PDM-ProValue meets cardiovascular outcome trials in diabetes
Novel studies have increased our knowledge regarding optimal treatment options in diabetes. Key studies that have broadened our knowledge about optimal treatment options in diabetes in recent years are cardiov... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 28, 2019 Category: Cardiology Authors: Katharina Fritzen and Oliver Schnell Tags: Commentary Source Type: research

Concerns about clinical efficacy and safety of warfarin in diabetic patients with atrial fibrillation
Atrial fibrillation (AF) is one of the most common arrhythmias in elderly people. The risk of thromboembolic stroke is increased in AF patients, especially those with diabetes. Anticoagulant therapy, such as w... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 28, 2019 Category: Cardiology Authors: Sho-ichi Yamagishi Tags: Commentary Source Type: research

Remnant lipoproteins play an important role of in-stent restenosis in type 2 diabetes undergoing percutaneous coronary intervention: a single-centre observational cohort study
Increasing evidence has suggested that the presence of remnant lipoproteins is a significant risk factor for atherosclerosis. Remnant lipoproteins are lipoproteins that are rich in triglycerides (TGs), and the... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 28, 2019 Category: Cardiology Authors: Zheng Qin, Kuo Zhou, Yue-ping Li, Jian-long Wang, Wan-jun Cheng, Cheng-ping Hu, Chao Shi, Hua He and Yu-jie Zhou Tags: Original investigation Source Type: research

Developmental trajectories of body mass index from childhood into late adolescence and subsequent late adolescence –young adulthood cardiometabolic risk markers
Reports on body mass index (BMI) trajectories from childhood into late adolescence, their determinants, and subsequent cardiometabolic risk markers, particularly among European populations have been few. Moreo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 19, 2019 Category: Cardiology Authors: Kolade Oluwagbemigun, Anette E. Buyken, Ute Alexy, Matthias Schmid, Christian Herder and Ute N öthlings Tags: Original investigation Source Type: research

Sortilin levels are associated with peripheral arterial disease in type 2 diabetic subjects
Sortilin is a 95-kDa protein which has recently been linked to circulating cholesterol concentration and lifetime risk of developing significant atherosclerotic disease. Sortilin is found inside different cell... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2019 Category: Cardiology Authors: Federico Biscetti, Nicola Bonadia, Francesco Santini, Flavia Angelini, Elisabetta Nardella, Dario Pitocco, Angelo Santoliquido, Marco Filipponi, Raffaele Landolfi and Andrea Flex Tags: Original investigation Source Type: research

Reduction in the incidence of myocardial infarction with sodium –glucose linked cotransporter-2 inhibitors: evident and plausible
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2019 Category: Cardiology Authors: Richard E. Gilbert and Kim A. Connelly Tags: Commentary Source Type: research

Association between serum haptoglobin and carotid arterial functions: usefulness of a targeted metabolomics approach
Serum haptoglobin (Hp) has been closely associated with cardio-cerebrovascular diseases. We investigated a metabolic profile associated with circulating Hp and carotid arterial functions via a targeted metabol... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2019 Category: Cardiology Authors: Shiyun Wang, Jie Wang, Rong Zhang, Aihua Zhao, Xiaojiao Zheng, Dandan Yan, Feng Jiang, Wei Jia, Cheng Hu and Weiping Jia Tags: Original investigation Source Type: research

Improved outcome of patients with diabetes mellitus with good glycemic control in the cardiac intensive care unit: a retrospective study
Diabetes mellitus (DM) is a prevalent metabolic disease characterized by chronic hyperglycemia. A primary burden of DM is related to its long-term complications, which have been shown to impact the course of h... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2019 Category: Cardiology Authors: Kassem Sharif, Suheil Ghadir, Daniela Jakubowicz, Howard Amital, Nicola Luigi Bragazzi, Abdulla Watad, Julio Wainstein and Yosefa Bar-Dayan Tags: Original investigation Source Type: research

