Combined effect of adiposity and elevated inflammation on incident type 2 diabetes: a prospective cohort study
Adiposity and elevated inflammation are two hallmarks of hyperglycemia. However, it is unknown whether clustering of elevated inflammation and adiposity interact act on diabetogenesis and lead to a greater ris... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Dan Wu, Yulong Lan, Shuohua Chen, Xiong Ding, Guanzhi Chen, Chutao Wu, Lois Balmer, Wencan Xu, Shouling Wu and Wei Wang Tags: Research Source Type: research

Primary aldosteronism and lower-extremity arterial disease: a two-sample Mendelian randomization study
Primary aldosteronism (PA) is an adrenal disorder of autonomous aldosterone secretion which promotes arterial injury. We aimed to explore whether PA is causally associated with lower-extremity arterial disease... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 20, 2023 Category: Cardiology Authors: Jinbo Hu, Qinglian Zeng, Xiangjun Chen, Wenjin Luo, Ziwei Tang, Mei Mei, Wenrui Zhao, Zhipeng Du, Zhiping Liu, Qifu Li, Qingfeng Cheng and Shumin Yang Tags: Research Source Type: research

Dapagliflozin treatment is associated with a reduction of epicardial adipose tissue thickness and epicardial glucose uptake in human type 2 diabetes
We recently demonstrated that treatment with sodium-glucose cotransporter-2 inhibitors (SGLT-2i) leads to an increase in myocardial flow reserve in patients with type 2 diabetes (T2D) with stable coronary arte... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Francesca Cinti, Lucia Leccisotti, Gian Pio Sorice, Umberto Capece, Domenico D ’Amario, Margherita Lorusso, Shawn Gugliandolo, Cassandra Morciano, Andrea Guarneri, Maria Angela Guzzardi, Teresa Mezza, Amedeo Capotosti, Luca Indovina, Pietro Manuel Ferra Tags: Research Source Type: research

Early insulin resistance in normoglycemic low-risk individuals is associated with subclinical atherosclerosis
Elevated glycated hemoglobin (HbA1c) is associated with a higher burden of subclinical atherosclerosis (SA). However, the association with SA of earlier insulin resistance markers is poorly understood. The stu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Josep Iglesies-Grau, Ana Garcia-Alvarez, Bel én Oliva, Guiomar Mendieta, Inés García-Lunar, José J. Fuster, Ana Devesa, Cristina Pérez-Herreras, Antonio Fernández-Ortiz, Ramon Brugada, Borja Ibanez, Rodrigo Fernandez-Jimenez and Valentin Fuster Tags: Research Source Type: research

Prediabetes increases the risk of major limb and cardiovascular events
Prediabetes, an intermediate stage between normal blood sugar levels and a diabetes mellitus diagnosis, is increasing in prevalence. Severe prediabetes is associated with a similar risk of complications as dia... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 19, 2023 Category: Cardiology Authors: Jung-Chi Hsu, Yen-Yun Yang, Shu-Lin Chuang, Jen-Kuang Lee and Lian-Yu Lin Tags: Research Source Type: research

The triglyceride glucose index trajectory is associated with hypertension: a retrospective longitudinal cohort study
Previous studies have found that the triglyceride glucose index (TyG index) trajectories are associated with cardiovascular diseases. However, the association between the patterns of TyG index trajectories and... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 15, 2023 Category: Cardiology Authors: Fengling Xin, Shuyou He, Yu Zhou, Xueni Jia, Yulong Zhao and Hui Zhao Tags: Research Source Type: research

Olive oil consumption, plasma metabolites, and risk of type 2 diabetes and cardiovascular disease
Olive oil consumption has been inversely associated with the risk of type 2 diabetes (T2D) and cardiovascular disease (CVD). However, the impact of olive oil consumption on plasma metabolites remains poorly un... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2023 Category: Cardiology Authors: Jes ús F. García-Gavilán, Nancy Babio, Estefanía Toledo, Zhila Semnani-Azad, Cristina Razquin, Courtney Dennis, Amy Deik, Dolores Corella, Ramón Estruch, Emilio Ros, Montserrat Fitó, Fernando Arós, Miquel Fiol, José Lapetra, Rosa Lamuela-Raventos, Tags: Research Source Type: research

