, Masataka Sata and Shinichiro Ueda Source Type: research

Major adverse cardiovascular events with basal insulin peglispro versus comparator insulins in patients with type 1 or type 2 diabetes: a meta-analysis
To identify possible differences in cardiovascular (CV) risk among different insulin therapies, we performed pre-specified meta-analyses across the clinical program for basal insulin peglispro (BIL), in patien... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 17, 2016 Category: Cardiology Authors: Byron J. Hoogwerf, A. Michael Lincoff, Angel Rodriguez, Lei Chen and Yongming Qu Source Type: research

Impact of teneligliptin on oxidative stress and endothelial function in type 2 diabetes patients with chronic kidney disease: a case–control study
The aim of the present study was to elucidate the effect of teneligliptin on oxidative stress and endothelial function in Japanese patients with type 2 diabetes and chronic kidney disease (CKD). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 17, 2016 Category: Cardiology Authors: Masaaki Sagara, Kunihiro Suzuki, Chie Aoki, Seiichi Tanaka, Isao Taguchi, Teruo Inoue and Yoshimasa Aso Source Type: research

Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway
Type-2 diabetics have an increased risk of cardiomyopathy, and heart failure is a major cause of death among these patients. Growing evidence indicates that proinflammatory cytokines may induce the development... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 6, 2016 Category: Cardiology Authors: Sevil Korkmaz-Icöz, Samer Al Said, Tamás Radovits, Shiliang Li, Maik Brune, Péter Hegedűs, Ayhan Atmanli, Mihály Ruppert, Paige Brlecic, Lorenz Heyne Lehmann, Bernd Lahrmann, Niels Grabe, Yutaka Yoshikawa, Hiroyuki Yasui, Patrick Most and Matthias Ka Source Type: research

The prevalence of diabetes, hypertension and obesity among immigrants from East Africa and the former Soviet Union: a retrospective comparative 30-year cohort study
Previous studies have reported an increasing prevalence of metabolic abnormalities in immigrants who moved from low-cardiovascular-risk regions to Western countries, but little is known about time trends follo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 5, 2016 Category: Cardiology Authors: Yonatan Reuven, Jacob Dreiher and Pesach Shvartzman Source Type: research

Achievement of treatment goals for secondary prevention of myocardial infarction or stroke in 29,325 patients with type 2 diabetes: a German/Austrian DPV-multicenter analysis
To analyze whether medical care is in accordance with guidelines for secondary prevention of myocardial infarction (MI), or stroke in patients with type 2 diabetes from Germany and Austria. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 3, 2016 Category: Cardiology Authors: Barbara Bohn, Christof Schöfl, Vincent Zimmer, Michael Hummel, Nikolai Heise, Erhard Siegel, Wolfram Karges, Michaela Riedl and Reinhard W. Holl Source Type: research

Low birth weight leads to obesity, diabetes and increased leptin levels in adults: the CoLaus study
Low birth weight is associated with increased rates of obesity, insulin resistance and type 2 diabetes, but the precise mechanisms for this association remain unclear. We aimed to assess the relationships betw... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 3, 2016 Category: Cardiology Authors: François R. Jornayvaz, Peter Vollenweider, Murielle Bochud, Vincent Mooser, Gérard Waeber and Pedro Marques-Vidal Source Type: research

Oscillating glucose induces microRNA-185 and impairs an efficient antioxidant response in human endothelial cells
Intracellular antioxidant response to high glucose is mediated by Cu/Mn-superoxide dismutases (SOD-1/SOD-2), catalase (CAT) and glutathione peroxidases (GPx), particularly glutathione peroxidase-1 (GPx-1). Alt... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 30, 2016 Category: Cardiology Authors: Lucia La Sala, Monica Cattaneo, Valeria De Nigris, Gemma Pujadas, Roberto Testa, Anna R. Bonfigli, Stefano Genovese and Antonio Ceriello Source Type: research

The source of circulating selenoprotein S and its association with type 2 diabetes mellitus and atherosclerosis: a preliminary study
Selenoprotein S (SelS) is a transmembrane protein that is expressed in the liver, skeletal muscle, adipose tissue, pancreatic islets, kidney, and blood vessels. In addition to its transmembrane localization, S... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 28, 2016 Category: Cardiology Authors: Shan-shan Yu, Li–li Men, Jia-ling Wu, Li-wei Huang, Qian Xing, Jun-jie Yao, Yong-bo Wang, Gui-rong Song, Hui-shu Guo, Guo-hua Sun, Yu-hong Zhang, Hua Li and Jian-ling Du Source Type: research