MiR-30c/PGC-1 β protects against diabetic cardiomyopathy via PPARα
Metabolic abnormalities have been implicated as a causal event in diabetic cardiomyopathy (DCM). However, the mechanisms underlying cardiac metabolic disorder in DCM were not fully understood. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 11, 2019 Category: Cardiology Authors: Zhongwei Yin, Yanru Zhao, Mengying He, Huaping Li, Jiahui Fan, Xiang Nie, Mengwen Yan, Chen Chen and Dao Wen Wang Tags: Original investigation Source Type: research

Prognostic impact of carotid intima-media thickness and carotid plaques on the development of micro- and macrovascular complications in individuals with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study
The prognostic importance of carotid atherosclerosis in individuals with diabetes is unsettled. We aimed to evaluate the relationships between parameters of carotid atherosclerosis and the future occurrence of... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 10, 2019 Category: Cardiology Authors: Claudia R. L. Cardoso, Guilherme C. Salles, Nathalie C. Leite and Gil F. Salles Tags: Original investigation Source Type: research

Epicardial fat tissue in patients with diabetes mellitus: a systematic review and meta-analysis
Epicardial fat tissue (EFT) is the visceral fat distributed along the coronary arteries between the pericardium and the myocardium. Increases in EFT are closely related to the occurrence of diabetes mellitus (... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 10, 2019 Category: Cardiology Authors: Yingrui Li, Bin Liu, Yu Li, Xiaodong Jing, Songbai Deng, Yulin Yan and Qiang She Tags: Original investigation Source Type: research

Targeting the glucagon receptor improves cardiac function and enhances insulin sensitivity following a myocardial infarction
In heart failure the myocardium becomes insulin resistant which negatively influences cardiac energy metabolism and function, while increasing cardiac insulin signalling improves cardiac function and prevents ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - January 9, 2019 Category: Cardiology Authors: Qutuba G. Karwi, Liyan Zhang, Cory S. Wagg, Wang Wang, Manoj Ghandi, Dung Thai, Hai Yan, John R. Ussher, Gavin Y. Oudit and Gary D. Lopaschuk Tags: Original investigation Source Type: research

A 23-year study of mortality and development of co-morbidities in patients with obesity undergoing bariatric surgery (laparoscopic gastric banding) in comparison with medical treatment of obesity
Several studies have shown that bariatric surgery reduces long term mortality compared to medical weight loss therapy. In a previous study we have demonstrated that gastric banding (LAGB) is associated with re... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 29, 2018 Category: Cardiology Authors: Antonio E. Pontiroli, Ahmed S. Zakaria, Marco Fanchini, Chiara Osio, Elena Tagliabue, Giancarlo Micheletto, Alessandro Saibene and Franco Folli Tags: Original investigation Source Type: research

Correction to: Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up
Following publication of the original article [1], the authors reported an error in Acknowledgment section. The last sentence should read as “All authors have read and approval the submission to Cardiovascular... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 27, 2018 Category: Cardiology Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabr ò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro M Tags: Correction Source Type: research

Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits
In this study, we hypothesized that alogliptin prevents diastolic dysfun... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 27, 2018 Category: Cardiology Authors: Xiaowei Zhang, Zhiwei Zhang, Yajuan Yang, Ya Suo, Ruimeng Liu, Jiuchun Qiu, Yungang Zhao, Ning Jiang, Changle Liu, Gary Tse, Guangping Li and Tong Liu Tags: Original investigation Source Type: research

Low cholesterol efflux capacity and abnormal lipoprotein particles in youth with type 1 diabetes: a case control study
Patients with type 1 diabetes (T1DM) have increased mortality from cardiovascular disease (CVD). Risk factors for CVD include an elevation of LDL (LDLp) and small HDL (sHDLp) particles, and a decrease in rever... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2018 Category: Cardiology Authors: Evgenia Gourgari, Martin P. Playford, Umberto Campia, Amit K. Dey, Fran Cogen, Stephanie Gubb-Weiser, Mihriye Mete, Sameer Desale, Maureen Sampson, Allen Taylor, Kristina I. Rother, Alan T. Remaley and Nehal N. Mehta Tags: Original investigation Source Type: research

