Impact of glycated hemoglobin on 2-year clinical outcomes in elderly patients with atrial fibrillation: sub-analysis of ANAFIE Registry, a large observational study
This ANAFIE Registry sub-analysis investigated 2-year outcomes and oral anticoagulant (OAC) use stratified by glycated hemoglobin (HbA1c) levels among Japanese patients aged  ≥ 75 years with non-valvular atrial... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 12, 2023 Category: Cardiology Authors: Yasuo Terauchi, Hiroshi Inoue, Takeshi Yamashita, Masaharu Akao, Hirotsugu Atarashi, Takanori Ikeda, Yukihiro Koretsune, Ken Okumura, Shinya Suzuki, Hiroyuki Tsutsui, Kazunori Toyoda, Atsushi Hirayama, Masahiro Yasaka, Takenori Yamaguchi, Satoshi Teramuka Tags: Research Source Type: research

Insulin growth factor axis and cardio-renal risk in diabetic kidney disease: an analysis from the CREDENCE trial
The insulin-like growth factors (IGF) play a crucial role in regulating cellular proliferation, apoptosis, and key metabolic pathways. The ratio of IGF-1 to IGF binding protein-3 (IGFBP-3) is an important fact... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 12, 2023 Category: Cardiology Authors: Reza Mohebi, Yuxi Liu, Michael K. Hansen, Yshai Yavin, Naveed Sattar, Carol A. Pollock, Javed Butler, Meg Jardine, Serge Masson, Hiddo J. L. Heerspink and James L. Januzzi Jr Tags: Research Source Type: research

Association between the triglyceride –glucose index and the risk of mortality among patients with chronic heart failure: results from a retrospective cohort study in China
The triglyceride –glucose (TyG) index has been demonstrated to be a reliable surrogate marker of insulin resistance (IR) and an effective predictive index of cardiovascular (CV) disease risk. However, its long-... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 7, 2023 Category: Cardiology Authors: You Zhou, Chi Wang, Hebin Che, Liting Cheng, Di Zhu, Chongyou Rao, Qin Zhong, Zongren Li, Xiao Wang, Zisheng Wu and Kunlun He Tags: Research Source Type: research

CXCL5 suppression recovers neovascularization and accelerates wound healing in diabetes mellitus
This study aimed to explore the impacts... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 7, 2023 Category: Cardiology Authors: Ching Chen, Liang-Yu Lin, Jaw-Wen Chen and Ting-Ting Chang Tags: Research Source Type: research

Visit-to-visit HbA1c variability is associated with aortic stiffness progression in participants with type 2 diabetes
This study aims to determine whether long-term visit-to-visit glycemic variability is associated with aortic sti... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2023 Category: Cardiology Authors: Qianhua Fang, Juan Shi, Jia Zhang, Ying Peng, Cong Liu, Xing Wei, Zhuomeng Hu, Lin Sun, Jie Hong, Weiqiong Gu, Weiqing Wang and Yifei Zhang Tags: Research Source Type: research

Dysregulated Rbfox2 produces aberrant splicing of CaV1.2 calcium channel in diabetes-induced cardiac hypertrophy
L-type Ca2+ channel CaV1.2 is essential for cardiomyocyte excitation, contraction and gene transcription in the heart, and abnormal functions of cardiac CaV1.2 channels are presented in diabetic cardiomyopathy. H... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2023 Category: Cardiology Authors: Pengpeng Li, Dongxia Qin, Tiange Chen, Wei Hou, Xinyu Song, Shumin Yin, Miaomiao Song, W.C. Hewith A. Fernando, Xiaojie Chen, Yu Sun and Juejin Wang Tags: Research Source Type: research

Both LDL and HDL particle concentrations associate positively with an increased risk of developing microvascular complications in patients with type 2 diabetes: lost protection by HDL (Zodiac-63)
Triglyceride-rich lipoproteins (TRL) and low-density lipoproteins (LDL) are associated positively whereas high-density lipoproteins (HDL) are associated inversely with the development of new-onset type 2 diabe... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 6, 2023 Category: Cardiology Authors: Arno R. Bourgonje, Margery A. Connelly, Harry van Goor, Peter R. van Dijk and Robin P. F. Dullaart Tags: Research Source Type: research

Impact of the SGLT2-inhibitor empagliflozin on inflammatory biomarkers after acute myocardial infarction – a post-hoc analysis of the EMMY trial
SGTL2-inhibitors are a cornerstone in the treatment of heart failure, but data on patients with acute myocardial infarction (AMI) is limited. The EMMY trial was the first to show a significant reduction in NTp... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 5, 2023 Category: Cardiology Authors: Martin Benedikt, Harald Mangge, Faisal Aziz, Pero Curcic, Sabine Pailer, Markus Herrmann, Ewald Kolesnik, Norbert J. Tripolt, Peter N. Pferschy, Markus Wallner, Andreas Zirlik, Harald Sourij and Dirk von Lewinski Tags: Research Source Type: research

