Glycemic control and cardiovascular outcomes in patients with diabetes and coronary artery disease according to triglyceride-glucose index: a large-scale cohort study
The role of triglyceride-glucose (TyG) index, an insulin resistance indicator, in glycemic management for diabetic patients with coronary artery disease (CAD) was still unknown. Therefore, we aimed to explore ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Zhangyu Lin, Jining He, Sheng Yuan, Chenxi Song, Xiaohui Bian, Min Yang and Kefei Dou Tags: Research Source Type: research

Nonlinear relationship between untraditional lipid parameters and the risk of prediabetes: a large retrospective study based on Chinese adults
Abnormal lipid metabolism poses a risk for prediabetes. However, research on lipid parameters used to predict the risk of prediabetes is scarce, and the significance of traditional and untraditional lipid para... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Mingkang Li, Wenkang Zhang, Minhao Zhang, Linqing Li, Dong Wang, Gaoliang Yan, Yong Qiao and Chengchun Tang Tags: Research Source Type: research

Triglyceride-glucose index as a suitable non-insulin-based insulin resistance marker to predict cardiovascular events in patients undergoing complex coronary artery intervention: a large-scale cohort study
Insulin resistance (IR), a hallmark of proceeding diabetes and cardiovascular (CV) disease, has been shown to predict prognosis in patients undergoing percutaneous coronary intervention (PCI). The triglyceride... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Jining He, Chenxi Song, Sheng Yuan, Xiaohui Bian, Zhangyu Lin, Min Yang and Kefei Dou Tags: Research Source Type: research

Association between the cumulative average triglyceride glucose-body mass index and cardiovascular disease incidence among the middle-aged and older population: a prospective nationwide cohort study in China
Findings from earlier research have established that insulin resistance (IR) is implicated in atherosclerosis progression, representing a noteworthy risk factor for cardiovascular disease (CVD). Recently, the ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 6, 2024 Category: Cardiology Authors: Fadong Li, Yue Wang, Boqun Shi, Shuaifeng Sun, Shen Wang, Shuo Pang and Xiaofan Wu Tags: Research Source Type: research

Semaglutide modulates prothrombotic and atherosclerotic mechanisms, associated with epicardial fat, neutrophils and endothelial cells network
Obesity has increased in recent years with consequences on diabetes and other comorbidities. Thus, 1 out of 3 diabetic patients suffers cardiovascular disease (CVD). The network among glucose, immune system, e... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: David Garc ía-Vega, David Sánchez-López, Gemma Rodríguez-Carnero, Rocío Villar-Taibo, Juan E. Viñuela, Adán Lestegás-Soto, Ana Seoane-Blanco, María Moure-González, Susana B. Bravo, Ángel L. Fernández, José R. González-Juanatey and Sonia Eira Tags: Research Source Type: research

Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population
The triglyceride-glucose (TyG) index has been proposed as a surrogate marker of insulin resistance. However, the relationship between the TyG index and central blood pressure (BP), has not been well studied in... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Yin-Hua Sun, Nai-Qing Hu, Xian-Yi Huang, Zheng-Xin Liu, Qi-Yan Li, Qing-Lu Li and Li-Hua Li Tags: Research Source Type: research

Impact of PCSK9 inhibitors in glycaemic control and new-onset diabetes
The diabetogenic effect of statins has been well established by clinical trials, Mendelian randomisation studies and meta-analyses. According to large clinical trials, PCSK9 inhibitors (PCSK9i) have no deleter... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Ana M. Gonz ález-Lleó, Rosa M. Sánchez-Hernández, Núria Plana, Daiana Ibarretxe, Pere Rehues, Josep Ribalta, Dídac Llop, Ana M. Wägner, Lluís Masana and Mauro Boronat Tags: Research Source Type: research

Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population
The triglyceride-glucose (TyG) index is regarded as a sophisticated surrogate biomarker for insulin resistance, offering a refined means for evaluating cardiovascular diseases (CVDs). However, prospective coho... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Yue Wang, Xueyu Chen, Jie Shi, Mingyi Du, Shengnan Li, Jinhong Pang, Junpeng Qiao, Yingying Zhao, Qiaoqiao Chen, Yuanyuan Guo, Yan Xi and Weiwei Chi Tags: Research Source Type: research

Association of long-term triglyceride-glucose index patterns with the incidence of chronic kidney disease among non-diabetic population: evidence from a functional community cohort
The triglyceride-glucose (TyG) index is a reliable surrogate marker of insulin resistance and previous studies have confirmed the association of TyG index with incident chronic kidney disease (CKD). However, t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 3, 2024 Category: Cardiology Authors: Ning Chen, Lin-Lin Ma, Yu Zhang, Xi Chu, Jing Dong and Yu-Xiang Yan Tags: Research Source Type: research

Long-term effects of blood pressure 130 –139/80–89 mmHg on all-cause and cardiovascular mortality among Chinese adults with different glucose metabolism
This study aimed to investigate the risks of all-cause and cardiovascular mortality associated with blood pressure (BP) levels of 130 –139/80–89 mmHg in Chinese adults with different glucose metabolism, during ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 21, 2023 Category: Cardiology Authors: Chang-Sheng Sheng, Haiyan Wang, Yanjun Liu, Yanyun Li, TianZhiChao Hou, Miaoyan Qiu, Yao Lu, Siming Sun, Junhan Yang, Xiaomin Song, Guang Ning and Jingyan Tian Tags: Research Source Type: research

Combined effect of adiposity and elevated inflammation on incident type 2 diabetes: a prospective cohort study
Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Dan Wu, Yulong Lan, Shuohua Chen, Xiong Ding, Guanzhi Chen, Chutao Wu, Lois Balmer, Wencan Xu, Shouling Wu and Wei Wang Tags: Research Source Type: research

Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study
Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng and Shumin Yang Tags: Research Source Type: research

Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and epicardial glucose uptake in human type 2 diabetes
We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients with type 2 diabetes (T2D) with stable coronary arte... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Francesca Cinti, Lucia Leccisotti, Gian Pio Sorice, Umberto Capece, Domenico D ’Amario, Margherita Lorusso, Shawn Gugliandolo, Cassandra Morciano, Andrea Guarneri, Maria Angela Guzzardi, Teresa Mezza, Amedeo Capotosti, Luca Indovina, Pietro Manuel Ferra Tags: Research Source Type: research

Early insulin resistance in normoglycemic low-risk individuals is associated with subclinical atherosclerosis
Elevated glycated hemoglobin (HbA1c) is associated with a higher burden of subclinical atherosclerosis (SA). However, the association with SA of earlier insulin resistance markers is poorly understood. The stu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Josep Iglesies-Grau, Ana Garcia-Alvarez, Bel én Oliva, Guiomar Mendieta, Inés García-Lunar, José J. Fuster, Ana Devesa, Cristina Pérez-Herreras, Antonio Fernández-Ortiz, Ramon Brugada, Borja Ibanez, Rodrigo Fernandez-Jimenez and Valentin Fuster Tags: Research Source Type: research

Prediabetes increases the risk of major limb and cardiovascular events
Prediabetes, an intermediate stage between normal blood sugar levels and a diabetes mellitus diagnosis, is increasing in prevalence. Severe prediabetes is associated with a similar risk of complications as dia... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Jung-Chi Hsu, Yen-Yun Yang, Shu-Lin Chuang, Jen-Kuang Lee and Lian-Yu Lin Tags: Research Source Type: research