GLP-1RAs in type 2 diabetes: mechanisms that underlie cardiovascular effects and overview of cardiovascular outcome data
Patients with type 2 diabetes (T2DM) have a substantial risk of developing cardiovascular disease. The strong connection between the severity of hyperglycaemia, metabolic changes secondary to T2DM and vascular... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2018 Category: Cardiology Authors: Andrei C. Sposito, Ot ávio Berwanger, Luiz Sérgio F. de Carvalho and José Francisco Kerr Saraiva Tags: Review Source Type: research

Associations between epicardial adipose tissue, subclinical atherosclerosis and high-density lipoprotein composition in type 1 diabetes
The pathophysiology of cardiovascular complications in people with type 1 diabetes (T1DM) remains unclear. An increase in epicardial adipose tissue (EAT) and alterations in the composition of high-density lipo... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 7, 2018 Category: Cardiology Authors: Cristina Colom, David Vilad és, Montserrat Pérez-Cuellar, Rubén Leta, Andrea Rivas-Urbina, Gemma Carreras, Jordi Ordóñez-Llanos, Antonio Pérez and Jose Luis Sánchez-Quesada Tags: Original investigation Source Type: research

Effect of statins on fasting glucose in non-diabetic individuals: nationwide population-based health examination in Korea
Increasing evidence suggest that statin therapy has a diabetogenic effect. Individual types of statin may have a different effect on glucose metabolism. Using the repeated nationwide population-based health sc... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 5, 2018 Category: Cardiology Authors: Jinkwon Kim, Hye Sun Lee and Kyung-Yul Lee Tags: Original investigation Source Type: research

Cognitive function in adolescence and the risk for premature diabetes and cardiovascular mortality in adulthood
This study asses... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 5, 2018 Category: Cardiology Authors: Gilad Twig, Amir Tirosh, Estela Derazne, Ziona Haklai, Nehama Goldberger, Arnon Afek, Hertzel C. Gerstein, Jeremy D. Kark and Tali Cukierman-Yaffe Tags: Original investigation Source Type: research

Empagliflozin on top of metformin treatment improves arterial function in patients with type 1 diabetes mellitus
Deteriorated arterial function and high incidence of cardiovascular events characterise diabetes mellitus. Metformin and recent antidiabetic drugs, SGLT2 inhibitors, reduce cardiovascular events. We explored t... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 3, 2018 Category: Cardiology Authors: Mojca Lunder, Miodrag Jani ć, Miha Japelj, Andrej Juretič, Andrej Janež and Mišo Šabovič Tags: Original investigation Source Type: research

Impact of type 2 diabetes mellitus on short- and long-term mortality after coronary artery bypass surgery
Type 2 diabetes mellitus (DM) is a frequent co-morbidity among patients undergoing coronary artery bypass grafting (CABG) surgery. The aim of this study was to evaluate the impact of DM on the early- and long-... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 29, 2018 Category: Cardiology Authors: Alexander Kogan, Eilon Ram, Shany Levin, Enrique Z. Fisman, Alexander Tenenbaum, Ehud Raanani and Leonid Sternik Tags: Original investigation Source Type: research

Thrombus aspiration in hyperglycemic ST-elevation myocardial infarction (STEMI) patients: clinical outcomes at 1-year follow-up
We evaluate whether the thrombus aspiration (TA) before primary percutaneous coronary intervention (PPCI) may improve STEMI outcomes in hyperglycemic patients. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 29, 2018 Category: Cardiology Authors: Celestino Sardu, Michelangela Barbieri, Maria Luisa Balestrieri, Mario Siniscalchi, Pasquale Paolisso, Paolo Calabr ò, Fabio Minicucci, Giuseppe Signoriello, Michele Portoghese, Pasquale Mone, Davide D’Andrea, Felice Gragnano, Alessandro Bellis, Ciro M Tags: Original investigation Source Type: research

