Customized Citrate Anticoagulation versus No Anticoagulant in Continuous Venovenous Hemofiltration in Critically Ill Patients with Acute Kidney Injury: A Prospective Randomized Controlled Trial
Conclusion: Customized citrate-based replacement solution improved filter survival in CVVH compared to anticoagulant-free strategy. This regimen is safe, feasible, and suitable for low- to middle-income countries.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 1, 2023 Category: Hematology Source Type: research
Workshop Purification Therapies – From Research to Clinical Evidence,
Milan, Italy, September 30th – October 1st, 2022
The Aferetica team, together with all the partners and collaborators, is very glad to present the scientific contributions of The Workshop Purification Therapies - ‘From Research to Clinical Evidence’, held in Milan the 30th September and the 1st October 2022.
This edition of the Workshop is a part of a long Journey, started with the first edition in 2017, or further back in time, with the foundation of Aferetica in 2013, involving an interdisciplinary com munity of clinicians, researchers and industry partners in an innovation-oriented Collaborative Research cooperation, a concept on the basis and the origins of the g...
Source: Blood Purification - February 20, 2023 Category: Hematology Source Type: research
Point of Care Ultrasound Training in Nephrology: Twitter Poll as a Modern Tool for Development of an Effective Curriculum
Conclusions: Twitter polls aid in identifying the knowledge gaps among POCUS learners. Information obtained from the polls can be used to improve POCUS-related curricula and develop targeted educational material to facilitate remote learning.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 13, 2023 Category: Hematology Source Type: research
Workshop Purification Therapies – From Research to Clinical Evidence
Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 13, 2023 Category: Hematology Source Type: research
Pitavastatin Compared with Differential Intervention Trial by Standard Therapy on Cardiovascular Events in Patients with Dyslipidemia on Chronic Hemodialysis (DIALYSIS): A Randomized Controlled Trial
Conclusion: Our study has demonstrated that aggressive intervention with pitavastatin is more effective than the standard (dietary) therapy for improving the clinical outcomes in patients with dyslipidemia on chronic hemodialysis.Blood Purif (Source: Blood Purification)
Source: Blood Purification - January 30, 2023 Category: Hematology Source Type: research
Patient-Centered Care Could Improve Quality of Life and Survival of Dialysis Patients: Dialysis Prescription and Daily Practice
We now face a paradigm shift in clinical practice and research of dialysis from evidence-based medicine outcomes to patient-reported outcomes (PROs). It is imperative to establish a daily practice pattern based on the PROs, namely “patient-centered dialysis care.” In 2005, we introduced the concept of “patient-oriented dialysis,” which includes two fundamental components; adjustment of the dialysis prescription according to the PROs and nutritional intervention based on the global nutritional assessment. Routine exami nations and team meetings were held to monitor the status of PROs and nutrition, and intervention ...
Source: Blood Purification - January 26, 2023 Category: Hematology Source Type: research
Peritoneal Dialysis Exit-Site Care Protocols in Portugal and Its Association with Catheter-Related Infections
Conclusions: We found potential proceedings associated with ESi and peritonitis. A regular national audit of peritoneal dialysis units is an important tool for clarifying the best procedures for reduction of catheter-related infections.Blood Purif (Source: Blood Purification)
Source: Blood Purification - January 26, 2023 Category: Hematology Source Type: research
New Frontiers in Sepsis-Induced Acute Kidney Injury and Blood Purification Therapies: The Role of Polymethylmethacrylate Membrane Hemofilter
Acute kidney injury (AKI) is a common consequence of sepsis with a mortality rate of up to 40%. The pathogenesis of septic AKI is complex and involves several mechanisms leading to exacerbated inflammatory response associated with renal injury. A large body of evidence suggests that inflammation is tightly linked to AKI through bidirectional interaction between renal and immune cells. Preclinical data from our and other laboratories have identified in complement system activation a crucial mediator of AKI. Partial recovery following AKI could lead to long-term consequences that predispose to chronic dysfunction and may als...
Source: Blood Purification - January 24, 2023 Category: Hematology Source Type: research
The Investigation of Kidney Involvement in 430 Hospitalized Patients with Omicron COVID-19 in Tianjin, China
Conclusion: The majority of the patients suffered from mild or ordinary symptoms of Omicron COVID-19 infection. The primary kidney involvement was hematuria and proteinuria. Proteinuria was significantly associated with Omicron variant infection, and patients with hypertensive comorbidity, higher CRP, and higher creatinine levels were at increased risk of proteinuria after Omicron variant infection.Blood Purif (Source: Blood Purification)
Source: Blood Purification - January 19, 2023 Category: Hematology Source Type: research
Rationale for a New Classification of Solutes of Interest in Chronic Kidney Disease and Hemodialysis
A hallmark of chronic kidney disease is the retention of solutes that normally are eliminated by the kidneys. The current classification defines uremic toxins based on molecular weight and protein affinity. The retention of solutes is already detected in the early stages of the disease when patients are pauci-symptomatic or asymptomatic but the role of therapies to retard the loss of kidney function in patients with chronic kidney disease (e.g., modulators of the renin-angiotensin-aldosterone system, sodium-glucose cotransporter inhibitors) in reducing uremic toxins is poorly understood. Most of the research evaluating the...
Source: Blood Purification - January 19, 2023 Category: Hematology Source Type: research