The clinical value of metabolic syndrome and risks of cardiometabolic events and mortality in the elderly: the Rotterdam study
To evaluate the clinical value of metabolic syndrome based on different definitions [American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI), International Diabetes Federation (IDF) and... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 27, 2016 Category: Cardiology Authors: Thijs T. W. van Herpt, Abbas Dehghan, Mandy van Hoek, M. Arfan Ikram, Albert Hofman, Eric J. G. Sijbrands and Oscar H. Franco Source Type: research

Severely impaired microvascular reactivity in diabetic patients with an acute coronary syndrome
Microvascular function is impaired in patients with stable coronary artery disease. The aim was to study microvascular function in patients with diabetes and acute coronary syndrome (ACS). (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 20, 2016 Category: Cardiology Authors: Nikolaos Östlund Papadogeorgos, Gun Jörneskog, Mattias Bengtsson, Thomas Kahan and Majid Kalani Source Type: research

Impaired coronary microcirculation in type 2 diabetic patients is associated with elevated circulating regulatory T cells and reduced number of IL-21R+ T cells
Low-grade systemic inflammation is considered to participate in the progression of type 2 diabetes (T2D) and in diabetic complications. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 19, 2016 Category: Cardiology Authors: Bernt Johan von Scholten, Alexander Rosendahl, Philip Hasbak, Regine Bergholdt, Andreas Kjaer, Peter Rossing and Tine W. Hansen Source Type: research

Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study
Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, the respons... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 19, 2016 Category: Cardiology Authors: A. Leon-Acuña, J. F. Alcala-Diaz, J. Delgado-Lista, J. D. Torres-Peña, J. Lopez-Moreno, A. Camargo, A. Garcia-Rios, C. Marin, F. Gomez-Delgado, J. Caballero, B. Van-Ommen, M. M. Malagon, P. Perez-Martinez and J. Lopez-Miranda Source Type: research

Clinical relevance of dual-energy X-ray absorptiometry (DXA) as a simultaneous evaluation of fatty liver disease and atherosclerosis in patients with type 2 diabetes
Whole body dual-energy X-ray absorptiometry (DXA) can simultaneously measure both regional fat and non-fat mass. Android-to-gynoid (A/G) ratio measured by DXA has been reported to be associated with cardiovasc... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 14, 2016 Category: Cardiology Authors: Ryotaro Bouchi, Yujiro Nakano, Norihiko Ohara, Takato Takeuchi, Masanori Murakami, Masahiro Asakawa, Yuriko Sasahara, Mitsuyuki Numasawa, Isao Minami, Hajime Izumiyama, Koshi Hashimoto, Takanobu Yoshimoto and Yoshihiro Ogawa Source Type: research

Metabolically-inactive glucagon-like peptide-1(9–36)amide confers selective protective actions against post-myocardial infarction remodelling
Glucagon-like peptide-1 (GLP-1) therapies are routinely used for glycaemic control in diabetes and their emerging cardiovascular actions have been a major recent research focus. In addition to GLP-1 receptor a... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 14, 2016 Category: Cardiology Authors: Emma Robinson, Mitchel Tate, Samuel Lockhart, Claire McPeake, Karla M. O’Neill, Kevin S. Edgar, Danielle Calderwood, Brian D. Green, Barbara J. McDermott and David J. Grieve Source Type: research

Berberine alleviates the cerebrovascular contractility in streptozotocin-induced diabetic rats through modulation of intracellular Ca2+ handling in smooth muscle cells
Vascular dysfunction is a distinctive phenotype in diabetes mellitus. Current treatments mostly focus on the tight glycemic control and few of these treatments have been designed to directly recover the vascul... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 12, 2016 Category: Cardiology Authors: Yu-Guang Ma, Yin-Bin Zhang, Yun-Gang Bai, Zhi-Jun Dai, Liang Liang, Mei Liu, Man-Jiang Xie and Hai-Tao Guan Source Type: research

Nicorandil attenuates carotid intimal hyperplasia after balloon catheter injury in diabetic rats
Diabetic patients suffer from undesired intimal hyperplasia after angioplasty. Nicorandil has a trend to reduce the rate of target lesion revascularization. However, whether nicorandil inhibits intimal hyperpl... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 8, 2016 Category: Cardiology Authors: Ying Qian Zhang, Feng Tian, Ying Zhou, Yun Dai Chen, Bo Li, Qiang Ma and Ying Zhang Source Type: research

Determinants of growth differentiation factor 15 in patients with stable and acute coronary artery disease. A prospective observational study
Growth differentiation factor 15 (GDF-15) is a member of the transforming growth factor ß family and has been associated with inflammation, cancer, aging, diabetes mellitus (DM) and atherosclerosis. Determinan... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 8, 2016 Category: Cardiology Authors: Serdar Farhan, Matthias K. Freynhofer, Ivan Brozovic, Veronika Bruno, Birgit Vogel, Ioannis Tentzeris, Sabina Baumgartner-Parzer, Kurt Huber and Alexandra Kautzky-Willer Source Type: research