Vascular complications in patients with type 2 diabetes: prevalence and associated factors in 38 countries (the DISCOVER study program)
The global prevalence of type 2 diabetes-related complications is not well described. We assessed prevalence of vascular complications at baseline in DISCOVER (NCT02322762; NCT02226822), a global, prospective,... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 28, 2018 Category: Cardiology Authors: Mikhail Kosiborod, Marilia B. Gomes, Antonio Nicolucci, Stuart Pocock, Wolfgang Rathmann, Marina V. Shestakova, Hirotaka Watada, Iichiro Shimomura, Hungta Chen, Javier Cid-Ruzafa, Peter Fenici, Niklas Hammar, Filip Surmont, Fengming Tang and Kamlesh Khunt Tags: Original investigation Source Type: research

Does glucagon have a positive inotropic effect in the human heart?
Glucagon is considered to exert cardiostimulant effects, most notably the enhancement of heart rate and contractility, due to the stimulation of glucagon receptors associated with Gs protein stimulation which ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 27, 2018 Category: Cardiology Authors: Jesus Hern ández-Cascales Tags: Commentary Source Type: research

Prevalence and in-hospital outcomes of diabetes among patients with acute coronary syndrome in China: findings from the Improving Care for Cardiovascular Disease in China-Acute Coronary Syndrome Project
Guidelines have classified patients with acute coronary syndrome (ACS) and diabetes as a special population, with specific sections presented for the management of these patients considering their extremely hi... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 27, 2018 Category: Cardiology Authors: Mengge Zhou, Jing Liu, Yongchen Hao, Jun Liu, Yong Huo, Sidney C. Smith Jr., Junbo Ge, Changsheng Ma, Yaling Han, Gregg C. Fonarow, Kathryn A. Taubert, Louise Morgan, Na Yang, Yueyan Xing and Dong Zhao Tags: Original investigation Source Type: research

Increased glycated albumin and decreased esRAGE levels in serum are related to negative coronary artery remodeling in patients with type 2 diabetes: an Intravascular ultrasound study
Negative coronary artery remodeling is frequent in patients with diabetes, but its mechanism remains unclear. We here evaluated the association of serum levels of glycated albumin (GA) and endogenous secretory... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 27, 2018 Category: Cardiology Authors: Run Du, Rui Yan Zhang, Lin Lu, Ying Shen, Li Jin Pu, Zheng Bin Zhu, Qi Zhang, Jian Hu, Zhen Kun Yang, Feng Hua Ding, Jian Sheng Zhang and Wei Feng Shen Tags: Original investigation Source Type: research

Polyhedrocytes in blood clots of type 2 diabetic patients with high cardiovascular risk: association with glycemia, oxidative stress and platelet activation
Little is known about factors that affect the composition of contracted blood clots in specific diseases. We investigated the content of polyhedral erythrocytes (polyhedrocytes) formed in blood clots and its d... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 22, 2018 Category: Cardiology Authors: Grzegorz Gajos, Aleksander Siniarski, Joanna Natorska, Micha ł Ząbczyk, Jakub Siudut, Krzysztof Piotr Malinowski, Renata Gołębiowska-Wiatrak, Paweł Rostoff and Anetta Undas Tags: Original investigation Source Type: research

Unrecognised cardiovascular disease in type 2 diabetes: is it time to act earlier?
Cardiovascular disease (CVD) is the most significant prognostic factor in individuals with type 2 diabetes (T2D). However, a significant number of individuals may develop CVD that does not present with the cla... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 21, 2018 Category: Cardiology Authors: Guntram Schernthaner, Chaim Lotan, Elina Baltadzhieva-Trendafilova, Jonas Ceponis, Martin Clodi, Kristine Ducena, Eva Goncalvesova, Cristian Guja, Marek Honka, Andrej Jane ž, Nebojša Lalić, Roger Lehmann, Noémi Nyolczas, Priit Pauklin, Andrzej Rynkiew Tags: Commentary Source Type: research

