Criteria for Continuous Kidney Replacement Therapy Cessation in ICU Patients
Conclusions: CKRT cessation in clinical practice is mostly based on spontaneously increasing diuresis, absence of fluid overload, and improvement in creatinine clearance and is often delayed until filter clotting or disconnection of the circuit because of logistic reasons.Blood Purif (Source: Blood Purification)
Source: Blood Purification - April 19, 2022 Category: Hematology Source Type: research
Renal Replacement Therapy for Patients Requiring Extracorporeal Membrane Oxygenation: A Multicenter International Survey
Conclusion: The present study showed significant heterogeneity in RRT practices in patients on ECMO. The lower experience of the DC group, the high rates of concerns toward DCRE, and pressure alarm issues suggested that protocols and training may overcome reluctance and technical difficulties.Blood Purif (Source: Blood Purification)
Source: Blood Purification - April 7, 2022 Category: Hematology Source Type: research
Extracorporeal Removal of Myoglobin in Patients with Rhabdomyolysis and Acute Kidney Injury: Comparison of High and Medium Cut-Off Membrane and an Adsorber Cartridge
Conclusions: Novel MCO membrane might represent the optimal mode of treatment of severe rhabdomyolysis-associated AKI, as it allows for efficient removal of myoglobin, avoids albumin supplementation and is associated with lower costs. For patients requiring cytokine removal, the adsorption capsule can simultaneously reduce cytokine and myoglobin levels.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 25, 2022 Category: Hematology Source Type: research
Multi-Organ Point-Of-Care Ultrasound in Acute Kidney Injury
Acute kidney injury (AKI) is a clinical syndrome caused by a multitude of hemodynamic, toxic, and structural insults to the kidney, and portends worse patient outcomes. Despite careful history taking, physical examination, and analysis of laboratory data, a void is evident in the diagnostic process and clinical monitoring of AKI. Point-of-care ultrasonography (POCUS) is a limited ultrasound study performed by the clinician at bedside as an adjunct to physical examination. Growing body of evidence points to POCUS as a powerful tool in a variety of clinical settings. Herein, we discuss how nephrologist-performed POCUS has th...
Source: Blood Purification - March 18, 2022 Category: Hematology Source Type: research
Preoperative Cardiac Index as a Predictor of Maturation and Primary Patency of Radiocephalic Arteriovenous Fistula in Hemodialysis
Conclusion: This study demonstrated that preoperative CI was associated with RCAVF M and long-term patency. A decreased CI may be a possible predictor of an increased risk of FM and a shorter primary patency time.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 14, 2022 Category: Hematology Source Type: research
Comparative Effectiveness between Expanded Hemodialysis (Hemodialysis Using a Medium Cut-Off Dialyzer) and Mixed-Dilution Online Hemodiafiltration Using a High-Flux Dialyzer in Removing Middle-Molecule Uremic Toxins
Conclusion: Expanded HD (HD + MCO) provided similar effectiveness in removing various uremic toxins and could exhibit greater removal of large middle-molecule uremic toxins, such as α1M and λFLC. Expanded HD can be used as an effective alternative option for mixed-dilution olHDF.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 11, 2022 Category: Hematology Source Type: research
Clinical Assessment of Continuous Hemodialysis with the Medium Cutoff EMiC < b > ® < /b > 2 Membrane in Patients with Septic Shock
In this study, medium cutoff (MCO) continuous venovenous hemodialysis (CVVHD) was compared to high-flux membrane continuous venovenous hemodiafiltration (CVVHDF) in terms of hemodynamic improvement, efficiency, middle molecule removal, and inflammatory system activation.Methods: This is a monocenter crossover randomized study. Between December 31, 2017, and December 31, 2019, 20 patients with septic shock and stage 3 acute kidney injury (AKI) admitted to 2 Italian ICUs were enrolled. All patients underwent CVVHD with Ultraflux ® EMiC®2 and CVVHDF with AV1000S® without washout. Each treatment lasted 24 h.Results: Compare...
Source: Blood Purification - March 9, 2022 Category: Hematology Source Type: research
A Therapeutic Extracorporeal Device for Specific Removal of Pathologic Asymmetric Dimethylarginine from the Blood
Conclusion: A new, safe, and effective extracorporeal approach to lower ADMA was developed which may have application in improving outcomes in patients with vascular complications and risk of mortality associated with high ADMA.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 4, 2022 Category: Hematology Source Type: research
Impact of Double-Machine Replacement Protocol at Start of Continuous Renal Replacement Therapy in Vasopressor-Dependent Patients: A Retrospective Cohort Study
Conclusions: Implementation of the DMRP for CRRT circuit replacement had a slight hemodynamic effect on vasopressor-dependent patients. It also reduced the pause time and volume of circuit purging and priming fluid related to CRRT circuit replacement compared with SMRP.Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 4, 2022 Category: Hematology Source Type: research
The Next Evolution of HemoDialysis eXpanded: From a Delphi Questionnaire-Based Approach to the Real Life of Italian Dialysis Units
Blood Purif (Source: Blood Purification)
Source: Blood Purification - March 1, 2022 Category: Hematology Source Type: research
Fluctuations in Interleukin-6 Levels during Hemodialysis Sessions with Medium Cutoff Membranes: An Analysis on COVID-19 Case Series
Conclusion: This study describes over time variations in IL-6 levels of COVID-19 patients undergoing HD with MCO membranes. The trend for the changes of IL-6 levels during dialysis sessions was not uniform for all patients. Surviving patients had decreasing levels of IL-6 with consecutive dialysis sessions, while nonsurvivors had an increasing trend.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 17, 2022 Category: Hematology Source Type: research
Comparison of Body Fluid Volumes Determined by Kinetic Modeling and by Bioimpedance Spectroscopy
Conclusion: Fluid volumes in different body compartments can be estimated by kinetic modeling as well as by the BIS method.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 11, 2022 Category: Hematology Source Type: research
The Efficacy of Early Additional Hemoperfusion Therapy for Severe COVID-19 Patients: A Prospective Cohort Study
Conclusions: The addition of early HA-330 hemoperfusion to standard therapy improved severity of organ failure and might reduce the mortality rate. However, the results were affected by the baseline confounders and limited sample size.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 9, 2022 Category: Hematology Source Type: research
Benefit of Hemoadsorption Therapy in Patients Suffering Sepsis-Associated Acute Kidney Injury: A Case Series
Conclusion: In conclusion, it seems that applying the CytoSorb in combination with CRRT in ICU septic patients with AKI, is related to a significant decrease in mortality, if the integrity and continuity of the treatment be kept, as much as possible. This study presented an effectively positive outcome with cytokine adsorber treatment as an adjuvant along with standard treatment in a high-risk mortality case of septic shock with organ failure.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 2, 2022 Category: Hematology Source Type: research
Safety of Intradialytic Bamlanivimab/Etesevimab Administration in Two COVID-19 Dialysis Outpatients
Conclusions: Intradialytic administration of Bamlanivimab/Etesevimab could be considered safe and may allow adequate clinical observation time without hospital-stay prolongation.Blood Purif (Source: Blood Purification)
Source: Blood Purification - February 2, 2022 Category: Hematology Source Type: research
