Adjunct Use of Continuous Renal Replacement Therapy with Extracorporeal Membrane Oxygenation Achieves Negative Fluid Balance and Enhances Oxygenation Which Improves Survival in Critically Ill Patients without Kidney Failure
Conclusions: The use of CRRT for fluid management is effective and, when resulting in negative fluid balance, improves survival in adult ECMO patients without significant renal dysfunction.Blood Purif (Source: Blood Purification)
Source: Blood Purification - September 2, 2021 Category: Hematology Source Type: research

Tandem Therapeutic Plasma Exchange Reduces Continuous Renal Replacement Therapy Downtime
Conclusions: Interruptions for TPE increase CRRT downtime. Tandem TPE significantly reduces CRRT downtime in patients undergoing both procedures concomitantly.Blood Purif (Source: Blood Purification)
Source: Blood Purification - September 1, 2021 Category: Hematology Source Type: research

Comparative Impact of Isolated Ultrafiltration and Hemodialysis on Fluid Distribution: A Bioimpedance Study
Conclusion: The extracellular fluid reduction effect of HD is stronger than that of IUF. The different changes in effective osmolality and osmolal gap after HD and IUF sessions may be related to the different effects of HD and IUF on fluid distribution.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 31, 2021 Category: Hematology Source Type: research

Publisher Correction to “Association between Procalcitonin and Acute Kidney Injury in Patients with Bacterial Septic Shock”
Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 27, 2021 Category: Hematology Source Type: research

Erratum
Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 27, 2021 Category: Hematology Source Type: research

Impact of First Wave COVID-19 Crisis on Dialysis Parameters of COVID-Free Hemodialysis Patients: A NephoCare France Longitudinal Retrospective Cohort Study
Conclusion: HD delivery to COVID-free HD patients was negatively impacted in the Paris region because of the strong constraints on units ’ organization related to the treatment of COVID-19+ HD patients and with a higher proportion of limited care/self-care units with less staff resources. The 3-month weight loss increase may be related to the suppression of intradialytic snack that impacted mostly the more malnourished patients or patients with lower interdialytic weight gain. These consequences of the COVID-19 crisis on COVID-free HD patients must be recognized and corrected to prevent further deleterious effects on pat...
Source: Blood Purification - August 26, 2021 Category: Hematology Source Type: research

St. John ’s Wort ( < b > < i > Hypericum perforatum < /i > < /b > )-Related Acute Kidney Injury
Some herbal products were reported to cause nephrotoxicity through different mechanisms. This case report defines an acute kidney injury (AKI) in a patient who usedHypericum perforatum tea as a sleep disorder remedy. The patient developed AKI after ingestion of tea prepared fromHypericum perforatum and underwent hemodialysis because of acute kidney failure. After 1 week, the kidney recovered, and she was discharged with normal kidney function. This is the first case reported having acute kidney failure caused by ingestion ofHypericum perforatum.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 24, 2021 Category: Hematology Source Type: research

Endotoxemia in Critically Ill Patients with COVID-19
Conclusion: Elevated EA was observed in a large majority of critically ill patients with COVID-19 and multi-organ dysfunction despite a low incidence of concurrent gram-negative bacteremia. While we observed that elevated EA and nonresponsiveness to EA were associated with AKI in critically ill patients with COVID-19, these findings require further validation in larger longitudinal cohorts.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 20, 2021 Category: Hematology Source Type: research

Hemoperfusion with CytoSorb ® in Critically Ill COVID-19 Patients
Conclusion: Treatment with CytoSorb in critically ill COVID-19 patients was associated with decreased IL-6 improvement in oxygenation. However, these effects cannot be confirmed as the direct effects of CytoSorb owing to lack of controls. Establishing causality requires large-scale randomized clinical trials.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 18, 2021 Category: Hematology Source Type: research

What Total Body Water Measurement Should Be Used for Prescribing the Dialysis Dose in Low-Flow Home Daily Dialysis?
Conclusion: BIS-TBW and Watson-TBW estimation have a good correlation; however, Watson ’s equation overestimates TBW. This overestimation is negligible for a prescription frequency of #x3e;5 sessions per week.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 17, 2021 Category: Hematology Source Type: research

Improved Dialysis Removal of Protein-Bound Uraemic Toxins with a Combined Displacement and Adsorption Technique
Conclusions: The concept of combined displacement- and adsorption-based dialysis may open up new avenues and possibilities in the field of dialysis to further enhance PBUTs removal in end-stage renal disease.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 16, 2021 Category: Hematology Source Type: research

Hyperoncotic Albumin Solution in Continuous Renal Replacement Therapy Patients
Conclusions: RENAL trial patients commonly received albumin in varying concentrations. The administration of 20% HAS was associated with a more negative fluid balance but was not independently associated with increased mortality or RRT dependence when compared to 4% HAS only.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 12, 2021 Category: Hematology Source Type: research

How Dialysis Patients Cope with a Curfew? A Comparison of Psychological Status between Hemodialysis and Peritoneal Dialysis Patients During the COVID-19 Pandemic
Conclusion: During the social isolation period due to the COVID-19 pandemic, HD patients had better mood profiles than PD patients. A more stable daily routine, an uninterrupted face-to-face contact with health-care workers, and social support among patients in the in-center dialysis environment might be the cause of the favorable mood status. PD patients might need additional psychological support during those periods.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 12, 2021 Category: Hematology Source Type: research

Gut Microbiome-Derived Uremic Toxin Levels in Hemodialysis Patients on Different Phosphate Binder Therapies
Conclusion: There was no difference in the gut microbiome-derived UTOX levels between phosphate binders (SFO vs. SEV), despite SFO therapy resulting in fewer constipated participants. This pilot study may inform study design of future clinical trials and highlights the importance of including factors beyond bowel habits and their association with UTOX levels.Blood Purif (Source: Blood Purification)
Source: Blood Purification - August 10, 2021 Category: Hematology Source Type: research

Hemoperfusion with CytoSorb to Manage Multiorgan Dysfunction in the Spectrum of Hemophagocytic Lymphohistiocytosis Syndrome in Critically Ill Children
Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition characterized by a state of hyperinflammation. Blood purification techniques can blunt the inflammatory process with a rapidly relevant nonselective effect on the cytokine storm, thus potentially translating into survival benefit for these patients. In this cohort, we evaluated the impact of hemoadsorption with CytoSorb combined with continuous kidney replacement therapy used as adjunctive therapy in 6 critically ill children with multiple organ dysfunction due to HLH. In our series, we found a reduction in inflammatory biomarkers in patients with HLH...
Source: Blood Purification - August 3, 2021 Category: Hematology Source Type: research