ASGR1 deficiency diverts lipids toward adipose tissue but results in liver damage during obesity

Asialoglycoprotein receptor 1 (ASGR1), primarily expressed on hepatocytes, promotes the clearance and the degradation of glycoproteins, including lipoproteins, from the circulation. In humans, loss-of-function...

Source: Cardiovascular Diabetology - January 28, 2024 Category: Cardiology Authors: Monika Svecla, Lorenzo Da Dalt, Annalisa Moregola, Jasmine Nour, Andrea Baragetti, Patrizia Uboldi, Elena Donetti, Lorenzo Arnaboldi, Giangiacomo Beretta, Fabrizia Bonacina and Giuseppe Danilo Norata Tags: Research Source Type: research