The impact of fasting stress hyperglycemia ratio, fasting plasma glucose and hemoglobin A1c on in-hospital mortality in patients with and without diabetes: findings from the China acute myocardial infarction registry
Stress hyperglycemia was positively associated with poor prognosis in individuals with acute myocardial infarction (AMI). However, admission glucose and stress hyperglycemia ratio (SHR) may not be the best ind... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - July 4, 2023 Category: Cardiology Authors: Kongyong Cui, Rui Fu, Jingang Yang, Haiyan Xu, Dong Yin, Weihua Song, Hongjian Wang, Chenggang Zhu, Lei Feng, Zhifang Wang, Qingsheng Wang, Ye Lu, Kefei Dou and Yuejin Yang Tags: Research Source Type: research

Effect of onset of type 2 diabetes on risks of cardiovascular disease and heart failure among new Zealanders with impaired glucose tolerance over 25 years: tapered-matched landmark analysis
This study aimed to examine the association between the incident onset of T2DM and 5- and 10-year risks of CVD and HF in people with IGT identified in primary care in South and West Auckland, New Zealand (NZ) ... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 30, 2023 Category: Cardiology Authors: Dahai Yu, Bingjie Qu, Uchechukwu Levi Osuagwu, Karen Pickering, John Baker, Richard Cutfield MBChB, Yamei Cai, Brandon J Orr-Walker, Gerhard Sundborn, Zhanzheng Zhao and David Simmons Tags: Research Source Type: research

Pathophysiological basis of the cardiological benefits of SGLT-2 inhibitors: a narrative review
In recent years, GLP-1 receptor agonists (GLP-1RA), and SGLT-2 inhibitors (SGLT-2i) have become available, which have become valuable additions to therapy for type 2 diabetes as they are associated with low ri... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 30, 2023 Category: Cardiology Authors: Cristina Panico, Benedetta Bonora, Antonella Camera, Nino Cristiano Chilelli, Giuliana Da Prato, Giuseppe Favacchio, Valeria Grancini, Veronica Resi, Maurizio Rondinelli, Emanuela Zarra and Basilio Pintaudi Tags: Review Source Type: research

Correction: Prediabetes and all-cause mortality in young patients undergoing coronary artery angiography: a multicenter cohort study in China
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 29, 2023 Category: Cardiology Authors: Yibo He, Hongyu Lu, Yihang Ling, Jin Liu, Sijia Yu, Ziyou Zhou, Tian Chang, Yong Liu, Shiqun Chen and Jiyan Chen Tags: Correction Source Type: research

Non-linear association of atherogenic index of plasma with insulin resistance and type 2 diabetes: a cross-sectional study
Although there is numerous evidence on the epidemiological risk factors for insulin resistance (IR)-related metabolic diseases, there is still insufficient evidence to explore the non-linear association of Ath... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 29, 2023 Category: Cardiology Authors: Bei Yin, Zihong Wu, Yaqing Xia, Shunqiang Xiao, Lingling Chen and Yousheng Li Tags: Research Source Type: research

Correction: Comparison of 2 ‑year mortality according to obesity in stabilized patients with type 2 diabetes mellitus after acute myocardial infarction: results from the DIAMOND prospective cohort registry
(Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 29, 2023 Category: Cardiology Authors: Ki ‑Bum Won, Seung‑Ho Hur, Yun‑Kyeong Cho, Hyuck‑Jun Yoon, Chang‑Wook Nam, Kwon‑Bae Kim, Jang‑Ho Bae, Dong‑Ju Choi, Young‑Keun Ahn, Jong‑Seon Park, Hyo‑Soo Kim, Rak‑Kyeong Choi, Donghoon Choi, Joon‑Hong Kim, Kyoo‑Rok Han, Hun†Tags: Correction Source Type: research

The use of sodium-glucose co-transporter-2 inhibitors or glucagon-like peptide-1 receptor agonists versus sulfonylureas and the risk of lower limb amputations: a nation-wide cohort study
Numerous studies have investigated the potential association of sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) with an increased risk of lower limb amputations (LLAs), but have produced conflicting resu... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - June 29, 2023 Category: Cardiology Authors: Nikki C. C. Werkman, Johanna H. M. Driessen, Coen D. A. Stehouwer, Peter Vestergaard, Nicolaas C. Schaper, Joop P. van den Bergh and Johannes T. H. Nielen Tags: Research Source Type: research