A SGLT2 inhibitor dapagliflozin suppresses prolonged ventricular-repolarization through augmentation of mitochondrial function in insulin-resistant metabolic syndrome rats
Metabolic syndrome (MetS) is a prevalent risk factor for cardiac dysfunction. Although SGLT2-inhibitors have important cardioprotective effects in hyperglycemia, their underlying mechanisms are complex and not... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 17, 2018 Category: Cardiology Authors: Aysegul Durak, Yusuf Olgar, Sinan Degirmenci, Erman Akkus, Erkan Tuncay and Belma Turan Tags: Original investigation Source Type: research

Correlations between serum concentration of three bone-derived factors and obesity and visceral fat accumulation in a cohort of middle aged men and women
The aim of this study was to investigate the interrelationships between three bone-derived factors [serum osteocalcin (OCN), fibroblast growth factor (FGF) 23, and neutrophil gelatinase-associated lipocalin (N... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 13, 2018 Category: Cardiology Authors: Yiting Xu, Xiaojing Ma, Xiaoping Pan, Xingxing He, Yunfeng Xiao and Yuqian Bao Tags: Original investigation Source Type: research

The negative effect of ANGPTL8 on HDL-mediated cholesterol efflux capacity
It is well known that angiopoietin-like protein 8 (ANGPTL8) exerts its effects on lipid metabolism through the inhibition of lipoprotein lipase and subsequent elevation of plasma triglyceride. However, it is n... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 8, 2018 Category: Cardiology Authors: Mengdie Luo, Ziyu Zhang, Yani Peng, Shuai Wang and Daoquan Peng Tags: Original investigation Source Type: research

Platelet activity and hypercoagulation in type 2 diabetes
A strong correlation exists between type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD), with CVD and the presence of atherosclerosis being the prevailing cause of morbidity and mortality in diabe... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 2, 2018 Category: Cardiology Authors: Lesha Pretorius, Greig J. A. Thomson, Rozanne C. M. Adams, Theo A. Nell, Willem A. Laubscher and Etheresia Pretorius Tags: Original investigation Source Type: research

Impact of intravenous exenatide infusion for perioperative blood glucose control on myocardial ischemia-reperfusion injuries after coronary artery bypass graft surgery: sub study of the phase II/III ExSTRESS randomized trial
The aim of the study was to investigate whether intravenous (iv) infusion of exenatide, a synthetic GLP-1 receptor agonist, could provide a protective effect against myocardial ischemia-reperfusion injury afte... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - November 1, 2018 Category: Cardiology Authors: Guillaume Besch, Andrea Perrotti, Lucie Salomon du Mont, Marc Puyraveau, Xavier Ben-Said, Maude Baltres, Benoit Barrucand, Guillaume Flicoteaux, Lucie Vettoretti, Emmanuel Samain, Sidney Chocron and Sebastien Pili-Floury Tags: Original investigation Source Type: research

Left ventricular subclinical myocardial dysfunction in uncomplicated type 2 diabetes mellitus is associated with impaired myocardial perfusion: a contrast-enhanced cardiovascular magnetic resonance study
Early detection of subclinical myocardial dysfunction in patients with diabetes mellitus (DM) is essential for recommending therapeutic interventions that can prevent or reverse heart failure, thereby improvin... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 30, 2018 Category: Cardiology Authors: Xi Liu, Zhi-gang Yang, Yue Gao, Lin-jun Xie, Li Jiang, Bi-yue Hu, Kai-yue Diao, Ke Shi, Hua-yan Xu, Meng-ting Shen, Yan Ren and Ying-kun Guo Tags: Original investigation Source Type: research

Lower extremity arterial disease in patients with diabetes: a contemporary narrative review
Lower-extremity arterial disease (LEAD) is a major endemic disease with an alarming increased prevalence worldwide. It is a common and severe condition with excess risk of major cardiovascular events and death... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 23, 2018 Category: Cardiology Authors: Mathilde Nativel, Louis Potier, Laure Alexandre, Laurence Baillet-Blanco, Eric Ducasse, Gilberto Velho, Michel Marre, Ronan Roussel, Vincent Rigalleau and Kamel Mohammedi Tags: Review Source Type: research