Incident cardiac arrhythmias associated with metabolic dysfunction-associated steatotic liver disease: a nationwide histology cohort study
Prior studies suggest a link between metabolic dysfunction-associated steatotic liver disease (MASLD) and incident arrhythmias, including atrial fibrillation (AF). However, robust data are lacking from cohorts... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2023 Category: Cardiology Authors: Tracey G. Simon, Fahim Ebrahimi, Bjorn Roelstraete, Hannes Hagstr öm, Johan Sundström and Jonas F. Ludvigsson Tags: Research Source Type: research

Cardiovascular risk and renal injury profile in subjects with type 2 diabetes and non-albuminuric diabetic kidney disease
In the last years, the classical pattern of diabetic kidney disease (DKD) has been partially overcome, because of the uncovering of a new DKD phenotype with significant renal dysfunction without presence of al... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2023 Category: Cardiology Authors: Maurizio Di Marco, Sabrina Scilletta, Nicoletta Miano, Nicola Marrano, Annalisa Natalicchio, Francesco Giorgino, Stefania Di Mauro, Agnese Filippello, Alessandra Scamporrino, Paola Tribulato, Giosiana Bosco, Francesco Di Giacomo Barbagallo, Roberto Scical Tags: Research Source Type: research

Obesity indices and the risk of total and cardiovascular mortality among people with diabetes: a long-term follow-up study in Taiwan
The association between obesity indicators and mortality in individuals with diabetes remains unclear, and data on cardiovascular mortality are scarce. Therefore, we investigated the associations between the f... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2023 Category: Cardiology Authors: Chung-Yen Lu, Hsiao-Hui Chen, Kuan-Hui Chi and Pei-Chun Chen Tags: Research Source Type: research

Triglyceride-glucose index is associated with a higher risk of stroke in a hypertensive population
This study aimed to evaluate the association of triglyceride-glucose (TyG) index, an insulin resistance surrogate biomarker, with first stroke in a hypertensive population and to explore potential influencing ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 13, 2023 Category: Cardiology Authors: Nan Zhang, Xiying Chi, Ziyi Zhou, Yun Song, Shuqun Li, Jiafeng Xu and Jianping Li Tags: Research Source Type: research

Opposite causal effects of birthweight on myocardial infarction and atrial fibrillation and the distinct mediating pathways: a Mendelian randomization study
Previous observational studies have documented an inverse association of birthweight with myocardial infarction (MI) but a positive association with atrial fibrillation (AF). However, the causality of these as... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 12, 2023 Category: Cardiology Authors: Lijie Kong, Yiying Wang, Chaojie Ye, Chun Dou, Dong Liu, Min Xu, Jie Zheng, Ruizhi Zheng, Yu Xu, Mian Li, Zhiyun Zhao, Jieli Lu, Yuhong Chen, Weiqing Wang, Ruixin Liu, Yufang Bi & hellip; Tags: Research Source Type: research

Isthmin-1 (ISM1), a novel adipokine that reflects abdominal adipose tissue distribution in individuals with obesity
The assessment of obesity-related health risks has traditionally relied on the Body Mass Index and waist circumference, but their limitations have propelled the need for a more comprehensive approach. The diff... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 8, 2023 Category: Cardiology Authors: Marta Lopez-Yus, Carmen Casamayor, Juan Jose Soriano-Godes, Sofia Borlan, Yolanda Gonzalez-Irazabal, Maria Pilar Garcia-Sobreviela, Beatriz Garcia-Rodriguez, Raquel del Moral-Bergos, Pilar Calmarza, Jose Maria Artigas, Silvia Lorente-Cebrian, Vanesa Berna Tags: Research Source Type: research

Effects of diabetes mellitus and glycemic traits on cardiovascular morpho-functional phenotypes
The effects of diabetes on the cardiac and aortic structure and function remain unclear. Detecting and intervening these variations early is crucial for the prevention and management of complications. Cardiova... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 8, 2023 Category: Cardiology Authors: Zhaoyue Li, Jie Xiong, Yutong Guo, Hao Tang, Bingchen Guo, Bo Wang, Dianyu Gao, Zengxiang Dong and Yingfeng Tu Tags: Research Source Type: research

Effects of exenatide on coronary stent ’s endothelialization in subjects with type 2 diabetes: a randomized controlled trial. The Rebuild study
Subjects with type 2 diabetes (T2D) have a higher risk of in-stent restenosis and stent thrombosis. The activation of the glucagon-like peptide-1 receptor (GLP-1R) has been suggested to induce several effects ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - December 8, 2023 Category: Cardiology Authors: Irene Santos-Pardo, Nils Witt, Oskar Anger ås and Thomas Nyström Tags: Research Source Type: research