Cohort profile: the German Diabetes Study (GDS)
The German Diabetes Study (GDS) is a prospective longitudinal cohort study describing the impact of subphenotypes on the course of the disease. GDS aims at identifying prognostic factors and mechanisms underly... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 7, 2016 Category: Cardiology Authors: Julia Szendroedi, Aaruni Saxena, Katharina S. Weber, Klaus Strassburger, Christian Herder, Volker Burkart, Bettina Nowotny, Andrea Icks, Oliver Kuss, Dan Ziegler, Hadi Al-Hasani, Karsten Müssig and Michael Roden Source Type: research

The influence of body composition on the N-terminal pro-B-type natriuretic peptide level and its prognostic performance in patients with acute coronary syndrome: a cohort study
Whether body composition is associated with the N-terminal pro-B-type natriuretic peptide (NT-proBNP) level and its prognostic performance in acute coronary syndrome (ACS) remains unknown. We aimed to investig... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 6, 2016 Category: Cardiology Authors: Fang-Yang Huang, Hua Wang, Bao-Tao Huang, Wei Liu, Yong Peng, Chen Zhang, Tian-Li Xia, Peng-Ju Wang, Zhi-Liang Zuo, Yue Heng, Rui-Shuang Liu, Xiao-Bo Pu, Yi-Yue Gui, Shi-Jian Chen, Ye Zhu and Mao Chen Source Type: research

Association between socioeconomic status and metabolic control and diabetes complications: a cross-sectional nationwide study in Chinese adults with type 2 diabetes mellitus
Low socioeconomic status (SES) is associated with adverse cardiovascular risk factor patterns and poor outcomes in patients with diabetes. The aim of this study was to determine whether SES is associated with ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 5, 2016 Category: Cardiology Authors: Xiaoming Tao, Jihu Li, Xiaolin Zhu, Bin Zhao, Jiao Sun, Linong Ji, Dayi Hu, Changyu Pan, Yuxin Huang, Suyuan Jiang, Qiang Feng and Cuiping Jiang Source Type: research

Rationale and design of a randomized trial to test the safety and non-inferiority of canagliflozin in patients with diabetes with chronic heart failure: the CANDLE trial
Because type 2 diabetes mellitus is associated strongly with an increased risk of cardiovascular diseases, the number of patients with diabetes with chronic heart failure is increasing steadily. However, clini... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 4, 2016 Category: Cardiology Authors: Atsushi Tanaka, Teruo Inoue, Masafumi Kitakaze, Jun-ichi Oyama, Masataka Sata, Isao Taguchi, Wataru Shimizu, Hirotaka Watada, Hirofumi Tomiyama, Junya Ako, Yasushi Sakata, Toshihisa Anzai, Masaaki Uematsu, Makoto Suzuki, Kazuo Eguchi, Akira Yamashina&hell Source Type: research

A comparison between angiotensin converting enzyme inhibitors and angiotensin receptor blockers on end stage renal disease and major adverse cardiovascular events in diabetic patients: a population-based dynamic cohort study in Taiwan
Contemporary guidelines recommend angiotensin-converting-enzyme inhibitors (ACEi) or angiotensin-receptor blockers (ARB) for hypertensive patients with diabetes. However, there is limited data to evaluate the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2016 Category: Cardiology Authors: Lung-Sheng Wu, Shang-Hung Chang, Gwo-Jyh Chang, Jia-Rou Liu, Yi-Hsin Chan, Hsin-Fu Lee, Ming-Shien Wen, Wei-Jan Chen, Yung-Hsin Yeh, Chi-Tai Kuo and Lai-Chu See Source Type: research

Need for streamlined use of DPP-4 inhibitors in the treatment of type 2 diabetes
Regulatory agencies request an assessment of cardiovascular safety for all “new” oral anti-diabetic drugs in order to avoid possible negative effects on cardiovascular events. Dipeptidyl peptidase 4 inhibitors... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - April 2, 2016 Category: Cardiology Authors: Cristiana Vitale, Giuseppe M. C. Rosano and Krishna Prasad Source Type: research

Cardiovascular efficacy of sitagliptin in patients with diabetes at high risk of cardiovascular disease: a 12-month follow-up
Gliptins should have beneficial effects beyond glycemic control, potentially on the pathophysiology of cardiovascular (CV) diseases, with some basic studies demonstrating this possibility. However, we are yet ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - March 31, 2016 Category: Cardiology Authors: Takashi Nakamura, Yoshitaka Iwanaga, Yuki Miyaji, Ryuji Nohara, Takao Ishimura and Shunichi Miyazaki Source Type: research