Cardiac resynchronization therapy with a defibrillator (CRTd) in failing heart patients with type 2 diabetes mellitus and treated by glucagon-like peptide 1 receptor agonists (GLP-1 RA) therapy vs. conventional hypoglycemic drugs: arrhythmic burden, hospitalizations for heart failure, and CRTd responders rate
To evaluate clinical outcomes in patients with diabetes, treated by cardiac resynchronization therapy with a defibrillator (CRT-d), and glucagon-like peptide 1 receptor agonists (GLP-1 RA) in addition to conve... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 22, 2018 Category: Cardiology Authors: Celestino Sardu, Pasquale Paolisso, Cosimo Sacra, Matteo Santamaria, Claudio de Lucia, Antonio Ruocco, Ciro Mauro, Giuseppe Paolisso, Maria Rosaria Rizzo, Michelangela Barbieri and Raffaele Marfella Tags: Original investigation Source Type: research

Hyperglycemia and risk of ventricular tachycardia among patients hospitalized with acute myocardial infarction
Little is known about the association of hyperglycemia with the development of ventricular tachycardia (VT) in patients hospitalized with acute myocardial infarction (AMI) which we examined in the present stud... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 19, 2018 Category: Cardiology Authors: Hoang V. Tran, Joel M. Gore, Chad E. Darling, Arlene S. Ash, Catarina I. Kiefe and Robert J. Goldberg Tags: Original investigation Source Type: research

Impact of type 2 diabetes mellitus in the utilization and in-hospital outcomes of surgical aortic valve replacement in Spain (2001 –2015)
The aims of this study were to examine trends in the incidence and in-hospital outcomes of SAVR among T2DM patients from 2001 to 2015, to compare clinical variables among T2DM patients and matched non-T2DM pat... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 16, 2018 Category: Cardiology Authors: Ana L ópez-de-Andrés, Napoleon Perez-Farinos, Javier de Miguel-Díez, Valentín Hernández-Barrera, Manuel Méndez-Bailón, José M. de Miguel-Yanes and Rodrigo Jiménez-García Tags: Original investigation Source Type: research

Perivascular adipose tissue (PVAT) in atherosclerosis: a double-edged sword
Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the vasculature, has emerged as an active component of the blood vessel wall regulating vascular homeostasis and affecting the path... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 10, 2018 Category: Cardiology Authors: Xiao-Yan Qi, Shun-Lin Qu, Wen-Hao Xiong, Oren Rom, Lin Chang and Zhi-Sheng Jiang Tags: Review Source Type: research

Rising plasminogen activator inhibitor-1 and hypoadiponectinemia characterize the cardiometabolic biomarker profile of women with recent gestational diabetes
Gestational diabetes (GDM) and milder gestational impaired glucose tolerance (GIGT) identify women at risk of developing type 2 diabetes and cardiovascular disease later in life. Accordingly, the postpartum ye... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 9, 2018 Category: Cardiology Authors: Sadia Mehmood, Chang Ye, Philip W. Connelly, Anthony J. Hanley, Bernard Zinman and Ravi Retnakaran Tags: Original investigation Source Type: research

Impact of dapagliflozin on left ventricular diastolic function of patients with type 2 diabetic mellitus with chronic heart failure
The objective of this study was to investigate the impact of sodium glucose cotransporter type 2 (SGLT2) inhibitors on left ventricular (LV) diastolic function of type 2 diabetes mellitus (T2DM) patients with ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - October 8, 2018 Category: Cardiology Authors: Fumitaka Soga, Hidekazu Tanaka, Kazuhiro Tatsumi, Yasuhide Mochizuki, Hiroyuki Sano, Hiromi Toki, Kensuke Matsumoto, Junya Shite, Hideyuki Takaoka, Tomofumi Doi and Ken-ichi Hirata Tags: Original investigation Source Type: research

Impaired glucose metabolism is associated with increased thrombin generation potential in patients undergoing angioplasty and stenting
As a strong platelet agonist on the one hand and key molecule in plasmatic coagulation on the other hand, thrombin connects primary and secondary hemostasis. Thrombin generation potential reflects the individu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 29, 2018 Category: Cardiology Authors: Silvia Lee, Cihan Ay, Christoph W. Kopp, Simon Panzer and Thomas Gremmel Tags: Original investigation Source Type: research

Effects of oral antidiabetic drugs on left ventricular mass in patients with type 2 diabetes mellitus: a network meta-analysis
We used a network meta-analysis of randomized controlled trials (RCTs) to comparatively examine the effects of oral antidiabetic drugs (OADs) on left ventricular mass (LVM) in patients with type 2 diabetes. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 27, 2018 Category: Cardiology Authors: Satoshi Ida, Ryutaro Kaneko and Kazuya Murata Tags: Original investigation Source Type: research

Both pre-frailty and frailty increase healthcare utilization and adverse health outcomes in patients with type 2 diabetes mellitus
Diabetes mellitus (DM) correlates with accelerated aging and earlier appearance of geriatric phenotypes, including frailty. However, whether pre-frailty or frailty predicts greater healthcare utilization in di... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 27, 2018 Category: Cardiology Authors: Chia-Ter Chao, Jui Wang and Kuo-Liong Chien Tags: Original investigation Source Type: research

Early vascular parameters in the micro- and macrocirculation in type 2 diabetes
Diabetes converts from a metabolic disorder into a predominantly vascular disease, once its duration extends over several years or/and when additional cardiovascular risk factors such as hypertension coexist. ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 19, 2018 Category: Cardiology Authors: Dennis Kannenkeril, Agnes Bosch, Joanna Harazny, Marina Karg, Susanne Jung, Christian Ott and Roland E. Schmieder Tags: Original investigation Source Type: research

ACE2 polymorphisms associated with cardiovascular risk in Uygurs with type 2 diabetes mellitus
Type 2 diabetes mellitus (T2D), rapidly increasing to epidemic proportions, globally escalates cardiovascular disease risk. Although intensive interventions and comprehensive management of environmental risks ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 18, 2018 Category: Cardiology Authors: Cheng Liu, Yanfang Li, Tianwang Guan, Yanxian Lai, Yan Shen, Abudurexiti Zeyaweiding, Haiyan Zhao, Fang Li and Tutiguli Maimaiti Tags: Original investigation Source Type: research

The role of physical activity in the development of first cardiovascular disease event: a tree-structured survival analysis of the Danish ADDITION-PRO cohort
We examined the interplay between PA dimensions and more conventional CVD risk factors to ass... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 12, 2018 Category: Cardiology Authors: Hanan Amadid, Nanna B. Johansen, Anne-Louise Bjerregaard, S øren Brage, Kristine Færch, Torsten Lauritzen, Daniel R. Witte, Annelli Sandbæk, Marit E. Jørgensen and Dorte Vistisen Tags: Original investigation Source Type: research

Type 2 diabetes is independently associated with all-cause mortality secondary to ventricular tachyarrhythmias
The study sought to assess the prognostic impact of type 2 diabetes in patients presenting with ventricular tachyarrhythmias on admission. (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 10, 2018 Category: Cardiology Authors: Kathrin Weidner, Michael Behnes, Tobias Schupp, Jonas Rusnak, Linda Reiser, Armin Bollow, Gabriel Taton, Thomas Reichelt, Dominik Ellguth, Niko Engelke, Jorge Hoppner, Ibrahim El-Battrawy, Kambis Mashayekhi, Christel Wei ß, Martin Borggrefe and Ibrahim A Tags: Original investigation Source Type: research

Midlife development of type 2 diabetes and hypertension in women by history of hypertensive disorders of pregnancy
Women with history of hypertensive disorders of pregnancy (HDP) are at increased risk of early onset cardiovascular disease and type 2 diabetes (T2D). We aimed to investigate the extent to which HDP is also as... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - September 10, 2018 Category: Cardiology Authors: Simon Timpka, Amanda Markovitz, Tommy Schyman, Ingrid Mogren, Abigail Fraser, Paul W. Franks and Janet W. Rich-Edwards Tags: Original investigation Source Type: research